公开(公告)号：US20200275879A1

公开(公告)日：2020-09-03

申请号：US16856477

申请日：2020-04-23

Applicant: CLEMSON UNIVERSITY RESEARCH FOUNDATION

Inventor： JEFFREY ANKER ,  CALEB BEHREND ,  JOHN DESJARDINS

IPC: A61B5/00 ,  G01L1/24 ,  G01L1/25 ,  A61B6/12 ,  A61B6/00 ,  A61B5/107 ,  A61B17/72 ,  A61B17/80 ,  G01L19/08

Abstract: Implantable sensors for determining bone health that can be utilized in conjunction with orthopedic implants are described. The sensors can include passive strain gauges or passive chemical sensors that can be read by radiographic imaging techniques. Sensors can be affixed to implantable support devices so as to non-invasively monitor the effect of load on the implant; for instance, to provide a quantitative assessment of when a fracture is sufficiently healed to allow safe weight-bearing upon the limb. Alternatively, sensors can monitor the health of a local implant area; for instance, to monitor the implant area of early stage infection or healing of a fusion procedure.

公开(公告)号：US10660754B2

公开(公告)日：2020-05-26

申请号：US16010889

申请日：2018-06-18

Applicant: Clemson University Research Foundation

Inventor： Leslie Sierad ,  Richard Pascal, III ,  Chris deBorde ,  Dan Simionescu ,  Agneta Simionescu

IPC: A61F2/24

Abstract: Tissue holders that can be used for gripping natural or synthetic heart valves are described. The tissue holder can include a clamping mechanism and a spring and can be self-adjusting with regard to pressure applied to the tissue gripped in the holder. The tissue holder can be removably attached to systems for processing the tissues and can provide completely hands-free processing of a tissue from development or excisement to implantation and/or completion of testing.

公开(公告)号：US20200095361A1

公开(公告)日：2020-03-26

申请号：US16512937

申请日：2019-07-16

Applicant: Clemson University Research Foundation

Inventor： Marek W. Urban

IPC: C08F293/00

Abstract: Provided is a copolymer exhibiting self-healing properties. The copolymer comprises first units comprising first pendant groups wherein the first pendant groups are alkyls having at least 1 to no more than 6 carbons. Second units comprising second pendant groups are alkyls having at least 2 to no more than 8 carbons. The first units and second units are in a molar ratio of 45/55 to 55/45 and the pendant groups form an inter-pendant space having a volume of at least 80 Ang.3 to no more than 140 Ang.3. The copolymer comprises no more than 3 adjacent first units and no more than 3 adjacent second units.

公开(公告)号：US10596909B2

公开(公告)日：2020-03-24

申请号：US15571739

申请日：2016-05-06

Applicant: The Regents of the University of Michigan ,  Clemson University Research Foundation

Inventor： Saemin Choi ,  Jason Benjamin Siegel ,  Seyed Yasha Parvini Oskoui ,  Ernesto G. Urdaneta

IPC: H02J7/00 ,  B60L11/00 ,  H02J7/14 ,  H02J7/34 ,  B60L1/00 ,  B60L50/40 ,  B60L58/22 ,  B60L58/20

Abstract: A system includes a first energy storage device, a second energy storage device coupled to the first energy storage device and charged via a charging current from the first energy storage device, a power controller having a processor, a memory coupled to the processor and on which charging current instructions are stored, and a converter coupled to the processor and directed via switch control signals from the processor, and an output terminal via which power is provided to a load of the system. The converter is disposed between the first energy storage device and the output terminal. The converter is disposed between the first and second energy storage devices and configured to control a level of the charging current in accordance with the switch control signals. The charging current instructions are executed by the processor to cause the processor to generate the switch control signals such that the level of the charging current is regulated.

公开(公告)号：US10441321B2

公开(公告)日：2019-10-15

申请号：US15374615

申请日：2016-12-09

Applicant: MUSC Foundation for Research Development ,  Clemson University Research Foundation

Inventor： Gregory J. Wright ,  Hai Yao ,  Richard H. Gross

IPC: A61B17/70

Abstract: Rib hook devices, systems, and methods of assembling and using the devices and systems are disclosed. The rib hook device includes a body with a first end and a second end and a rod attachment member coupled to and extending away from the second end of the body. The rib hook system includes at least one rib hook device, a first rod for engaging the at least one rib hook device, and at least one fastener for securing the first rod to the at least one rib hook device. Methods for assembling and using the rib hook devices and systems are also disclosed.

公开(公告)号：US20190269347A1

公开(公告)日：2019-09-05

申请号：US16328430

申请日：2017-08-28

Applicant: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT ,  CLEMSON UNIVERSITY RESEARCH FOUNDATION

Inventor： DeMore Nancy ,  Delphine Dean ,  Scott R. Slaney ,  Melissa McCullough ,  Cody Jordan ,  Joseph R. Wilson, III

IPC: A61B5/06 ,  A61B90/00

Abstract: Systems and methods for detecting metal clips inserted within a portion of a body of a patient are disclosed herein. In one embodiment, a clip detector assembly includes a detector having a ferrous member, a transmitting coil around the ferrous member and configured to induce a current in the metal clip, and a receiving coil around the ferrous member and configured to receive a magnetic field generated by the current induced in the metal clip. The assembly can further include a control circuit having a band-pass filter configured to pass electrical signals induced by the magnetic field from the receiving coil that are within at most 35 kHz of a resonance frequency of the metal clip. The assembly still further includes a user notification component configured to alert a user to a location of the metal clip.

