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    Betaine Enhancement of Fermentation to make C4 Diacids
    81.
    发明申请
    Betaine Enhancement of Fermentation to make C4 Diacids 审中-公开
    甜菜碱增强发酵以制备C4二酸

    公开(公告)号：US20150147792A1

    公开(公告)日：2015-05-28

    申请号：US14402347

    申请日：2013-06-27

    Applicant: ARCHER DANIELS MIDLAND COMPANY

    Inventor： Jill Morriss

    IPC: C12P7/46 ,  C12N1/20

    CPC classification number: C12P7/46 ,  C07K14/285 ,  C12N1/20

    Abstract: A method of making a C4 diacid from a sugar source by fermentation with a microorganism is described that includes supplementing the fermentation medium with relatively low amounts of betaine. The use of betaine can substantially reduce or even completely eliminate the need for complex nutrient source such as yeast extract, and eliminate a need for vitamins such as biotin, while maintaining a high level of production of the C4 diacid from a simplified sugar based media. The use of betaine improves yield from sugar, final titer, and rate of production per hour. The method is particularly suitable for microorganisms that otherwise display a dependence on yeast extract for high productivity, more particularly for any bacteria, and most particularly for the production of succinic acid from the bacterium Actinobacillus succinogenes. An improved strain of A succinogenes is also described, having a mutation in a betaine transporter that improves C4 diacid production in the presence of betaine.

    Abstract translation: 描述了通过用微生物发酵从糖源制备C4二酸的方法，其包括用相对少量的甜菜碱补充发酵培养基。 甜菜碱的使用可以显着降低甚至完全消除复杂营养来源如酵母提取物的需要，并且消除对维生素如生物素的需要，同时通过简化的糖基培养基保持C4二酸的高水平生产。 甜菜碱的使用提高了糖的产量，最终滴定度和每小时的产量。 该方法特别适用于微生物，否则显示出依赖于酵母提取物的高生产率，更特别是对于任何细菌，尤其是用于从细菌放线杆菌中产生琥珀酸。 还描述了一种改良的琥珀酸原菌株，其在甜菜碱转运蛋白中具有突变，其在甜菜碱的存在下改善了C4二酸的产生。

    PROCESSES FOR MAKING SUGAR AND/OR SUGAR ALCOHOL DEHYDRATION PRODUCTS
    84.
    发明申请
    PROCESSES FOR MAKING SUGAR AND/OR SUGAR ALCOHOL DEHYDRATION PRODUCTS 审中-公开
    制造糖和/或糖酒精脱水产品的方法

    公开(公告)号：US20150005516A1

    公开(公告)日：2015-01-01

    申请号：US14379642

    申请日：2013-03-07

    Applicant: ARCHER DANIELS MIDLAND COMPANY

    Inventor： Thomas P. Binder ,  Alexandra Sanborn

    IPC: C07D307/46

    CPC classification number: C07D307/46 ,  C07D307/48 ,  C07D307/50 ,  C07D493/04 ,  C07H3/02

    Abstract: A process is disclosed for making dehydration products from an aqueous sugars solution including pentoses, hexoses or both, for example, an aqueous high fructose corn syrup solution, or from an aqueous solution of one or more of the alcohols of such pentoses and hexoses, for example, from an aqueous sorbitol solution, by an acid-catalyzed dehydration using substituted sulfonic acids solubilized in the aqueous sugars or sugar alcohols solution.

    Abstract translation: 公开了一种从包含戊糖，己糖或二者的水性糖溶液制备脱水产物的方法，例如水高果糖玉米糖浆溶液，或由一种或多种戊糖和己糖的醇的水溶液，用于 例如，从山梨醇水溶液中，通过使用溶解在水性糖或糖醇溶液中的取代磺酸进行酸催化脱水。

    PROCESS FOR MAKING LEVULINIC ACID
    86.
    发明申请
    PROCESS FOR MAKING LEVULINIC ACID 审中-公开
    制备维生素A的方法

    公开(公告)号：US20140316159A1

    公开(公告)日：2014-10-23

    申请号：US14358373

    申请日：2012-11-28

    Applicant: ARCHER DANIELS MIDLAND COMPANY

    Inventor： Alexandra Sanborn ,  Thomas Binder

    IPC: C07C51/31

    CPC classification number: C07C51/31 ,  C07C51/00 ,  C07C59/185

    Abstract: A process is described wherein a feed of a six-carbon carbohydrate-containing material or of a furanic dehydration product from a six-carbon carbohydrate-containing material or of a combination of these is supplied to a reactor in a controlled manner over time up to a desired combined or total feed level, and the feed is acid-hydrolyzed to produce levulinic acid. In certain embodiments, derivatives of the levulinic acid are prepared.

