公开(公告)号：US20080214871A1

公开(公告)日：2008-09-04

申请号：US11814390

申请日：2006-01-19

申请人： Martin Ernst ,  Thilo Hahn ,  Kirsten Wenz ,  Randolf Hugo ,  Johann-Peter Melder

发明人： Martin Ernst ,  Thilo Hahn ,  Kirsten Wenz ,  Randolf Hugo ,  Johann-Peter Melder

IPC分类号： C07C211/27

CPC分类号： C07C209/48 ,  C07C211/27

摘要： A process for preparing a xylylenediamine by heterogeneously catalyzed hydrogenation of a phthalonitrile, wherein the hydrogenation is carried out in the presence of a cobalt skeletal catalyst, of an alkali metal hydroxide and of an alcohol and/or ether as the solvent, at an absolute pressure in the range from 1 to 100 bar and a temperature in the range from 40 to 150° C.

摘要翻译： 通过邻苯二甲腈的非均相催化氢化制备苯二甲胺的方法，其中氢化是在钴骨架催化剂存在下，碱金属氢氧化物和醇和/或醚作为溶剂在绝对压力下进行的 在1至100巴的范围内，温度在40至150℃的范围内。

公开(公告)号：US20080154061A1

公开(公告)日：2008-06-26

申请号：US11816878

申请日：2006-02-23

申请人： Martin Ernst ,  Kirsten Wenz ,  Randolf Hugo ,  Johann-Peter Melder ,  Thilo Hahn

发明人： Martin Ernst ,  Kirsten Wenz ,  Randolf Hugo ,  Johann-Peter Melder ,  Thilo Hahn

IPC分类号： C07C211/07

CPC分类号： C07C209/48 ,  C07C211/27

摘要： A process for preparing a xylylenediamine by heterogeneously catalyzed hydrogenation of a phthalonitrile, wherein the hydrogenation is carried out in the presence of a nickel catalyst, of water, of an alkali metal hydroxide and of an ether as a solvent, at an absolute pressure in the range from 1 to 100 bar, at a temperature in the range from 40 to 150° C. and without addition of ammonia.

摘要翻译： 通过邻苯二甲腈的非均相催化氢化制备苯二甲胺的方法，其中氢化在镍催化剂存在下，水，碱金属氢氧化物和作为溶剂的醚作为溶剂在绝对压力下进行 范围为1至100巴，温度范围为40至150℃，不加氨。

公开(公告)号：US20080306305A1

公开(公告)日：2008-12-11

申请号：US12097470

申请日：2006-12-05

申请人： Thilo Hahn ,  Martin Ernst ,  Johann-Peter Melder

发明人： Thilo Hahn ,  Martin Ernst ,  Johann-Peter Melder

IPC分类号： C07C209/00 ,  B01J25/00 ,  B01J25/02

CPC分类号： C07C209/48 ,  B01J23/78 ,  B01J25/02 ,  B01J27/232 ,  C07C211/12

摘要： A process for hydrogenating oligonitriles which have at least two nitrile groups in the presence of a catalyst which, before commencement of the hydrogenation, is pretreated by contacting with a compound A which is selected from alkali metal carbonates, alkaline earth metal carbonates, ammonium carbonate, alkali metal hydrogencarbonates, alkaline earth metal hydrogencarbonates, ammonium hydrogencarbonate, alkaline earth metal oxocarbonates, alkali metal carboxylates, alkaline earth metal carboxylates, ammonium carboxylates, alkali metal dihydrogen phosphates, alkaline earth metal dihydrogen phosphates, alkali metal hydrogen phosphates, alkaline earth metal hydrogen phosphates, alkali metal phosphates, alkaline earth metal phosphates and ammonium phosphate, alkali metal acetates, alkaline earth metal acetates, ammonium acetate, alkali metal formates, alkaline earth metal formates, ammonium formate, alkali metal oxalates, alkaline earth metal oxalates and ammonium oxalate.

摘要翻译： 一种在催化剂存在下具有至少两个腈基的低聚物氢化方法，在氢化开始之前，通过与选自碱金属碳酸盐，碱土金属碳酸盐，碳酸铵， 碱金属碳酸氢盐，碱土金属碳酸氢盐，碳酸氢铵，碱土金属碳酸盐，碱金属羧酸盐，碱土金属羧酸盐，羧酸铵，碱金属磷酸二氢盐，碱土金属磷酸二氢盐，碱金属磷酸氢盐，碱土金属氢氧化磷酸盐 ，碱金属磷酸盐，碱土金属磷酸盐和磷酸铵，碱金属乙酸盐，碱土金属乙酸盐，乙酸铵，碱金属甲酸盐，碱土金属甲酸盐，甲酸铵，碱金属草酸盐，碱土金属草酸盐和草酸铵。

