公开(公告)号：US07786043B2

公开(公告)日：2010-08-31

申请号：US11632342

申请日：2005-07-22

申请人： Wassilios Grammenos ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Udo Hünger ,  Bernd Müller ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Ulrich Schöfl ,  Harald Köhle ,  Siegfried Strathmann ,  Maria Scherer ,  Reinhard Stierl ,  Jan Rether

发明人： Wassilios Grammenos ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Udo Hünger ,  Bernd Müller ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Ulrich Schöfl ,  Harald Köhle ,  Siegfried Strathmann ,  Maria Scherer ,  Reinhard Stierl ,  Jan Rether

IPC分类号： C07D239/74 ,  C07D239/70 ,  C07D401/04 ,  C07D403/04 ,  A01N43/54 ,  C07D213/16 ,  C07D213/84 ,  C07D213/53 ,  C07D213/61 ,  C07D213/26

CPC分类号： C07D401/04

摘要： The invention relates to 2-(pyridin-2-yl)-pyrimidine compounds of general formula (I) and their use for controlling pathogenic fungi and as plant protection products that, as an active constituent, contain compounds of this type: In general formula (I), k represents 0, 1, 2, 3; m represents 0, 1, 2, 3, 4 or 5; n represents 1, 2, 3, 4 or 5; R1, independent of one another, represents halogen, OH, CN, NO2, C1-C4 alkyl, C1-C4 alkyl halide, C1-C4 alkoxy, C1-C4 alkoxy halide, C2-C4 alkenyl, C2-C4 alkynyl, C3-C8 cycloalkyl, C1-C4 alkoxy-C1-C4 alkyl, amino, phenoxy, which is optionally substituted by halogen or C1-C4 alkyl, NHR, NR2, C(Ra)═N—ORb, S(═O)pA1 or C(═O)A2, or two radicals R1 bound to adjacent carbon atoms can, together, also represent a group —O-Alk-O—, wherein Alk represents a linear or branched C1-C4 alkylene, and 1, 2, 3 or 4 hydrogen atoms can also be replaced by halogen; R2 represents C1-C4 alkyl halide, C1-C4 alkoxy, C1-C4 alkoxy halide, hydroxy, halogen, CN or NO2; whereby R2 can also represent hydrogen or C1-C4 alkyl when at least one of the three following conditions is fulfilled: n represents 3, 4 or 5; k represents 1, 2 or 3; if m is not equal to 0, at least one of the radicals R1 represents a radical that differs from halogen, C1-C4 alkyl, C1-C4 alkoxy and C1-C4 alkyl halide, and; R3 represents C1-C4 alkyl.

摘要翻译： 本发明涉及通式（I）的2-（吡啶-2-基） - 嘧啶化合物及其用于控制​​致病真菌的用途，作为作为活性成分的植物保护产品含有这种化合物：通式 （I）中，k表示0,1,2,3; m表示0,1,2,3,4或5; n表示1,2,3,4或5; R 1彼此独立地表示卤素，OH，CN，NO 2，C 1 -C 4烷基，C 1 -C 4烷基卤，C 1 -C 4烷氧基，C 1 -C 4烷氧基卤化物，C 2 -C 4烯基，C 2 -C 4炔基， C8环烷基，C1-C4烷氧基-C1-C4烷基，氨基，苯氧基，其任选被卤素或C 1 -C 4烷基取代，NHR，NR 2，C（R a）= N-OR b，S（= O）p A1或C （ΟO）A2或与相邻碳原子结合的两个基团R1一起也可以代表基团-O-Alk-O-，其中Alk表示直链或支链C 1 -C 4亚烷基，和1,2,3或 4个氢原子也可以被卤素取代; R2代表C1-C4烷基卤，C1-C4烷氧基，C1-C4烷氧基卤化物，羟基，卤素，CN或NO2; 其中当满足以下三个条件中的至少一个时，R2还可以表示氢或C1-C4烷基：n表示3,4或5; k表示1,2或3; 如果m不等于0，则基团R1中的至少一个表示与卤素，C 1 -C 4烷基，C 1 -C 4烷氧基和C 1 -C 4烷基卤化物不同的基团， R3表示C1-C4烷基。

