摘要:
The invention relates to various substituted isoquinoline-1,3,4-trione, the synthetic method thereof and the use for treating neurodegenerative diseases, especially as the medicine for Alzheimer's disease, apoplexy and brain ischemic injuries.
摘要:
The current invention is based on the discovery that the Prol2Ala and VN102 single nucleotide polymorphisms in the PPARγ2 provides a method of determining a susceptibility to osteoporosis by detecting the presence of PPARγ of the alleles.
摘要:
A power supply structure includes a first circuit board, a second circuit board, a first connecting part and a second connecting part. The second circuit board is horizontally disposed above the first circuit board, a first connecting part electrically connected between the first circuit board and the second circuit board for transmitting signals of the first circuit board and second circuit and a second connecting part electrically connected between the first circuit board and the second circuit board for conducting currents of the first circuit board and the second circuit.
摘要:
Method and apparatus are provided for a semiconductor device including a junction and contact having a diffusion barrier to control silicidation of a silicon substrate. A dopant is applied in excess of an amount required to form a junction and the dopant chemically reacts with a metal to form a compound which serves as a barrier layer to prevent silidication in the substrate.
摘要:
Peak resolution in reversed-phase electrochromatography is improved in either of two alternative ways. The first is by a stepwise increase in the concentration of acetonitrile or other equivalent buffer constituent or modifier after the sample has been loaded, and the second is the inclusion of a surfactant in the mobile phase.
摘要:
Chromatographic media that demonstrate an artificially created recognition of any preselected molecular species with only can affinity-type adsorption are formed by polymerization from solutions of non-ionizable monomers with a quantity of the species contained in the solution, followed by removal of the species by conventional washing. The media are of particular utility and interest when used to achieve affinity binding of proteins. Uses of the media include chromatography and the general isolation and removal of the adsorbed species.
摘要:
A thin film transistor includes a thin film transistor body above a gate electrode. The thin film transistor body is hydrogenated to prevent the transistor body from apparently capturing and releasing electrons. The transistor body itself is coated with an upper and lower layer of silicon nitride to prevent the trapped hydrogen from migrating out of the transistor body over time. This is formed by depositing a layer of silicon dioxide, then a layer of silicon nitride over the gate electrode, followed by deposition of a polysilicon layer which is then etched to form the transistor body. This is hydrogenated after threshold adjustment implant and source/drain implant and subsequently coated with an upper sealing layer of silicon nitride. This enables the establishment of relatively high Ion/Ioff ratio and improves the reliability of the transistor.
摘要:
A semiconductor device having tungsten strapped gate electrodes and source/drain regions and a polysilicon resistor. The gate electrodes and the polysilicon resistors are all formed from the same layer of polysilicon by initially coating the deposited polysilicon layer with an insulating layer and subsequently a layer of phosphorus doped silicon glass. The electrodes and resistor areas are formed by selectively etching the silicon glass and the polysilicon. This leaves the electrode polysilicon and the resistor polysilicon coated with the phosphorous doped glass. Spacers are then provided along the electrode and the glass removed only from above the gate electrode polysilicon leaving the resistor coated with the phosphorus doped silicon glass and silicon nitride. Tungsten then can be selectively deposited upon the gate electrode and along adjacent source and drain regions. This takes advantage of the use of selectively deposited tungsten over gate electrodes and at the same time eliminates the need to deposit separate polysilicon layers for the resistors.
摘要:
A method is provided for evaluating the tension or laxity of the soft tissue surrounding a patient's knee joint. Based on this evaluation, a surgeon may determine a desired resection depth for a knee arthroplasty procedure that will achieve an appropriate spacing between adjacent, articulating components of the knee joint.
摘要:
The present invention relates to the use of a novel class of cancer stem cell pathway (CSCP) inhibitors; to methods of using such compounds to treat refractory, recurrent, or metastatic cancers; to methods of selective killing cancer cells by using such compounds with specific administration regimen; to methods of targeting cancer stem cells by inhibiting Stat3 pathway; to methods of using novel compounds in the treatment of conditions or disorders in a mammal related to aberrant Stat3 pathway activity; and to processes for preparing such compounds and intermediates thereof, and to the pharmaceutical composition of relevant compounds, and to the specific methods of administration of these compounds.