公开(公告)号：US20080306299A1

公开(公告)日：2008-12-11

申请号：US12158200

申请日：2006-12-15

申请人： Martin Ernst ,  Andreas Kusche ,  Gunnar Heydrich ,  Horst Grafmans ,  Holger Evers ,  Johann-Peter Melder ,  Harald Meissner ,  Torsten Freund

发明人： Martin Ernst ,  Andreas Kusche ,  Gunnar Heydrich ,  Horst Grafmans ,  Holger Evers ,  Johann-Peter Melder ,  Harald Meissner ,  Torsten Freund

IPC分类号： C07C231/14

CPC分类号： C07C231/14 ,  Y02P20/582 ,  C07C237/06

摘要： The invention relates to a process for preparing aminoalkanamides by reacting cyanoalkanoic esters with a) ammonia or an amine and b) hydrogen in the presence of a catalyst, the reaction with component b) being started simultaneously or not later than a maximum of 100 minutes after commencement of the reaction of the cyanoalkanoic ester with component a).

摘要翻译： 本发明涉及一种通过氰基链烷酸酯与a）氨或胺反应制备氨基烷酰胺的方法，和b）在催化剂存在下使氢气反应，与组分b）的反应同时或不迟于最多100分钟开始 开始氰基链烷酸酯与组分a）的反应。

公开(公告)号：US20110172430A1

公开(公告)日：2011-07-14

申请号：US13119948

申请日：2009-09-09

申请人： Martin Ernst ,  Bernd Stein ,  Steffen Maas ,  Jörg Pastre ,  Thorsten Johann ,  Johann-Peter Melder

发明人： Martin Ernst ,  Bernd Stein ,  Steffen Maas ,  Jörg Pastre ,  Thorsten Johann ,  Johann-Peter Melder

IPC分类号： C07D211/00 ,  C07C209/00 ,  C07D207/06

CPC分类号： B01J23/72 ,  B01J21/04 ,  B01J35/023 ,  B01J37/0009 ,  B01J37/0201 ,  B01J37/18 ,  C07C209/16 ,  C07C209/26 ,  C07C2601/14 ,  Y02P20/582 ,  C07C211/08 ,  C07C211/10 ,  C07C211/12 ,  C07C211/14 ,  C07C211/35

摘要： Process for the continuous preparation of an amine by reaction of a primary or secondary alcohol, aldehyde and/or ketone with hydrogen and a nitrogen compound selected from the group consisting of ammonia, primary and secondary amines at a temperature in the range from 60 to 300° C. in the presence of a catalyst comprising copper oxide and aluminum oxide, wherein the reaction takes place in the gas phase and the catalytically active composition of the catalyst before reduction with hydrogen comprises PS from 20 to 75% by weight of aluminum oxide (Al2O3),from 20 to 75% by weight of oxygen-comprising compounds of copper, calculated as CuO, from 0 to 2% by weight of oxygen-comprising compounds of sodium, calculated as Na2O, and less than 5% by weight of oxygen-comprising compounds of nickel, calculated as NiO, and the shaped catalyst body has a pellet shape having a diameter in the range from 1 to 4 mm and a height in the range from 1 to 4 mm.

摘要翻译： 通过伯醇或仲醇，醛和/或酮与氢和选自氨，伯胺和仲胺的氮化合物在60至300℃的温度下反应来连续制备胺的方法 在包含氧化铜和氧化铝的催化剂存在下，其中反应在气相中进行，并且在用氢还原之前催化活性组合物包含20至75重量％的氧化铝（PS） Al 2 O 3），20至75重量％的含氧化合物的铜（以CuO计），0至2重量％的含氧化合物的钠（以Na 2 O计）和小于5重量％的氧 令人惊奇的以NiO计算的镍化合物，成型的催化剂体具有直径在1至4mm范围内且高度在1至4mm范围内的颗粒形状。

公开(公告)号：US07939027B2

公开(公告)日：2011-05-10

申请号：US12683015

申请日：2010-01-06

申请人： Martin Ernst ,  Steffen Oehlenschläger ,  Frank Kuhnke ,  Karl-Heinz Roβ ,  Roland Deeg ,  Johann-Peter Melder

发明人： Martin Ernst ,  Steffen Oehlenschläger ,  Frank Kuhnke ,  Karl-Heinz Roβ ,  Roland Deeg ,  Johann-Peter Melder

