公开(公告)号：US08547549B2

公开(公告)日：2013-10-01

申请号：US13129571

申请日：2008-11-17

Applicant: Huei Pei Kuo ,  Jing Tang ,  Fung Suong Ou ,  Zhiyong Li ,  Shih-Yuan Wang

Inventor： Huei Pei Kuo ,  Jing Tang ,  Fung Suong Ou ,  Zhiyong Li ,  Shih-Yuan Wang

IPC: G01J3/44 ,  G01N21/65

CPC classification number: B82Y20/00 ,  G01N21/658

Abstract: A substrate for Surface Enhanced Raman Scattering (SERS). The substrate comprises at least one nanostructure protruding from a surface of the substrate and a SERS active metal over the at least one nanostructure, wherein the SERS active metal substantially covers the at least one nanostructure and the SERS active metal creates a textured layer on the at least one nanostructure.

Abstract translation: 用于表面增强拉曼散射的衬底（SERS）。 衬底包括从衬底的表面突出的至少一个纳米结构和在至少一个纳米结构上的SERS活性金属，其中SERS活性金属基本上覆盖至少一个纳米结构，并且SERS活性金属在其上形成纹理化层 至少一个纳米结构。

公开(公告)号：US20120300202A1

公开(公告)日：2012-11-29

申请号：US13383385

申请日：2009-07-22

Applicant: David A. Fattal ,  Jingjing Li ,  Zhiyong Li ,  Shih-Yuan Wang

Inventor： David A. Fattal ,  Jingjing Li ,  Zhiyong Li ,  Shih-Yuan Wang

IPC: G01J3/44 ,  B82Y15/00

CPC classification number: G01N21/658

Abstract: An autonomous light amplifying device for surface enhanced Raman spectroscopy includes a dielectric layer, at least one laser cavity defined by at least one light confining mechanism formed in the dielectric layer, at least one nano-antenna established on the dielectric layer in proximity to the at least one laser cavity, and a gain region positioned in the dielectric layer or adjacent to the dielectric layer.

Abstract translation: 用于表面增强拉曼光谱的自主光放大装置包括电介质层，至少一个激光腔，其由形成在电介质层中的至少一个限光机构限定，至少一个在电介质层上建立的纳米天线邻近于 至少一个激光腔，以及位于所述介电层中或与所述电介质层相邻的增益区。

公开(公告)号：US20120113420A1

公开(公告)日：2012-05-10

申请号：US13384456

申请日：2009-09-17

Applicant: Huei Pei Kuo ,  Shih-Yuan Wang ,  Min Hu ,  Zhiyong Li ,  Alexander M. Bratkovski

Inventor： Huei Pei Kuo ,  Shih-Yuan Wang ,  Min Hu ,  Zhiyong Li ,  Alexander M. Bratkovski

IPC: G01J3/44

CPC classification number: G01N21/658 ,  B82Y15/00 ,  B82Y30/00

Abstract: An electrically driven device (10) for surface enhanced Raman spectroscopy includes a first electrode (16), a substrate (12) positioned proximate to the first electrode (16), a plurality of cone shaped protrusions (12′) formed integrally with or on a substrate surface (S), a Raman signal-enhancing material (14) coated on each protrusion (12′), and a second electrode (18) positioned relative to the first electrode (16) at a predetermined distance, D. Each of the protrusions (12′) has a tip (22) with a radius of curvature, r, ranging from about 0.1 nm to about 100 nm. The second electrode (18) is positioned relative to the first electrode (16) such that the electrodes (16, 18) together produce an electric field (EF) when a voltage bias is applied therebetween. The electric field (EF) has a field distribution that creates a stronger field gradient at a region proximate to the tips (22) than at other portions of the substrate (12).

Abstract translation: 用于表面增强拉曼光谱的电驱动装置（10）包括第一电极（16），靠近第一电极（16）定位的基板（12），与该第一电极（16）一体形成的多个锥形突起 涂覆在每个突起（12'）上的衬底表面（S），拉曼信号增强材料（14）和相对于第一电极（16）以预定距离D定位的第二电极（D）。 突起（12'）具有从约0.1nm至约100nm范围内的具有曲率半径r的尖端（22）。 第二电极（18）相对于第一电极（16）定位，使得当施加电压时，电极（16,18）一起产生电场（EF）。 电场（EF）具有在靠近尖端（22）的区域处比在衬底（12）的其它部分处产生更强的场梯度的场分布。

公开(公告)号：US20120107569A1

公开(公告)日：2012-05-03

申请号：US12916239

申请日：2010-10-29

Applicant: Michael Josef Stuke ,  Zhiyong Li ,  Shih-Yuan Wang ,  Fung Suong Ou ,  Min Hu ,  Wei Wu ,  Lars Helge Thylen

Inventor： Michael Josef Stuke ,  Zhiyong Li ,  Shih-Yuan Wang ,  Fung Suong Ou ,  Min Hu ,  Wei Wu ,  Lars Helge Thylen

IPC: B32B3/30 ,  B05D3/06 ,  B05D3/02 ,  B05D1/36 ,  B05D3/00

CPC classification number: G01N21/658 ,  B81B3/0005 ,  Y10T428/24355 ,  Y10T428/24612

Abstract: A device for Surface Enhanced Raman Scattering (SERS). The device includes a plurality of nanostructures protruding from a surface of a substrate, a SERS active metal disposed on a portion of said plurality of nanostructures, and a low friction film disposed over the plurality of nanostructures and the SERS active metal. The low friction film is to prevent adhesion between the plurality of nanostructures.