公开(公告)号：US07388018B2

公开(公告)日：2008-06-17

申请号：US10570893

申请日：2004-09-10

申请人： Wassilios Grammenos ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Jordi Tormo i Blasco ,  Thomas Grote ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Oliver Wagner ,  Norbert Götz ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Maria Scherer ,  Reinhard Stierl

发明人： Wassilios Grammenos ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Jordi Tormo i Blasco ,  Thomas Grote ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Oliver Wagner ,  Norbert Götz ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Maria Scherer ,  Reinhard Stierl

IPC分类号： A61K31/541 ,  A61K31/496 ,  C07D417/02 ,  C07D403/02

CPC分类号： C04B35/632 ,  C07D213/42 ,  C07D215/12 ,  C07D401/12 ,  C07D409/12

摘要： Sulfonamides of the formula I where the substituents are as follows: R1 is hydrogen, alkyl, alkoxy, alkenyl or alkynyl; and R2, R3, R4, R5 are hydrogen, halogen, alkyl, alkoxy or halomethyl; R2 and R3 together may also form a phenyl, cyclopentyl or cyclohexyl ring, it being possible for these rings to carry two groups R2, and R3, R2, R3, are hydrogen, halogen, alkyl, alkoxy or halomethyl; in case a), if R2, R3, R4 and R5 are hydrogen: X is phenyl substituted by a group —C(R6)═NOR7, where R6 is alkyl and R7 is alkyl, benzyl, alkenyl, haloalkyl, haloalkenyl, alkynyl or haloalkynyl; and in case b), if at least one of the groups R2, R3, R4 and R5 is not hydrogen: X is phenyl, naphthyl or a five- or six-membered saturated, or partially unsaturated or aromatic heterocycle which is attached via a carbon atom and contains one to four heteroatoms from the group consisting of O, N and S, where X may be substituted according to the description; Processes for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic harmful fungi.

摘要翻译： 式I的磺酰胺，其中取代基如下：R 1是氢，烷基，烷氧基，烯基或炔基; R 2，R 3，R 4，R 5是氢，卤素，烷基，烷氧基或卤代甲基 ; R 2和R 3一起也可以形成苯基，环戊基或环己基环，这些环可以携带两个基团R 2， R 3，R 2，R 3，R 3，R 3，R 3，R 3，R 3，R 3，R 3，R 3， 在a）情况下，如果R 2，R 3，R 4和R 5是氢：X是 由基团-C（R 6） - NOR 7取代的苯基，其中R 6为烷基，R 7为H 烷基，苄基，烯基，卤代烷基，卤代烯基，炔基或卤代炔基; 并且在情况b）中，如果R 2，R 3，R 4和R 5中的至少一个， SUP>不是氢：X是苯基，萘基或五或六元饱和或部分不饱和或芳族杂环，其通过碳原子连接并含有一至四个由O，N和S组成的组的杂原子 ，其中X可以根据描述被替代; 制备这些化合物的方法，包含它们的组合物及其用于控制​​植物病原性有害真菌的用途。

公开(公告)号：US09487519B2

公开(公告)日：2016-11-08

申请号：US10589953

申请日：2005-03-08

申请人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Oliver Wagner ,  Matthias Niedenbrück ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Reinhard Stierl

发明人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Oliver Wagner ,  Matthias Niedenbrück ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Reinhard Stierl

IPC分类号： C07D487/04

CPC分类号： C07D487/04

摘要： 5,6-Dialkyl-7-aminotriazolopyrimidines of the formula I in which the substituents are as defined below: R1 is alkyl or alkoxyalkyl, where the aliphatic groups may be substituted as defined in the description; R2 is CHR3CH3, cyclopropyl, CH═CH2 or CH2CH═CH2; R3 is hydrogen, CH3 or CH2CH3; processes for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic harmful fungi.

