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公开(公告)号:US20180193077A1
公开(公告)日:2018-07-12
申请号:US15912038
申请日:2018-03-05
发明人: Kelly W. Schlachter , Daniel A. Shimko , Kerem Kalpakci , Erick Vasquez , David R. Kaes , Subhabrata Bhattacharyya
IPC分类号: A61B17/88 , B01F15/02 , B01F13/06 , B01F13/00 , B01F15/00 , A61F2/28 , A61F2/30 , A61F2/46 , A61L27/36 , A61L27/54
CPC分类号: A61B17/8816 , A61B17/8805 , A61B2017/8838 , A61F2/28 , A61F2/30942 , A61F2/4601 , A61F2/4644 , A61F2002/2835 , A61L27/3608 , A61L27/365 , A61L27/3683 , A61L27/3691 , A61L27/54 , A61L2300/412 , A61L2430/02 , B01F13/0023 , B01F13/06 , B01F15/00506 , B01F15/0278
摘要: A bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of milled and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder on the coherent mass. In some embodiments, a method of implanting a bone material is provided, the method comprising contacting the bone material with a liquid, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass; molding the bone material into a shape to implant the bone material; and implanting the bone material at the target tissue site.
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公开(公告)号:US09913676B2
公开(公告)日:2018-03-13
申请号:US14941033
申请日:2015-11-13
发明人: Kelly W. Schlachter , Daniel A. Shimko , Kerem N. Kalpakci , Erick Vasquez , David R. Kaes , Subhabrata Bhattacharyya
IPC分类号: A61F2/28 , A61B17/88 , A61F2/30 , A61L27/36 , A61L27/54 , B01F13/00 , B01F13/06 , B01F15/00 , B01F15/02 , A61F2/46
CPC分类号: A61B17/8816 , A61B17/8805 , A61B2017/8838 , A61F2/28 , A61F2/30942 , A61F2/4601 , A61F2/4644 , A61F2002/2835 , A61L27/3608 , A61L27/365 , A61L27/3683 , A61L27/3691 , A61L27/54 , A61L2300/412 , A61L2430/02 , B01F13/0023 , B01F13/06 , B01F15/00506 , B01F15/0278
摘要: A bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of milled and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder on the coherent mass. In some embodiments, a method of implanting a bone material is provided, the method comprising contacting the bone material with a liquid, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass; molding the bone material into a shape to implant the bone material; and implanting the bone material at the target tissue site.
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公开(公告)号:US20180044638A1
公开(公告)日:2018-02-15
申请号:US15232275
申请日:2016-08-09
CPC分类号: C12N5/0654 , A61F2/4644 , A61F2250/0067
摘要: A tissue treatment apparatus and method for treating bone tissue has a controller, an enclosure, a reagent supply system, a draining configuration, and a gas relief valve is controlled by the controller. A bioactive agent may be applied through the reagent supply system. Optionally provided is a gas evacuation assembly, a gas supply unit, a thermal unit for heating or cooling reagents or gases, a sonication unit, any or each operated by the controller. The method provides for programming controller to effect a treatment procedure. In an embodiment of the present application the treatment procedure effects demineralization of the bone material.
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公开(公告)号:US20170216491A1
公开(公告)日:2017-08-03
申请号:US15008676
申请日:2016-01-28
CPC分类号: A61L27/3691 , A61L2/087 , A61L27/3608 , A61L27/365 , A61L27/54 , A61L2202/11 , A61L2202/21 , A61L2300/412 , A61L2430/02
摘要: A method of making an electron beam irradiated osteoinductive implant is provided. The method comprises exposing an osteoinductive implant containing demineralized bone matrix (DBM) fibers to electron beam radiation at a dose of from about 10 kilograys to 100 kilograys for a period of time. The electron beam irradiation reduces microorganisms in the osteoinductive implant, and the electron beam irradiated osteoinductive implant retains osteoinductive properties. Methods of implantation and an irradiated osteoinductive implant are also disclosed.
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公开(公告)号:US09034052B2
公开(公告)日:2015-05-19
申请号:US13740357
申请日:2013-01-14
CPC分类号: A61F2/4601 , A61F2/2846 , A61F2002/30588 , A61F2002/30738
摘要: A delivery system comprising a covering containing at least a first substance for release to a surgical site is provided. The covering includes an elongated containment portion having at least one compartment, wherein the covering includes an elongated containment having a first end and a second end. At one end the elongated containment defines an opening configured to receive at least one substance. The at least one substance can be DBM or a mixture of demineralized fibers and particles in a ratio of 30:70. The delivery system also includes a closing member that can close the elongated containment prior to insertion at a surgical site. The closing member can be drawing strings, stitches, sutures, wing sutures, heat seals, adhesion, pressure fittings, coil ring, twist tie. The substance contained in the delivery system can also be enclosed by twisting and folding over a portion of the covering.
