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公开(公告)号：US5791921A
公开(公告)日：1998-08-11
申请号：US780794
申请日：1997-01-09
Applicant: Anthony Lee
Inventor： Anthony Lee
Abstract: A universal adapter includes: a casing combinable with a front cover and a rear cover having a pair of outlet sockets formed in the rear cover to output power, a first plug having a pair of rectangular-shaped pins slidably held in an upper chamber in the casing and operatively pushed or pulled by a pair of first seesaw buttons pivotally secured on two opposite sides of the first plug for a convenient extending or retraction of the first plug, whereby upon extending of the first plug, a rectangular-shaped pin of "grounding pin" will be simultaneously biased for its forward extending to form triple rectangular-shaped pins for connecting municipal power such as in England or Africa to be output through the pair of outlet sockets in the rear cover; a second plug having a pair of flat blades slidably held in a lower chamber in the casing and operatively pushed or pulled by a pair of second seesaw buttons for a convenient extension or retraction for connecting municipal power to the two outlet sockets; and a third plug having a pair of round pins pivotally mounted on the front cover to be horizontally extended for power connection use and vertically received into the front cover when not in use.
Abstract translation: 通用适配器包括：可与前盖组合的外壳和后盖，其具有形成在后盖中的一对出口插座以输出动力;第一插头，其具有可滑动地保持在上盖中的一对矩形销 壳体并且通过枢转地固定在第一插头的两个相对侧上的一对第一跷跷板按钮可操作地推动或拉动以便于第一插头的方便的延伸或缩回，由此在第一插头延伸时，形成“接地 销“将被同时偏置以使其向前延伸以形成用于连接诸如英国或非洲的市政电力的三角矩形销，以通过后盖中的一对出口插孔输出; 第二插头具有可滑动地保持在壳体中的下腔室中的一对扁平叶片，并由一对第二跷跷板按钮可操作地推动或拉动，用于将市政电力连接到两个出口插座的方便的延伸或缩回; 以及第三插头，其具有枢转地安装在所述前盖上的一对圆形销，以水平延伸用于电力连接使用，并且在不使用时垂直地容纳在所述前盖中。
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公开(公告)号：US5781682A
公开(公告)日：1998-07-14
申请号：US595149
申请日：1996-02-01
Applicant: Mitchell Simmons Cohen , Marco Gauvin , Glen Walden Johnson , Daniel M. Kuchta , Andre Lacerte , Nicholas Anthony Lee , Sylvain Ouimet , Stephen Louis Spanoudis , Stephane Tremblay , Jeannine Madelyn Trewhella
Inventor： Mitchell Simmons Cohen , Marco Gauvin , Glen Walden Johnson , Daniel M. Kuchta , Andre Lacerte , Nicholas Anthony Lee , Sylvain Ouimet , Stephen Louis Spanoudis , Stephane Tremblay , Jeannine Madelyn Trewhella
CPC classification number: G02B6/4292 , G02B6/4249 , G02B6/4255 , G02B6/4261 , G02B6/4272 , G02B6/4274 , G02B6/4277 , G02B6/4284 , H01L27/10852 , H01L28/84 , G02B6/3893 , G02B6/4245 , G02B6/4283 , H01L2924/0002
Abstract: Parallel optical coupling apparatus for coupling a connector attached to one end of a parallel optical cable to a receiver or transmitter array. A parallel fiber optic assembly includes a receiver or transmitter array subassembly that houses a parallel optical coupler for transferring optical signals from an array of sources (e.g., lasers) in the assembly to the connector, or from the connector to an array of receiving elements in the assembly. A connector shell is provided that properly aligns the connector with respect to the optical coupler array.
