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公开(公告)号：US20220340494A1
公开(公告)日：2022-10-27
申请号：US17642326
申请日：2020-09-10
Applicant: Kansas State University Research Foundation
Inventor： Gurpreet Singh , Zhongkan Ren
Abstract: Ceramic matrix composite (CMC) materials are a desired solution for lightweight and high temperature applications. CMC materials can be reinforced with polymer-derived ceramic (PDC) fibers, which advantageously possess intrinsic thermal stability and high mechanical strength. Carbon-rich SiOC and SiOCN fibers were synthesized via hand-drawing and electrospinning polymer pyrolysis of a hybrid precursor materials with the aid of a spinning reagent. The prepared fibers are crosslinked and pyrolyzed for polymer-to-ceramic conversion.
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公开(公告)号：US20220338471A1
公开(公告)日：2022-10-27
申请号：US17762994
申请日：2020-09-23
Applicant: Kansas State University Research Foundation , The United States of America, as represented by the Secretary of Agriculture , Board of Regents of The University of Nebraska
Inventor： Yoonseong Park , Ronald Nachman , Troy Anderson
Abstract: Described herein are bee-safe acaricides that target the varroa mite-specific neuropeptidergic system regulated by proctolin, and methods of use. The acaricides comprise a peptide analog or peptidomimetic of varroa mite proctolin for selective targeting of this pest in a bee colony. The compounds are also effective against other pests, such as ticks. The peptide analog or peptidomimetic generally comprises one or two amino acid residue substitutions or insertions. Also described herein are methods of screening compounds for activity on a proctolin receptor.
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公开(公告)号：US11445674B2
公开(公告)日：2022-09-20
申请号：US17037828
申请日：2020-09-30
Inventor： Jesse Poland , Bernd Friebe , Titiana Danilova , Bikram S Gill , Eric Jackson
Abstract: The present disclosure relates to wheat plants having grain with high β-glucan content, methods for constructing said wheat plants, grain therefrom and uses thereof. Wheat lines homozygous for the HvCslF6 gene from barley having five times the fiber content and an increased β-glucan content of TA5790, TA5792, and TA5795 are disclosed.
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公开(公告)号：US20220279704A1
公开(公告)日：2022-09-08
申请号：US17630206
申请日：2020-07-24
Applicant: Kansas State University Research Foundation
Inventor： Ajay Sharda , Sylvester Badua , Daniel Flippo
IPC: A01C7/10 , A01C5/06 , G05B19/4155
Abstract: A system for measuring real-time seed placement of seeds, such as corn seeds, during planting is provided. In certain embodiments, the sensing and measurement (SAM) system comprises various elements selected from the group consisting of a high-speed camera, light-section sensor, potentiometer, GPS unit, data acquisition system, and a control computer. The SAM system measures seeding depth, seed spacing, and geo-location of the seed. It is mounted on a planter row unit located in between the closing wheels and the gauge wheels with the camera and light section sensor directly facing the furrow.
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公开(公告)号：US20220204447A1
公开(公告)日：2022-06-30
申请号：US17428070
申请日：2020-02-04
Applicant: Kansas State University Research Foundation
Inventor： Duy H. Hua
IPC: C07D205/08 , C07D207/28 , C07D211/78 , C07D305/12 , C07D307/33 , C07D309/30 , C07D487/04 , C07D471/22 , C07J1/00 , C07D471/04 , C08F226/10 , C08F126/10 , B01J35/02
Abstract: Chiral polyvinylpyrrolidinone (CSPVP), complexes of CSPVP with a core species, such as a bimetallic nanocluster catalyst, and enantioselective oxidation reactions utilizing such complexes are disclosed. The catalytic complexes have exhibited the ability to achieve reaction products have a very high degree of optical purifies. These reaction products can be used as reagents in the synthesis of complex organic molecules, such as bioactive products, and C—H bond oxidation of complex molecules including various drugs and natural products.
