公开(公告)号：US08070747B2

公开(公告)日：2011-12-06

申请号：US11472924

申请日：2006-06-21

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

IPC分类号： A61B18/14

CPC分类号： A61B17/0057 ,  A61B17/3439 ,  A61B18/1445 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/306 ,  A61B2017/3445 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

公开(公告)号：US08038669B2

公开(公告)日：2011-10-18

申请号：US11249566

申请日：2005-10-12

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

IPC分类号： A61B18/14

CPC分类号： A61B17/0057 ,  A61B17/3439 ,  A61B18/1445 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/306 ,  A61B2017/3445 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

公开(公告)号：US08016871B2

公开(公告)日：2011-09-13

申请号：US12482227

申请日：2009-06-10

申请人： Sunmi Chew ,  Bernard Andreas ,  Hanson S. Gifford, III ,  Ron French ,  Mark E. Deem ,  Allan Will

发明人： Sunmi Chew ,  Bernard Andreas ,  Hanson S. Gifford, III ,  Ron French ,  Mark E. Deem ,  Allan Will

IPC分类号： A61F2/06

CPC分类号： A61F2/958 ,  A61F2/0095 ,  A61F2/91 ,  A61F2/915 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2002/91533 ,  A61F2002/91541 ,  A61F2002/9155 ,  A61F2002/91558 ,  A61F2002/91591 ,  A61F2002/9583 ,  A61F2210/0033 ,  A61F2210/0042 ,  A61F2250/0071

摘要： Blood vessels and other body lumens are stented using multiple, discreet stent structures. Stent structures may be balloon expandable or self-expanding and are delivered by a delivery catheter which is repositioned to spaced-apart delivery sights. By coating the stents with particular biologically active substances, hyperplasia within and between the implanted stents can be inhibited. An exemplary delivery catheter comprises a catheter body having both a pusher rod for advancing the stents relative to a sheath and a reciprocatable delivery catheter for implanting the stents.

摘要翻译： 使用多个谨慎的支架结构支架血管和其他体腔。 支架结构可以是球囊扩张的或自膨胀的，并且通过输送导管输送，所述输送导管重新定位到间隔开的输送瞄准镜。 通过用特定生物活性物质涂覆支架，可以抑制植入支架内和植入支架之间的增生。 示例性递送导管包括具有用于相对于护套推进支架的推杆和用于植入支架的可往复运送的输送导管的导管主体。

公开(公告)号：US20110178589A1

公开(公告)日：2011-07-21

申请号：US13078749

申请日：2011-04-01

申请人： Bernard Andreas ,  Ron French ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Allan Will

发明人： Bernard Andreas ,  Ron French ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Allan Will

IPC分类号： A61F2/84

CPC分类号： A61F2/95 ,  A61B1/00151 ,  A61F2/966 ,  A61F2002/9517 ,  Y10S623/903

摘要： Blood vessels and other body lumens are expanded using an evertible braided prosthesis. The braided prosthesis is delivered to the blood vessel in a radially collapsed configuration. A leading edge of the braided prosthesis is then everted so that it expands as it is advanced through the blood vessel. Optionally, the prosthesis can be provided with a biologically active substance in order to inhibit hyperplasia or have other desired biological effects.

摘要翻译： 使用可逆的编织假体扩张血管和其他体腔。 编织的假体以径向收缩的构型输送到血管。 然后，编织假体的前缘被转动，使得它在其通过血管前进时膨胀。 任选地，假体可以具有生物活性物质，以便抑制增生或具有其它所需的生物效应。

公开(公告)号：US07909838B2

公开(公告)日：2011-03-22

申请号：US11654709

申请日：2007-01-18

申请人： Mark E. Deem ,  Douglas S. Sutton ,  Hanson S. Gifford, III ,  Bernard H. Andreas ,  Ronald G. French

发明人： Mark E. Deem ,  Douglas S. Sutton ,  Hanson S. Gifford, III ,  Bernard H. Andreas ,  Ronald G. French

IPC分类号： A61B17/08

CPC分类号： A61B17/1114 ,  A61B17/00234 ,  A61B17/064 ,  A61B17/0644 ,  A61B17/122 ,  A61B2017/00557 ,  A61B2017/306 ,  A61B2090/395 ,  A61F5/0083 ,  A61F5/0086

摘要： Various obesity treatment tools and methods are described herein, as well as treatments for other gastric-related diseases, e.g., GERD. Treatment includes reducing the size of the stomach pouch to limit the caloric intake as well as to provide an earlier feeling of satiety. This may be done by creating a smaller gastric pouch within the stomach directly from the interior of the stomach itself. The smaller pouches may be made through the use of individual anchoring devices, rotating probes, or volume reduction devices. A pyloroplasty procedure may also be performed to render the pyloric sphincter incompetent. A gastric bypass procedure may additionally be performed using atraumatic magnetic anastomoses devices so that sugars and fats are passed directly to the bowel while bypassing the stomach. Many of these procedures may be done in a variety of combinations. Treatment may create enforced behavioral modifications by discouraging the ingestion of high-caloric foods.