Abstract translation: 用于将连接到并行光缆的一端的连接器耦合到接收器或发射器阵列的并行光耦合装置。 并联光纤组件包括接收器或发射器阵列子组件，其容纳用于将光信号从组件中的源阵列（例如，激光器）传送到连接器或从连接器到接收元件阵列的并行光耦合器 大会。 提供连接器壳体，其使连接器相对于光耦合器阵列正确对准。
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公开(公告)号：US20250120421A1
公开(公告)日：2025-04-17
申请号：US18380541
申请日：2023-10-16
Applicant: Rachel Tinker-Kulberg , Anthony Lee Dellinger , Terry Earl Brady , Melinda K. M. Goddard , Lance Toland , Christopher L. Kepley
Inventor： Rachel Tinker-Kulberg , Anthony Lee Dellinger , Terry Earl Brady , Melinda K. M. Goddard , Lance Toland , Christopher L. Kepley
IPC: A23K50/80 , A23K10/22 , A23K20/147 , A23K20/174 , A23K20/20
Abstract: The invention presents a novel feed formulation and processing optimized for horseshoe crabs in prolonged captivity, with application to myriad species. The formulation is not only sustainable but environmentally advantageous at scale by utilizing fish and poultry processing by-products. The nutrient-rich waste products are enhanced through cold-processed, enzymatic liquefication and fermentation, which preserves proteins and vitamins and thus, nutrient integrity and bioavailability. The formulation is matched to the composition of the horseshoe crab and the flora and fauna of its habitat diet. Feed efficacy can be measured by observed attraction and palatability, as well as parameters including but not limited to cellular integrity and amebocyte reactivity, weight, disease resistance, and carapace metrics. The feed matrix is designed to stimulate benthic foraging and feeding behaviors of horseshoe crabs but can be matched to alternative species feeding behaviors in aquaculture, agriculture, and other captivity settings, including nourishment of companion animals.
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公开(公告)号：US12225906B1
公开(公告)日：2025-02-18
申请号：US18897019
申请日：2024-09-26
Applicant: Terry Earl Brady , Anthony Lee Dellinger , Lowell Hughes , Melinda K. M. Goddard , Christopher E. Starr , Abed Alqader Ibrahim
Inventor： Terry Earl Brady , Anthony Lee Dellinger , Lowell Hughes , Melinda K. M. Goddard , Christopher E. Starr , Abed Alqader Ibrahim
Abstract: The sustenance of life is driven by recognition of and access to energy sources. This process has remained unchanged over billions of years, guiding cellular nutrition through molecular recognition, akin to the food pyramid. At the atomic or nanoscale, chemotaxis enables organisms to identify ingestible matter and is driven by their need for fuel, rather than from the sustenance itself. Chemotaxis, one of nature's most potent yet invisible organic forces, operates independently of molecular charge dynamics to locate and identify microscopic sustenance. Infectious organisms, such as pathogenic microbes and parasites, depend on chemotactic pathways to locate nutrition across all scales. This invention leverages this phenomenon by “baiting” these pathways with nutritive matter that encapsulates biocidal agents that are harmless to humans but lethal to infectious organisms once ingested. These nutritive biocidal agents could be employed as topical, oral, injectable, or aerosolized formulations, as well as hydrogel or slow-release implants.
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公开(公告)号：US12005077B1
公开(公告)日：2024-06-11
申请号：US18374342
申请日：2023-09-28
Applicant: Terry Earl Brady , Anthony Lee Dellinger , Lowell Hughes , Melinda K. M. Goddard , Christopher E. Starr , Abed Alqader Ibrahim
Inventor： Terry Earl Brady , Anthony Lee Dellinger , Lowell Hughes , Melinda K. M. Goddard , Christopher E. Starr , Abed Alqader Ibrahim
Abstract: The present invention introduces an ophthalmic solution containing halo-fullerenes. When the spherical fullerene carbon cages are functionalized with halogens, the resulting halo-fullerenes demonstrate sustained antimicrobial activity. Fullerenes are also characterized by unique electron properties that impart antioxidant capabilities as free radical scavengers. Nonetheless, far smaller than ocular tissue cells, halo-fullerenes are biocompatible—and capable of penetrating intricate barriers, like the cornea and conjunctiva, with potential to achieve greater efficacy and symptom relief in chronic dry eye than conventional treatments. With remarkable surface area, halo-fullerenes also allow customization and possess a unique molecular architecture for broader applications. This multifunctional solution thus imparts antimicrobial activity, antioxidative protection, molecular lubrication, and shielding from external irritants while penetrating dense ocular structures. Without the need for antibiotic additives or preservatives, the invention can offer an effective, safe option for dry eye treatment, prophylaxis in contact lens solutions, and post-surgical care.