    Abstract translation: 描述了一种方法，其中将含六碳碳水化合物的材料或来自含六碳碳水化合物的材料的呋喃脱水产物或它们的组合的进料以受控的方式随时间供应到反应器中， 期望的组合或总进料水平，并且进料被酸水解以产生乙酰丙酸。 在某些实施方案中，制备乙酰丙酸的衍生物。

    SYSTEM FOR USING HEAT TO PROCESS AN AGRICULTURAL PRODUCT, A FLUIDIZED BED COMBUSTOR SYSTEM, AND METHODS OF EMPLOYING THE SAME
    89.
    发明申请
    SYSTEM FOR USING HEAT TO PROCESS AN AGRICULTURAL PRODUCT, A FLUIDIZED BED COMBUSTOR SYSTEM, AND METHODS OF EMPLOYING THE SAME 审中-公开
    使用热处理农业产品的系统，流化床式搅拌机系统及其使用方法

    公开(公告)号：US20130305557A1

    公开(公告)日：2013-11-21

    申请号：US13950391

    申请日：2013-07-25

    Applicant: ARCHER DANIELS MIDLAND COMPANY

    Inventor： Glenn D. Kimball

    IPC: F26B23/02 ,  F26B25/14 ,  F23C10/10 ,  F26B3/20 ,  F23C10/00

    CPC classification number: F23C10/002 ,  F23C10/10 ,  F23G5/0273 ,  F23G5/12 ,  F23G5/24 ,  F23G5/30 ,  F23G5/46 ,  F23G7/10 ,  F23G2203/501 ,  F23G2204/10 ,  F23G2206/10 ,  F23G2206/20 ,  F23G2209/281 ,  F23G2209/30 ,  F23G2900/00001 ,  F23G2900/50208 ,  F23G2900/7012 ,  F23J15/027 ,  F26B3/20 ,  F26B23/028 ,  F26B25/14

    Abstract: Systems and related methods of using heat to process an agriculture/product are provided. The system comprises a circulating fluidized bed combustor, a first conduit system, and an indirect heating dryer. The circulating fluidized bed combustor comprises a combustion chamber configured to combust a fuel to generate a mixture comprising hot gases and particulate matter, and a separation chamber configured to separate at least a portion of the particulate matter from the mixture to form a flow of cleaned hot gas. The first conduit system is configured to conduct the cleaned hot gas to a heat exchanger. The indirect heating dryer is in heat conductive contact with the heat exchanger and configured to use the heat from the cleaned hot gas to indirectly dry the agricultural product without contacting the agricultural product with the cleaned hot gas. The system and methods provide hot gas for efficient and low cost energy formed from alternative and lower cost fuels, including biomass sources, and allows for flexibility and efficiency in numerous manufacturing processes.

    Abstract translation: 提供了使用热处理农业/产品的系统和相关方法。 该系统包括循环流化床燃烧器，第一管道系统和间接加热干燥器。 循环流化床燃烧器包括燃烧室，该燃烧室被配置为燃烧燃料以产生包含热气体和颗粒物质的混合物，以及分离室，其被配置为将至少一部分颗粒物质与混合物分离以形成清洁热流 加油站。 第一管道系统构造成将清洁的热气体导入热交换器。 间接加热干燥器与热交换器导热接触，并且被配置为使用来自清洁的热气体的热量间接干燥农产品，而不将农产品与清洁的热气接触。 该系统和方法提供热气，用于从包括生物质源在内的替代和低成本燃料形成的有效且低成本的能量，并且允许在许多制造过程中的灵活性和效率。

    Process for the production of anhydrosugar alcohols
    90.
    发明申请
    Process for the production of anhydrosugar alcohols 有权
    用于生产脱水糖醇的方法

    公开(公告)号：US20040152907A1

    公开(公告)日：2004-08-05

    申请号：US10712399

    申请日：2003-11-14

    Applicant: Archer-Daniels-Midland Company

    Inventor： Kevin M. Moore ,  Alexandra J. Sanborn

    IPC: C07D307/02 ,  C07C033/02 ,  C07C031/18

    CPC classification number: C07H1/00 ,  C07D493/04

    Abstract: A process is provided for the preparation of anhydrosugar alcohols. The process involves heating a sugar alcohol or a monoanhydrosugar alcohol starting material in the presence of an acid catalyst, and subsequent purification of the anhydrosugar alcohol. In some embodiments of the present invention, film evaporators are used in distillation and purification of the anhydrosugar alcohols. Anhydrosugar alcohols of very high purity are achieved in the practice of the present invention. In some embodiments of the present invention, very high purities of the anhydrosugar alcohols are achieved without the use of organic solvents.

    Abstract translation: 提供了用于制备脱水葡萄糖醇的方法。 该方法包括在酸催化剂存在下加热糖醇或单一脱水葡萄糖醇原料，随后纯化脱水葡萄糖醇。 在本发明的一些实施方案中，薄膜蒸发器用于蒸馏和纯化脱水葡萄糖醇。 在本发明的实践中实现了非常高纯度的脱水葡萄糖醇。 在本发明的一些实施方案中，在不使用有机溶剂的情况下实现非常高纯度的脱水糖醇。

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