Abstract translation: 用于表面增强拉曼散射（SERS）的器件。 该装置包括从衬底表面突出的多个纳米结构，设置在所述多个纳米结构的一部分上的SERS活性金属，以及设置在多个纳米结构和SERS活性金属上的低摩擦膜。 低摩擦膜是为了防止多个纳米结构之间的粘附。

公开(公告)号：US20080180662A1

公开(公告)日：2008-07-31

申请号：US11701045

申请日：2007-01-31

Applicant: Shih-Yuan Wang ,  Zhiyong Li

Inventor： Shih-Yuan Wang ,  Zhiyong Li

IPC: G01J3/44

CPC classification number: G01J3/44 ,  G01N21/658

Abstract: Raman systems include a radiation source, a radiation detector configured to detect Raman scattered radiation, and a Raman signal-enhancing structure. The Raman signal-enhancing structure includes a first layer of Raman signal-enhancing material, a substantially monomolecular layer of molecules disposed on at least a portion of the first layer of Raman signal-enhancing material, and a second layer of Raman signal-enhancing material disposed on at least a portion of the substantially monomolecular layer of molecules. The second layer of Raman signal-enhancing material is disposed on a side of the layer of molecules opposite the first layer of Raman signal-enhancing material. Methods of performing Raman spectroscopy include providing such a Raman signal-enhancing structure, providing an analyte on the Raman signal-enhancing structure, irradiating the analyte and the structure, and detecting Raman scattered radiation.

Abstract translation: 拉曼系统包括辐射源，被配置为检测拉曼散射辐射的辐射检测器和拉曼信号增强结构。 拉曼信号增强结构包括第一层拉曼信号增强材料，设置在第一层拉曼信号增强材料的至少一部分上的基本上单分子层的分子，以及第二层拉曼信号增强材料 设置在分子的基本单分子层的至少一部分上。 第二层拉曼信号增强材料设置在与第一层拉曼信号增强材料相对的分子层的一侧。 执行拉曼光谱的方法包括提供这样的拉曼信号增强结构，在拉曼信号增强结构上提供分析物，照射分析物和结构，以及检测拉曼散射辐射。

公开(公告)号：US07321422B2

公开(公告)日：2008-01-22

申请号：US10942482

申请日：2004-09-16

Applicant: Zhiyong Li ,  Shih-Yuan Wang

Inventor： Zhiyong Li ,  Shih-Yuan Wang

IPC: G01J3/44

CPC classification number: G01N21/658

Abstract: SERS-active structures including features having nanoscale dimensions are disclosed, including methods for forming such SERS-active structures and methods for forming a plurality of such SERS-active structures. Methods for performing SERS using SERS-active structures also are disclosed.

Abstract translation: 公开了包括具有纳米级尺寸的特征的SERS活性结构，包括形成这种SERS-活性结构的方法和形成多个这样的SERS-活性结构的方法。 还公开了使用SERS活性结构来执行SERS的方法。

公开(公告)号：US20070252982A1

公开(公告)日：2007-11-01

申请号：US11413910

申请日：2006-04-28

Applicant: Shih-Yuan Wang ,  R. Williams ,  Raymond Beausoleil ,  Theodore Kamins ,  Zhiyong Li ,  Wei Wu

Inventor： Shih-Yuan Wang ,  R. Williams ,  Raymond Beausoleil ,  Theodore Kamins ,  Zhiyong Li ,  Wei Wu

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/658 ,  G01J3/44

Abstract: Raman systems include a radiation source, a radiation detector, and a Raman device or signal-enhancing structure. Raman devices include a tunable resonant cavity and a Raman signal-enhancing structure coupled to the cavity. The cavity includes a first reflective member, a second reflective member, and an electro-optic material disposed between the reflective members. The electro-optic material exhibits a refractive index that varies in response to an applied electrical field. Raman signal-enhancing structures include a substantially planar layer of Raman signal-enhancing material having a major surface, a support structure extending from the major surface, and a substantially planar member comprising a Raman signal-enhancing material disposed on an end of the support structure opposite the layer of Raman signal-enhancing material. The support structure separates at least a portion of the planar member from the layer of Raman signal-enhancing material by a selected distance of less than about fifty nanometers.

