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    MIMO receiver using maximum likelihood detector in combination with QR decomposition
    72.
    发明授权
    MIMO receiver using maximum likelihood detector in combination with QR decomposition 有权
    使用最大似然检测器与QR分解相结合的MIMO接收机

    公开(公告)号：US07489746B1

    公开(公告)日：2009-02-10

    申请号：US11112068

    申请日：2005-04-22

    申请人： Geert A. Awater ,  Brian Wong

    发明人： Geert A. Awater ,  Brian Wong

    IPC分类号： H03D1/00 ,  H04L27/06

    CPC分类号： H04L25/0246 ,  H04B7/0413 ,  H04B7/0851 ,  H04B7/0854 ,  H04L1/06 ,  H04L2025/03426

    摘要： A MIMO receiver is provided with a preprocessor for performing QR decomposition of a channel matrix H wherein the factored reduced matrix R is used in place of H and Q*y is used in place of the received vector y in a maximum likelihood detector (“MLD”). The maximum likelihood detector might be a hard-decision MLD or a soft-decision MLD. A savings of computational complexity can be used to provide comparable results more quickly, using less circuitry, and/or requiring less consumed energy, or performance can be improved for a fixed amount of time, circuitry and/or energy. Where the MLD uses approximations, such as finite resolution calculations (fixed point or the like) or L1 Norm approximations, the reduced number of operations resulting from using the reduced matrix results in improved approximations as a result of the finite resolution operations. Other methods of reducing the channel matrix might be used for suitable and/or cumulative advantages.

    摘要翻译： MIMO接收机设置有用于执行信道矩阵H的QR分解的预处理器，其中使用因子减小矩阵R代替H，并且使用Q * y代替最大似然检测器（“MLD”）中的接收向量y “）。 最大似然检测器可能是硬判决MLD或软判决MLD。 可以使用较少的电路和/或需要更少的消耗的能量来节省更多的计算复杂度来提供可比较的结果，或者可以在固定的时间，电路和/或能量的情况下提高性能。 在MLD使用近似值（例如有限分辨率计算（固定点等）或L1 Norm近似）的情况下，由于使用简化矩阵导致的减少的操作数导致由于有限分辨率操作而导致的改进的近似。 降低通道矩阵的其他方法可用于合适和/或累积的优点。

    Protein belonging to the TNF superfamily involved in signal transduction, nucleic acids encoding same, and methods of use thereof
    73.
    发明授权
    Protein belonging to the TNF superfamily involved in signal transduction, nucleic acids encoding same, and methods of use thereof 有权
    涉及信号转导的TNF超家族的蛋白质，其编码的核酸及其使用方法

    公开(公告)号：US07393927B2

    公开(公告)日：2008-07-01

    申请号：US11032797

    申请日：2005-01-11

    申请人： Yongwon Choi ,  Brian Wong ,  Regis Josien ,  Ralph Steinman

    发明人： Yongwon Choi ,  Brian Wong ,  Regis Josien ,  Ralph Steinman

    IPC分类号： C07K14/525 ,  A61K38/19 ,  C12P21/02 ,  C07H21/04 ,  C12N1/20 ,  C12N5/02

    CPC分类号： C07K16/2875 ,  A61K38/00 ,  A61K39/00 ,  A61K48/00 ,  C07K14/525 ,  C07K14/70575 ,  C07K2317/76 ,  C07K2319/30 ,  C12N15/1096

    摘要： A method of modulating immune response in an animal is disclosed. Such a method interacting the immature dendritic cells from the animal with an antigen ex vivo so that the immature dendritic cells present the antigen on their surfaces, inducing maturation of the immature dendritic cells ex vivo, and contacting the mature dendritic cells ex vivo with a modulator comprising TRANCE, conservative variants thereof, fragments thereof, analogs or derivatives thereof, or a fusion protein comprising the amino acid sequence of TRANCE, conservative variants thereof, or fragments thereof. After contacting the modulator ex vivo, the mature dendritic cells are introduced into the animal. As a result, immune response in the animal towards the antigen is modulated relative to the immune response against the antigen in an animal in which dendritic cells did not interact with the antigen ex vivo, and did not contact a modulator ex vivo. Preferably, the method of the present invention results in increasing immune response towards the antigen in the animal.

