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公开(公告)号：US20180236379A1
公开(公告)日：2018-08-23
申请号：US15752121
申请日：2016-08-12
发明人： Jonathan L. Belanger , Hua Yang , Edouard S.P. Bouvier , Mathew DeLano , Raymond P. Fisk , Hillary B. Hewitson , Wade P. Leveille , Kevin Daniel Wyndham
CPC分类号： B01D15/22 , B01D53/02 , B01D53/025 , B01D2253/1122 , B01L3/502753 , C12M21/18 , C12M23/20 , G01N30/6052 , G01N30/6073 , G01N30/6095 , G01N30/7266 , G01N2030/8831
摘要： Exemplary embodiments are directed to devices for separating a sample by chromatography, components of the devices, and methods for using the devices, and directed to devices and components for use with immobilized enzymatic reactors. A device includes a wall having a wetted surface exposed to a mobile phase including the sample during chromatographic separation. The wetted surface of the wall includes an alloy material including the following constituents: nickel, and cobalt and/or chromium where the alloy is limited in an amount of titanium to 1 wt %. A component includes a body having a wetted surface exposed to a mobile phase including the sample during chromatographic separation. The wetted surface of the body includes an alloy material including the following constituents: nickel, and cobalt and/or chromium where the alloy is limited in an amount of titanium to 1 wt %.
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公开(公告)号：US10017801B2
公开(公告)日：2018-07-10
申请号：US15596313
申请日：2017-05-16
申请人： XYLECO, INC.
IPC分类号： C12P19/02 , C12P19/14 , C12P7/10 , C13K1/02 , C13K13/00 , C12M1/40 , C12M1/02 , C12M1/00 , C12P7/14
CPC分类号： C12P19/02 , C12M21/18 , C12M27/00 , C12M29/06 , C12P7/10 , C12P7/14 , C12P19/14 , C12P2201/00 , C12P2203/00 , C13K1/02 , C13K13/002 , Y02E50/16 , Y02E50/17 , Y02E50/30
摘要： Methods of processing paper feedstocks are provided, as well as intermediates and products made using such methods. Certain types of paper feedstocks, in particular highly pigmented papers, and/or highly loaded papers such as paper that has been color printed, e.g., magazines, and high basis weight coated papers, e.g., magazine stock, are utilized to produce useful intermediates and products, such as energy, fuels, foods or materials.
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公开(公告)号：US20180171379A1
公开(公告)日：2018-06-21
申请号：US15884902
申请日：2018-01-31
发明人： Joomi Ahn , Moon Chul Jung , Kevin D. Wyndham
摘要： An immobilized enzymatic reactor can include a wall defining a chamber having an inlet and an outlet; a solid stationary phase covalently linked to an enzyme and disposed within the chamber; and a pressure modulator in fluid communication with the chamber and adapted to support continuous flow of a liquid sample comprising a polymer analyte through the inlet, over the solid stationary phase, and out of the outlet under a pressure between about 2,500 and 35,000 psi. In one example, the solid stationary phase includes inorganic/organic hybrid particles in an ultra performance liquid chromatography system, the enzyme is a protease, and the polymer analyte is a polypeptide. The immobilized enzymatic reactor can prepare an analyte for applications such as for hydrogen deuterium exchange mass spectrometry.
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公开(公告)号：US10000731B2
公开(公告)日：2018-06-19
申请号：US13597304
申请日：2012-08-29
申请人： Sobhi Basheer , Maisa Haj , Usama Mohsen , Doaa Shehadeh , Ahmad Hindawi , Emad Masoud , Ahmad Egbarieh , Ramez Masri
发明人： Sobhi Basheer , Maisa Haj , Usama Mohsen , Doaa Shehadeh , Ahmad Hindawi , Emad Masoud , Ahmad Egbarieh , Ramez Masri
摘要： Disclosed are an enzymatic batchwise or continuous process for the production of fatty acid alkyl esters for use in the biofuels, food and detergent industries and a system therefor. The process utilizes enzymes immobilized on a hydrophobic resin mixed with a fatty acid source and an alcohol or alcohol donor in the presence of an alkaline or mild alkaline aqueous buffer, or in the presence of water or aqueous solution. The production process for fatty acid alkyl esters is carried out by transesterification or esterification simultaneously or sequentially. The biocatalyst activity is maintained with no significant activity losses in multiple uses and also avoids the accumulation of glycerol and water by-products or other hydrophilic compounds on the biocatalyst.
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公开(公告)号：US20180002171A1
公开(公告)日：2018-01-04
申请号：US15604651
申请日：2017-05-25
申请人： Ghassem Amoabediny , Mahdi Pesaran
发明人： Ghassem Amoabediny , Mahdi Pesaran
CPC分类号： C12M29/00 , B01L2300/0896 , C12M1/40 , C12M21/18 , C12M23/16 , C12M23/58 , C12M25/02 , C12N11/12
摘要： A nano-bioreactor, and an enzymatic nano-bioreactor apparatus are disclosed. The enzymatic nano-bioreactor, comprises at least one enzyme, and a cellulose nano-fiber. The enzyme is any one of a urease, a glutamate dehydrogenase, and a glutamine synthetase configured to immobilize on the cellulose nano-fiber. The enzymatic nano-bioreactor apparatus comprises a plurality of input pumps, which is configured to introduce at least one input to a plurality of micro-bioreactors, where connected each other by a connector. The apparatus further comprises, at least one nano-bioreactor placed inside the micro-bioreactor, configured to receive the input, and an outlet configured to extrude a resultant output from the nano-bioreactor to a collector unit. The present also discloses a method for manipulating extracellular metabolic system using the said enzymatic nano-bioreactor apparatus.