Abstract translation: 拉曼系统包括辐射源，辐射检测器和拉曼器件或信号增强结构。 拉曼器件包括耦合到空腔的可调谐谐振腔和拉曼信号增强结构。 空腔包括第一反射构件，第二反射构件和设置在反射构件之间的电光材料。 电光材料表现出响应于所施加的电场而变化的折射率。 拉曼信号增强结构包括具有主表面的基本平坦的拉曼信号增强材料层，从主表面延伸的支撑结构和包括设置在支撑结构的端部上的拉曼信号增强材料的基本上平面的构件 与拉曼信号增强材料层相对。 支撑结构将平面构件的至少一部分与拉曼信号增强材料层分开小于约五十纳米的选定距离。

公开(公告)号：US20070035717A1

公开(公告)日：2007-02-15

申请号：US11580621

申请日：2006-10-13

Applicant: Wei Wu ,  Shih-Yuan Wang ,  Zhiyong Li ,  Robert Walmsley

Inventor： Wei Wu ,  Shih-Yuan Wang ,  Zhiyong Li ,  Robert Walmsley

IPC: G03B27/02

CPC classification number: G03F7/0002 ,  B82Y10/00 ,  B82Y40/00 ,  G03F7/7035

Abstract: A contact lithography system includes a patterning tool bearing a pattern; a substrate chuck for chucking a substrate to receive the pattern from the patterning tool; where the system deflects a portion of either the patterning tool or the substrate to bring the patterning tool and a portion of the substrate into contact; and a stepper for repositioning either or both of the patterning tool and substrate to align the pattern with an additional portion of the substrate to also receive the pattern. A method of performing contact lithography comprising: deflecting a portion of either a patterning tool or a substrate to bring the patterning tool and a portion of the substrate into contact; and repositioning either or both of the patterning tool and substrate to align a pattern on the patterning tool with an additional portion of the substrate to also receive the pattern.

Abstract translation: 接触光刻系统包括具有图案的图案形成工具; 用于夹持基板以从图案形成工具接收图案的基板卡盘; 其中所述系统使所述图案化工具或所述衬底的一部分偏转以使所述图案形成工具和所述衬底的一部分接触; 以及步进器，用于重新定位图案形成工具和衬底中的一个或两个，以使图案与衬底的附加部分对准以也接收图案。 一种执行接触光刻的方法，包括：使图案形成工具或衬底的一部分偏转以使所述图案化工具和所述衬底的一部分接触; 以及重新定位所述图案形成工具和衬底中的一个或两个，以将所述图案形成工具上的图案与所述衬底的附加部分对准以也接收所述图案。

公开(公告)号：US07177021B2

公开(公告)日：2007-02-13

申请号：US10942004

申请日：2004-09-14

Applicant: Shih-Yuan Wang ,  M. Saif Islam ,  Zhiyong Li

Inventor： Shih-Yuan Wang ,  M. Saif Islam ,  Zhiyong Li

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/658 ,  G01J3/10 ,  G01N21/774 ,  H01S3/1086 ,  H01S3/169 ,  H01S5/026 ,  H01S5/1021 ,  H01S5/183 ,  H01S5/423

Abstract: Integrated radiation source/amplifying structures for use in surface enhanced Raman spectroscopy (SERS) and hyper-SERS are disclosed. The structures include a radiation source integrated with a SERS-active structure that is provided within a resonant cavity. SERS and hyper-SERS systems employing the integrated radiation source/amplifying structures are disclosed. Methods of performing SERS and hyper-SERS are also disclosed.

Abstract translation: 公开了用于表面增强拉曼光谱（SERS）和超SERS的集成放射源/放大结构。 该结构包括与设置在谐振腔内的SERS-活性结构集成的辐射源。 公开了采用集成放射源/放大结构的SERS和超SERS系统。 还公开了执行SERS和超SERS的方法。

公开(公告)号：US20060164636A1

公开(公告)日：2006-07-27

申请号：US11044676

申请日：2005-01-27

Applicant: M. Islam ,  Shih-Yuan Wang ,  Wei Wu ,  Zhiyong Li ,  R. Williams

Inventor： M. Islam ,  Shih-Yuan Wang ,  Wei Wu ,  Zhiyong Li ,  R. Williams

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/658 ,  G01J3/44 ,  H01L31/02325 ,  H01L31/105

Abstract: Devices, systems, and methods for enhancing Raman spectroscopy and hyper-Raman are disclosed. A molecular analysis device for performing Raman spectroscopy comprises a substrate and a laser source disposed on the substrate. The laser source may be configured for emanating a laser radiation, which may irradiate an analyte disposed on a Raman enhancement structure. The Raman enhancement structure may be disposed on the substrate or apart from the substrate. The molecular analysis device also include a radiation receiver disposed on the substrate and configured for receiving a Raman scattered radiation, which may be generated by the irradiation of the analyte and Raman enhancement structure.

Abstract translation: 公开了用于增强拉曼光谱和超拉曼的装置，系统和方法。 用于执行拉曼光谱的分子分析装置包括设置在基板上的基板和激光源。 激光源可以被配置为发射激光辐射，其可照射设置在拉曼增强结构上的分析物。 拉曼增强结构可以设置在基板上或者离开基板。 分子分析装置还包括设置在基板上并被配置为用于接收可以通过分析物的照射和拉曼增强结构产生的拉曼散射辐射的辐射接收器。