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Patent Agency Ranking
公开(公告)号：US11872109B1
公开(公告)日：2024-01-16
申请号：US18237019
申请日：2023-08-23
Applicant: Lowell Hughes , Anthony Lee Delligner , Melinda K. M. Goddard , Terry E. Brady
Inventor： Lowell Hughes , Anthony Lee Delligner , Melinda K. M. Goddard , Terry E. Brady
Abstract: The present innovation is a customized compression device for prevention and treatment of keloids and hypertrophic scarring, primarily a frequent complication of ear piercing. The “one size fits all” design of traditional devices can compromise efficacy due to uneven fit and compression. This invention harnesses 3D digital scanning to capture the intricate contours of the ear for every patient, for personalized compression therapy. Using 3D printing, shells are fabricated with biocompatible materials such as Polylactic Acid, shape memory polymers, or silicone-based substances. In primary embodiments, device functionality is achieved with compression clips or spring-open, single-piece structures. The custom fit, potential for infusion of therapeutic agents (e.g., corticosteroids), and engineered porosity combine to improve keloid management from uniform pressure distribution and optimal healing. Additionally, the ‘shells’ can be pigmented to match patient skin tones and encourage compliance. The invention thus offers tailored keloid treatment, as well as prevention for high-risk individuals.
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公开(公告)号：US11813363B1
公开(公告)日：2023-11-14
申请号：US18118919
申请日：2023-03-08
Applicant: Terry Earl Brady , Anthony Lee Dellinger , Melinda K. M. Goddard , Lowell Hughes , Dick Luttekes
Inventor： Terry Earl Brady , Anthony Lee Dellinger , Melinda K. M. Goddard , Lowell Hughes , Dick Luttekes
CPC classification number: A61K9/4833 , A23L33/40 , A61K9/4825 , A61K47/14
Abstract: The gut-brain axis, neurobiology and neurotransmission are physiologic systems with known pathways, yet they are rarely leveraged for wellness, notwithstanding extensive literature regarding healthy diets and nutrition. Gastrointestinal (GI) evolution has equipped humans with exceptional plasticity for food abundance or scarcity, while maintaining homeostasis by producing essential neurotransmitters that drive fundamental behaviors, from seeking nourishment to engaging in routine tasks of life. The advent of cheap, abundant, and highly processed foods in the last century, however, has upended the very systems that evolved for survival with a debilitating propensity for obesity in abundance—and malnourishment where access may be limited to a scarce supply of such processed foods, or none at all. In short, a better understanding and application of physiologic signaling and equilibrium is needed in cases of weight management and malnourishment. Neurotransmitters, especially serotonin, are the primary moieties that have beneficial capacity in routine tasks, consuming but not overconsumption of needed sustenance, and achieving wellness overall. Thus, this invention provides a novel delivery mechanism of micro-dosed, natural ingredients for stimulating production of a calibrated serotonin level by leveraging the gut-brain axis through organic nutrient conversion without synthetic pharmacologic compounds. Herein, specifically engineered foodstuff that converts to serotonin (or other mediators of neurobiology) is designed to facilitate weight management and may be applied to mitigate risks of malnourishment maladies such as childhood stunting by employing directed neurobiology.