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Patent Agency Ranking
公开(公告)号：US20220183277A1
公开(公告)日：2022-06-16
申请号：US17441916
申请日：2020-03-20
Applicant: Kansas State University Research Foundation
Inventor： John M. Tomich , Sheila de Mello Barros , Susan K. Whitaker , Pinakin Sukthankar
Abstract: Described herein are linear peptides for creation of colloidal particles and micelles for delivery of active agents. The colloidal particles facilitate encapsulation and delivery of hydrophobic and/or poorly water soluble active agents within the particle hydrophobic core. The compositions are suitable for delivery of active agents to plants and animals.
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87.发明申请公开(公告)号：US20220175661A1
公开(公告)日：2022-06-09
申请号：US17442349
申请日：2020-03-25
Applicant: Kansas State University Research Foundation
Inventor： Viktor Chikan , Ryan Rafferty
Abstract: Methods for enhancing intracellular uptake of active agents by inducing temporary pore formation in a cell membrane are described. The methods generally comprise introducing nanoparticles to a cell in vivo, ex vivo, or in cell culture to magnetic nanoparticles that are taken up into the cell interior. The methods further comprise introducing active agents to the cell. A magnetic field is applied to the cell for targeted excitation of the internalized magnetic nanoparticles to induce temporary pore formation in the cell membrane, such that the active agent is taken up in an increased amount and/or at an increased rate by the cell.
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公开(公告)号：US11279945B2
公开(公告)日：2022-03-22
申请号：US16098680
申请日：2017-05-04
Inventor： Dorith Rotenberg , Anna E. Whitfield , William W. Bockus , Forrest G. Chumley , Rodolfo Acosta-Leal
IPC: C12N15/82
Abstract: Isolated cDNA sequences encoding for highly conserved domains of plant viral pathogen genomes. The cDNA sequences are selected from the group consisting of those listed in Table I (SEQ ID NOs: 1-68). cDNA fusion constructs or chimeric transgene constructs comprising at least two different cDNA sequences selected from the list in Table I, and more specifically cDNA corresponding to at least two different viruses is described, along with methods of creating transgenic plants with broad-spectrum, durable resistance to multiple viral pathogens using these cDNA sequences.
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公开(公告)号：US11254048B2
公开(公告)日：2022-02-22
申请号：US16487622
申请日：2018-02-20
Applicant: Kansas State University Research Foundation
Inventor： Dong Lin , Pedram Parandoush
IPC: B29C64/147 , B29C64/268 , B29C64/218 , B29C65/08 , B29C70/38 , B29C70/54 , B29C65/00 , B29C65/16 , B29C65/74 , B33Y80/00 , B33Y10/00
Abstract: Additive manufacturing systems and methods used for creating 3D parts from continuous-fiber reinforced composites such as, e.g., carbon-fiber or glass-fiber pre-impregnated tape are provided. The systems and methods lay tape in successive layers and cut each layer according to a 2D slice of a 3D CAD file. During the placement of each piece of tape, a laser welds the tape to other tape, eliminating the need for post-processing of each layer. By utilizing tape instead of large fiber-reinforced sheets, the systems and methods described herein reduce waste compared to known manufacturing techniques.
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公开(公告)号：US20220031869A1
公开(公告)日：2022-02-03
申请号：US17296379
申请日：2019-11-26
Applicant: Kansas State University Research Foundation
Inventor： Santosh Aryal , Arunkumar Pitchaimani , Tuyen DT Nguyen
IPC: A61K49/18 , A61K9/127 , A61K47/69 , A61P35/00 , A61K31/704
Abstract: Synthetic nanocarrier constructs and related compositions comprising a lipid-based bilayer membrane infused with one or more NK-92 cell membrane proteins, which encapsulates a liquid receiving interior space or coats at least a portion of a solid core. Methods of targeted delivery of an active/diagnostic/imaging agent to a specific cell type or a region of a patient by administering a plurality of nanocarrier constructs to the patient. MRI imaging methods and novel MRI contrast agent constructs are also disclosed.
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