SCAFFOLD-FREE SELF-ORGANIZED 3D SYNTHETIC TISSUE
    71.
    发明申请
    SCAFFOLD-FREE SELF-ORGANIZED 3D SYNTHETIC TISSUE 有权
    无SCAFF自由组织的3D合成组织

    公开(公告)号:US20080004713A1

    公开(公告)日:2008-01-03

    申请号:US11676172

    申请日:2007-02-16

    IPC分类号: A61F2/02

    摘要: The present invention can be used for actual implantation surgery without a scaffold. The present invention provides a synthetic tissue or complex which can be produced by culture and has a high level of differentiation ability. The present invention also provides a therapy and medicament for repairing and/or regenerating tissue using replacement and covering. By culturing cells under specific culture conditions such that medium contains an extracellular matrix synthesis promoting agent, the cells are organized and are easily detached from a culture dish. The present invention was achieved by finding such a phenomenon. In addition, the self contraction of the tissue can be regulated by culturing the tissue in a suspended manner. Therefore, it is possible to regulate the three-dimensional shape of the tissue. The present invention also provides a method for producing an implantable synthetic tissue which does not require a plurality of monolayer cell sheets assembled to form a three-dimensionally structured synthetic tissue. The present invention is characterized by richness in adhesion molecules, nonnecessity of additional fixation at an implantation site, and good biological integration.

    摘要翻译: 本发明可用于没有支架的实际植入手术。 本发明提供可通过培养产生并具有高水平分化能力的合成组织或复合物。 本发明还提供了使用替换和覆盖来修复和/或再生组织的治疗和药物。 通过在特定培养条件下培养细胞,使得培养基含有细胞外基质合成促进剂,细胞被组织并容易从培养皿中分离。 本发明是通过发现这种现象来实现的。 此外,可以通过以悬浮方式培养组织来调节组织的自收缩。 因此,可以调节组织的三维形状。 本发明还提供了一种用于生产可植入的合成组织的方法,其不需要组装成多个单层细胞片以形成三维结构的合成组织。 本发明的特征在于粘附分子的丰富性,植入部位的附加固定的不必要性以及良好的生物整合性。

    Composite devices of laminate type and processes
    73.
    发明授权
    Composite devices of laminate type and processes 失效
    复合装置的层压型和工艺

    公开(公告)号:US07205650B2

    公开(公告)日:2007-04-17

    申请号:US10073117

    申请日:2002-02-12

    IPC分类号: H01L23/06

    摘要: In a composite device of the laminate type having a laminate structure of a composite ceramic layer and a dielectric ceramic layer, the composite ceramic layer including a layer portion having the same composition as the dielectric ceramic layer and a plurality of particle portions formed on the surface of the layer portion. The particle portions are made from magnetic ceramic material. This prevents the ceramic layers of the device from cracking and separating when fired.

    摘要翻译: 在具有复合陶瓷层和电介质陶瓷层的叠层结构的叠层型复合装置中,复合陶瓷层包括具有与介电陶瓷层相同组成的层部分和形成在表面上的多个颗粒部分 的层部分。 颗粒部分由磁性陶瓷材料制成。 这样可防止器件的陶瓷层在烧制时开裂和分离。

    Ultrasonic motion detecting device, and image producing device and ultrasonic therapeutic using the detecting device
    74.
    发明申请
    Ultrasonic motion detecting device, and image producing device and ultrasonic therapeutic using the detecting device 失效
    超声波运动检测装置,以及使用该检测装置的图像生成装置和超声治疗装置

    公开(公告)号:US20070078326A1

    公开(公告)日:2007-04-05

    申请号:US10583033

    申请日:2004-11-16

    IPC分类号: A61B5/05

    CPC分类号: A61B8/08

    摘要: There is provided a ultrasonic motion detecting device that detects a three-dimensional motion of an object. The ultrasonic motion detecting device, comprises first and second ultrasonic transducers 13 having piezoelectric elements arranged in an array, which transmit ultrasonic waves to an object and acquire reflection signals from the object, a motion detection unit 20 that extracts an estimation region which is used for estimating a motion of the object from the reflection signals that are acquired by the first and second ultrasonic transducers, and detects a three-dimensional motion within the estimation region; and an image display unit 19 that displays the three-dimensional motion within the estimation region, wherein ultrasonic wave scanning surfaces due to the first and second ultrasonic transducers cross over each other.

