公开(公告)号：US20140038250A1

公开(公告)日：2014-02-06

申请号：US14111425

申请日：2012-04-13

申请人： Sang-Hyun Lee ,  Moon-Ho Eom ,  Julia Lee ,  Sang-Jun Jeon ,  Jung-Hee Cho ,  Jin Dal Rae Choi

发明人： Sang-Hyun Lee ,  Moon-Ho Eom ,  Julia Lee ,  Sang-Jun Jeon ,  Jung-Hee Cho ,  Jin Dal Rae Choi

IPC分类号： C12M1/00 ,  C12P7/28 ,  C12P7/06 ,  C12P7/16

CPC分类号： C12P7/06 ,  B01D15/08 ,  B01D15/1885 ,  C12M21/12 ,  C12M23/58 ,  C12M25/18 ,  C12M25/20 ,  C12M47/10 ,  C12M47/12 ,  C12P7/065 ,  C12P7/16 ,  C12P7/28 ,  Y02E50/10 ,  Y02E50/17

摘要： The present invention relates to an apparatus and a method for fermenting, separating, and refining a product, which is produced by cultivating a microorganism. The apparatus and the method for fermenting, separating, and refining, of the present invention, can separate and refine the product that is produced by microbial fermentation in a simple, continuous manner and with high efficiency.

摘要翻译： 本发明涉及通过培养微生物产生的产品的发酵，分离和精制的装置和方法。 本发明的发酵，分离和精制的装置和方法可以以简单，连续的方式和高效率分离和精制由微生物发酵产生的产物。

公开(公告)号：US08642302B2

公开(公告)日：2014-02-04

申请号：US13316963

申请日：2011-12-12

申请人： James L. Gaddy ,  Dinesh K. Arora ,  Ching-Whan Ko ,  John Randall Phillips ,  Rahul Basu ,  Carl V. Wilkstrom ,  Edgar C. Clausen

发明人： James L. Gaddy ,  Dinesh K. Arora ,  Ching-Whan Ko ,  John Randall Phillips ,  Rahul Basu ,  Carl V. Wilkstrom ,  Edgar C. Clausen

IPC分类号： C12P7/06

CPC分类号： C12P7/065 ,  C12M21/04 ,  C12M21/12 ,  C12M29/02 ,  C12M29/18 ,  C12M43/02 ,  Y02E50/17 ,  Y02E50/343

摘要： A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing in a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.

公开(公告)号：US20140024826A1

公开(公告)日：2014-01-23

申请号：US13980419

申请日：2012-01-20

申请人： Neelakantam V. Narendranath ,  Steven T. Bly

发明人： Neelakantam V. Narendranath ,  Steven T. Bly

IPC分类号： C07H1/08

CPC分类号： C07H1/08 ,  B01D61/022 ,  B01D61/027 ,  B01D2311/04 ,  B01D2311/12 ,  B01D2311/18 ,  B01D2311/2649 ,  B01D2315/16 ,  B01D2317/022 ,  C12M21/12 ,  C12M43/02 ,  C12M45/04 ,  C12M45/06 ,  C12P7/10 ,  C12P2201/00 ,  C13K1/02 ,  C13K1/06 ,  C13K13/002 ,  Y02E50/16 ,  Y02E50/17

摘要： Systems and methods for increasing fermentation efficiency of a lignocellulosic hydrolysate are disclosed. The system comprises a filter configurable to remove matter having a particle size of larger than about 25 to 100 microns from the liquid component, and at least one nanofilter configurable to remove acids from the liquid component. An apparatus is used to adjust the pH of the nanofiltered liquid component using a calcium hydroxide composition to a pH of about 5.5 to 6.0. The calcium hydroxide composition includes calcium hydroxide alone or in combination with either ammonium hydroxide and/or potassium hydroxide. The biomass comprises lignocellulosic material including at least one of corncob, corn plant husk, corn plant leaves, and corn plant stalks.