    摘要翻译： 公开了调节动物免疫应答的方法。 这种方法将来自动物的未成熟树突状细胞与抗原离体相互作用，使得未成熟树突细胞在其表面上存在抗原，诱导未成熟树突状细胞离体成熟，并使成熟树突状细胞离体与调节剂接触 包括TRANCE，其保守变体，其片段，其类似物或衍生物，或包含TRANCE的氨基酸序列，其保守变体或其片段的融合蛋白。 离体调节剂离体接触后，将成熟树突状细胞导入动物体内。 因此，动物中针对抗原的免疫反应相对于动物中针对抗原的免疫应答进行调节，其中树突细胞离体不与抗原相互作用，并且不离体接触调节剂。 优选地，本发明的方法导致对动物中抗原的免疫应答增加。

    System and method for generating a probability distribution of computer performance ratios
    75.
    发明申请
    System and method for generating a probability distribution of computer performance ratios 有权
    用于生成计算机性能比的概率分布的系统和方法

    公开(公告)号：US20070124353A1

    公开(公告)日：2007-05-31

    申请号：US11291184

    申请日：2005-11-30

    申请人： Adrian Cockcroft ,  Brian Wong ,  Allan Packer

    发明人： Adrian Cockcroft ,  Brian Wong ,  Allan Packer

    IPC分类号： G06F15/00

    CPC分类号： G06F11/3428

    摘要： A system and method for generating a probability distribution indicating the probability of a range of performance ratios between computer systems. Benchmark and/or other testing results are obtained for both computer systems. For each test, a ratio of one system's performance to the other is calculated. The ratios and/or testing results may be weighted. From the performance ratios, a histogram is produced to indicate the probabilities of achieving the various ratios. Based on the distribution of probabilities, a particular performance ratio can be predicted with a corresponding level of confidence, and used for capacity planning or configuring a computing environment.

    摘要翻译： 一种用于生成表示计算机系统之间的性能比范围的概率的概率分布的系统和方法。 为两个计算机系统获得基准和/或其他测试结果。 对于每个测试，计算一个系统的性能与另一个系统的性能的比率。 比率和/或测试结果可以加权。 从性能比，产生直方图以指示实现各种比率的概率。 基于概率分布，可以用相应的置信度预测特定的性能比，并用于容量规划或配置计算环境。

    Two Cards Combo 21
    76.
    发明申请
    Two Cards Combo 21 审中-公开
    两张卡组合21

    公开(公告)号：US20070069468A1

    公开(公告)日：2007-03-29

    申请号：US11237460

    申请日：2005-09-27

    申请人： Hui Chen ,  Brian Wong

    发明人： Hui Chen ,  Brian Wong

    IPC分类号： A63F1/00

    CPC分类号： A63F1/00 ,  A63F2001/003

    摘要： Two Cards Combo 21 is a card game in convention with the playing method of Blackjack (twenty-one) that multiple players engage in taking turns to play their own hand against to dealer's hand. A method of playing Two Cards Combo 21 card game comprises a dealer and at least one player. It uses a shoe with six decks or eight decks of standard playing card without jokers, queens and kings (44 cards of each deck). In conjunction with standard rules of Blackjack, there are one mandatory bet which is Ante (Two cards Combo 21) and five side bets, such as, Dealer Bust, Any Pair of 2, 3, 4, 5, 6, 7, 8, 9, 10, jack, and ace, Blackjack or Combo 21, Any Even number, and Any Odd number.

