公开(公告)号：US07812323B2

公开(公告)日：2010-10-12

申请号：US12159433

申请日：2007-01-05

申请人： Paul Leslie Burn ,  Ifor David William Samuel ,  Homar Barcena

发明人： Paul Leslie Burn ,  Ifor David William Samuel ,  Homar Barcena

IPC分类号： G01J1/58 ,  C09K11/06

CPC分类号： C09K11/06 ,  C08G83/002 ,  C09K2211/14 ,  C09K2211/1416 ,  C09K2211/1425 ,  G01N33/0057

摘要： The invention provides sensors comprising one or more compounds of formulae (I) and (II): [DENDRON1]p-CORE-[[X]r-[DENDRON]m]n  (I) [DENDRON1]p-[X]r-[DENDRON]q  (II) wherein CORE, X, DENDRON, DENDRON1, m, n, p, q and r are as defined herein. The optical (e.g. luminescent) and electronic properties of the compounds are capable of being altered by exposure to a number of different substances. The invention also provides the use of the compounds disclosed above in the sensing of substances, in particular explosives.

摘要翻译： 本发明提供了包含一种或多种式（I）和（II）化合物的传感器：[DENDRON1]对核 - [[X] r- [DENDRON] m] n（I）[DENDRON1] p- [X] - [DENDRON] q（II）其中CORE，X，DENDRON，DENDRON1，m，n，p，q和r如本文所定义。 化合物的光学（例如发光）和电子性能能够通过暴露于许多不同的物质而被改变。 本发明还提供上文所公开的化合物在物质特别是炸药的检测中的用途。

公开(公告)号：US07799917B2

公开(公告)日：2010-09-21

申请号：US10525687

申请日：2003-08-28

申请人： Ifor David William Samuel ,  Paul Leslie Burn ,  Shih-Chun Lo

发明人： Ifor David William Samuel ,  Paul Leslie Burn ,  Shih-Chun Lo

IPC分类号： C07F15/00 ,  C09K11/06

CPC分类号： C07F15/0033 ,  C09K2211/1007 ,  C09K2211/185 ,  H01L51/0037 ,  H01L51/0085 ,  H01L51/5016 ,  Y02E10/549 ,  Y10S428/917

摘要： A charge-neutral organometallic dendrimer is described, said dendrimer having the formula (I): CORE-[DENDRITE(-Q)a]n  (I) in which CORE represents a group of formula MXxYz, in which M represents a metal cation, x represents an integer of 1 or more, each X which may be the same or different represents a mono-, bi- or tri-dentate coordinating group, z represents 0 or an integer of 1 or more, and each Y which may be the same or different represents a coordinating group, the total of (b.x)+(c.z) being equal to the number of coordination sites on M, wherein b is the number of coordination sites on X and c is the number of coordination sites on Y; n represents an integer of 2 or more; each DENDRITE which may be the same or different represents a dendritic molecular structure bonded to a group X; a represents 0 or an integer of 1 or more; and each Q which may be the same or different represents a surface group; CORE terminating in the first single bond which is connected to a branching group or branching atom of DENDRITE; which dendrimer has a structure in which no hemisphere of a notional sphere centred on M and containing the dendrimer is devoid of a said first single bond.

摘要翻译： 描述了电荷中性有机金属树枝状聚合物，所述树枝状聚合物具有式（I）：CORE- [DENDRITE（-Q）a] n（I），其中CORE表示式MXxYz的基团，其中M表示金属阳离子， x表示1或更大的整数，每个X可以相同或不同，表示单，双或三齿配位基，z表示0或1或更大的整数，每个Y可以是 相同或不同的表示协调组，（bx）+（cz）的总和等于M上的协调位置数，其中b是X上的协调位点数，c是Y上的协调位点数; n表示2以上的整数， 每个DENDRITE可以相同或不同，表示与基团X键合的树枝状分子结构; a表示0或1或更大的整数; 并且每个可以相同或不同的Q表示表面基团; CORE终止于连接到DENDRITE的支化基团或支化原子的第一单键; 该树枝状聚合物具有这样的结构，其中以M为中心并且含有树枝状大分子的名义球的半球没有所述第一单键。