公开(公告)号：US07905913B2

公开(公告)日：2011-03-15

申请号：US11563847

申请日：2006-11-28

申请人： Sunmi Chew ,  Bernard Andreas ,  Hanson S. Gifford, III ,  Ron French ,  Mark E. Deem ,  Allan Will

发明人： Sunmi Chew ,  Bernard Andreas ,  Hanson S. Gifford, III ,  Ron French ,  Mark E. Deem ,  Allan Will

IPC分类号： A61F2/06

CPC分类号： A61F2/958 ,  A61F2/0095 ,  A61F2/91 ,  A61F2/915 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2002/91533 ,  A61F2002/91541 ,  A61F2002/9155 ,  A61F2002/91558 ,  A61F2002/91591 ,  A61F2002/9583 ,  A61F2210/0033 ,  A61F2210/0042 ,  A61F2250/0071

摘要： Blood vessels and other body lumens are stented using multiple, discreet stent structures. Stent structures may be balloon expandable or self-expanding and are delivered by a delivery catheter which is repositioned to spaced-apart delivery sights. By coating the stents with particular biologically active substances, hyperplasia within and between the implanted stents can be inhibited. An exemplary delivery catheter comprises a catheter body having both a pusher rod for advancing the stents relative to a sheath and a reciprocatable delivery catheter for implanting the stents.

公开(公告)号：US07662181B2

公开(公告)日：2010-02-16

申请号：US11395396

申请日：2006-03-30

申请人： Mark E. Deem ,  Hanson S. Gifford, III ,  Ronald French ,  Douglas S. Sutton

发明人： Mark E. Deem ,  Hanson S. Gifford, III ,  Ronald French ,  Douglas S. Sutton

IPC分类号： A61F2/20 ,  A61B1/12 ,  A62B9/02 ,  A62B9/06

CPC分类号： F16K15/147 ,  A61B17/12022 ,  A61B17/12104 ,  A61B17/12131 ,  A61B17/12172 ,  A61B17/221 ,  A61B2017/1205 ,  A61B2017/2215 ,  A61B2090/061 ,  A61F2/04 ,  A61F2/24 ,  A61F2/2403 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/91 ,  A61F2002/043 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  Y10S128/912

摘要： Systems, methods and devices for performing pulmonary procedures, and in particular treating lung disease. A flow control element includes a valve that prevents airflow in the inhalation direction but permits airflow in the exhalation direction. The flow control element is guided to and positioned at the site by a bronchoscope that is introduced into the patient's trachea and used to view the lungs during delivery of the flow control element. The valve may include one, two or more valve elements, and it may be collapsible for easier delivery. A source of vacuum or suction may be used to increase the amount of fluid withdrawn from the lung tissue. A device for measuring hollow structures, such as bronchioles, and a device for removing a previously-placed flow control element are disclosed as well.

摘要翻译： 用于执行肺部手术，特别是治疗肺部疾病的系统，方法和装置。 流量控制元件包括防止气流沿吸入方向但允许呼气方向气流的阀。 流量控制元件被引导到病人气管中并用于在流量控制元件的输送期间观察肺部的支气管镜引导到位置并定位在该位置处。 阀可以包括一个，两个或更多个阀元件，并且其可以是可折叠的以用于更容易的输送。 可以使用真空源或抽吸源来增加从肺组织排出的流体的量。 还公开了一种用于测量诸如细支气管的中空结构的装置和用于去除预先安置的流量控制元件的装置。

公开(公告)号：US20100010416A1

公开(公告)日：2010-01-14

申请号：US12561680

申请日：2009-09-17

申请人： Eugene De Juan, JR. ,  Stephen Boyd ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Dan Rosenman

发明人： Eugene De Juan, JR. ,  Stephen Boyd ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Dan Rosenman