摘要翻译： 公开了提高木质纤维素水解产物发酵效率的系统和方法。 该系统包括可配置成从液体组分去除具有大于约25至100微米的粒度的物质的过滤器，和至少一种能够从液体组分中除去酸的纳米过滤器。 使用一种装置来使用氢氧化钙组合物调节纳滤滤液体组分的pH至约5.5至6.0的pH。 氢氧化钙组合物包括单独的氢氧化钙或与氢氧化铵和/或氢氧化钾的组合。 生物质包含木质纤维素材料，其包括玉米芯，玉米植物壳，玉米植物叶和玉米植物茎中的至少一种。

公开(公告)号：US08633003B2

公开(公告)日：2014-01-21

申请号：US13026613

申请日：2011-02-14

申请人： Travis Brotherson

发明人： Travis Brotherson

IPC分类号： C12P7/06

CPC分类号： C12P7/10 ,  C12M21/12 ,  C12M43/00 ,  C12P7/08 ,  C12P7/14 ,  C12P2201/00 ,  Y02E50/16 ,  Y02E50/17

摘要： A process of producing ethanol from whole stillage, includes obtaining a supply of whole stillage from an ethanol production facility after ethanol has been extracted therefrom; pre-treating the whole stillage to convert hemicellulose portions of the whole stillage into sugars; adding enzymes to the whole stillage to convert cellulose portions of the whole stillage to sugars; fermenting the whole stillage to create a beer mixture; and distilling the beer mixture to separate ethanol therefrom. The pre-treating step may include adding acid to the whole stillage to decrease its pH level; heating and pressurizing the whole stillage; holding the whole stillage under pressure and heat for a dwell time; removing pressure from the whole stillage to cause flashing; and cooling the whole stillage before the enzymes are added.

公开(公告)号：US20130309761A1

公开(公告)日：2013-11-21

申请号：US13982420

申请日：2012-03-23

申请人： Akira Nishimura ,  Takahiro Yamauchi ,  Kentaro Ogura ,  Haruka Nishimoto ,  Hiroyuki Kurihara ,  Atsushi Minamino ,  Hideo Suzuki ,  Gaku Kondo

发明人： Akira Nishimura ,  Takahiro Yamauchi ,  Kentaro Ogura ,  Haruka Nishimoto ,  Hiroyuki Kurihara ,  Atsushi Minamino ,  Hideo Suzuki ,  Gaku Kondo

IPC分类号： C12M1/00

CPC分类号： C12M43/00 ,  C12M21/12 ,  C12M21/18 ,  C12M47/10 ,  C13B20/165 ,  C13K1/02 ,  C13K13/002

摘要： There is provided an apparatus for treating a biomass feedstock at a high temperature, including a cooling means for cooling a biomass treated liquid at a high temperature; an enzymatic saccharification tank for saccharifying a cooled treated liquid with an enzyme; a solid-liquid separation apparatus for removing water-slightly soluble substances contained in a saccharide solution taken out from the enzymatic saccharification tank and a foreign substance removing unit provided with a microfiltlation (MF) membrane; a dilution tank, disposed downstream of the foreign substance removing unit, for diluting the saccharide solution from which the water-slightly soluble substances are removed by adding water thereto; a water separation unit, provided with a reverse osmosis (RO) membrane, for removing water from the diluted saccharide solution so as to obtain concentrated saccharide solution.

摘要翻译： 提供了一种用于在高温下处理生物质原料的装置，包括用于在高温下冷却生物质处理液体的冷却装置; 用于用酶糖化冷却的处理液的酶糖化罐; 用于除去从所述酶糖化槽取出的糖溶液中所含的微小水溶性物质的固液分离装置和具有微滤膜（MF）膜的异物去除单元; 设置在异物去除单元的下游的稀释槽，用于稀释通过向其中加入水来除去水 - 微溶物质的糖溶液; 设置有反渗透膜（RO）膜的水分离单元，用于从稀释的糖溶液中除去水，以获得浓缩的糖溶液。

公开(公告)号：US08574879B2

公开(公告)日：2013-11-05

申请号：US13325149

申请日：2011-12-14

申请人： James L. Gaddy ,  Dinesh K. Arora ,  Ching-Whan Ko ,  John Randall Phillips ,  Rahul Basu ,  Carl V. Wilkstrom ,  Edgar C. Clausen

发明人： James L. Gaddy ,  Dinesh K. Arora ,  Ching-Whan Ko ,  John Randall Phillips ,  Rahul Basu ,  Carl V. Wilkstrom ,  Edgar C. Clausen

