公开(公告)号：US20200268625A1

公开(公告)日：2020-08-27

申请号：US16871422

申请日：2020-05-11

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Yizhong Wang ,  Tiffany T. Ton ,  Melinda B. Gustafson ,  Jennifer Post ,  Paul R. Klaiber ,  Carola A. Carrera Vidal ,  Joel D. Oxman

IPC: A61K8/21 ,  A61K45/06 ,  A61K33/16 ,  A61K8/73 ,  A61K8/27 ,  A61C19/06 ,  A61K8/19 ,  A61K8/24 ,  A61K8/26 ,  A61K8/81 ,  A61Q11/00

Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.1 wt-% to 3.0 wt-% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; 0.025 wt-% to 1.75 wt-% of a multivalent cation salt; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.

公开(公告)号：US20200022896A1

公开(公告)日：2020-01-23

申请号：US16585341

申请日：2019-09-27

Applicant: 3M Innovative Properties Company

Inventor： Yizhong Wang ,  Joel D. Oxman ,  Tiffany Ton

IPC: A61K8/81 ,  A61Q11/00

Abstract: An oral composition is described. The oral composition can include a solvent having water and a cosolvent chosen from lower alkyl alcohols and acetone; a basic copolymer having basic acrylate monomeric units, basic methacrylate monomeric units, or a combination thereof; no less than 0.5 wt-% of an acid buffering or neutralizing agent; and optionally an active agent. The oral composition can include from about 6° to about 15° wt % of water, from about 30° to about 80° wt % of the cosolvent, and from about 25 to about 55° wt-% of the basic copolymer. The basic copolymer can be dissolved in the oral composition, the oral composition is capable of forming a film on a surface when contacted with an aqueous solution; and the wt-% of each component is based on the total weight of the composition.

公开(公告)号：US20190336259A1

公开(公告)日：2019-11-07

申请号：US16319415

申请日：2017-07-26

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Douglas L. Elmore ,  Korbinian Gerlach ,  Gregory A. Kobussen ,  Jack Wing Lai ,  Joel D. Oxman ,  Rudolf Schmid ,  Stefan K. Welker

IPC: A61C13/15 ,  C08F2/48

Abstract: Dental curing light systems capable of monitoring the degree of curing of polymerizable dental material. A monitoring light source delivers visible monitoring light at one or more different visible wavelengths and a visible light detector detects the monitoring light diffusely reflected by the polymerizable dental material. The monitoring light has a wavelength of maximum emission (λmax-mon) that does not effectively induce polymerization of the polymerizable dental material. Change in intensity of the monitoring light reflected from the polymerizable dental material is used to determine when a selected degree of curing is reached in the polymerizable dental material.

公开(公告)号：US20190282471A1

公开(公告)日：2019-09-19

申请号：US16302394

申请日：2017-05-22

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jie Yang ,  Richard P. Rusin ,  Petra L. Kohler Riedi ,  Joel D. Oxman ,  Jodi L. Connell

IPC: A61K8/25 ,  A61K8/41 ,  A61K8/42 ,  A61K8/44 ,  A61K8/24 ,  A61Q11/00

Abstract: Dental pastes are provided which include: (i) a compound of Formula (I), (ii) a compound of Formula (II) or a pharmaceutically acceptable salt thereof, and (iii) a dental abrasive.

公开(公告)号：US20170020800A1

公开(公告)日：2017-01-26

申请号：US15302275

申请日：2015-04-14

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Yizhong Wang ,  Joel D. Oxman

IPC: A61K8/81 ,  A61K8/22 ,  A61Q11/00 ,  A61K8/34

CPC classification number: A61K8/8152 ,  A61K8/22 ,  A61K8/34 ,  A61K8/345 ,  A61Q11/00 ,  A61Q11/02

Abstract: An oral composition is described. The oral composition can include a solvent comprising water and a cosolvent chosen from lower alkyl alcohols, acetone and a combination thereof, and an acidic copolymer comprising of carboxylic acid monomeric units. The acidic copolymers can be dissolved in the oral composition and the oral composition can form a film on a surface when contacted with an aqueous solution.

Abstract translation: 描述口服组合物。 口服组合物可以包括包含水和选自低级烷基醇，丙酮及其组合的共溶剂的溶剂和包含羧酸单体单元的酸性共聚物。 酸性共聚物可以溶解在口腔组合物中，口服组合物可以在与水溶液接触时在表面上形成膜。

公开(公告)号：US09458327B2

公开(公告)日：2016-10-04

申请号：US14243049

申请日：2014-04-02

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Kevin M. Lewandowski ,  Larry R. Krepski ,  Yizhong Wang ,  Joel D. Oxman ,  Peiwang Zhu ,  Brian N. Holmes ,  Thomas P. Klun ,  Bryan V. Hunt

IPC: C09D4/00 ,  C08F22/22 ,  C08F222/22 ,  C07C219/06 ,  C07C229/16 ,  C07C271/16 ,  C07D233/60 ,  C08F222/10

CPC classification number: C09D4/00 ,  C07C219/06 ,  C07C229/16 ,  C07C271/16 ,  C07D233/60 ,  C08F22/22 ,  C08F222/1006 ,  C08F222/22

Abstract: A multifunctional polymerizable ionic liquid is described comprising an anion and a cationic group having at least two ethylenically unsaturated polymerizable groups, each bonded to the cationic group via a divalent non-alkyl linking group. The multifunctional linking groups independently comprise a heteroatom such as oxygen or nitrogen. The linking groups may independently comprise one or more linkages such as an amide, urea, and more typically a urethane or ester linkage. The ethylenically unsaturated polymerizable groups are typically (meth)acrylate groups. Coatings and coated articles are also described.