摘要翻译: 提供一种包含至少包含用于释放到手术部位的第一物质的覆盖物的递送系统。 覆盖物包括具有至少一个隔室的细长的容纳部分,其中所述覆盖物包括具有第一端和第二端的细长的容纳物。 在一端,细长的容纳物限定了构造成容纳至少一种物质的开口。 所述至少一种物质可以是DBM或软化纤维和颗粒的混合物,其比例为30:70。 递送系统还包括关闭构件,其可以在插入手术部位之前关闭细长的容纳物。 关闭构件可以是拉丝,缝合,缝线,翼缝合,热封,粘合,压力配件,线圈环,扭结带。 包含在输送系统中的物质也可以通过在覆盖物的一部分上扭曲和折叠来包围。
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公开(公告)号:US20140261855A1
公开(公告)日:2014-09-18
申请号:US13829416
申请日:2013-03-14
IPC分类号: A61F2/46
CPC分类号: A61B17/8811 , A61B17/8802 , A61B2017/00893 , A61B2017/00933 , A61B2017/00964 , A61F2/28 , A61F2/4601 , A61F2002/2835 , A61F2002/30062 , A61F2002/30588 , A61F2002/30784 , A61F2002/4495
摘要: A filling system for delivery of at least one substance to a covering is provided. The filling system comprises at least a funnel shaped container and a plunger. The funnel shaped container includes a scoop portion connected to a hollow barrel. The barrel is configured for insertion into the covering, the plunger adapted for pushing the at least one substance down the hollow barrel into the covering. The filling system can also include a spatula. A kit including a funnel shaped container, a plunger adapted to push a substance down the barrel of the funnel shaped container, a spatula, a retainer for keeping the kit elements in place and trays for protecting them from the environment are also provided. A method of use utilizing the filling system is also provided.
摘要翻译: 提供了用于将至少一种物质输送到覆盖物的填充系统。 填充系统至少包括漏斗形容器和柱塞。 漏斗形容器包括连接到中空筒的勺部分。 筒被配置成插入到覆盖物中,柱塞适于将中空筒的至少一种物质推入覆盖物中。 填充系统还可以包括刮铲。 还提供了一种套件,其包括漏斗形容器,适于将物质向下推动漏斗形容器的筒体的柱塞,刮铲,用于将套件元件保持在适当位置的保持器以及用于将其保护于环境的托盘。 还提供了利用填充系统的使用方法。
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公开(公告)号:US12042403B2
公开(公告)日:2024-07-23
申请号:US18094690
申请日:2023-01-09
CPC分类号: A61F2/4601 , A61B17/8833 , A61B17/8863 , A61B50/33 , A61F2/4644 , A61B2017/00871 , A61B2017/8838 , A61B2050/314 , A61B2090/0817
摘要: A bone material dispensing apparatus for preparing, mixing, and dispensing bone material into a foldable container is provided. In some embodiments, the dispensing apparatus comprises a tray and a foldable container. The tray includes a mixing surface, a dispensing surface and a means to measure the amount of material to be dispensed. A kit including a tray, a foldable container, and a spatula are also provided. A method of using the dispensing apparatus to deliver the bone material to a bone detect is also provided.
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公开(公告)号:US12035936B2
公开(公告)日:2024-07-16
申请号:US16822832
申请日:2020-03-18
发明人: Susan J. Drapeau , Daniel A. Shimko
IPC分类号: A61B18/00 , A61B17/32 , A61B17/3205 , A61B18/14 , A61B17/00 , A61B17/22 , A61B17/221 , A61B17/30
CPC分类号: A61B17/32056 , A61B17/320016 , A61B18/1482 , A61B2017/00349 , A61B17/22031 , A61B2017/22079 , A61B2017/2215 , A61B2017/306 , A61B2017/32004 , A61B17/32053 , A61B2018/141 , A61B2217/005 , A61B2218/007
摘要: Ablation devices useful for removing nerve and soft tissue via a minimally invasive procedure to alleviate pain are provided. The device comprises a cannula having an opening at a distal tip of the cannula, the opening configured for suction of a surgical site, and a movable tissue capture member having a portion disposed within the opening or adjacent to the cannula, the movable tissue capture member configured to capture tissue when moved in a first position. Methods for ablating nerve and/or soft tissue utilizing the ablation devices are also provided.
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公开(公告)号:US12004791B2
公开(公告)日:2024-06-11
申请号:US18094736
申请日:2023-01-09
发明人: Daniel A. Shimko , Jared J. Diegmueller , Jonathan M. Dewey , Kerem N. Kalpakci , Erick Vasquez
CPC分类号: A61B17/8833 , A61B17/8816 , A61B17/8825 , A61F2/28 , A61F2/4601 , A61B2017/564 , A61B2017/8838 , A61F2002/2835
摘要: A device for hydrating particulate bone material is provided. The device comprises a tubular member having an interior surface and an exterior surface. The interior surface is configured to receive the particulate bone material and a hydration fluid. The exterior surface has a plurality of pores configured to allow the hydration fluid to flow into the interior surface of the tubular member and hydrate the particulate bone material. The plurality of pores are smaller in size than the particulate bone material. Methods of dispensing particulate the bone material are also provided.
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公开(公告)号:US20230157740A1
公开(公告)日:2023-05-25
申请号:US18094736
申请日:2023-01-09
发明人: Daniel A. Shimko , Jared J. Diegmueller , Jonathan M. Dewey , Kerem N. Kalpakci , Erick Vasquez
CPC分类号: A61B17/8833 , A61F2/28 , A61F2/4601 , A61B17/8825 , A61B17/8816 , A61F2002/2835 , A61B2017/8838 , A61B2017/564
摘要: A device for hydrating particulate bone material is provided. The device comprises a tubular member having an interior surface and an exterior surface. The interior surface is configured to receive the particulate bone material and a hydration fluid. The exterior surface has a plurality of pores configured to allow the hydration fluid to flow into the interior surface of the tubular member and hydrate the particulate bone material. The plurality of pores are smaller in size than the particulate bone material. Methods of dispensing particulate the bone material are also provided.
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