公开(公告)号：US20100286175A1

公开(公告)日：2010-11-11

申请号：US12840392

申请日：2010-07-21

申请人： Wassilios Grammenos ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Udo Hünger ,  Bernd Müller ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Ulrich Schöfl ,  Harald Köhle ,  Siegfried Strathmann ,  Maria Scherer ,  Reinhard Stierl ,  Jan Rether

发明人： Wassilios Grammenos ,  Thomas Grote ,  Carsten Blettner ,  Markus Gewehr ,  Udo Hünger ,  Bernd Müller ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Ulrich Schöfl ,  Harald Köhle ,  Siegfried Strathmann ,  Maria Scherer ,  Reinhard Stierl ,  Jan Rether

IPC分类号： A01N43/54 ,  C07D401/04 ,  A01P3/00

CPC分类号： C07D401/04

摘要： The invention relates to 2-(pyridin-2-yl)-pyrimidine compounds of general formula (I) and their use for controlling pathogenic fungi and as plant protection products that, as an active constituent, contain compounds of this type: In general formula (I), k represents 0, 1, 2, 3; m represents 0, 1, 2, 3, 4 or 5; n represents 1, 2, 3, 4 or 5; R1, independent of one another, represents halogen, OH, CN, NO2, C1-C4 alkyl, C1-C4 alkyl halide, C1-C4 alkoxy, C1-C4 alkoxy halide, C2-C4 alkenyl, C2-C4 alkynyl, C3-C8 cycloalkyl, C1-C4 alkoxy-C1-C4 alkyl, amino, phenoxy, which is optionally substituted by halogen or C1-C4 alkyl, NHR, NR2, C(Ra)═N—ORb, S(═O)pA1 or C(═O)A2, or two radicals R1 bound to adjacent carbon atoms can, together, also represent a group —O-Alk-O—, wherein Alk represents a linear or branched C1-C4 alkylene, and 1, 2, 3 or 4 hydrogen atoms can also be replaced by halogen; R2 represents C1-C4 alkyl halide, C1-C4 alkoxy, C1-C4 alkoxy halide, hydroxy, halogen, CN or NO2; whereby R2 can also represent hydrogen or C1-C4 alkyl when at least one of the three following conditions is fulfilled: n represents 3, 4 or 5; k represents 1, 2 or 3; if m is not equal to 0, at least one of the radicals R1 represents a radical that differs from halogen, C1-C4 alkyl, C1-C4 alkoxy and C1-C4 alkyl halide, and; R3 represents C1-C4 alkyl.

摘要翻译： 本发明涉及通式（I）的2-（吡啶-2-基） - 嘧啶化合物及其用于控制​​致病真菌的用途，作为作为活性成分的植物保护产品含有这种化合物：通式 （I）中，k表示0,1,2,3; m表示0,1,2,3,4或5; n表示1,2,3,4或5; R 1彼此独立地表示卤素，OH，CN，NO 2，C 1 -C 4烷基，C 1 -C 4烷基卤，C 1 -C 4烷氧基，C 1 -C 4烷氧基卤化物，C 2 -C 4烯基，C 2 -C 4炔基， C8环烷基，C1-C4烷氧基-C1-C4烷基，氨基，苯氧基，其任选被卤素或C 1 -C 4烷基取代，NHR，NR 2，C（R a）= N-OR b，S（= O）p A1或C （ΟO）A2或与相邻碳原子结合的两个基团R1一起也可以代表基团-O-Alk-O-，其中Alk表示直链或支链C 1 -C 4亚烷基，和1,2,3或 4个氢原子也可以被卤素取代; R2代表C1-C4烷基卤，C1-C4烷氧基，C1-C4烷氧基卤化物，羟基，卤素，CN或NO2; 其中当满足以下三个条件中的至少一个时，R2还可以表示氢或C1-C4烷基：n表示3,4或5; k表示1,2或3; 如果m不等于0，则基团R1中的至少一个表示与卤素，C 1 -C 4烷基，C 1 -C 4烷氧基和C 1 -C 4烷基卤化物不同的基团， R3表示C1-C4烷基。

公开(公告)号：US07820647B2

公开(公告)日：2010-10-26

申请号：US11596891

申请日：2005-05-17

申请人： Anja Schwögler ,  Frank Schieweck ,  Joachim Rheinheimer ,  Markus Gewehr ,  Bernd Müller ,  Thomas Grote ,  Wassilios Grammenos ,  Udo Hünger ,  Carsten Blettner ,  Peter Schäfer ,  Oliver Wagner ,  Reinhard Stierl ,  Ulrich Schöfl ,  Siegfried Strathmann ,  Maria Scherer

