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公开(公告)号：US20100168541A1
公开(公告)日：2010-07-01
申请号：US12636540
申请日：2009-12-11
IPC分类号： A61B5/1495 , A61B5/145
CPC分类号： A61B5/1495 , A61B5/14532 , A61B2560/0223 , G06F19/00
摘要： Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
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公开(公告)号：US07715893B2
公开(公告)日：2010-05-11
申请号：US11004561
申请日：2004-12-03
IPC分类号： A61B5/00
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/1495 , A61B5/7203 , A61B5/742 , A61B2560/0223 , B33Y70/00 , B33Y80/00
摘要： Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.
摘要翻译： 本文公开了用于校准连续分析物传感器（例如连续葡萄糖传感器）的系统和方法。 一个这样的系统利用一个或多个电极来测量另外的分析物。 这样的测量可以提供用于校准传感器的基线或灵敏度测量。 此外，可以使用基线和/或灵敏度测量来触发诸如数字数字滤波或暂停显示数据的事件。
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公开(公告)号：US20100063373A1
公开(公告)日：2010-03-11
申请号：US12619502
申请日：2009-11-16
IPC分类号： A61B5/1468
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/1495 , A61B5/7203 , A61B5/742 , A61B2560/0223 , B33Y70/00 , B33Y80/00
摘要： Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.
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公开(公告)号：US09155843B2
公开(公告)日：2015-10-13
申请号：US13559454
申请日：2012-07-26
申请人： James H. Brauker , Mark A. Tapsak , Sean T. Saint , Apurv Ullas Kamath , Paul V. Neale , Peter C. Simpson , Michael Robert Mensinger , Dubravka Markovic
发明人： James H. Brauker , Mark A. Tapsak , Sean T. Saint , Apurv Ullas Kamath , Paul V. Neale , Peter C. Simpson , Michael Robert Mensinger , Dubravka Markovic
IPC分类号： A61M31/00 , A61M1/00 , A61M5/315 , A61B5/00 , A61B5/145 , G06F19/00 , A61M5/172 , A61B5/1486
CPC分类号： A61M5/31525 , A61B5/0002 , A61B5/14532 , A61B5/1486 , A61B5/14865 , A61B5/4839 , A61B2560/0443 , A61M5/1723 , A61M11/00 , A61M15/0001 , A61M2005/1726 , A61M2205/18 , A61M2205/3303 , A61M2205/502 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3468 , G16H20/17 , G16H40/63
摘要： Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.
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公开(公告)号：US09107623B2
公开(公告)日：2015-08-18
申请号：US12424391
申请日：2009-04-15
申请人： James H. Brauker , Victoria E. Carr-Brendel , Paul V. Goode , Apurv Ullas Kamath , James Patrick Thrower , Ben Xavier
发明人： James H. Brauker , Victoria E. Carr-Brendel , Paul V. Goode , Apurv Ullas Kamath , James Patrick Thrower , Ben Xavier
IPC分类号： A61B5/05 , A61B5/145 , A61B5/1468 , A61B5/1486 , A61B5/1495 , A61B5/00
CPC分类号： A61B5/14532 , A61B5/145 , A61B5/14503 , A61B5/1451 , A61B5/1468 , A61B5/1473 , A61B5/1486 , A61B5/14865 , A61B5/1495 , A61B5/7257 , A61B5/726 , A61B5/7264 , A61B5/7275 , A61B5/742 , A61B5/7455 , A61B5/746 , A61B5/7475 , A61M5/1723 , G06F19/00 , Y02A90/22 , Y02A90/26
摘要： Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.
摘要翻译： 用于动态和智能地估计来自连续分析物传感器的分析物数据的系统和方法，包括接收数据流，选择多种算法中的一种，以及采用所选择的算法来估计分析物值。 附加数据处理包括评估所选择的估计算法，基于统计学，临床或生理参数分析估计分析物值的变化，将估计的分析物值与相应的测量分析物值进行比较，以及向用户提供输出。 估计可用于补偿时间滞后，匹配传感器数据与相应的参考数据，警告即将到来的临床风险，替换错误的传感器数据信号，并提供更及时的分析物信息，鼓励主动行为和抢占临床风险。
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公开(公告)号：US08700117B2
公开(公告)日：2014-04-15
申请号：US12633654
申请日：2009-12-08
IPC分类号： A61B5/05
CPC分类号： A61B5/1468 , A61B5/0031 , A61B5/1433 , A61B5/14532 , A61B5/14546 , A61B5/1473 , A61B5/14865 , A61B5/1495 , A61B5/150022 , A61B5/4839 , A61B5/743 , A61B2560/0223 , A61B2560/04 , A61B2562/085 , G01N33/48707 , G06F19/00 , Y02A90/22 , Y02A90/26
摘要： Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
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公开(公告)号：US08611978B2
公开(公告)日：2013-12-17
申请号：US12683755
申请日：2010-01-07
CPC分类号： A61B5/1495 , A61B5/0031 , A61B5/14503 , A61B5/1451 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/14735 , A61B5/1486 , A61B5/14865 , A61B2560/0223
摘要： Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
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公开(公告)号：US08588882B2
公开(公告)日：2013-11-19
申请号：US12639746
申请日：2009-12-16
IPC分类号： A61B5/05
CPC分类号： A61B5/1468 , A61B5/0031 , A61B5/1433 , A61B5/14532 , A61B5/14546 , A61B5/1473 , A61B5/14865 , A61B5/1495 , A61B5/150022 , A61B5/4839 , A61B5/743 , A61B2560/0223 , A61B2560/04 , A61B2562/085 , G01N33/48707 , G06F19/00 , Y02A90/22 , Y02A90/26
摘要： Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
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公开(公告)号：US08548553B2
公开(公告)日：2013-10-01
申请号：US13531360
申请日：2012-06-22
IPC分类号： A61B5/05
CPC分类号： A61B5/14532 , A61B5/0015 , A61B5/14865 , A61B5/1495 , A61B5/7275 , A61B5/742 , G16H40/40 , Y02A90/26
摘要： Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
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公开(公告)号：US08386004B2
公开(公告)日：2013-02-26
申请号：US13227290
申请日：2011-09-07
IPC分类号： A61B5/05
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/1495 , A61B5/7203 , A61B5/742 , A61B2560/0223 , B33Y70/00 , B33Y80/00
摘要： Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.
摘要翻译： 本文公开了用于校准连续分析物传感器（例如连续葡萄糖传感器）的系统和方法。 一个这样的系统利用一个或多个电极来测量另外的分析物。 这样的测量可以提供用于校准传感器的基线或灵敏度测量。 此外，可以使用基线和/或灵敏度测量来触发诸如数字数字滤波或暂停显示数据的事件。
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