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71.发明授权
公开(公告)号：US5741518A
公开(公告)日：1998-04-21
申请号：US698658
申请日：1996-08-16
Applicant: Alain Ribier , Jean-Thierry Simonnet , Rose-Marie Handjani , Nadia Terren
Inventor： Alain Ribier , Jean-Thierry Simonnet , Rose-Marie Handjani , Nadia Terren
IPC: A61K8/14 , A61K8/39 , A61K8/49 , A61K8/60 , A61K8/70 , A61K8/86 , A61Q1/02 , A61Q19/00 , A61Q19/08 , A61K9/127
CPC classification number: A61Q19/08 , A61K8/14 , A61K8/39 , A61K8/4973 , A61K8/4993 , A61K8/60 , A61K8/70 , A61K8/86 , A61Q19/00 , B82Y5/00 , A61Q1/02 , A61Q19/007 , Y10T428/2984
Abstract: The vesicles are prepared from a lipid phase containing a mixture of nonionic amphiphilic lipids consisting of a mixture of esters of at least one polyol chosen from the group composed of polyethylene glycol containing from 1 to 60 ethylene oxide units, sorbitan, sorbitan bearing 2 to 60 ethylene oxide units, glycerol bearing 2 to 30 ethylene oxide units, polyglycerols containing 2 to 15 glycerol units, sucroses, and glucoses bearing 2 to 30 ethylene oxide units and of at least one fatty acid containing a saturated or unsaturated, linear or branched C.sub.5 -C.sub.17 alkyl chain, the number of alkyl chains per polyol group being between 1 and 10, the mixture being stabilized with ionic amphiphilic lipid or lipids chosen from the group composed of those which impart a pH of between 5.5 and 7.5 to the dispersion.
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72.发明授权Composition for combating ageing acting simultaneously on the surface layers and deep layers of the skin and use thereof 失效用于对抗老化的组合物同时作用于皮肤的表层和深层及其用途
公开(公告)号：US5629015A
公开(公告)日：1997-05-13
申请号：US366740
申请日：1994-12-30
Applicant: Alain Ribier , Jean-Thierry Simonnet , Florence Girerd , Francoise Gagnebien-Cabanne
Inventor： Alain Ribier , Jean-Thierry Simonnet , Florence Girerd , Francoise Gagnebien-Cabanne
IPC: A61K47/24 , A61K8/00 , A61K8/14 , A61K8/19 , A61K8/30 , A61K8/34 , A61K8/36 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/39 , A61K8/44 , A61K8/49 , A61K8/55 , A61K8/58 , A61K8/64 , A61K8/65 , A61K8/66 , A61K8/67 , A61K8/72 , A61K8/92 , A61K8/96 , A61K8/97 , A61K8/98 , A61K31/575 , A61K45/00 , A61Q19/00 , A61Q19/08 , A61K9/127 , A61K7/00
CPC classification number: A61Q19/08 , A61K8/14 , A61K8/4926 , Y10S514/844
Abstract: Compositions comprising a first dispersion of lipid vesicles which are capable of penetrating into the deep layers of the skin and which contain at least one active agent chosen from moisturizing agents, anti-free-radical agents, keratolytic agents, protides, enzymes, anti-elastase agents and anti-collagenase agents, and fatty acid derivatives, for treating these deep layers, and a second dispersion of lipid vesicles which are capable of penetrating into the surface layers of the skin and which contain at least one active agent chosen from keratolytic agents, tensioning agents, moisturizing agents, surface-restructuring agents and anti-free-radical agents, for treating these surface layers, are effective for combating ageing, acting simultaneously on the surface layers and deep layers of the skin.