公开(公告)号：US20190231930A1

公开(公告)日：2019-08-01

申请号：US16379121

申请日：2019-04-09

Applicant: CLEMSON UNIVERSITY RESEARCH FOUNDATION

Inventor： LESLIE SIERAD ,  ELIZA LAINE SHAW ,  GEORGE FERCANA ,  DAN SIMIONESCU

IPC: A61L27/36

CPC classification number: A61L27/3687 ,  A61F2/2415 ,  A61L27/3604 ,  A61L27/3625 ,  A61L27/3691 ,  A61L2430/20 ,  A61L2430/40

Abstract: Systems and methods that establish a pressure differential across a tissue wall to encourage complete decellularization of the wall are described. The methods can be utilized for decellularization of blood vessel tissue including heart valves and surrounding tissues. The methods and systems can essentially completely decellularize the treated tissue segments. Systems can be utilized to decellularize one or multiple tissue segments at a single time.

公开(公告)号：US20180354853A1

公开(公告)日：2018-12-13

申请号：US15990188

申请日：2018-05-25

Applicant: Clemson University Research Foundation

Inventor： Rhett C. SMITH ,  Andrew G. TENNYSON

IPC: C04B26/28 ,  C04B28/02 ,  C04B18/02 ,  C04B14/06

CPC classification number: C04B26/285 ,  C04B14/06 ,  C04B18/021 ,  C04B18/022 ,  C04B26/28 ,  C04B28/02 ,  C04B2103/0062 ,  C04B2111/00646 ,  C04B2111/0075

Abstract: In one aspect, composite polymeric composition and related materials are described herein employing waste products from the agricultural and energy industries. Such composite polymeric compositions and materials can repurpose agricultural and petroleum waste products for various applications including, but not limited to, building and/or infrastructure materials. In some embodiments, a composite polymeric composition described herein comprises polysaccharides, lignin or combinations thereof covalently cross-linked via linkages comprising sulfur.

公开(公告)号：US09693867B2

公开(公告)日：2017-07-04

申请号：US14730984

申请日：2015-06-04

Applicant: Clemson University Research Foundation ,  University of South Carolina ,  Kim John Chillag

Inventor： Eric Montgomery Lucas ,  John David DesJardins ,  Kim John Chillag ,  Frank Richard Voss

IPC: A61F2/38 ,  A61F2/30 ,  A61F2/40 ,  A61F2/32 ,  A61F2/42 ,  A61F2/48

CPC classification number: A61F2/3845 ,  A61F2/30 ,  A61F2/32 ,  A61F2/3804 ,  A61F2/3836 ,  A61F2/384 ,  A61F2/385 ,  A61F2/40 ,  A61F2/42 ,  A61F2/4202 ,  A61F2/4261 ,  A61F2002/30079 ,  A61F2002/30329 ,  A61F2002/30492 ,  A61F2002/30565 ,  A61F2002/30607 ,  A61F2002/30622 ,  A61F2002/30632 ,  A61F2002/30668 ,  A61F2002/3813 ,  A61F2002/482 ,  A61F2250/0006 ,  A61F2250/0008 ,  A61F2250/0073

Abstract: Total knee replacements for hinged knee implants include a tibial member, a femoral member, a hinge assembly having a laterally extending axle configured to hingedly attach the femoral member to the tibial member, and a lock mechanism in communication with the hinge assembly. The lock mechanism is configured to (i) lock the femoral member in alignment with the tibial member for a full extension or other defined stabile walking configuration to thereby allow an arthrodesis or stiff knee gait and (ii) unlock to allow the femoral and tibial members to pivot relative to each other for flexion or bending when not ambulating.

公开(公告)号：US20160287398A1

公开(公告)日：2016-10-06

申请号：US15184567

申请日：2016-06-16

Applicant: Kim John Chillag ,  Clemson University Research Foundation ,  University of South Carolina

Inventor： Eric Montgomery Lucas ,  John David DesJardins ,  Kim John Chillag ,  Frank Richard Voss

IPC: A61F2/38 ,  A61F2/40 ,  A61F2/42 ,  A61F2/32

CPC classification number: A61F2/3845 ,  A61F2/30 ,  A61F2/32 ,  A61F2/3804 ,  A61F2/3836 ,  A61F2/384 ,  A61F2/385 ,  A61F2/40 ,  A61F2/42 ,  A61F2/4202 ,  A61F2/4261 ,  A61F2002/30079 ,  A61F2002/30329 ,  A61F2002/30492 ,  A61F2002/30565 ,  A61F2002/30607 ,  A61F2002/30622 ,  A61F2002/30632 ,  A61F2002/30668 ,  A61F2002/3813 ,  A61F2002/482 ,  A61F2250/0006 ,  A61F2250/0008 ,  A61F2250/0073

Abstract: Total joint replacements for implants include a first member configured to attach to a first bone, a second member configured to reside in an adjacent second hone and a locking mechanism. The locking mechanism is configured to (i) lock the first and second members in alignment for full extension or other defined stabilized configuration and (ii) unlock to allow the first and second members to pivot relative to each other for flexion or bending.

Abstract translation: 用于植入物的总共关节置换包括构造成附接到第一骨骼的第一构件，被配置为驻留在相邻的第二磨牙中的第二构件和锁定机构。 锁定机构被配置为（i）将第一和第二构件锁定在对准以便完全延伸或其他限定的稳定构型，以及（ii）解锁以允许第一和第二构件相对于彼此枢转以弯曲或弯曲。