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    Anti-bacterial agents and their use in therapy
    73.
    发明授权
    Anti-bacterial agents and their use in therapy 有权

    公开(公告)号：US10570180B2

    公开(公告)日：2020-02-25

    申请号：US15570837

    申请日：2016-05-06

    Applicant: Norwegian University of Science and Technology (NTNU)

    Inventor： Marit Otterlei ,  Siri Bachke

    IPC: A01N37/18 ,  A61K38/00 ,  A61P31/04 ,  A61K38/08 ,  A61K38/04 ,  C07K5/00 ,  C07K7/00 ,  C07K16/00 ,  C07K17/00 ,  C07K14/00 ,  A61K38/17 ,  C07K14/47 ,  A61K47/50 ,  A61L9/20 ,  A61L27/22 ,  C12N5/078

    Abstract: The present invention provides an agent, or a composition containing an agent, for use in treating or preventing a bacterial infection in a subject, wherein said agent comprises: (i) an oligopeptidic compound comprising a PCNA interacting motif and a domain that facilitates the cellular uptake of said compound, wherein the PCNA interacting motif is X1X2X3X4X5X6 (SEQ ID NO: 1) and wherein: X1 is a basic amino acid; X2 is an aromatic amino acid; X3 is an aromatic amino acid or a hydrophobic amino acid that has an R group comprising at least three carbon atoms; X4 is an uncharged amino acid other than an aromatic amino acid, Glycine (G) and Proline (P); X5 is any amino acid other than an acidic amino acid or an aromatic amino acid; and X6 is any amino acid other than an acidic amino acid or an aromatic amino acid, preferably a basic amino acid or Proline (P), wherein when X3 is not an aromatic amino acid, X5 is not lysine (K) and X6 is a basic amino acid or Proline (P); or (ii) a nucleic acid molecule comprising a sequence encoding the oligopeptidic compound of (i). In certain aspects the agent and composition of the invention may be used as single agents. In other aspects of the invention the agents and composition may be used in conjunction with one or more addition active agents, such as antibiotics, or in combination with UV radiation.

    Solar cells
    75.
    发明授权
    Solar cells 有权

    公开(公告)号：US10347781B2

    公开(公告)日：2019-07-09

    申请号：US14409837

    申请日：2013-06-21

    Applicant: NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU)

    Inventor： Helge Weman ,  Bjørn-Ove Fimland ,  Dong Chul Kim

    IPC: H01L31/18 ,  H01L31/0224 ,  H01L31/0304 ,  H01L31/0352

    Abstract: A composition of matter, in particular a photovoltaic cell, comprising: at least one core semiconductor nanowire on a graphitic substrate, said at least one core nanowire having been grown epitaxially on said substrate wherein said nanowire comprises at least one group III-V compound or at least one group II-VI compound or at least one group IV element; a semiconductor shell surrounding said core nanowire, said shell comprising at least one group III-V compound or at least one group II-VI compound or at least one group IV element such that said core nanowire and said shell form a n-type semiconductor and a p-type semiconductor respectively or vice versa; and an outer conducting coating surrounding said shell which forms an electrode contact.

    Systematic coding technique
    77.
    发明授权
    Systematic coding technique 有权

    公开(公告)号：US09430443B1

    公开(公告)日：2016-08-30

    申请号：US14707211

    申请日：2015-05-08

    Applicant: Norwegian University of Science and Technology

    Inventor： Rune Erlend Jensen ,  Katina Kralevska ,  Danilo Gligoroski ,  Sindre Berg Stene

    IPC: G06F17/16 ,  H03M13/11

    CPC classification number: H03M13/1174 ,  H03M13/033 ,  H03M13/134 ,  H03M13/373 ,  H03M13/6502

    Abstract: Disclosed herein is a method of generating a generator matrix for defining how to systematically code source data, the method comprising: determining source nodes for comprising a plurality of sub-stripes of source data, wherein the number of source nodes is K and the number of sub-stripes of source data comprised by each source node is S; determining redundant nodes for comprising a plurality of sub-stripes of coded data, wherein the number of redundant nodes is R and the number of sub-stripes of coded data comprised by each redundant node is S; determining values of a first generator matrix according to a systematic coding technique such that K of the rows of the generator matrix to define how to generate all of the K source nodes as comprising source data and R of the rows of the first generator matrix define how to generate all of the R redundant nodes as comprising combinations of two or more of the source nodes; generating a second generator matrix, with a first dimension (K×S) and a second dimension ((K+R)×S), in dependence on the determined first generator matrix, wherein each value of the second generator matrix defines how to generate the data comprised by a respective sub-stripe of a node defined by the first generator matrix such that the values of the second generator matrix define how to generate all of the sub-stripes of all of the nodes defined by the first generator matrix; and changing one or more of the values of the second generator matrix so that a sub-stripe of at least one of the redundant nodes is defined, by the systematic coding technique, as being dependent on a combination of two or more sub-stripes of data in the source nodes and is further defined as being dependent on one or more further sub-stripes of data, in a respective one or more source nodes, that the sub-stripe of the redundant node was not defined as being dependent on by the systematic coding technique. Advantageously, when the second generator matrix is used to generate erasure coded data in a data storage system, the amount of data that needs to be obtained to reconstruct a lost data node is less than if Reed-Solomon or other known coding techniques had been used.

    METHODS AND DEVICES FOR ESTIMATING BLOOD FLOW CHARACTERISTICS
    78.
    发明申请
    METHODS AND DEVICES FOR ESTIMATING BLOOD FLOW CHARACTERISTICS 审中-公开
    用于估计血液流动特性的方法和装置

    公开(公告)号：US20090043208A1

    公开(公告)日：2009-02-12

    申请号：US11836919

    申请日：2007-08-10

    Applicant: Torbjorn Hergum ,  Hans Garman Torp

    Inventor： Torbjorn Hergum ,  Hans Garman Torp

    IPC: A61B8/06

    CPC classification number: A61B8/065 ,  A61B8/0883 ,  G01F1/663 ,  G01S7/52071 ,  G01S15/8981

    Abstract: Methods and devices are described for estimating blood flow characteristics through an orifice of a subject, such as regurgitant blood flow through a faulty heart valve. Acoustical techniques can be applied to send bursts of energy, such as high repetition pulsed ultrasonic signals, to a sample volume in a region of interest. For example, multiple beams can be formed from the bursts of energy each having a cross sectional area that is smaller than the cross sectional area of the orifice being investigated. By combining the multiple beams, a composite measure of the blood flow characteristics through the orifice can be obtained. In one example, the composite measure can provide an estimate of the cross sectional area of the interrogated orifice. The composite measure can also provide an estimate of the geometry of the orifice. Systems and components for providing such composite measures are also disclosed.

    Abstract translation: 描述了用于估计通过受试者的孔的血流特性的方法和装置，例如通过故障心脏瓣膜的反流血流。 可以应用声学技术将诸如高重复脉冲超声波信号的能量脉冲发射到感兴趣区域中的样本体积。 例如，可以从每个具有小于被研究的孔的横截面面积的横截面积的能量脉冲串形成多个光束。 通过组合多个梁，可以获得通过孔的血流特性的综合测量。 在一个示例中，复合测量可以提供询问孔的横截面面积的估计。 复合测量还可以提供孔的几何形状的估计。 还公开了用于提供这种复合措施的系统和部件。

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