    摘要翻译: 提供了一种检测物体的三维运动的超声波运动检测装置。 超声波运动检测装置包括具有排列成阵列的压电元件的第一和第二超声波换能器13,其将超声波向对象发送并从物体获取反射信号;运动检测单元20,其提取用于 根据由第一和第二超声换能器获取的反射信号估计物体的运动,并检测估计区域内的三维运动; 以及在估计区域内显示三维运动的图像显示单元19,其中由于第一和第二超声波换能器而引起的超声波扫描表面彼此交叉。

    Decoy composition for treating and preventing inflammatory disease
    75.
    发明申请
    Decoy composition for treating and preventing inflammatory disease 审中-公开
    用于治疗和预防炎性疾病的诱饵组合物

    公开(公告)号:US20060241066A1

    公开(公告)日:2006-10-26

    申请号:US10516208

    申请日:2003-05-20

    IPC分类号: A61K48/00 A61K9/127

    摘要: It is intended to efficiently treat an inflammatory disease without causing side effects. This object can be achieved by providing a medicinal composition for treating and preventing an inflammatory disease and disorders, and disorders caused by the disease and disorders which contains at least one decoy of NF-κB or an analogous transcriptional factor and a pharmaceutically acceptable carrier; and a method of treating and preventing an inflammatory disease and disorders, and disorders caused by the disease and disorders which comprises the step of administering to a patient a composition containing at least one decoy of NF-κB or an analogous transcriptional factor and a pharmaceutically acceptable carrier.

    摘要翻译: 旨在有效地治疗炎性疾病而不引起副作用。 该目的可以通过提供一种用于治疗和预防炎性疾病和病症的药物组合物,以及由包含至少一种NF-κB诱变物或类似转录因子和药学上可接受的载体的疾病和病症引起的疾病, 以及治疗和预防炎性疾病和病症以及由疾病和病症引起的疾病的方法,其包括向患者施用含有至少一种NF-κB诱变物或类似转录因子和药学上可接受的组合物的步骤 载体

    Panoramic radiographic apparatus and digital sensor cassette used for same apparatus
    78.
    发明授权
    Panoramic radiographic apparatus and digital sensor cassette used for same apparatus 失效
    用于同一设备的全景放射线照相设备和数字传感器盒

    公开(公告)号:US06173035B2

    公开(公告)日:2001-01-09

    申请号:US09154674

    申请日:1998-09-18

    IPC分类号: A61B602

    CPC分类号: A61B6/4233 A61B6/14 A61B6/548

    摘要: The panoramic radiographic apparatus of the present invention has a cassette holder capable of accommodating both a conventional film cassette and a digital sensor cassette loaded with an electric X-ray image detector, one at a time, in a rotary arm, wherein when a film cassette is mounted, the cassette holder is mechanically moved in accordance with the rotation of the rotary arm so as to carry out panoramic radiographing, and when a digital sensor cassette is mounted, without moving the cassette holder, the electric X-ray image detector is driven by supplying control signals corresponding to the rotation of the rotary arm to the digital sensor cassette to obtain image signals required for generating a panoramic X-ray image. Therefore, both the film cassette and the digital sensor cassette can easily be mounted, one at a time, whereby required panoramic X-ray images can be obtained by fully using the features of each type of cassette.

    摘要翻译: 本发明的全景放射线照相设备具有盒式磁带保持器,其能够在旋转臂中一次一个地容纳传统的胶片盒和装有电X射线图像检测器的数字传感器盒,其中当胶片盒 安装盒式磁带架,根据旋转臂的旋转机械地移动,以进行全景放射照相,并且当安装数字传感器盒而不移动盒式磁带架时,驱动电X射线图像检测器 通过将对应于旋转臂的旋转的控制信号提供给数字传感器盒,以获得产生全景X射线图像所需的图像信号。 因此,可以容易地一次一个地安装胶卷盒和数字传感器盒,从而通过充分利用每种类型的盒的特征可以获得所需的全景X射线图像。

    Composite magnetic head having accurately aligned gaps
    80.
    发明授权
    Composite magnetic head having accurately aligned gaps 失效
    复合磁头具有准确对准的间隙

    公开(公告)号:US4719527A

    公开(公告)日:1988-01-12

    申请号:US793007

    申请日:1985-10-30

    摘要: A magnetic head which comprises a pair of head chips each composed of a pair of plate-like magnetic cores superposed on and joined to each other with a spacer interposed therebetween and having a gap at the junction, a pair of base plates joined to the pair of head chips individually and positioned on opposite sides of and in parallel to a plane containing the gaps, each of the magnetic core having at one end thereof a head with a small width substantially equal to the width of tracks and an end portion of increased width opposite to the head, a shield member interposed between the head chips at the head portions, a stud portion provided on at least one of the pair of magnetic cores and projecting toward the other core, and a coil provided around the stud portion. A process is also disclosed for producing such magnetic heads wherein the pair of magnetic cores are positioned close to each other, and the gaps are accurately positioned on the same plane.

    摘要翻译: 一种磁头,包括一对磁头芯片,每个磁头芯片由叠置在一起的一对板状磁芯组成,并且隔着间隔件插入并且在连接处具有间隙,一对连接到该对的基板 的头芯片分别定位在与包含间隙的平面的相对侧并且平行于其平面,每个磁芯的一端具有基本上等于轨道的宽度的小宽度的头部和具有增加的宽度的端部 位于头部相对的屏蔽部件之间,插入在头部的头部芯片之间的屏蔽部件,设置在一对磁芯中的至少一个并朝向另一个芯部突出的螺柱部分,以及设置在螺柱部分周围的线圈。 还公开了一种用于制造这种磁头的方法,其中一对磁芯彼此靠近定位,并且间隙被精确地定位在同一平面上。