COLORED, DYNAMIC, AND AMPLIFIED SAFETY FILM
    72.
    发明申请
    COLORED, DYNAMIC, AND AMPLIFIED SAFETY FILM 有权
    彩色,动态和放大安全膜

    公开(公告)号:US20150198749A1

    公开(公告)日:2015-07-16

    申请号:US14419151

    申请日:2012-08-03

    IPC分类号: G02B3/00 G02B5/28

    摘要: A colored, dynamic, and amplified security film includes a micro lens array layer, a base material layer, and a micro graphic layer. The layers meet the condition of Moore amplified imaging; the micro graphic layer is formed by a background area and a graphic area; the graphic area is distributed in the background area; the micro graphic layer includes a semi-transparent and semi-reflective metal layer, a medium layer, and a metal film layer successively from top to bottom; the metal film layer is of a planar structure; the thickness of the medium layer in the graphic area is greater than the thickness of the medium layer in the background area; and the thicknesses of semi-transparent and semi-reflective metal layers are consistent.

    摘要翻译: 彩色,动态和放大的安全膜包括微透镜阵列层,基材层和微图形层。 这些层符合摩尔放大成像条件; 微图形层由背景区域和图形区域形成; 图形区域分布在背景区域; 微图形层从上到下依次包括半透明和半反射金属层,介质层和金属膜层; 金属膜层是平面结构的; 图形区域中的介质层的厚度大于背景区域中介质层的厚度; 并且半透明和半反射金属层的厚度是一致的。

    Detection of T-wave alternans phase reversal for arrhythmia prediction and sudden cardiac death risk stratification
    75.
    发明授权
    Detection of T-wave alternans phase reversal for arrhythmia prediction and sudden cardiac death risk stratification 有权
    检测心律失常预测和心源性猝死危险分层的T波交替相逆转

    公开(公告)号:US08620414B2

    公开(公告)日:2013-12-31

    申请号:US12749753

    申请日:2010-03-30

    IPC分类号: A61B5/0452

    摘要: An implantable medical device and associated method for classifying a patient's risk for arrhythmias by sensing a cardiac electrogram (EGM) signal and selecting a first pair of T-wave signals and a second pair of T-wave signals. A first difference between the two T-wave signals of the first pair is compared to a second difference between the two T-wave signals of the second pair. A T-wave alternans phase reversal is detected in response to comparing the first difference and the second difference, and the patient's arrhythmia risk is classified in response to detecting the phase reversal.

    摘要翻译: 一种用于通过感测心电图(EGM)信号和选择第一对T波信号和第二对T波信号来分类患者心律失常风险的可植入医疗装置和相关方法。 将第一对的两个T波信号之间的第一个差异与第二对的两个T波信号之间的第二个差值进行比较。 响应于比较第一个差异和第二个差异,检测到T波交替相位逆转,并且响应于检测相位反转来分类患者的心律失常风险。

    INHIBITION OF RETINAL CELL DEGENERATION OR NEOVASCULARIZATION BY CERIUM OXIDE NANOPARTICLES
    79.
    发明申请
    INHIBITION OF RETINAL CELL DEGENERATION OR NEOVASCULARIZATION BY CERIUM OXIDE NANOPARTICLES 审中-公开
    通过氧化氮纳米颗粒抑制细胞衰老或新生血管细胞

    公开(公告)号:US20110111007A1

    公开(公告)日:2011-05-12

    申请号:US12772523

    申请日:2010-05-03

    CPC分类号: A61K33/00

    摘要: The presently claimed and disclosed inventive concept(s) provides methods for reducing, reversing or inhibiting retinal cell degeneration, or neovascularization in tissues of a mammalian subject having a pathological condition involving neovascularization, by administration in vivo of nanoceria particles (cerium oxide nanoparticles) to the subject. The method of the presently claimed and disclosed inventive concept(s) is useful, for example, for reducing, treating, reversing or inhibiting degeneration of retinal cells such as photoreceptor cells or neovascularization in ocular tissue such as the retina, macula or cornea; or other tissues such as, but not limited to, skin, synovial tissue, intestinal tissue, or bone. In addition, the method of the presently claimed and disclosed inventive concept(s) is useful for reducing or inhibiting neovascularization in a neoplasm (tumors), which can be benign or malignant and, where malignant, can be a metastatic neoplasm. As such, the presently claimed and disclosed inventive concept(s) is directed to using compositions containing nanoceria particles to reduce, treat, reverse or inhibit angiogenesis in a mammalian subject.

    摘要翻译: 目前要求权利要求和公开的发明构思通过在体内施用纳米颗粒(二氧化铈纳米颗粒)至哺乳动物受试者具有新生血管形成病理状态的组织中的视网膜细胞变性或新生血管形成, 主题。 目前权利要求和公开的发明构思的方法可用于例如减少,治疗,逆转或抑制视网膜细胞如感光细胞的变性或眼组织如视网膜,黄斑或角膜中的新生血管形成; 或其它组织,例如但不限于皮肤,滑膜组织,肠组织或骨。 此外,本发明权利要求和公开的发明构思的方法可用于减少或抑制肿瘤(肿瘤)中的新生血管形成,所述肿瘤可能是良性或恶性的,并且恶性肿瘤可以是转移性肿瘤。 因此,目前要求保护和公开的发明构思涉及使用含有纳米颗粒的组合物来减少,治疗,逆转或抑制哺乳动物受试者的血管发生。

    IMPLANTABLE MEDICAL DEVICE FOR CARDIAC ELECTRICAL STIMULATION
    80.
    发明申请
    IMPLANTABLE MEDICAL DEVICE FOR CARDIAC ELECTRICAL STIMULATION 审中-公开
    用于心脏电刺激的可植入医疗装置

    公开(公告)号:US20100298901A1

    公开(公告)日:2010-11-25

    申请号:US12771217

    申请日:2010-04-30

    IPC分类号: A61N1/362 A61N1/36

    摘要: A method and apparatus for reducing a patient's heart rate or blood pressure. The apparatus provides stimulation to the patient's atrial and/or nodal tissue within the associated refractory period of the ventricle but outside of an associated refractory period of the stimulated atrial an/or nodal tissue, responsive to detecting an occurrence of a ventricular depolarization following a preceding atrial depolarization.The apparatus may define a time window following the ventricular depolarization, following the atrial depolarization or determined based upon the timing of both the atrial and ventricular depolarizations. The stimulus may be delivered during or on expiration of the defined time window. The duration of the time window may be pre-set or determined based upon measurements of the patient's refractory periods.

    摘要翻译: 一种减轻患者心率或血压的方法和装置。 该装置响应于检测在前面的心室去极化的发生之后,在心室的相关不应期内但在受刺激的心房和/或淋巴结组织的相关不应期之外对患者的心房和/或淋巴结组织提供刺激。 心房去极化。 该装置可以在心房去极化之后定义心室去极化之后的时间窗口,或者基于心房和心室去极化的时间确定。 刺激可以在定义的时间窗口期间或期满时传送。 时间窗口的持续时间可以基于患者的不应期的测量来预先确定或确定。