摘要:
Stereospecific carbonyl reductases SCR1, SCR2, and SCR3 are described herein as are nucleotide sequences that encode these reductases. These stereospecific carbonyl reductases have anti-Prelog selectivity and have specificities that are useful for fine biochemical synthesis.
摘要:
A power switch circuit providing voltage to an output port is provided. The switch circuit includes a single power supply, a switch unit, a controlling unit, and a logic unit. The switch unit is connected between the single power supply and an output port and capable of being turned on and off alternatively for continuing or discontinuing power from the single power supply to the output port; the single power supply provides power to the output port. The controlling unit is configured for generating a voltage controlling signal and transmitting the voltage controlling signal to the logic unit. The logic unit receives and inverts the voltage controlling signal, and outputs the inverted voltage controlling signal to turn on or turn off the switch unit.
摘要:
An apparatus, system and method to optimize load distribution across logical and physical resources in a storage system. An apparatus in accordance with the invention may include an availability module and an allocation module. The availability module may dynamically assign values to resources in a hierarchical tree structure. Each value may correspond to an availability parameter such as allocated volumes, current resource utilization, and historic resource utilization. The allocation module may serially process the values and allocate a load to a least busy resource in the hierarchical tree structure based on the assigned values.
摘要:
A method to store point-in-time data, comprising establishing a block size, providing source data storage comprising (S) blocks, and target data storage comprising (T) blocks. The method configures (B) source storage segments and (B) target storage segments, and receives updated point-in-time data for original point-in-time data written to an (i)th source storage segment. The method then determines if a (j)th target storage segment comprises available storage capacity to store the original point-in-time data. If a (j)th target storage segment comprises available storage capacity to store the original point-in-time data, the method writes the original point-in-time data to that (j)th target storage segment.
摘要:
Methods and a kit are provided for selectively and exponentially amplifying nucleic acids and include the use of a helicase preparation and a DNA polymerase such that the amplification can be performed isothermally.
摘要:
A storage system includes a backend storage unit for storing electronic information; a controller unit for controlling reading and writing to the backend storage unit; and at least one of a cache and a non-volatile storage for storing the electronic information during at least one of the reading and the writing; the controller unit executing machine readable and machine executable instructions including instructions for: testing if a frequency of non-volatile storage full condition has occurred one of above and below an upper threshold frequency value and a lower threshold frequency value; if the frequency of the condition has exceeded a threshold frequency value, then calculating a new size; calculating an expected average response time for the new size; comparing actual response time to the expected response time; and one of adjusting and not adjusting a size of the non-volatile storage to minimize the response time.
摘要:
A method of detecting abasic (AP) sites in DNA from a subject includes isolating a sample of DNA from a subject under examination, contacting the DNA with a fluorescent aldehyde reactive probe (FARP), and detecting FARP labeled AP sites in the DNA sample.
摘要:
A mechanism for selectively disabling and enabling read caching based on past performance of the cache and current read/write requests. The system improves overall performance by using an autonomic algorithm to disable read caching for regions of backend disk storage (i.e., the backstore) that have had historically low cache hit ratios. The result is that more cache becomes available for workloads with larger hit ratios, and less time and machine cycles are spent searching the cache for data that is unlikely to be there.
摘要:
Recently, the development of inducible expression systems has involved exploitation of the p-cym operon from Pseudomonas putido. Disclosed herein are novel expression systems and components thereof, which involve the development of CymR variants with reverse DNA binding activity, such that they exhibit increased affinity for DNA in a presence rather than an absence of an effector molecule such as cumene or an equivalent thereof. Also disclosed are the CymR variants, fusion proteins incorporating such variants, and their use in the control and expression of polynucleotides.
摘要:
Methods and a kit are provided for selectively and exponentially amplifying nucleic acids and include the use of a helicase preparation and a DNA polymerase such that the amplification can be performed isothermally.