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公开(公告)号：US20170298399A1
公开(公告)日：2017-10-19
申请号：US15488273
申请日：2017-04-14
IPC分类号： C12P17/06 , C12M1/40 , C07D311/80 , C07C227/16 , C12P13/04 , C12M1/34
CPC分类号： C12P17/06 , C07C69/16 , C07C69/708 , C07C213/08 , C07C219/04 , C07C227/16 , C07C229/12 , C07C271/44 , C07C271/52 , C07C2601/16 , C07D311/74 , C07D311/80 , C12M21/18 , C12M41/26 , C12M41/48 , C12P13/04 , C12Y121/03007 , C12Y121/03008
摘要： The present invention provides methods for producing cannabinoid prodrugs. Also described are pharmaceuticals acceptable compositions of the prodrugs and a system for the large-scale production of the prodrugs.
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公开(公告)号：US20170247649A1
公开(公告)日：2017-08-31
申请号：US15510278
申请日：2015-09-14
申请人： ALKYMAR AS
CPC分类号： C12M21/18 , B01F5/0647 , B01F5/065 , B01F5/0655 , B01F2215/0073 , B01F2215/0431 , B01F2215/0477 , B01F2215/0481 , B63B35/14 , C12M27/00 , C12M27/16 , C12M29/04 , C12M41/22 , C12P21/06
摘要： An enzymatic processing plant for continuous flow-based enzymatic processing of organic molecules, comprises an enzymatic processing area, wherein the enzymatic processing area comprises a turbulence-generating pipe with a repeatedly changing centre-line and/or a repeatedly changing cross-section, for generating turbulence to mix a reaction mixture and prevent sedimentation of particles as the reaction mixture is flowing through the turbulence-generating pipe, and wherein the enzymatic processing plant and the enzymatic processing area are arranged such that the reaction mixture is subjected to turbulence within the enzymatic processing area for a reaction time of 15 minutes or more.
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公开(公告)号：US20170226535A1
公开(公告)日：2017-08-10
申请号：US15267617
申请日：2016-09-16
发明人： Scott TUDMAN
CPC分类号： C12P3/00 , C01B32/324 , C01B32/336 , C01B32/342 , C01B32/366 , C01B32/382 , C01B32/39 , C01P2004/61 , C01P2006/80 , C02F1/283 , C10B53/02 , C12M21/18 , C12M41/12 , C12M47/10 , Y02E50/14
摘要： Provided are methods, systems, and compositions for producing activated carbon from lignin residues produced from cellulosic or lignocellulosic biomass after hydrolysis of saccharides. The activated carbon is low in ash and sulfur, high in oxygen content and iodine number.
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公开(公告)号：US20170159080A1
公开(公告)日：2017-06-08
申请号：US15441109
申请日：2017-02-23
CPC分类号： C12P7/26 , A01H6/28 , A61K31/352 , C12M21/18 , C12M41/30 , C12M41/48 , C12N9/0004 , C12N9/1029 , C12P7/04 , C12P7/22 , C12P7/42 , C12P7/62 , C12P17/06 , C12Y121/03007 , C12Y121/03008 , C12Y203/01206 , C12Y205/01102 , Y02A50/473
摘要： The present invention provides methods for producing cannabinoids and cannabinoid analogs as well as a system for producing these compounds. The inventive method is directed to contacting a compound according to Formula I or Formula II with a cannabinoid synthase. Also described is a system for producing cannabinoids and cannabinoid analogs by contacting a THCA synthase with a cannabinoid precursor and modifying at least one property of the reaction mixture to influence the quantity formed of a first cannabinoid relative to the quantity formed of a second cannabinoid.
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公开(公告)号：US20170145374A1
公开(公告)日：2017-05-25
申请号：US15422056
申请日：2017-02-01
发明人： Willem Heber Van Zyl , Josebus Maree Van Zyl , Thomas Michael Harms , Eugene Van Rensburg , Lee Rybick Lynd
摘要： The invention provides a method and system for controlling the conversion of crystalline insoluble cellulose to an organic product in a bioreactor containing crystalline insoluble cellulose and a culture medium. A processor of a computing device receives an input from a sensor in the bioreactor. The input may be a measurement of one or more of concentration, temperature, pH and pressure. The processor calculates conversion of cellulose using the input to provide a total calculated organic product in the bioreactor. The processor receives a further input from a sensor in the bioreactor of the total actual organic product and compares the total calculated organic product and the total actual organic product. The processor then transmits an instruction to an agitator associated with the bioreactor to control agitation of the content of the bioreactor if the total actual organic product is outside a predetermined range of the total calculated organic product.
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