Abstract translation: 组合物，其包含脂质囊泡的第一分散体，其能够渗透到皮肤的深层中并且含有至少一种活性剂，其选自保湿剂，抗自由基剂，角质分解剂，胶原酶，酶，抗弹性蛋白酶 用于治疗这些深层的药剂和抗胶原酶试剂和脂肪酸衍生物，以及能够渗入皮肤表层的脂质囊泡的第二分散体，并且含有至少一种选自角质分解剂的活性剂， 用于处理这些表面层的张力剂，保湿剂，表面重整剂和抗自由基剂对于抵抗老化，同时作用于皮肤的表层和深层是有效的。
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73.发明授权Cosmetic composition for the simultaneous treatment of the surface and deep layers of the skin, its use 失效化妆品组合物用于同时处理皮肤表层和深层，其用途
公开(公告)号：US5614215A
公开(公告)日：1997-03-25
申请号：US366723
申请日：1994-12-30
Applicant: Alain Ribier , Jean-Thierry Simonnet
Inventor： Alain Ribier , Jean-Thierry Simonnet
IPC: A61K9/06 , A61K8/00 , A61K8/02 , A61K8/03 , A61K8/11 , A61K8/14 , A61K8/23 , A61K8/34 , A61K8/36 , A61K8/37 , A61K8/41 , A61K8/44 , A61K8/49 , A61K8/63 , A61K8/64 , A61K8/65 , A61K8/67 , A61K8/72 , A61K8/86 , A61K8/896 , A61K8/92 , A61K8/97 , A61K8/98 , A61K9/127 , A61P17/06 , A61P17/10 , A61Q19/00 , A61Q19/02 , A61Q19/06 , A61Q19/08 , A61K7/00
CPC classification number: A61Q19/02 , A61K8/14 , A61Q19/00 , A61Q19/007 , A61Q19/06 , A61Q19/08 , Y10S514/844
Abstract: A composition comprising a first dispersion of lipid vesicles capable of entering the deep layers of the skin and containing at least one first active substance capable of treating these deep layers, and a second dispersion of lipid vesicles capable of entering the surface layers of the skin and containing at least one second active substance, different from the first active substance, capable of treating these surface layers is found effective for anti-age, anti-wrinkle, depigmenting, nutrient, slimming, hydrating, anti-ache, antimycotic, anti-dermic and anti-psoriatic treatment.
Abstract translation: 一种组合物，其包含能够进入皮肤深层并含有至少一种能够处理这些深层的第一活性物质的脂质囊泡的第一分散体和能够进入皮肤表层的脂质囊泡的第二分散体， 含有能够处理这些表面层的至少一种与第一活性物质不同的第二活性物质被发现可用于抗衰老，抗皱，脱色，营养，减肥，保湿，抗痛，抗真菌，抗皮肤 和抗牛皮癣治疗。
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74.发明授权
公开(公告)号：US5607692A
公开(公告)日：1997-03-04
申请号：US366739
申请日：1994-12-30
Applicant: Alain Ribier , Jean-Thierry Simonnet , Chantal Fanchon , Laurence Arnaud-Sebillotte , Evelyne Segot
Inventor： Alain Ribier , Jean-Thierry Simonnet , Chantal Fanchon , Laurence Arnaud-Sebillotte , Evelyne Segot
IPC: A61K9/127 , A61K8/00 , A61K8/11 , A61K8/14 , A61K8/19 , A61K8/20 , A61K8/30 , A61K8/33 , A61K8/34 , A61K8/35 , A61K8/36 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/42 , A61K8/44 , A61K8/49 , A61K8/55 , A61K8/60 , A61K8/64 , A61K8/67 , A61K8/72 , A61K8/73 , A61K8/86 , A61K8/92 , A61K8/97 , A61K8/98 , A61K45/00 , A61P43/00 , A61Q1/02 , A61Q19/00 , A61Q19/02 , A61K7/00
CPC classification number: A61K8/347 , A61K8/14 , A61K8/34 , A61K8/365 , A61K8/368 , A61K8/37 , A61K8/42 , A61K8/44 , A61K8/4926 , A61K8/4973 , A61K8/60 , A61K8/671 , A61K8/676 , A61K8/732 , A61K8/735 , A61K8/97 , A61K8/987 , A61Q19/02 , A61K2800/782 , Y10S514/844
Abstract: A composition comprising a first dispersion of lipid vesicles which are capable of penetrating into the deep layers of the skin and which contain at least one active agent selected from the group consisting of anti-pigmenting agents, depigmenting agents and tyrosinase inhibitors, for treating these deep layers, and a second dispersion of lipid vesicles which are capable of penetrating into the surface layers of the skin and which contain at least one active agent selected from the group consisting of keratolytic agents, moisturizing agents and protective agents, for treating these surface layers, is found effective for depigmenting skin.