发明人： Anja Schwögler ,  Frank Schieweck ,  Joachim Rheinheimer ,  Markus Gewehr ,  Bernd Müller ,  Thomas Grote ,  Wassilios Grammenos ,  Udo Hünger ,  Carsten Blettner ,  Peter Schäfer ,  Oliver Wagner ,  Reinhard Stierl ,  Ulrich Schöfl ,  Siegfried Strathmann ,  Maria Scherer

IPC分类号： C07D239/48 ,  C07D403/04 ,  A01N43/54 ,  A01N43/58 ,  A01N43/34 ,  A01P3/00

CPC分类号： C07D401/04 ,  C07D403/04

摘要： The invention relates to 2-substituted pyrimidines of the formula I in which the index n and the substituents L and R1 to R3 are as defined in the description and X is a group —CH—Ra, —N—Rb—, —O— or —S—; Ra may be hydrogen, halogen, C1-C6-alkyl, C1-C6-alkoxy, cyano or C1-C6-alkoxycarbonyl; Rb is hydrogen, C1-C6-alkyl or C3-C6-cycloalkyl; T is a group —CH—Ra—; p is an integer from 1 to 4; Y is a group —CH—Ra— or —N—Rb—, o is 0 or 1; Z is O, S or a group N(Rc) Rc is hydrogen, C1-C6-alkyl or C1-C6-alkoxy, and to processes for their preparation, to pesticidal compositions comprising them and to their use as pesticides.

摘要翻译： 本发明涉及式I的2-取代嘧啶，其中指数n和取代基L和R1至R3如说明书中所定义，X为基团-CH-Ra，-N-Rb-，-O- 或-S-; R a可以是氢，卤素，C 1 -C 6 - 烷基，C 1 -C 6 - 烷氧基，氰基或C 1 -C 6 - 烷氧基羰基; R b是氢，C 1 -C 6 - 烷基或C 3 -C 6 - 环烷基; T是基团-CH-R a; p是1至4的整数; Y是基团-CH-R a或-N-R b - ，o是0或1; Z是O，S或基团N（R c）R c是氢，C 1 -C 6烷基或C 1 -C 6 - 烷氧基，并且其制备方法，包含它们的杀虫组合物和它们作为农药的用途。

公开(公告)号：US07488732B2

公开(公告)日：2009-02-10

申请号：US10549936

申请日：2004-03-30

申请人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Oliver Wagner ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Reinhard Stierl

发明人： Jordi Tormo i Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Oliver Wagner ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Reinhard Stierl

IPC分类号： C07D239/28 ,  C07D239/34 ,  C07D239/42 ,  C07D239/46 ,  A01N43/54

CPC分类号： A01N43/54 ,  C07D239/28 ,  C07D239/30

摘要： 2-Substituted pyrimidines of the formula I in which the index n and the substituents L, Ra, Rb, Rc, Rz, Ru, Rv, A′, A″ and A′″ are as defined in the description and: R1 is C3-C10-alkyl, C3-C10-alkenyl, C3-C10-alkynyl, C3-C12-cycloalkyl, C3-C10-cycloalkenyl or a five- to ten-membered saturated, partially unsaturated or aromatic heterocycle which is attached via carbon and contains one to four heteroatoms from the group consisting of O, N and S, R2 is halogen, cyano, C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkynyl, C1-C4-alkoxy, C3-C4-alkenyloxy or C3-C4-alkynyloxy, where the alkyl, alkenyl and alkynyl radicals of R2 may be substituted by halogen, cyano, nitro, C1-C2-alkoxy or C1-C4-alkoxycarbonyl, and R3 is cyano, CO2Ra, C(═O)NRzRb, C(═O)—N—ORb, C(═S)—NRaRb, C(═NORa)NRzRb, C(═NRa)NRzRb, C(═O)NRa—NRzRb, C(═N—NRzRc)NRaRb, C(═O)Ra, C(═NORb)Ra, C(═N—NRzRb)Ra, CRaRb—ORz, CRaRb—NRzRc, ON(═CRaRb), O—C(═O)Ra, NRaRb′, NRa(C(═O)Rb), NRa(C(═O)ORb), NRa(C(═O)—NRzRb), NRa(C(═NRc)Rb), NRa(N═CRcRb), NRa—NRzRb, NRz—ORa, NRa(C(═NRc)—NRzRb), NRa(C(═NORc)Rb), processes for preparing these compounds, compositions comprising these compounds and their pesticidal use are described.

