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231 条记录 (耗时 0.046 秒)

    Synergistic anti-proliferation activity of TAS-108 with mTOR inhibitors against cancer cells
    1.
    发明申请
    Synergistic anti-proliferation activity of TAS-108 with mTOR inhibitors against cancer cells 审中-公开
    TAS-108与mTOR抑制剂对癌细胞的协同抗增生活性

    公开(公告)号：US20130231292A1

    公开(公告)日：2013-09-05

    申请号：US13784734

    申请日：2013-03-04

    申请人： Wei Zhou ,  Lidia Sambucetti

    发明人： Wei Zhou ,  Lidia Sambucetti

    IPC分类号： A61K31/573 ,  A61K31/337 ,  A61K31/436 ,  A61K38/08 ,  A61K45/06

    CPC分类号： A61K31/573 ,  A61K31/337 ,  A61K31/436 ,  A61K38/08 ,  A61K45/06 ,  A61K2300/00

    摘要： The invention provides methods and compositions for inhibiting tumor growth in a mammal. The methods comprise administering to the mammal a synergistic combination of (7α)-21-[4-[(Diethylamino)methyl]-2-methoxyphenoxy]-7-methyl-19-norpregna-1,3,5(10)-trien-3-ol 2-hydroxy-1,2,3-propanetricarboxylate and a synergistic chemotherapeutic drug. The combination of the compounds more than additively inhibits growth of tumor cells.

    摘要翻译： 本发明提供用于抑制哺乳动物肿瘤生长的方法和组合物。 所述方法包括向哺乳动物施用（7α）-21- [4 - [（二乙基氨基）甲基] -2-甲氧基苯氧基] -7-甲基-19-去甲基-3,3,5（10）三烯的协同组合 -3-醇2-羟基-1,2,3-丙基三羧酸酯和协同化疗药物。 化合物的组合多于相加地抑制肿瘤细胞的生长。

    Tie down ground anchor head
    4.
    发明授权
    Tie down ground anchor head 有权

    公开(公告)号：US11643785B2

    公开(公告)日：2023-05-09

    申请号：US17033152

    申请日：2020-09-25

    申请人： Wei Zhou ,  Alivia Faye Zhou

    发明人： Wei Zhou ,  Alivia Faye Zhou

    IPC分类号： E02D5/80 ,  E04H12/22 ,  E04B1/343

    CPC分类号： E02D5/801 ,  E04B1/34347 ,  E04H12/2223 ,  E02D2200/1671

    摘要： An anchor head mounted to or incorporated into the shaft of conventional tie down stakes and earth anchors. The anchor head eliminates the need to manually drive the earth anchor into the ground and allows the anchor to be placed and removed using conventional powered drill/drivers and hex sockets or wrenches. The anchor head has a hexagonal top section and a hexagonal bottom sectional separated by an integral, central annular shoulder. The top and bottom sections are each configured to have six equilateral side walls and dimensioned to receive two different sizes of wrench or hex socket. The bottom section of the anchor head has a threaded axial bore for receiving the threaded end of the anchor shaft. The bottom section also has a lateral “swage” bore through which a punch is inserted to swage or deform the threads of the shaft to permanently secure the anchor head to the shaft.

    METHODS AND SYSTEMS FOR SEQUENCING LONG NUCLEIC ACIDS
    10.
    发明申请
    METHODS AND SYSTEMS FOR SEQUENCING LONG NUCLEIC ACIDS 审中-公开
    用于测序长核酸的方法和系统

    公开(公告)号：US20140315724A1

    公开(公告)日：2014-10-23

    申请号：US14009089

    申请日：2012-04-02

    申请人： Wei Zhou ,  Rui Mei ,  Filip Crnogorac ,  Guochun Liao ,  Julian Lucas

    发明人： Wei Zhou ,  Rui Mei ,  Filip Crnogorac ,  Guochun Liao ,  Julian Lucas

    IPC分类号： C12Q1/68

    摘要： The present invention provides methods and systems for sequencing long nucleic acid fragments. In one aspect of the invention, methods, systems and reagent kits are provided for sequencing nucleic acid target sequences. Some embodiments of the methods, systems and reagent kits are particularly suitable for sequencing a large number of fragments, particularly long fragments.

    摘要翻译： 本发明提供了用于测序长核酸片段的方法和系统。 在本发明的一个方面，提供了用于测序核酸靶序列的方法，系统和试剂盒。 方法，系统和试剂盒的一些实施方案特别适用于测序大量片段，特别是长片段。