公开(公告)号：US07626756B2

公开(公告)日：2009-12-01

申请号：US12096524

申请日：2007-01-26

申请人： Malcolm Dunn ,  Cameron F. Rae ,  Tom J. Edwards ,  David J. M. Stothard ,  David Walsh

发明人： Malcolm Dunn ,  Cameron F. Rae ,  Tom J. Edwards ,  David J. M. Stothard ,  David Walsh

IPC分类号： G02F1/35 ,  G02F2/02 ,  G02B6/00

CPC分类号： G02F1/39 ,  G02F1/3501 ,  G02F2203/13

摘要： A coating between a nonlinear crystal and a silicon prism coupler, prevents transmission of radiation scattered within the crystal by filtering out frequencies outside the silicon bandgap to avoid free carrier absorption, but transmits THz frequencies that correspond to the bandgap.

摘要翻译： 非线性晶体和硅棱镜耦合器之间的涂层通过滤除硅带隙外的频率来防止透射散射在晶体内的辐射，以避免自由载流子吸收，而是传输与带隙相对应的THz频率。

公开(公告)号：US07504172B2

公开(公告)日：2009-03-17

申请号：US10523093

申请日：2003-07-31

申请人： John Thomas Sirr Irvine ,  Shanwen Tao

发明人： John Thomas Sirr Irvine ,  Shanwen Tao

IPC分类号： H01M8/12 ,  H01M8/10

CPC分类号： C04B35/42 ,  B01D53/228 ,  C04B35/016 ,  C04B2235/3208 ,  C04B2235/3213 ,  C04B2235/3215 ,  C04B2235/3224 ,  C04B2235/3225 ,  C04B2235/3227 ,  C04B2235/3241 ,  C04B2235/3262 ,  C04B2235/3265 ,  C04B2235/3267 ,  C04B2235/76 ,  C04B2235/761 ,  C04B2235/768 ,  H01M4/8885 ,  H01M4/9033 ,  H01M8/1246 ,  H01M2004/8684 ,  H01M2008/1293 ,  Y02E60/525 ,  Y02P70/56

摘要： The present invention provides a material suitable for use in a solid oxide fuel cell, wherein the material is of an, optionally doped, double perovskite oxide material having the general formula (I): (LnaXb)e(Z1cZ2d)fOg (I) wherein Ln is selected from Y, La and a Lanthanide series element, or a combination of these and X also represents an element occupying the A site of a perovskite oxide and is selected from Sr, Ca and Ba, and Z1 and Z2 represent different elements occupying the B site of a perovskite oxide and are selected from Cr, Mn, Mg and Fe, and wherein a has a value from 0 to 1, preferably 0.7 to 1.0, b has a value of from 1 to 0, preferably 0.3 to 0, and each of c and d has a value of from 0.25 to 0.75, provided that a+b has a value of 1, and c+d, has a value of 1, and wherein e has a value of from 0.8 to 1, wherein f has a value of from 0.8 to 1, and g has a value of from 2.5 to 3.2. Also provided are SOFCs having an electrode or functional layer of a material or containing a material of the invention, as well as mixed ionic/electronic conducting membranes suitable for use in a syngas reactor or oxygen separator, comprising a layer of a double perovskite material of the invention, and a method of oxidising a fuel in an SOFC having an anode of a double perovskite material of the invention.