Abstract translation: 一种组合物，其包含脂质囊泡的第一分散体，其能够渗透到皮肤的深层中并且含有至少一种选自抗着色剂，脱色剂和酪氨酸酶抑制剂的活性剂，用于治疗这些深层 层和脂质囊泡的第二分散体，其能够渗入皮肤的表层，并且含有至少一种活性剂，其选自角质分解剂，保湿剂和保护剂，用于处理这些表面层， 被发现有效脱色皮肤。
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75.发明授权Process for improving the therapeutic efficacy of fat-soluble corticosteroids and composition for carrying out this process 失效用于改善脂溶性角质酸的治疗效果的方法和用于实施本方法的组合物
公开(公告)号：US5190936A
公开(公告)日：1993-03-02
申请号：US536891
申请日：1990-06-13
Applicant: Jean-Pierre Laugier , Evelyne Segot , Francois Ringenbach , Jean-Thierry Simonnet , Philippe M. Touzan
Inventor： Jean-Pierre Laugier , Evelyne Segot , Francois Ringenbach , Jean-Thierry Simonnet , Philippe M. Touzan
CPC classification number: A61K31/57 , A61K9/1272
Abstract: The process consists in dissolving a corticosteroid in the lipid phase of nonionic amphiphilic lipid vesicles consisting of one or more lipid lamellae.Composition for carrying out the above process, in which the vesicles are dispersed in an aqueous phase D, have an average diameter of between 10 and 5,000 nm and contain as corticosteroids 17- and/or 21-mono- or -diesters of hydrocortisone, cortisone, prednisone, prednisolone or 6-methylprednisolone, the corticosteroids representing 0.5 to 2.5% by weight of the total lipids of the lamellae.
Abstract translation: 该过程包括将皮质类固醇溶解在由一种或多种脂质薄片组成的非离子两亲性脂质囊泡的脂质相中。 用于进行上述过程的组合物，其中囊泡分散在水相D中，其平均直径为10至5,000nm，并且含有作为皮质类固醇17和/或21-氢化可的松，可的松 ，泼尼松，泼尼松龙或6-甲基强的松龙，皮质类固醇占薄片总脂质重量的0.5〜2.5％。
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Patent Agency Ranking
公开(公告)号：US10925815B2
公开(公告)日：2021-02-23
申请号：US12866463
申请日：2009-02-11
Applicant: Jean-Thierry Simonnet , Florence L'Alloret , Lydie Bressy , Zohra Moujahed
Inventor： Jean-Thierry Simonnet , Florence L'Alloret , Lydie Bressy , Zohra Moujahed
Abstract: The present patent application relates to a composition for topical application in the form of an oil-in-water emulsion comprising an oily phase dispersed in an aqueous phase, characterized in that it comprises at least one noncrosslinked amphiphilic polymer, the globules of the said emulsion exhibiting a mean size ranging from 15 to 500 microns and the oily phase being present in an amount of less than 35% by weight, with respect to the total weight of the composition.
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公开(公告)号：US09364411B2
公开(公告)日：2016-06-14
申请号：US12648485
申请日：2009-12-29
Applicant: Jean-Thierry Simonnet , Julien Laboureau , Pascal Portes , Christophe Boulle
Inventor： Jean-Thierry Simonnet , Julien Laboureau , Pascal Portes , Christophe Boulle
Abstract: The present invention relates to the use, especially the cosmetic use, of at least one monosaccharide chosen from mannose, rhamnose and a mixture thereof, for reducing or preventing the signs of ageing of the skin or its integuments. The present invention also relates to a cosmetic composition and a device containing it.