IPC分类号： B01J10/00 ,  C07C209/00 ,  B01J35/02 ,  B01J19/00 ,  B01J8/00

CPC分类号： C07C209/48 ,  B01J2219/00006 ,  C07C253/30 ,  C07C211/11 ,  C07C255/24

摘要： The present invention relates to a process for the industrial preparation of a diamine starting from a corresponding alkenyl nitrile comprising at least one C—C double bond, which comprises the steps (a) reaction of the alkenyl nitrile with a corresponding monoamine in a first reactor so that the monoamine adds exothermically onto the at least one double bond to form an aminoalkyl nitrile, with the monoamine and water being charged initially and the alkenyl nitrile being fed in; (b) evaporation of unreacted alkenyl nitrile and monoamine to increase the concentration of the aminoalkyl nitrile product in the bottoms of the first reactor; (c) transfer of the aminoalkyl nitrile bottom product from step (b) to a second reactor; (d) batchwise catalytic hydrogenation of the aminoalkyl nitrile transferred in step (c) to the diamine in the second reactor, with each batch being obtained by initially charging a catalyst suitable for the hydrogenation of nitriles to amines and also water, the desired diamine and a base, introducing hydrogen into the second reactor and feeding in the aminoalkyl nitrile transferred in step (c); and (e) isolation of the diamine and, if appropriate, repetition of the steps (a) to (e). The invention further relates to an apparatus for preparing these diamines and the use of the apparatuses. A preferred diamine is 3-dimethylaminopropylamine (DMAPA).

摘要翻译： 本发明涉及从包含至少一个C-C双键的相应链烯基腈开始工业制备二胺的方法，其包括步骤（a）在第一反应器中烯基腈与相应的单胺反应 使得单胺在至少一个双键上放热添加以形成氨基烷基腈，最初加入单胺和水，并加入链烯基腈; （b）蒸发未反应的烯基腈和单胺以增加第一反应器底部氨基烷基腈产物的浓度; （c）将氨基烷基腈底部产物从步骤（b）转移至第二反应器; （d）将步骤（c）中转移的氨基烷基腈分批催化氢化为第二反应器中的二胺，每个批次通过首先将适合于将腈氢化成的催化剂加入到胺中而得到，并且还需要水，所需的二胺和 碱，将氢气引入第二反应器并进料步骤（c）中转移的氨基烷基腈; 和（e）分离二胺，如果合适，重复步骤（a）至（e）。 本发明还涉及一种用于制备这些二胺的装置和该装置的用途。 优选的二胺是3-二甲基氨基丙胺（DMAPA）。

公开(公告)号：US20100036168A1

公开(公告)日：2010-02-11

申请号：US12520575

申请日：2007-12-19

申请人： Martin Ernst ,  Thomas Hill ,  Piotr Makarczyk ,  Johann-Peter Melder

发明人： Martin Ernst ,  Thomas Hill ,  Piotr Makarczyk ,  Johann-Peter Melder

IPC分类号： C07C209/48

CPC分类号： C07C209/48 ,  C07C209/52 ,  C07C2601/14 ,  C07C211/36

摘要： The present invention relates to a continuous process for preparing 3-aminomethyl-3,5,5-trimethylcyclohexylamine by reacting a feed stream comprising 3-cyano-3,5,5-trimethylcyclohexylimine with hydrogen and ammonia over hydrogenation catalysts, wherein the basicity of the reaction mixture is increased during the reaction by bringing the reaction mixture into contact with a basic compound which is not ammonia and/or a basic catalyst after part of the 3-cyano-3,5,5-trimethylcyclohexylimine has been reacted.

摘要翻译： 本发明涉及通过在氢化催化剂上使包含3-氰基-3,5,5-三甲基环己基亚胺的进料流与氢和氨反应制备3-氨基甲基-3,5,5-三甲基环己胺的连续方法，其中碱 反应混合物在反应过程中通过在部分3-氰基-3,5,5-三甲基环己基亚胺反应后使反应混合物与不是氨和/或碱性催化剂的碱性化合物接触而增加。

公开(公告)号：US20080293973A1

公开(公告)日：2008-11-27

申请号：US12092684

申请日：2006-10-31

申请人： Martin Ernst ,  Steffen Oehlenschlager ,  Frank Kuhnke ,  Karl-Heinz Ross ,  Roland Deeg ,  Johann-Peter Melder

发明人： Martin Ernst ,  Steffen Oehlenschlager ,  Frank Kuhnke ,  Karl-Heinz Ross ,  Roland Deeg ,  Johann-Peter Melder