摘要翻译： 本发明提供了一种适用于固体氧化物燃料电池的材料，其中该材料是具有通式（I）的任选掺杂的双钙钛矿氧化物材料：（LnaXb）e（Z1cZ2d）f0g（I）其中 Ln选自Y，La和镧系元素，或者这些和X的组合也表示占据钙钛矿氧化物的A位点的元素，并且选自Sr，Ca和Ba，Z1和Z2代表占据的不同元素 钙钛矿氧化物的B位，选自Cr，Mn，Mg和Fe，并且其中a具有0至1，优选0.7至1.0的值，b具有1至0，优选0.3至0的值， 并且c和d中的每一个具有0.25至0.75的值，条件是a + b的值为1，c + d的值为1，其中e的值为0.8至1，其中 f的值为0.8〜1，g的值为2.5〜3.2。 还提供了具有材料的电极或功能层或含有本发明的材料的SOFC，以及适用于合成气反应器或氧分离器的混合的离子/电子导电膜，包括一层双钙钛矿材料 本发明，以及一种氧化具有本发明的双钙钛矿材料的阳极的SOFC中的燃料的方法。

公开(公告)号：US07294486B2

公开(公告)日：2007-11-13

申请号：US10489032

申请日：2002-09-05

申请人： David O'Hagan ,  Christoph Schaffrath

发明人： David O'Hagan ,  Christoph Schaffrath

IPC分类号： C12P19/38 ,  C12N1/20 ,  A01N43/04 ,  C07H19/00 ,  C07H19/173

CPC分类号： A61K51/0491 ,  C12N9/00 ,  C12P19/40 ,  Y10S435/886

摘要： There is described a process for the synthesis of a fluoronucleoside compound, said process comprising mixing a substrate and an enzyme from Streptomyces cattelya as catalyst. The process may be used to produce an 18F labelled fluoronucleoside compound. There is also described an enzyme derived from Streptomyces cattelya which has the capacity to catalyse the synthesis of a fluoronucleoside compound.

摘要翻译： 描述了合成氟核苷化合物的方法，所述方法包括将底物和酶从链霉菌（Streptomyces cattelya）作为催化剂混合。 该方法可用于产生标记的氟代核苷化合物。 还描述了具有催化氟核苷化合物合成能力的链霉菌（Streptomyces cattelya）的酶。

公开(公告)号：US07148022B2

公开(公告)日：2006-12-12

申请号：US10450342

申请日：2001-12-12

申请人： Michael Ryan ,  Tom Wileman ,  Caroline Knox

发明人： Michael Ryan ,  Tom Wileman ,  Caroline Knox

IPC分类号： C12Q1/00 ,  C12Q1/70 ,  G01N33/53 ,  C07K4/00 ,  C07K14/00

CPC分类号： G01N33/502 ,  A61K38/00 ,  C07K14/005 ,  C12N2770/32022 ,  G01N33/5008 ,  G01N33/56983 ,  G01N2333/085 ,  Y02A50/463 ,  Y02A50/465 ,  Y02A50/54

摘要： There is provided an assay for selecting an anti-viral agent effective against picornavirus infection. The assay selects an agent which disrupts the association between picornavirus protein 2C and the host cell protein D-AKAP2, which association has been found to be essential for successful viral replication. Also disclosed are anti-viral agents having such properties and a method of combating picornavirus replication.

摘要翻译： 提供了选择对小RNA病毒感染有效的抗病毒剂的测定法。 该试验选择破坏小核糖核酸病毒蛋白2C与宿主细胞蛋白D-AKAP2之间的关联的试剂，已经发现这种结合对于成功的病毒复制是必需的。 还公开了具有这些性质的抗病毒剂和抗小RNA病毒复制的方法。

公开(公告)号：US07126028B1

公开(公告)日：2006-10-24

申请号：US09857465

申请日：1999-12-06

申请人： David O'Hagan

发明人： David O'Hagan

IPC分类号： C07C211/03 ,  C07D263/04 ,  C07D207/08

CPC分类号： C07C211/27 ,  C07B2200/07 ,  C07C209/68 ,  C07C211/29 ,  C07C213/00 ,  C07D263/22

摘要： Process for the preparation of chiral compounds of formula (I) comprising contacting a compound of formula (II) with a source of hydrogen or halide; wherein A is a chiral center; X is selected from oxygen, sulphur and nitrogen; n is selected from 0 and 1 and is equal to the valence of X less 2; B is a fragment CR 3 2; Z is hydrogen or halogen; with the proviso that when X is nitrogen, n is 1, one of R 1 and two of R 2 are hydrogen, BZ is CHPh 2, the other R 1 and R 2 do not form together a five membered heterocyclic (pyrrolidone) ring; novel intermediates, novel compounds, polymers and libraries thereof and the use thereof as fine chemicals, and compositions thereof.