Abstract translation: 本发明涉及至少一种选自甘露糖，鼠李糖及其混合物的单糖的用途，特别是化妆品用途，用于减少或预防皮肤或其皮肤老化的迹象。 本发明还涉及一种化妆品组合物和含有它的装置。
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公开(公告)号：US20150342863A1
公开(公告)日：2015-12-03
申请号：US14649441
申请日：2012-12-05
Applicant: CHUNHUA LI , Hy Si BUI , Jean-Thierry SIMONNET , L'OREAL
Inventor： Chunhua LI , Hy Si BUI , Jean-Thierry SIMONNET
CPC classification number: A61K8/87 , A61K8/8152 , A61K2800/43 , A61K2800/54 , A61K2800/81 , A61K2800/884 , A61Q3/02
Abstract: The invention relates to nail composition sets comprising at least one primer comprising compound(s) other than acrylic latex and at least one color coat comprising at least one acrylic latex and water.
Abstract translation: 本发明涉及指甲组合物组，其包含至少一种包含除丙烯酸胶乳之外的化合物的底漆和至少一种包含至少一种丙烯酸胶乳和水的着色涂层。
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公开(公告)号：US20150265524A1
公开(公告)日：2015-09-24
申请号：US14416438
申请日：2012-08-16
Applicant: Chunhua Li , Hy Si Bui , Jean-Thierry Simonnet , XianZhi Zhou
Inventor： Chunhua Li , Hy Si Bui , Jean-Thierry Simonnet , XianZhi Zhou
CPC classification number: A61K8/87 , A61K8/042 , A61K8/8117 , A61K8/8152 , A61K2800/30 , A61K2800/81 , A61K2800/884 , A61Q3/02
Abstract: The invention relates to nail composition sets comprising at least one primer and at least one color coat, wherein the primer comprises water and at least one adhesive compound and preferably further comprises at least one water-soluble film forming agent and/or at least one plasticizer.
Abstract translation: 本发明涉及包含至少一种底漆和至少一种彩色涂层的指甲组合物组合物，其中底漆包含水和至少一种粘合剂化合物，并且优选还包含至少一种水溶性成膜剂和/或至少一种增塑剂 。
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80.发明授权Synergistic antioxidant cosmetic compositions containing at least one of baicalin and taxifolin, at least one of caffeine and nicotinamide, at least one of vitamin C and resveratrol and ferulic acid 有权含有黄芩苷和紫杉醇，至少一种咖啡因和烟酰胺，至少一种维生素C和白藜芦醇和阿魏酸的协同抗氧化化妆品组合物公开(公告)号：US09072919B2
公开(公告)日：2015-07-07
申请号：US13650865
申请日：2012-10-12
Applicant: Zhi Pan , Jean-Thierry Simonnet , Ashleigh Murtaugh , Jamie Iannacone Spomer
Inventor： Zhi Pan , Jean-Thierry Simonnet , Ashleigh Murtaugh , Jamie Iannacone Spomer
IPC: A61Q19/00 , A61Q19/08 , A61K8/34 , A61K8/67 , A61K8/36 , A61K8/49 , A61K8/365 , A61K8/60 , A61K47/22 , A61K47/10
CPC classification number: A61Q19/08 , A61K8/347 , A61K8/36 , A61K8/365 , A61K8/494 , A61K8/498 , A61K8/602 , A61K8/675 , A61K8/676 , A61K47/10 , A61K47/22 , A61K2800/522
Abstract: The invention provides synergistic aqueous compositions comprising at least one flavonoid, and ferulic acid, and optionally one or more additional antioxidants, for cosmetic use.
Abstract translation: 本发明提供了包含至少一种类黄酮和阿魏酸以及任选的一种或多种另外的抗氧化剂用于化妆品用途的协同水性组合物。
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