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    Antimicrobial Composition and Use as Food Treatment
    72.
    发明申请
    Antimicrobial Composition and Use as Food Treatment 有权
    抗菌成分及用作食物处理

    公开(公告)号：US20120148716A1

    公开(公告)日：2012-06-14

    申请号：US13363455

    申请日：2012-02-01

    申请人： Michael P. Doyle ,  Tong Zhao

    发明人： Michael P. Doyle ,  Tong Zhao

    IPC分类号： A01N37/02 ,  A01P1/00 ,  A23B4/18 ,  A23L3/3454 ,  B65B55/00

    CPC分类号： A23L3/3508 ,  A01N37/02 ,  A01N37/36 ,  A01N37/42 ,  A23L3/3463 ,  A01N25/04 ,  A01N2300/00 ,  A01N25/30 ,  A01N41/02

    摘要： Antimicrobial compositions are provided comprising a pharmaceutically acceptable organic acid and a pharmaceutically acceptable surfactant. This synergistic combination allows compositions to be formulated at low concentrations that have efficacy in reducing bacterial counts by greater than 3 log within 5 minutes of contact while preserving the organoleptic properties of treated foods, including fresh produce. Also provided are methods for the use of the compositions to reduce the microbial load on the surfaces of foodstuffs, processed food products, and the hard surfaces of food preparation machinery, tools, benches, and the like.

    摘要翻译： 提供了包含药学上可接受的有机酸和药学上可接受的表面活性剂的抗微生物组合物。 这种协同组合允许组合物以低浓度配制，其具有在接触5分钟内减少细菌计数大于3log的功效，同时保持经处理的食物（包括新鲜产品）的感官特性。 还提供了使用组合物减少食品，加工食品和食品制备机械，工具，长凳等的表面上的微生物负荷的方法。

    Chlorine-Free Liquid Microbicide Treatment
    73.
    发明申请
    Chlorine-Free Liquid Microbicide Treatment 审中-公开
    无氯液体杀菌剂处理

    公开(公告)号：US20120129928A1

    公开(公告)日：2012-05-24

    申请号：US13351477

    申请日：2012-01-17

    申请人： Michael P. Doyle ,  Tong Zhao

    发明人： Michael P. Doyle ,  Tong Zhao

    IPC分类号： A01N41/04 ,  A01P1/00

    CPC分类号： A23L2/44 ,  A01N37/42 ,  A23L3/3508 ,  A23L3/3535 ,  A01N25/02 ,  A01N25/30 ,  A01N41/02 ,  A01N2300/00

    摘要： The combination of the surfactant SDS with levulinic acid produces a synergistic effect in relation to the antimicrobial effectiveness of the individual compounds. Accordingly, this surprising synergy allows the formulation of compositions wherein the active agents are present at concentrations effective to reduce bacterial counts in liquids, including, but not limited to, water and other beverages, especially those having a pH value less than about 7.0 by a factor between 103 and 107 without altering the organoleptic properties of the treated food substance. The active agents are FDA-approved as food additives, and the treated beverages can be any aqueous-based beverage consumable by humans or animals.

    摘要翻译： 表面活性剂SDS与乙酰丙酸的组合与单个化合物的抗微生物效力相关产生协同效应。 因此，这种惊人的协同作用允许组合物的配制，其中活性剂以有效降低液体中细菌计数的浓度存在，包括但不限于水和其它饮料，特别是pH值小于约7.0的那些 因子在103和107之间，而不改变处理过的食物的感官特性。 活性剂经FDA批准作为食品添加剂，经处理的饮料可以是人或动物消耗的任何水性饮料。

    CHLORINE-FREE WATER TREATMENT
    77.
    发明申请
    CHLORINE-FREE WATER TREATMENT 审中-公开
    无氯水处理