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公开(公告)号：US11638720B1
公开(公告)日：2023-05-02
申请号：US17973753
申请日：2022-10-26
Applicant: Terry Earl Brady , Anthony Lee Dellinger , Lowell Hughes , Melinda K. M. Goddard , Julie Catherine-Elise Hakim
Inventor： Terry Earl Brady , Anthony Lee Dellinger , Lowell Hughes , Melinda K. M. Goddard , Julie Catherine-Elise Hakim
IPC: A61K33/18 , A61K9/00 , A61K31/19 , A61K33/00 , A61K33/16 , A61K33/20 , A61K36/00 , A61K36/14 , A61K36/23 , A61K36/28 , A61K36/288 , A61K36/30 , A61K36/45 , A61K36/734 , A61K36/75 , A61K33/14
Abstract: The present invention pertains to quantum-scale biocidal particles and chemical reactions that disrupt and eviscerate microbial matter by combining aqueous and dry components. As halo-fullerene activation requires volatile excitation to mix, contact and collide so as to rupture microbial matter, atomic scale chemical reactions impart the requisite movement of engineered halo-fullerenes to destroy bacterial, fungal and viral matter upon contact.
The present invention includes two primary mechanisms: an excitation chemistry and biocidal, hydrophobic halo-fullerenes. Upon aqueous exposure, the dry composition initiates a chemical reaction that activates biocidal halo-fullerenes to disrupt biologic surfaces in topical applications. The object of the present invention is a shelf stable, pre-packaged wiping material or dry packet for rehydration with broad spectrum antimicrobial activity. In one example, a matrix or wipe material would be comprised of densely packed and highly concentrated halo-fullerenes and a chemical reaction stimulant. When activated upon aqueous exposure, it would relax water molecules, alter hydrogen binding, and disrupt adhesion and cohesion forces that characterize surface tensions. These dynamics would then isolate sebaceous substances and free oxygen radicals, along with outgassing of carbon dioxide. The chemical reaction stimulant thus transfers energy and hyperactivates otherwise inert halo-fullerenes to form a biocidal composition.
Broader utilities range from topical cleansing for personal hygiene, as well as various clinical and surgical procedures, as surgical and prophylactic lavage and rinse solutions, and enteral formulations as a hypertonic renal flush combined with short-acting diuresis. The halo-fullerene and hypertonic renal flush would cause osmotic cellular outflow, mitigate cellular microbial uptake and initial seroconversion and bloodborne events, while a botanical diuretic agent would facilitate systemic prophylaxis or treatment of UTIs.-
公开(公告)号：US20220323498A1
公开(公告)日：2022-10-13
申请号：US17641473
申请日：2020-09-10
Applicant: Dean Anthony LEE , Jena Edwards MOSEMAN , RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL
Inventor： Dean Anthony LEE , Jena Edwards MOSEMAN
Abstract: Disclosed are compositions and methods for measuring the likelihood of recovery of a recently thawed immune cell. Methods include assaying the level of an ADAM-17-cleaved surface receptor expressed on the immune cells, wherein the level of the surface receptor directly correlates with the likelihood of immune cell recovery (i.e., the greater the increase of the expression level an ADAM-17-cleaved surface receptor relative to a control, the greater the likelihood of recovery). The method can be used to determine if immune cells have sufficient viability to be used in immunotherapy before use.
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公开(公告)号：US11298375B2
公开(公告)日：2022-04-12
申请号：US17499223
申请日：2021-10-12
Applicant: Terry Earl Brady , Anthony Lee Dellinger , Melinda K. M. Goddard , Kristen Dellinger
Inventor： Terry Earl Brady , Anthony Lee Dellinger , Melinda K. M. Goddard , Kristen Dellinger
Abstract: The present invention provides the methods and composition useful as a contraceptive by preventing motile sperm from reaching a mature ovum, thereby blocking fertilization and preventing pregnancy. The contraceptive is comprised of halogen functionalized fullerene nanoparticles (halo fullerenes) and chemotactic stimulants that act synergistically to divert, incapacitate and ultimately rupture spermatozoa to avert fertilization. When applied vaginally prior to coitus, the suspension is activated by exposure to spermatozoa upon insemination. Notably, non-spermatozoa cells are unaffected by the pH-neutral suspension; however, closer to the same scale, microbes are susceptible to its inherent biocidal properties. Following application and coitus, the contraceptive evacuates naturally, along with seminal and vaginal fluids thereafter.
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