    摘要翻译： 两张卡组合21是与二十一点（二十一）的玩法一样的纸牌游戏，多名玩家轮流对自己的手进行自己的手。 玩二卡组合21纸牌游戏的方法包括经销商和至少一个玩家。 它使用的鞋子有六个甲板或八个标准扑克牌，没有小丑，皇后和国王（每张甲板上的44张卡）。 结合二十一点的标准规则，有一个强制性赌注是安特（两张牌组合21）和五个侧注，如经销商胸围，任何一对2,3,4,5,6,7,8， 9，10，jack和ace，21点或者组合21，任意偶数，任意奇数。

    Method and apparatus for skip-free retiming transmission of digital information
    77.
    发明授权
    Method and apparatus for skip-free retiming transmission of digital information 有权
    数字信息的无跳跃重新定时传输的方法和装置

    公开(公告)号：US07194059B2

    公开(公告)日：2007-03-20

    申请号：US10223842

    申请日：2002-08-19

    申请人： Brian Wong ,  Benjamim Tang ,  Scott Southwell ,  Allen Sakai

    发明人： Brian Wong ,  Benjamim Tang ,  Scott Southwell ,  Allen Sakai

    IPC分类号： H04L23/00

    CPC分类号： H04L25/242

    摘要： A skip-free retiming system and method for transmission of digital information in a plesiochronous data communication system is described. The system is capable of supporting an unlimited number of retimers in serial data path between a first and a last node. The retimers are configured to retime, amplify and retransmit a received data stream without altering the received data rate. Thus, the data rate from the first node is received at the same frequency at the last node, regardless of the number of retimers. In general, the retimer performs rate compensation on a retimer local clock, rather than on the data stream, so the attributes of the clean retimer clock can be applied to the data stream without changing the data rate.

    摘要翻译： 描述了一种用于在同步数据通信系统中传输数字信息的无跳越重定时系统和方法。 该系统能够在第一和最后一个节点之间的串行数据路径中支持无限数量的重新定时器。 重新配置配置用于重新计算，放大和重传接收的数据流，而不改变接收到的数据速率。 因此，来自第一节点的数据速率在最后一个节点处以相同的频率被接收，而不管重定时器的数量如何。 通常，重定时器在重定时器本地时钟而不是在数据流上执行速率补偿，因此干净的重新定时器时钟的属性可以应用于数据流而不改变数据速率。

    Trance activated signal transduction pathways in osteoclasts
    80.
    发明授权
    Trance activated signal transduction pathways in osteoclasts 有权
    恍惚激活信号转导通路在破骨细胞

    公开(公告)号：US06492124B1

    公开(公告)日：2002-12-10

    申请号：US09330867

    申请日：1999-06-11

    申请人： Brian Wong ,  Daniel Besser ,  Yongwon Choi

    发明人： Brian Wong ,  Daniel Besser ,  Yongwon Choi

    IPC分类号： G01N33567

    CPC分类号： C07K14/70575 ,  G01N33/6863 ,  G01N33/6887 ,  G01N2500/00

    摘要： The present invention relates to methods and compositions for modulating activity of a TRANCE receptor, including the modulation of TRANCE signaling activity. In particular, the invention provides screening methods by which novel modulators of TRANCE signaling may be identified, including TRANCE inhibitors, agonists and antagonists. The invention also relates to the identification of one or more specific pathways for osteoclast surivival, and the manipulation of this pathway (e.g., using a TRANCE modulator of the invention). Such manipulation may provide strategies for treating osteoclast-related diseases such as osteoporosis and osteopetrosis.

    摘要翻译： 本发明涉及用于调节TRANCE受体活性的方法和组合物，包括TRANCE信号传导活性的调节。 特别地，本发明提供了可以鉴定TRANCE信号传导的新型调节剂的筛选方法，包括TRANCE抑制剂，激动剂和拮抗剂。 本发明还涉及鉴定破骨细胞周转的一个或多个特异性途径，以及对该途径的操作（例如，使用本发明的TRANCE调节剂）。 这种操作可以提供治疗破骨细胞相关疾病如骨质疏松症和骨硬化症的策略。