IPC分类号： C12P7/06

CPC分类号： C12P7/065 ,  C12M21/04 ,  C12M21/12 ,  C12M29/02 ,  C12M29/18 ,  C12M43/02 ,  Y02E50/17 ,  Y02E50/343

摘要： A stable continuous method for producing ethanol from the anaerobic bacterial fermentation of a gaseous substrate containing at least one reducing gas involves culturing in a fermentation bioreactor anaerobic, acetogenic bacteria in a liquid nutrient medium; supplying the gaseous substrate to the bioreactor; and manipulating the bacteria in the bioreactor by reducing the redox potential, or increasing the NAD(P)H TO NAD(P) ratio, in the fermentation broth after the bacteria achieves a steady state and stable cell concentration in the bioreactor. The free acetic acid concentration in the bioreactor is maintained at less than 5 g/L free acid. This method allows ethanol to be produced in the fermentation broth in the bioreactor at a productivity of greater than 10 g/L per day. Both ethanol and acetate are produced in a ratio of ethanol to acetate ranging from 1:1 to 20:1.

摘要翻译： 从含有至少一种还原气体的气态底物的厌氧细菌发酵生产乙醇的稳定的连续方法包括在液体营养培养基中的发酵生物反应器中厌氧发酵细菌中培养; 将气态基质供应到生物反应器; 并且在细菌在生物反应器中达到稳定状态和稳定的细胞浓度之后通过降低氧化还原电位或增加发酵液中的NAD（P）H TO NAD（P）比来操纵生物反应器中的细菌。 生物反应器中的游离乙酸浓度保持在低于5g / L游离酸。 该方法允许以每天大于10g / L的生产率在生物反应器中的发酵液中生产乙醇。 乙醇和乙酸乙酯均以乙醇与乙酸乙酯的比例为1：1至20：1生产。

公开(公告)号：US08569040B1

公开(公告)日：2013-10-29

申请号：US13556048

申请日：2012-07-23

申请人： Nils Kroger ,  Stephen J. Miller ,  Nicole Poulsen

发明人： Nils Kroger ,  Stephen J. Miller ,  Nicole Poulsen

IPC分类号： C12N1/12 ,  A01H11/00 ,  A01H3/04 ,  C12P7/20 ,  C12P19/44 ,  A01G7/00

CPC分类号： C12P7/6463 ,  C12M21/02 ,  C12M21/12 ,  C12M23/18 ,  C12N1/12 ,  C12P19/04

摘要： The present invention pertains to compositions and methods for more efficiently and effectively growing microalgae suitable for biofuel production. In one aspect, the invention pertains to a composition comprising microalgae and a suitable growth medium. The suitable growth medium comprises a nutritionally acceptable nitrate salt, and a carbonate salt. The concentration of nutritionally acceptable nitrate salt is from about 75 to about 200 μM while the concentration of carbonate salt is from about 1 to about 6 mM.

摘要翻译： 本发明涉及用于更有效和有效地生长适于生物燃料生产的微藻的组合物和方法。 一方面，本发明涉及包含微藻和合适生长培养基的组合物。 合适的生长培养基包含营养可接受的硝酸盐和碳酸盐。 营养可接受的硝酸盐的浓度为约75至约200μM，而碳酸盐的浓度为约1至约6mM。

公开(公告)号：US20130252299A1

公开(公告)日：2013-09-26

申请号：US13881101

申请日：2011-11-02

申请人： Peter Simpson Bell ,  Brian Henry Cooke ,  Neil Turnbull

发明人： Peter Simpson Bell ,  Brian Henry Cooke ,  Neil Turnbull

IPC分类号： C12P7/06

CPC分类号： C12P7/065 ,  C12M21/12 ,  C12M43/00 ,  Y02E50/17 ,  Y02E50/343

摘要： A process for the production of C2− alcohols from a methane-containing feedstock which process comprises a) optionally reacting in a pre-reformer the methane-containing feedstock in the presence of steam, where the steam plus C02 to methane molar ratio is less than 5:1; b) reforming at least a portion of the methane-containing feedstock in a first reformer optionally in the presence of steam, where the steam plus C02 to methane molar ratio is less than 5:1 to produce a first product stream comprising CO, H2 and C02; c) optionally subjecting at least a portion of the first product stream and/or a portion of the methane containing feedstock to a reforming process in a second reformer in the presence of steam and oxygen to produce a second product stream comprising CO, H2 and C02 d) subjecting the product streams to a bacterial fermentation process in a fermenter to produce a third product stream comprising an aqueous solution of at least one C2− alcohol, nutrients and reaction intermediates and a fourth product stream comprising CO, H2 and C02 at least 60% of the CO being converted; e) recycling at least a portion of the fourth product stream to the methane-containing feedstock; f) recovering at least a part of the at least one C2− alcohols from the third product stream to leave a fifth product stream; and g) recycling at least a part of the fifth product stream to the fermenter.