IPC分类号： C07C209/48 ,  B01J19/00

CPC分类号： B01J8/20 ,  B01D3/14 ,  B01J2219/00006 ,  B01J2219/00029 ,  B01J2219/0004 ,  C07C209/48 ,  C07C211/11

摘要： The present invention relates to a process for the industrial preparation of a diamine starting from a corresponding alkenyl nitrile comprising at least one C-C double bond, which comprises the steps (a) reaction of the alkenyl nitrile with a corresponding monoamine in a first reactor so that the monoamine adds exothermically onto the at least one double bond to form an aminoalkyl nitrile, with the monoamine and water being charged initially and the alkenyl nitrile being fed in; (b) evaporation of unreacted alkenyl nitrile and monoamine to increase the concentration of the aminoalkyl nitrile product in the bottoms of the first reactor; (c) transfer of the aminoalkyl nitrile bottom product from step (b) to a second reactor; (d) batchwise catalytic hydrogenation of the aminoalkyl nitrile transferred in step (c) to the diamine in the second reactor, with each batch being obtained by initially charging a catalyst suitable for the hydrogenation of nitriles to amines and also water, the desired diamine and a base, introducing hydrogen into the second reactor and feeding in the aminoalkyl nitrile transferred in step (c); and (e) isolation of the diamine and, if appropriate, repetition of the steps (a) to (e). The invention further relates to an apparatus for preparing these diamines and the use of the apparatuses. A preferred diamine is 3-dimethylaminopropylamine (DMAPA).

摘要翻译： 本发明涉及从包含至少一个CC双键的相应烯基腈开始工业制备二胺的方法，其包括步骤（a）在第一反应器中使链烯基腈与相应的单胺反应，使得 单胺在至少一个双键上放热添加以形成氨基烷基腈，最初加入单胺和水，并加入链烯基腈; （b）蒸发未反应的烯基腈和单胺以增加第一反应器底部氨基烷基腈产物的浓度; （c）将氨基烷基腈底部产物从步骤（b）转移至第二反应器; （d）将步骤（c）中转移的氨基烷基腈分批催化氢化为第二反应器中的二胺，每个批次通过首先将适合于将腈氢化成的催化剂加入到胺中而得到，并且还需要水，所需的二胺和 碱，将氢气引入第二反应器并进料步骤（c）中转移的氨基烷基腈; 和（e）分离二胺，如果合适，重复步骤（a）至（e）。 本发明还涉及一种用于制备这些二胺的装置和该装置的用途。 优选的二胺是3-二甲基氨基丙胺（DMAPA）。

公开(公告)号：US08884063B2

公开(公告)日：2014-11-11

申请号：US12520575

申请日：2007-12-19

申请人： Martin Ernst ,  Thomas Hill ,  Piotr Makarczyk ,  Johann-Peter Melder

发明人： Martin Ernst ,  Thomas Hill ,  Piotr Makarczyk ,  Johann-Peter Melder

IPC分类号： C07C209/00 ,  C07C209/52 ,  C07C209/48

CPC分类号： C07C209/48 ,  C07C209/52 ,  C07C2601/14 ,  C07C211/36

摘要： The present invention relates to a continuous process for preparing 3-aminomethyl-3,5,5-trimethylcyclohexylamine by reacting a feed stream comprising 3-cyano-3,5,5-trimethylcyclohexylimine with hydrogen and ammonia over hydrogenation catalysts, wherein the basicity of the reaction mixture is increased during the reaction by bringing the reaction mixture into contact with a basic compound which is not ammonia and/or a basic catalyst after part of the 3-cyano-3,5,5-trimethylcyclohexylimine has been reacted.

摘要翻译： 本发明涉及通过在氢化催化剂上使包含3-氰基-3,5,5-三甲基环己基亚胺的进料流与氢和氨反应制备3-氨基甲基-3,5,5-三甲基环己胺的连续方法，其中碱 反应混合物在反应过程中通过在部分3-氰基-3,5,5-三甲基环己基亚胺反应后使反应混合物与不是氨和/或碱性催化剂的碱性化合物接触而增加。

公开(公告)号：US08759580B2

公开(公告)日：2014-06-24

申请号：US12158200

申请日：2006-12-15

申请人： Martin Ernst ,  Andreas Kusche ,  Gunnar Heydrich ,  Horst Grafmans ,  Holger Evers ,  Johann-Peter Melder ,  Harald Meiβner ,  Torsten Freund

发明人： Martin Ernst ,  Andreas Kusche ,  Gunnar Heydrich ,  Horst Grafmans ,  Holger Evers ,  Johann-Peter Melder ,  Harald Meiβner ,  Torsten Freund

IPC分类号： C07C231/04

CPC分类号： C07C231/14 ,  Y02P20/582 ,  C07C237/06

摘要： The invention relates to a process for preparing aminoalkanamides by reacting cyanoalkanoic esters with a) ammonia or an amine and b) hydrogen in the presence of a catalyst, the reaction with component b) being started simultaneously or not later than a maximum of 100 minutes after commencement of the reaction of the cyanoalkanoic ester with component a).

摘要翻译： 本发明涉及一种通过氰基链烷酸酯与a）氨或胺反应制备氨基烷酰胺的方法，和b）在催化剂存在下使氢气反应，与组分b）的反应同时或不迟于最多100分钟开始 开始氰基链烷酸酯与组分a）的反应。