    公开(公告)号：US20120071553A1

    公开(公告)日：2012-03-22

    申请号：US13234286

    申请日：2011-09-16

    申请人： Michael P. Doyle ,  Tong Zhao

    发明人： Michael P. Doyle ,  Tong Zhao

    IPC分类号： A01N41/04 ,  A01P1/00 ,  A23L2/44

    CPC分类号： A23L2/44 ,  A01N37/42 ,  A01N41/02 ,  A23F3/163 ,  A23L3/3508 ,  A23L3/3535 ,  A01N25/30 ,  A01N2300/00 ,  A01N37/02 ,  A01N37/36

    摘要： A combination of the surfactant SDS with levulinic acid produces a synergistic effect in relation to the antimicrobial effectiveness of the individual compounds, allowing the formulation of compositions wherein the active agents are present at concentrations effective to reduce bacterial and fungal counts in liquids, including, but not limited to, water and other beverages, without altering the organoleptic properties of the treated food substance. The active agents are FDA-approved as food additives, and the treated beverages can be any aqueous-based beverage consumable by humans or animals. The levulinic acid-SDS combination is also suitable for reducing or eliminating the microbial population on the surfaces of water and beverage containers, and the machinery and facilities for the bottling of liquids.

    摘要翻译： 表面活性剂SDS与乙酰丙酸的组合与单独化合物的抗微生物效力相关产生协同效应，允许组合物的配制，其中活性剂以有效降低液体中的细菌和真菌计数的浓度存在，包括但不限于 不限于水和其他饮料，而不改变处理过的食物的感官特性。 活性剂经FDA批准作为食品添加剂，经处理的饮料可以是人或动物消耗的任何水性饮料。 乙酰丙酸 - SDS组合也适用于减少或消除水和饮料容器表面的微生物群体，以及用于装瓶液体的机器和设施。

    Tablet composition for the in-situ generation of chlorine dioxide for use in antimicrobial applications
    80.
    发明授权
    Tablet composition for the in-situ generation of chlorine dioxide for use in antimicrobial applications 失效
    用于原位生成用于抗微生物应用的二氧化氯的片剂组合物

    公开(公告)号：US08017032B2

    公开(公告)日：2011-09-13

    申请号：US12806964

    申请日：2010-08-25

    申请人： Roy W. Martin

    发明人： Roy W. Martin

    IPC分类号： C01B11/10 ,  C01B11/02 ,  C11D3/395 ,  A01N25/34 ,  A61K9/30

    CPC分类号： C02F1/76 ,  A01N37/42 ,  A01N59/00 ,  C01B11/024 ,  C02F1/688 ,  C02F2103/023 ,  A01N59/02 ,  A01N43/64 ,  A01N43/50 ,  A01N25/34 ,  A01N25/04 ,  A01N2300/00

    摘要： A solid composition in the form of a tablet that generates and releases a biocidal solution comprising at least chlorine dioxide with an enhanced weight percent yield is presented. The composition comprises reactants capable of in-situ generation of chlorine dioxide comprising a chlorite donor that is coated with a gel-forming material that slows the rate of dissolution of the high solubility chlorite donor, a free halogen donor, and an acid source, resulting in an unexpectedly high weight percent yield and providing a controlled release of biocidal solution. The compositions of the invention show improved environmental stability which can reduce the cost of packaging and significantly increase the utility of the composition. The controlled release allows the use in multi-tablet chemical dispensers which may otherwise induce potentially explosive conditions or allow rapid release of the biocidal solution thereby inducing a spike in chemical concentration rather than a controlled and sustained release.

    摘要翻译： 呈现了片剂形式的固体组合物，其产生并释放至少包含二氧化氯至少具有提高的重量百分比产率的杀生物溶液。 该组合物包含能够原位产生二氧化氯的反应物，其包含用形成凝胶的材料涂覆的亚氯酸盐供体，其减缓高溶解度亚氯酸盐供体，游离卤素供体和酸源的溶解速率，从而得到 以意想不到的高重量百分比产率并提供杀菌溶液的控制释放。 本发明的组合物显示改善的环境稳定性，其可以降低包装成本并显着提高组合物的效用。 受控释放允许在多片剂化学分配器中使用，否则可能引起潜在的爆炸性条件或允许杀生物溶液的快速释放，从而诱导化学浓度的尖峰而不是受控和持续的释放。