摘要翻译： 制备式（I）的手性化合物的方法，包括使式（II）化合物与氢或卤化物源接触; 其中A是手性中心; X选自氧，硫和氮; n选自0和1，等于X的化合价少2; B是片段CR 3 2; Z是氢或卤素; 条件是当X是氮时，n是1，R 1和R 2之一是氢，BZ是CHPh 2，另一个R 1和R 2不一起形成五元杂环（吡咯烷酮）环; 新型中间体，新型化合物，聚合物及其文库及其作为精细化学品的用途及其组合物。

公开(公告)号：US11840766B2

公开(公告)日：2023-12-12

申请号：US16305915

申请日：2017-06-01

申请人： QUEEN'S UNIVERSITY AT KINGSTON ,  UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS

发明人： Brian E. Mariampillai ,  Abrar R. E. Alrashed ,  Cathleen M. Crudden ,  J. Hugh Horton ,  Christopher J. Baddeley ,  Christian R. Larrea

IPC分类号： C23F1/10

CPC分类号： C23F1/10

摘要： An etchant is described that includes an N-heterocyclic carbene and optionally an appropriate solvent. The etchant was effective at etching a metallic surface having, for example, a metal oxide and/or metal, in both solution phase and vapour-phase. The etchant has been shown to effectively etch oxidized copper and tungsten.

公开(公告)号：US11762180B2

公开(公告)日：2023-09-19

申请号：US16622542

申请日：2018-06-15

申请人： UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS

发明人： Kishan Dholakia

IPC分类号： G02B21/00 ,  G01N21/64

CPC分类号： G02B21/0032 ,  G01N21/6458 ,  G01N21/6486 ,  G02B21/0076 ,  G01N2201/0633 ,  G01N2201/0634 ,  G01N2201/06113 ,  G01N2201/08 ,  G02B2207/114

摘要： A light sheet imaging system, such as a light sheet microscope, comprises an illumination arrangement for generating a light sheet for three-photon excitation of a fluorescent sample, and a fluorescence collection arrangement for collecting fluorescence generated in the sample as a result of three-photon excitation by the light sheet. The light sheet may be a non-diffractive, propagation-invariant light sheet. The light sheet may be formed from and/or comprise a Bessel beam. A method of light sheet imaging comprises using a light sheet for three-photon excitation of a fluorescent sample, and collecting fluorescence generated in the sample as a result of three-photon excitation of the sample by the light sheet. Such a method may be used for light sheet microscopy.

公开(公告)号：US11609178B2

公开(公告)日：2023-03-21

申请号：US16976333

申请日：2019-02-27

申请人： UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS

发明人： Stephen H. Gillespie ,  Robert J. H. Hammond

IPC分类号： G01N21/03 ,  G01N21/51

摘要： An apparatus for analysing a liquid sample comprising particles, comprises: a first chamber (12) and a second chamber (14), and an optical path between the first chamber (12) and the second chamber (14), wherein: the first chamber (12) is a sample chamber comprising: a sample space for receiving the sample; a light input (24) for input of light into the first chamber (12) for interaction with the sample; and an exit aperture (26) arranged for scattered and/or reflected light to pass from the first chamber via the optical path to the second chamber (14); the second chamber (14) is a detection chamber comprising: an input aperture (28) for receiving light from the optical path; and a detector (25) for detecting, or a detector aperture for receiving, light to be detected; wherein the first chamber (12) and the second chamber (14) provide at least one light integrating volume, and wherein the first chamber (12) is configured such that in operation the liquid sample is present in the first chamber (12) and isolated from the second chamber (14).