摘要翻译： 一种从含甲烷原料生产C2-醇的方法，该方法包括：a）在蒸汽存在下，任选地在预重整器中反应含甲烷的原料，其中蒸汽加CO 2与甲烷的摩尔比小于 5：1; b）任选地在蒸汽存在下任选地在第一重整器中重整至少一部分含甲烷原料，其中蒸汽加CO 2与甲烷的摩尔比小于5:1，以产生包含CO，H 2和 C02; c）在蒸汽和氧气的存在下，任选地使至少一部分第一产物流和/或含甲烷原料的一部分在第二重整器中进行重整过程，以产生包含CO，H 2和CO 2的第二产物流 d）使产物流在发酵罐中进行细菌发酵过程，以产生包含至少一种C 2醇，营养物和反应中间体的水溶液的第三产物流和包含CO，H 2和CO 2的第四产物流至少60 CO转化率的百分比; e）将第四产物流的至少一部分再循环到含甲烷的原料中; f）从第三产物流中回收至少一部分至少一种C 2醇以留下第五产物流; 和g）将第五产物流的至少一部分再循环到发酵罐中。

公开(公告)号：US20130236941A1

公开(公告)日：2013-09-12

申请号：US13794741

申请日：2013-03-11

申请人： COBALT TECHNOLOGIES INC.

发明人： Stacy M. Burns-Guydish ,  Anthony F. Cann ,  Dhruti Dalal ,  Lawrence W. Fry ,  Michael S. Hershkowitz ,  William F. McDonald ,  Andrew D. Meyer ,  Victor O. Nava-Salgado ,  Brandon T. Olson ,  Ishmael M. Sonico ,  David C. Walther ,  Yongming Zhu

IPC分类号： C12M1/00 ,  C12N1/20 ,  C12P7/10 ,  C12P7/16 ,  C12P7/28

CPC分类号： C12P7/14 ,  C12M21/12 ,  C12M23/42 ,  C12M33/00 ,  C12M43/02 ,  C12M45/00 ,  C12M45/06 ,  C12M45/20 ,  C12N1/14 ,  C12N1/20 ,  C12P7/10 ,  C12P7/16 ,  C12P7/28 ,  C12P2203/00 ,  Y02E50/10 ,  Y02E50/16

摘要： Systems and methods for producing bioproducts are shown. The systems and methods herein can be configured and used in an integrated biorefinery. The integrated biorefinery may comprise a sugar production facility such as a sugar mill, a production facility for one or more bioproduct(s) such as butanol, and optionally an ethanol production facility employing the system and method.

摘要翻译： 显示生产生物产品的系统和方法。 本文中的系统和方法可以在一个综合生物精炼厂中进行配置和使用。 综合生物精炼可以包括糖生产设备，例如糖厂，用于一种或多种生物产物例如丁醇的生产设备，以及任选地使用该系统和方法的乙醇生产设备。

公开(公告)号：US08527102B2

公开(公告)日：2013-09-03

申请号：US12827923

申请日：2010-06-30

申请人： Patrick D. Noll ,  James F. Bartee

发明人： Patrick D. Noll ,  James F. Bartee

IPC分类号： G06F19/00

CPC分类号： C12M21/12 ,  C12M23/58 ,  C12M41/18

摘要： According to various embodiments, a biofuel production system includes a plurality of parallel-operated fermenters, a cooling tower water system configured to supply cooling water to the plurality of parallel-operated fermenters, a chiller water system configured to supply chiller water to the plurality of parallel-operated fermenters, and a cooling system coupled to the plurality of parallel-operated fermenters, the cooling tower water system, and the chiller water system. The cooling system controls the flow rates of the cooling water and the chiller water to the plurality of parallel-operated fermenters based upon temperatures of fermentation products of the fermenters.

摘要翻译： 根据各种实施方案，生物燃料生产系统包括多个平行操作的发酵罐，冷却塔水系统，其构造成向多个平行操作的发酵罐供应冷却水;冷却水系统，其被配置为向多个 并联操作的发酵罐，以及耦合到多个平行操作的发酵罐，冷却塔水系统和冷却水系统的冷却系统。 冷却系统基于发酵罐的发酵产物的温度来控制冷却水和冷却器水对多个平行操作的发酵罐的流量。