Abstract translation: 描述了一种多功能可聚合离子液体，其包含具有至少两个烯属不饱和可聚合基团的阴离子和阳离子基团，各自通过二价非烷基连接基团与阳离子基团键合。 多官能连接基团独立地包含杂原子如氧或氮。 连接基团可以独立地包含一个或多个键，例如酰胺，脲，更典型的是氨基甲酸酯或酯键。 烯键式不饱和可聚合基团通常为（甲基）丙烯酸酯基团。 还描述了涂层和涂层制品。

公开(公告)号：US09414996B2

公开(公告)日：2016-08-16

申请号：US14437200

申请日：2013-10-31

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Guy D. Joly ,  Ahmed S. Abuelyaman ,  Ann R. Fornof ,  Bradley D. Craig ,  Larry R. Krepski ,  William H. Moser ,  Serkan Yurt ,  Joel D. Oxman ,  Afshin Falsafi

IPC: A61K6/083 ,  A61K6/00 ,  C09J133/14

CPC classification number: A61K6/083 ,  A61K6/0023 ,  A61K6/0088 ,  A61K6/0835 ,  C09J133/14 ,  C08L33/10

Abstract: A curable dental composition comprising an addition-fragmentation agent and a curable dental resin is disclosed.

Abstract translation: 公开了一种包含加成碎裂剂和可固化牙科用树脂的可固化牙科用组合物。

公开(公告)号：US20160220473A1

公开(公告)日：2016-08-04

申请号：US14917431

申请日：2014-09-10

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Yizhong Wang ,  Joel D. Oxman ,  Paul R. Klaiber ,  Jie J. Liu ,  Joanne A. Fitch ,  Tiffany T. Ton ,  Reinhold Hecht

IPC: A61K8/81 ,  A61Q11/00

CPC classification number: A61K8/8147 ,  A61K8/8152 ,  A61K2800/5424 ,  A61K2800/594 ,  A61K2800/92 ,  A61Q11/00

Abstract: An oral composition and a method of delivering an oral composition to a dental structure are described. The oral composition can include a solvent; an acidic copolymer having acidic acrylate monomeric units, acidic methacrylate monomeric units, or a combination thereof; a neutral copolymer having neutral acrylate monomeric units, neutral methacrylate monomeric units, or a combination thereof; and optionally an active agent. The acidic and neutral copolymers can be dissolved in the oral composition and the oral composition can form a film on a surface when contacted with an aqueous solution.

Abstract translation: 描述口腔组合物和将口腔组合物递送到牙科结构的方法。 口服组合物可包括溶剂; 具有酸性丙烯酸酯单体单元，酸式甲基丙烯酸酯单体单元或其组合的酸性共聚物; 具有中性丙烯酸酯单体单元，中性甲基丙烯酸酯单体单元或其组合的中性共聚物; 和任选的活性剂。 酸性和中性共聚物可以溶解在口腔组合物中，口服组合物可以在与水溶液接触时在表面上形成膜。

公开(公告)号：US20150238389A1

公开(公告)日：2015-08-27

申请号：US14707096

申请日：2015-05-08

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： William H. Moser ,  Guy D. Joly ,  Larry R. Krepski ,  Babu N. Gaddam ,  Ahmed S. Abuelyaman ,  Bradley D. Craig ,  Timothy D. Dunbar ,  Chuntao Cao ,  Joel D. Oxman ,  Afshin Falsafi ,  Hoa T. Bui

IPC: A61K6/083 ,  A61K6/00

CPC classification number: A61K6/083 ,  A61K6/0023 ,  A61K6/0029 ,  A61K6/005 ,  C08L33/10

Abstract: Dental compositions are described comprising an addition-fragmentation agent of the formula: wherein R1, R2 and R3 are each independently Zm-Q-, a (hetero)alkyl group or a (hetero)aryl group with the proviso that at least one of R1, R2 and R3 is Zm-Q-; Q is a linking group have a valence of m+1; Z is an ethylenically unsaturated polymerizable group; m is 1 to 6; each X1 is independently —O— or —NR4—, where R4 is H or C1-C4 alkyl; and n is 0 or 1. Also described are dental articles prepared from a dental composition comprising an addition-fragmentation agent and methods of treating a tooth surface.

Abstract translation: 描述了牙科组合物，其包含下式的加成断裂剂：其中R 1，R 2和R 3各自独立地为Zm-Q-，（杂）烷基或（杂）芳基，条件是R 1 ，R2和R3是Zm-Q-; Q是连接基团，其价态为m + 1; Z是烯属不饱和可聚合基团; m为1〜6; 每个X 1独立地是-O-或-NR 4 - ，其中R 4是H或C 1 -C 4烷基; 并且n为0或1.还描述了由包含加成碎裂剂的牙科组合物制备的牙科用品和治疗牙齿表面的方法。