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公开(公告)号：US09878995B2
公开(公告)日：2018-01-30
申请号：US15429086
申请日：2017-02-09
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Gayatri Balan , Chien-Hung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D401/14
CPC classification number: C07D498/04 , C07B59/002 , C07B2200/05 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D495/04
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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公开(公告)号：US20170362201A1
公开(公告)日：2017-12-21
申请号：US15697755
申请日：2017-09-07
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Gayatri Balan , Chien-Hung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D401/12 , C07D453/02 , C07D417/14 , C07D413/14 , C07D413/12 , C07D409/14 , C07D405/14 , C07F7/08 , C07D401/14
CPC classification number: C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/14 , C07D453/02 , C07F7/0814
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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公开(公告)号：US09815818B2
公开(公告)日：2017-11-14
申请号：US15199779
申请日：2016-06-30
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Gayatri Balan , Chien-Hung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D401/12 , C07D401/14 , C07D405/14 , C07D413/12 , C07D453/02 , C07D409/14 , C07D413/14 , C07D417/14 , C07F7/08
CPC classification number: C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/14 , C07D453/02 , C07F7/0814
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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公开(公告)号：US20170137405A1
公开(公告)日：2017-05-18
申请号：US15357290
申请日：2017-02-03
Applicant: Gilead Sciences, Inc.
Inventor： Steven S. Bondy , Carina E. Cannizzaro , Chien-Hung Chou , Randall L. Halcomb , Yunfeng Eric Hu , John O. Link , Qi Liu , Scott D. Schroeder , Winston C. Tse , Jennifer R. Zhang
IPC: C07D401/12
CPC classification number: C07D401/12 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/4709 , A61K31/4985 , A61K31/50 , A61K31/506 , A61K31/5377 , A61K45/06 , C07D213/40 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/12 , C07D409/14 , C07D413/14 , C07D471/04 , C07D471/06 , C07D487/04 , C07D491/04 , C07D491/052 , C07D495/04
Abstract: The invention provides compounds of formula (I): or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus.
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Patent Agency Ranking
公开(公告)号：US20170008905A1
公开(公告)日：2017-01-12
申请号：US15199534
申请日：2016-06-30
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Gayatri Balan , Chien-Hung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D498/04 , C07B59/00 , C07D471/04 , C07D409/14 , C07D417/14 , C07D495/04 , C07D401/14 , C07D405/14
CPC classification number: C07D498/04 , C07B59/002 , C07B2200/05 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D495/04
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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公开(公告)号：US20160067224A1
公开(公告)日：2016-03-10
申请号：US14943931
申请日：2015-11-17
Applicant: Gilead Sciences, Inc.
Inventor： Steven S. Bondy , Carina E. Cannizzaro , Chien-Hung Chou , John O. Link , Qi Liu , Scott D. Schroeder , Winston C. Tse , Jennifer R. Zhang
IPC: A61K31/4178 , A61K31/4192 , A61K31/437 , A61K31/427 , A61K31/4245 , A61K31/422 , A61K45/06 , A61K31/4196
CPC classification number: A61K31/4178 , A61K31/4192 , A61K31/4196 , A61K31/422 , A61K31/4245 , A61K31/427 , A61K31/437 , A61K45/06 , C07D403/12 , C07D413/12 , C07D417/12 , C07D471/04
Abstract: Compounds of formula I: or salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus.
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公开(公告)号：US09012441B2
公开(公告)日：2015-04-21
申请号：US14151762
申请日：2014-01-09
Applicant: Gilead Sciences, Inc.
Inventor： Steven S. Bondy , Carina E. Cannizzaro , Chien-Hung Chou , Yunfeng Eric Hu , John O. Link , Qi Liu , Scott D. Schroeder , Winston C. Tse , Jennifer R. Zhang
IPC: C07D487/04 , C07D513/04 , A61K31/00 , C07D471/14
CPC classification number: C07D513/04 , C07D471/14 , C07D487/04
Abstract: Compounds of formula I: or salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating a Retroviridae viral infection including an infection caused by the HIV virus.
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公开(公告)号：US08809267B2
公开(公告)日：2014-08-19
申请号：US13932945
申请日：2013-07-01
Applicant: Gilead Sciences, Inc.
Inventor： Jeromy J. Cottell , John O. Link , Scott D. Schroeder , James Taylor , Winston C. Tse , Randall W. Vivian , Zheng-Yu Yang
IPC: A61K38/00
CPC classification number: C07K5/0808 , A61K38/00 , C07D207/16 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/14 , C07D413/14 , C07D417/14 , C07D487/04 , C07D495/04 , C07K5/0804 , C07K5/0812 , C07K5/0821
Abstract: The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
Abstract translation: 本发明涉及抗病毒化合物，含有这些化合物的组合物和包括施用这些化合物的治疗方法以及可用于制备这些化合物的方法和中间体。
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公开(公告)号：US20140051656A1
公开(公告)日：2014-02-20
申请号：US13956195
申请日：2013-07-31
Applicant: Gilead Sciences, Inc.
Inventor： Hongyan Guo , Darryl Kato , Thorsten A. Kirschberg , Hongtao Liu , John O. Link , Michael L. Mitchell , Jay P. Parrish , Jianyu Sun , James Taylor , Elizabeth M. Bacon , Eda Canales , Aesop Cho , Choung U. Kim , Jeromy J. Cottell , Manoj C. Desai , Randall L. Halcomb , Michael Graupe , Evan S. Krygowski , Scott E. Lazerwith , Qi Liu , Richard L. Mackman , Hyung-Jung Pyun , Joseph H. Saugier , James D. Trenkle , Winston C. Tse , Randall W. Vivian , Scott D. Schroeder , William J. Watkins , Lianhong Xu
IPC: C07D403/14 , A61K45/06 , A61K31/4184
CPC classification number: C07D403/14 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/427 , A61K31/435 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/519 , A61K31/5377 , A61K31/5415 , A61K31/55 , A61K45/06 , A61P31/12 , C07D207/16 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D491/113 , C07D495/04 , C07F5/025
Abstract: The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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