摘要:
A method for treating the lung during an acute episode of reversible chronic obstructive pulmonary disease such as an asthma attack. The method comprises transferring energy to an airway wall of an airway such that a diameter of the airway is increased. The energy may be transferred to the airway wall prior to, during or after an asthma attack. The energy may be transferred in an amount sufficient to temporarily or permanently increase the diameter of the airway. The method may be performed while the airway is open, closed or partially closed.
摘要:
Described herein are adhesive nasal devices. In particular, the adhesive nasal respiratory devices described herein are configured to be worn in communication with a subject's nasal cavity and may include a rim body having a passageway therethrough, an airflow resistor in communication with the passageway of the rim body, and a flexible, adhesive holdfast layer extending outward from the periphery of the rim body. The rim body region may be formed from multiple parts (e.g., a first and a second rim body region), and the airflow resistor may be secured between the parts forming the rim body. Methods of manufacturing and assembling these adhesive nasal devices are also described.
摘要:
Whole-nose nasal respiratory devices and methods of making and using whole-nose nasal respiratory devices are described and illustrated herein. These devices are typically configured to be adhesively secured to a subject so that they engage both of the subject's nostrils and allow airflow from both nostrils to communicate with an airflow resistor. The airflow resistor is configured so that it inhibits exhalation through the nostrils more than it inhibits inhalation through the nostrils.
摘要:
Described herein are adjustable whole-nose nasal devices having a first passageway for communication with a first nasal passage and a second passageway for communication with a second nasal passage, an airflow resistor that inhibits expiration more than inspiration, and an adjustable connector. The adjustable connector may include one or more adjustable joints or regions that allow the whole-nose device to conform to the spacing between a subject's nostrils, and/or the orientation and angle of the subject's nostrils. Also described herein are whole-nose devices having a single airflow resistor communicating with both of a subject's nasal passages. Methods of treating a disorder using the whole-nose nasal devices are also described.
摘要:
Described herein are applicator systems and applicators for nasal devices, and methods of applying nasal devices. In general, an applicator system includes a nasal device and one or more of: an inserter from which the nasal device is released, a handle that is releasably connected to the nasal device, or an applicator liner that can be removed after positioning the device relative to the nasal cavity.
摘要:
Described herein are nasal respiratory devices, in particular, nasal respiratory devices configured to achieve positive end-expiratory pressure (PEEP) in a subject wearing the device. PEEP devices may have a threshold pressure for opening during expiration. In some variations, these devices have a threshold pressure for closing during expiration.
摘要:
Described herein are nasal respiratory devices and methods for treating a variety of medical diseases including snoring and sleep apnea through the use of such devices. In general, these devices include an airflow resistor, such as a flap valve and a holdfast for securing the device in communication with the subject's nasal cavity. The devices may be configured to include leak paths to regulate the expiratory pressure when worn by a subject. Methods for using these devices may include securing a device over or at least partially within (or both of) a subject's nasal cavities.
摘要:
Devices and methods for altering gaseous flow within a lung to improve the expiration cycle of an individual, particularly individuals having chronic obstructive pulmonary disease. The methods and devices create channels in lung tissue and maintain the patency of these surgically created channels in tissue. Maintaining the patency of the channels allows air to pass directly out of the lung tissue which facilitates the exchange of oxygen ultimately into the blood and/or decompresses hyper-inflated lungs.
摘要:
The intrastromal corneal ring is adjustable in thickness and has an elongated, flexible, preferably transparent or translucent body which forms a circle. The intrastromal corneal ring is of a size such that it can be inserted into a human eye and is comprised of a material which is compatible with human ocular tissue. The thickness of the ring can be adjusted so that it is not necessary to stock a plurality of different rings of different sizes to be used in connection with a method of adjusting the shape of the cornea of the eye. A plurality of different embodiments of intrastromal corneal rings are disclosed each of which are adjustable in terms of their thickness. The thickness may be adjusted prior to the insertion of the intrastromal corneal ring into the cornea and may not be further adjustable after insertion. However, in accordance with preferred embodiments the intrastromal corneal ring is inserted at a thickness which is believed to be proper and may thereafter be further adjusted in order to precisely define the desired thickness and thereby more precisely adjust the shape of the cornea and focus the light entering the eye on the retina.
摘要:
The intrastromal corneal ring (ICR) is adjustable in thickness and has an elongated, flexible, preferably transparent or translucent body which forms a circle. The ICR is of a size such that it can be inserted into a human eye and is comprised of a material which is compatible with human ocular tissue. The thickness of the ring can be adjusted so that it is not necessary to stock a plurality of different rings of different sizes to be used in connection with a method of adjusting the shape of the cornea of the eye. A plurality of different embodiments of ICRs are disclosed each of which are adjustable in terms of their thickness. The thickness may be adjusted prior to the insertion of the ICR into the cornea and may not be further adjustable after insertion. However, in accordance with preferred embodiments the ICR is inserted at a thickness which is believed to be proper and may thereafter be further adjusted in order to precisely define the desired thickness and thereby more precisely adjust the shape of the cornea and focus the light entering the eye on the retina.