IPC分类号： A61F9/00

CPC分类号： A61F9/00781 ,  A61B34/70 ,  A61B90/00 ,  A61F2/14 ,  A61F2/142 ,  A61F9/0008 ,  A61F9/0017 ,  A61F9/007 ,  A61F9/00736 ,  A61F9/0133 ,  A61F11/00 ,  A61F2250/0001 ,  A61F2250/0096 ,  A61F2250/0097 ,  A61K9/0051 ,  A61M27/002 ,  A61M2202/04 ,  A61M2210/0612

摘要： Methods and devices are adapted for implanting into the eye. An incision is formed in the cornea of the eye and a shunt is inserted through the incision into the anterior chamber of the eye. The shunt includes a fluid passageway. The shunt is passed along a pathway from the anterior chamber through the scleral spur of the eye into the suprachoroidal space and positioned in a first position such that a first portion of the fluid passageway communicates with the anterior chamber and a second portion of the fluid passageway communicates with the suprachoroidal space to provide a fluid passageway between the suprachoroidal space and the anterior chamber.

摘要翻译： 方法和装置适于植入眼睛。 在眼睛的角膜中形成切口，并且通过切口将分路插入眼睛的前房。 分流器包括流体通道。 所述分流器沿着从所述前房通过所述眼睛的巩膜刺入所述脉管外空间的路径通过并且定位在第一位置，使得所述流体通道的第一部分与所述前房连通，并且所述流体通道的第二部分 与脉管外空间连通，以在脉络膜上空间和前房之间提供流体通道。

公开(公告)号：US20100004729A1

公开(公告)日：2010-01-07

申请号：US12482227

申请日：2009-06-10

申请人： Sunmi Chew ,  Bernard Andreas ,  Hanson S. Gifford, III ,  Ron French ,  Mark E. Deem ,  Allan Will

发明人： Sunmi Chew ,  Bernard Andreas ,  Hanson S. Gifford, III ,  Ron French ,  Mark E. Deem ,  Allan Will

IPC分类号： A61F2/06

CPC分类号： A61F2/958 ,  A61F2/0095 ,  A61F2/91 ,  A61F2/915 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2002/91533 ,  A61F2002/91541 ,  A61F2002/9155 ,  A61F2002/91558 ,  A61F2002/91591 ,  A61F2002/9583 ,  A61F2210/0033 ,  A61F2210/0042 ,  A61F2250/0071

摘要： Blood vessels and other body lumens are stented using multiple, discreet stent structures. Stent structures may be balloon expandable or self-expanding and are delivered by a delivery catheter which is repositioned to spaced-apart delivery sights. By coating the stents with particular biologically active substances, hyperplasia within and between the implanted stents can be inhibited. An exemplary delivery catheter comprises a catheter body having both a pusher rod for advancing the stents relative to a sheath and a reciprocatable delivery catheter for implanting the stents.

摘要翻译： 使用多个谨慎的支架结构支架血管和其他体腔。 支架结构可以是球囊扩张的或自膨胀的，并且通过输送导管输送，所述输送导管重新定位到间隔开的输送瞄准镜。 通过用特定生物活性物质涂覆支架，可以抑制植入支架内和植入支架之间的增生。 示例性递送导管包括具有用于相对于护套推进支架的推杆和用于植入支架的可往复运送的输送导管的导管主体。

公开(公告)号：US20090264979A1

公开(公告)日：2009-10-22

申请号：US12492828

申请日：2009-06-26

申请人： Stephen Kao ,  Bernard Andreas ,  Hanson S. Gifford, III ,  Mark E. Deem ,  David W. Snow ,  Jeffry J. Grainger

发明人： Stephen Kao ,  Bernard Andreas ,  Hanson S. Gifford, III ,  Mark E. Deem ,  David W. Snow ,  Jeffry J. Grainger

IPC分类号： A61F2/06

CPC分类号： A61F2/95 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/9155 ,  A61F2002/9583

摘要： Blood vessels and other body lumens are stented using stent structures comprising a plurality of radially expansible rings where at least some of the rings comprise axially extending elements which interleave with axially extending elements on adjacent unconnected rings. The ring structures may be open cell structures or closed cell structures, and the axially extending elements will typically be formed as part of the open cell or closed cell structure.

摘要翻译： 使用包括多个可径向扩张的环的支架结构对血管和其他体腔进行支架，其中至少一些环包括轴向延伸的元件，其与相邻未连接的环上的轴向延伸的元件交错。 环结构可以是开孔结构或闭孔结构，并且轴向延伸的元件通常将形成为开孔或闭孔结构的一部分。