摘要翻译： 其中指数n和取代基L，Ra，Rb，Rc，Rz，Ru，Rv，A'，A“和A”'如说明书中所定义的式I的2-取代的嘧啶：R1 C 3 -C 10 - 烷基，C 3 -C 10 - 烯基，C 3 -C 10 - 炔基，C 3 -C 12 - 环烷基，C 3 -C 10 - 环烯基或五至十元饱和的部分不饱和或芳族杂环，其通过碳 并且含有一至四个由O，N和S组成的组的杂原子，R2是卤素，氰基，C1-C4-烷基，C2-C4-烯基，C2-C4-炔基，C1-C4-烷氧基，C3-C4 - 烯氧基或C 3 -C 4 - 炔氧基，其中R 2的烷基，烯基和炔基可以被卤素，氰基，硝基，C 1 -C 2 - 烷氧基或C 1 -C 4 - 烷氧基羰基取代，并且R 3是氰基，CO 2 R a，C（ -O）NR z R b，C（-O）-N-OR b，C（-S）-NR a R b，C（-NOR a）NR z R b，C（-NR a）NR z R b，C（O）NR a -NR b R b，C -NRaRb，C（-O）Ra，C（-NORb）Ra，C（-N-NRzRb）Ra，CRaRb-ORz，CRaRb-NRzRc，ON（-CRaRb），OC（-O）Ra，NRaRb ，NR a（C（-O）R b），NR a（C（-O）R b），NR a（C（-O）OR b） NRa-N RzRb，NRz-ORa，NRa（C（-NRc）-NRzRb），NRa（C（-NORc）Rb），制备这些化合物的方法，包含这些化合物的组合物及其杀虫剂用途。

公开(公告)号：US07375108B2

公开(公告)日：2008-05-20

申请号：US10564013

申请日：2004-07-15

申请人： Anja Schwögler ,  Markus Gewehr ,  Bernd Müller ,  Thomas Grote ,  Wassilios Grammenos ,  Jordi Tormo i Blasco ,  Andreas Gypser ,  Joachim Rheinheimer ,  Carsten Blettner ,  Peter Schäfer ,  Frank Schieweck ,  Oliver Wagner ,  Reinhard Stierl ,  Ulrich Schöfl ,  Siegfried Strathmann ,  Maria Scherer

发明人： Anja Schwögler ,  Markus Gewehr ,  Bernd Müller ,  Thomas Grote ,  Wassilios Grammenos ,  Jordi Tormo i Blasco ,  Andreas Gypser ,  Joachim Rheinheimer ,  Carsten Blettner ,  Peter Schäfer ,  Frank Schieweck ,  Oliver Wagner ,  Reinhard Stierl ,  Ulrich Schöfl ,  Siegfried Strathmann ,  Maria Scherer

IPC分类号： C07D239/42 ,  A01N43/54

CPC分类号： C07D239/42

摘要： The invention relates to 2-substituted pyrimidines of the formula I in which the index n and the substituents R1 to R3 and L are as defined in the description and R4 corresponds to one of the formulae in which Ra, X and Rb are as defined in the description; and also to processes for preparing these compounds, to pesticidal compositions comprising these compounds and to their use as pesticides.

摘要翻译： 本发明涉及式I的2-取代嘧啶，其中指数n和取代基R 1至R 3和L如说明书中所定义， SUP> 4 对应于其中R a，S，X和R b的定义之一如说明书中所定义; 以及制备这些化合物的方法，包括这些化合物的农药组合物及其作为农药的用途。

公开(公告)号：US20060211711A1

公开(公告)日：2006-09-21

申请号：US10550571

申请日：2004-03-30

申请人： Jordi Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Reinhard Stierl

发明人： Jordi Blasco ,  Carsten Blettner ,  Bernd Müller ,  Markus Gewehr ,  Wassilios Grammenos ,  Thomas Grote ,  Andreas Gypser ,  Joachim Rheinheimer ,  Peter Schäfer ,  Frank Schieweck ,  Anja Schwögler ,  Maria Scherer ,  Siegfried Strathmann ,  Ulrich Schöfl ,  Reinhard Stierl

