摘要:
The invention provides certain cycloalkyl-fused tetrahydroquinolines of the Formula (I), and their pharmaceutically acceptable salts and esters, wherein R1, R2, R7, R8, R8a, E, Y, Z, n, u, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH2 function.
摘要:
The invention provides methods and compositions for inhibiting tumor growth in a mammal. The methods comprise administering to the mammal a synergistic combination of (7α)-21-[4-[(Diethylamino)methyl]-2-methoxyphenoxy]-7-methyl-19-norpregna-1,3,5(10)-trien-3-ol 2-hydroxy-1,2,3-propanetricarboxylate and a synergistic chemotherapeutic drug. The combination of the compounds more than additively inhibits growth of tumor cells.
摘要:
An apparatus to introduce a reagent to reduce nitrogen oxides in flue gas including: nozzles mounted to a passage for the flue gas, wherein the nozzles are mounted downstream of a SNCR system and upstream of a SCR system, wherein the nozzles are mounted on one or more walls of the passage and are configured to inject a pressurized fluid into the flue gas; a source of the pressurized fluid which is in fluid communication with the nozzles such that the pressurized fluid flows to the nozzles; a source of a NOx reducing reagent and a mixing device which mixes the reagent with the pressurized fluid such that the pressurized fluid flowing to the nozzles includes the reagent.
摘要:
A tie down anchor that is particularly useful when tying down objects to the ground and may take the place of ordinary tent stakes due to the tie down anchor's superior holding ability when compared to traditional tent stakes. The tie down anchor has a guide having an angled hole. A main stake extends downwardly from the guide and the main stake includes an aperture. A locking spike is adapted for being received in the angled hole. The aperture in the main stake is positioned to receive the locking stake when the locking stake passes through the angled hole. The stake of this invention is small, light, and of a comparable size to traditional tent stakes.
摘要:
A method of transmitting a coded media frame comprises determining a plurality of media frame sizes including a media frame size, transmitting an element comprising the plurality of media frame sizes, and thereafter receiving an input media frame. The method also includes processing the input media frame according to the media frame size to provide a coded media frame, and transmitting the coded media frame.
摘要:
Provided are mRNA translational enhancer elements (TEEs), e.g., SEQ ID NOs:1-35. Also provided are translational enhancer polynucleotides that comprise one or more of the specific TEEs exemplified herein or their variants, homologs or functional derivatives. Further provided are expression vectors comprising such TEEs or translational enhancer polynucleotides, as well as host cells and expression systems that harbor such vectors.
摘要:
A method and apparatus for obtaining inspection information is described. A standard CCD or CMOS camera is used to obtain images in the near infrared region. Background and noise components of the obtained image are removed and the signal to noise ratio is increased to provide information that is suitable for use in inspection.
摘要:
A disk brake comprising: a brake disk, a moving disk, a fixed disk, a mounting base, a guide rod, a fixed rod, first and second levers, a fixed plate, and first and second spring clamps. Here, one end of the fixed rod is fixed to a plane of the moving disk, the other end of the fixed rod passes through the fixed disk and is fixed to one end of the first/second lever, and the other end of the first/second lever is fixed to the circumferential surface of the fixed disk on the center line of the fixed disk; the fixed plate is fixed to either the guide rod or the mounting base; one end of the first/second spring clamp is connected to the fixed plate, and the other end of the first/second spring clamp is clamped at the middle position between the first and second levers.
摘要:
Systems and methods for analyzing combustion system operation are provided. According to one embodiment, a method can include receiving multiple CO measurements from respective CO sensors distributed within a combustion system; receiving multiple O2 measurements from respective O2 sensors distributed within the combustion system; and determining at least one operating condition of the combustion system based at least in part on CO indicated by the CO measurements relative to O2 indicated by the O2 measurements.
摘要:
A disk brake for a traction machine having a damping height of a damping mechanism that can be adjusted integrally. According to one embodiment, a disk brake includes: a static iron core; a spring and a coil assembly in the static iron core; a dynamic iron core assembly including a dynamic iron core, a dynamic disk, and first and second friction rotors configured to fit with the dynamic iron core and the dynamic disk; a plurality of connecting bolts; a plurality of spacers; a damping mechanism on the dynamic iron core assembly, the damping mechanism including a plurality of damping components on the dynamic iron core; an adjusting toothed belt assembly coupled to the damping components and banded to a circumferential outer surface of the dynamic iron core; and an adjusting bracket on the dynamic iron core and coupled to the adjusting toothed belt assembly.