IPC分类号： A61K31/519 ,  C07D487/04 ,  A01N43/90

CPC分类号： C07D487/04 ,  A01N43/90

摘要： 7-alkinylamino-triazolopyrimidins of formula (I), wherein the substituents have the following meanings: L=halogen, alkyl, halogenalkyl, alkoxy, amino, NHR, NR2, cyano, S(O)nA1 or C(O)A2; R=alkyl or alkylcarbonyl, A1=hydrogen, hydroxy, alkyl, alkylamino or aialkylamino; n=0, 1 or 2; A2=alkenyl, alkoxy, halogenalkoxy or one of the groups cited in A1; m=1, 2, 3, 4 or 5, whereby at least one group L is present in an ortho-position to the bond with the triazolopyrimidine skeleton; X=halogen, cyano, alkyl, halogenalkyl or alkoxy; R1=hydrogen or alkyl; R2=alkinyl which can be unsubstituted or substituted according to the description. The invention also relates to methods for the production of said compounds, agents containing said compounds and the use thereof to combat harmful phytopathogenic fungi.

摘要翻译： 式（I）的7-烷基氨基 - 三唑并嘧啶类，其中取代基具有以下含义：L =卤素，烷基，卤代烷基，烷氧基，氨基，NHR，NR 2，氰基，S（O） 或者C（O）A 2 O 2。 R =烷基或烷基羰基，A 1〜H 2，羟基，烷基，烷基氨基或亚烷基氨基; n = 0,1或2; 链烯基，烷氧基，卤代烷氧基或A 1中引用的基团之一; m = 1,2,3,4或5，其中至少一个基团L存在于与三唑并嘧啶骨架的键的邻位; X =卤素，氰基，烷基，卤代烷基或烷氧基; R 1 =氢或烷基; R 2 =炔基，其可以是未取代的或根据描述取代的。 本发明还涉及生产所述化合物的方法，含有所述化合物的试剂及其用于对抗有害植物病原真菌的用途。

公开(公告)号：US20070149551A1

公开(公告)日：2007-06-28

申请号：US11677862

申请日：2007-02-22

申请人： Andreas GYPSER ,  Thomas Grote ,  Anja Schwogler ,  Joachim Rheiheimer ,  Frank Schieweck ,  Jordi Blasco ,  Ingo Rose ,  Peter Schafer ,  Markus Gewehr ,  Wassilios Grammenos ,  Bernd Muller ,  Eberhard Ammernann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

发明人： Andreas GYPSER ,  Thomas Grote ,  Anja Schwogler ,  Joachim Rheiheimer ,  Frank Schieweck ,  Jordi Blasco ,  Ingo Rose ,  Peter Schafer ,  Markus Gewehr ,  Wassilios Grammenos ,  Bernd Muller ,  Eberhard Ammernann ,  Siegfried Strathmann ,  Gisela Lorenz ,  Reinhard Stierl

IPC分类号： A61K31/506 ,  C07D403/02

CPC分类号： C07D239/42 ,  C07D239/47 ,  C07D239/48 ,  C07D239/52 ,  C07D403/12

摘要： 5-Phenylpyrimidines of the formula I in which the substituents and the index are as defined below: R1,R2 are hydrogen, alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkenyl, haloalkenyl, alkynyl or haloalkynyl, and R1 and R2 together with the nitrogen atom to which they are attached may also form a saturated or unsaturated ring which may be interrupted by an ether, thio, sulfoxyl or sulfonyl group and may be substituted by one to four groups Ra and/or Rb; R3 is hydrogen, halogen, cyano, alkyl, haloalkyl, alkoxy, haloalkoxy or alkenyloxy; R4 is hydrogen, halogen, cyano, hydroxyl, mercapto, azido, alkyl, alkenyl, alkynyl, haloalkyl, alkoxy, alkenyloxy, alkynyloxy, haloalkoxy, alkylthio, alkenylthio, alkynylthio, haloalkylthio, —ON═CRNaRb, —CRc═NORa, —NRcN═CRaRb, —NRaRb, —NRcNRaRb, —NORa, —NRcC (═NRc′)NRaRb, —NRcC(═O)NRaRb, —NRaC(═O)Rc, —NRaC(═NORc)Rc′, —OC (═O)Rc, —C(═NORc)NRaRb, —CRc(═NNRaRb), —C (═O)NRaRb or —C(═O) Rc; in which Ra, Rb and Rc are as defined in the description; X is halogen, alkyl, alkoxy or haloalkyl; and m is an integer from 1 to 5; processes for preparing these compounds, compositions comprising them and their use for controlling harmful fungi are described.

公开(公告)号：US20080176744A1

公开(公告)日：2008-07-24

申请号：US11885822

申请日：2006-03-08

申请人： Anja Schwogler ,  Joachim Rheinheimer ,  Wassilios Grammenos ,  Thomas Grote ,  Udo Hunger ,  Bernd Muller ,  Peter Schafer ,  Frank Schieweck

发明人： Anja Schwogler ,  Joachim Rheinheimer ,  Wassilios Grammenos ,  Thomas Grote ,  Udo Hunger ,  Bernd Muller ,  Peter Schafer ,  Frank Schieweck

IPC分类号： A01N43/54 ,  C07D239/42 ,  A01C1/06

CPC分类号： A01N43/54 ,  A01N43/56 ,  A01N43/653 ,  A01N43/84 ,  C07D239/42 ,  C07D239/47 ,  C07D239/48 ,  C07D401/04 ,  C07D403/04 ,  C07D405/12

摘要： The invention relates to the use of 4-aminopyrimidines of formula (I), in which R1═H, halogen, cyano, alkyl, alkylhalide, alkenyl, alkinyl, cycloalkyl, alkoxy, alkoxyalkyl, benzyloxyalkyl, alkoxyalkenyl or alkoxyalkinyl, R2═H, halogen, cyano, alkyl, alkylhalide, alkenyl, alkinyl, cycloalkyl, alkoxy, alkoxyalkyl and alkylthioalkyl, whereby the hydrocarbon chain in R1 and/or R2 can be substituted as given in the description, R1 and R2 can form, together with the carbon atom to which they are bonded, a 5-7-membered ring which can contain one to three same or different heteroatoms selected from the group O, N or S, R3═H, halogen, cyano, hydroxy, mercapto, azido, alkyl, alkenyl, alkinyl, alkylhalide, —O-D, —S(O)m-D, ON═CRaRb, CRc═NORa, NRcN═CRaRb, NRaRb, NRcNRaRb, NORa, NRcC(═NRc)NRaRb, NRcC(═O)NRaRb, NRaCN, —NRaC(═O)Rc, NRaC(═NORc)Rc′, OC(═O)Ra, C(═NORc)NRaRb, CRc(═NNRaRb), C(═O)NRaRb, C(═O)Ra, CO2Ra, C(═O)NRzRb, C(═O)—N—ORb, C(═S)—NRzRb, C(═O)NRa—NRzRb, C(═N—NRzRc)NRaRb, C(═NORb)Ra, C(═N—NRzRb)Ra, CRaRb—ORz, CRaRb—NRzRc, ON(═CRaRb), NRa(C(═O)Rb), NRa(C(═O)ORb), C(═NRa)NRzRb, C(═0)—NRzRb) NRa(C(═O)—NRzRb), NRa(C(═NRc)Rb), NRa(N═CRcRb), NRa—NRzRb, —NRz—ORa, NRa(C(═NRc)—NRzRb), NRa(C(═NORc)Rb) D=alkyl, alkenyl, alkinyl, alkylhalide, cycloalkyl, five- or six-membered saturated, partly-unsaturated or aromatic mono- or bicyclic heterocycles, containing one to four heteroatoms from the group O, N or S, one of the groups G1 or G2, whereby m, x, Ra, Rb, Rc, Rd, Re, Rz, Y, Z are as defined in the description and the aliphatic, alicyclic or aromatic groups R3, Ra, Rb, Rc, Rd or Re can be substituted as given in the description for the prevention of fungal pests, novel 4-aminopyridines, method for production of said compounds and agents comprising the same.