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92 条记录 (耗时 0.038 秒)

    MATCHING A USER TO A CONVERSATION
    81.
    发明申请
    MATCHING A USER TO A CONVERSATION 有权
    匹配用户进行对话

    公开(公告)号：US20120310949A1

    公开(公告)日：2012-12-06

    申请号：US13149869

    申请日：2011-05-31

    申请人： Ira Cohen ,  Michal Aharon ,  Eli Mordechai

    发明人： Ira Cohen ,  Michal Aharon ,  Eli Mordechai

    IPC分类号： G06F17/30

    CPC分类号： G06F17/30699 ,  G06Q10/103

    摘要： A method for matching a user to a conversation includes, for each of a plurality of documents, mapping the document to one or more of a plurality of topics. The document is associated with a user. For each user, the user is mapped to each of the plurality of topics that are mapped to documents with which the user is associated. One of the users is matched to a conversation according to the mappings of the users to those of the plurality of topics that are also mapped to the conversation.

    摘要翻译： 用于将用户与对话相匹配的方法包括针对多个文档中的每一个将所述文档映射到多个主题中的一个或多个。 该文档与用户相关联。 对于每个用户，用户被映射到映射到用户与之关联的文档的多个主题中的每一个。 其中一个用户根据用户的映射与被映射到对话的多个主题的映射进行对话。

    Compositions and methods for detecting Borrelia afzelii
    84.
    发明申请
    Compositions and methods for detecting Borrelia afzelii 有权
    组织和检测方法

    公开(公告)号：US20120122092A1

    公开(公告)日：2012-05-17

    申请号：US13199093

    申请日：2011-08-18

    申请人： Melanie Feola ,  Martin Adelson ,  Eli Mordechai ,  Lisa Novak

    发明人： Melanie Feola ,  Martin Adelson ,  Eli Mordechai ,  Lisa Novak

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/689 ,  Y02A50/57

    摘要： Disclosed are oligonucleotides useful in methods for determining whether a sample contains Borrelia afzelii, a spirochete which is a causative agent of Lyme disease in humans. These oligonucleotides, which have nucleotide sequences derived from a coding segment of the gene encoding the p24 gene for the outer surface protein of Borrelia afzelii, are useful as forward and reverse primers for a polymerase chain reaction using nucleic acids from a biological sample as templates, and as probes for detecting any resultant amplicon. Detection of an amplicon indicates the sample contains Borrelia afzelii. Real-time PCR and detection using florescence resonance energy transfer is disclosed.

    摘要翻译： 公开了用于确定样品是否含有人类的莱姆病的致病因子的螺旋体（Borrelia afzelii）的方法中使用的寡核苷酸。 这些寡核苷酸具有衍生自编码b24基因的基因的编码区段的核苷酸序列，用于使用来自生物样品的核酸作为模板的聚合酶链反应的正向和反向引物， 以及用于检测任何所得扩增子的探针。 扩增子的检测表明样品含有Borrelia afzelii。 公开了使用荧光共振能量转移的实时PCR和检测。

    Compositions and methods for detecting cryptococcus neoformans
    86.
    发明授权
    Compositions and methods for detecting cryptococcus neoformans 有权
    用于检测隐球菌新生隐球菌的组合物和方法

    公开(公告)号：US07989186B2

    公开(公告)日：2011-08-02

    申请号：US12214317

    申请日：2008-06-18

    申请人： Melanie Feola ,  Martin Adelson ,  Eli Mordechai ,  John Entwistle

    发明人： Melanie Feola ,  Martin Adelson ,  Eli Mordechai ,  John Entwistle

    IPC分类号： C12P19/34

    CPC分类号： C12Q1/6895 ,  C07H21/04 ,  C12Q2600/158

    摘要： Disclosed are oligonucleotides useful in methods for determining whether a sample contains Cryptococcus neoformans, a causative agent for human cryptococcosis. These oligonucleotides, which have nucleotide sequences derived from a coding segment of the gene encoding the fungal specific transcription factor gene in Cryptococcus neoformans, are useful as forward and reverse primers for a polymerase chain reaction using nucleic acids from a biological sample as templates, and as probes for detecting any resultant amplicon. Detection of an amplicon indicates the sample contains Cryptococcus neoformans. Real-time PCR and detection using florescence resonance energy transfer is disclosed.

    摘要翻译： 公开了用于确定样品是否含有新隐球菌隐球菌（人类隐球菌病的致病因子）的方法中的寡核苷酸。 这些寡核苷酸具有源自编码新型隐球菌中的真菌特异性转录因子基因的基因的编码区的核苷酸序列，可用作使用来自生物样品的核酸作为模板的聚合酶链反应的正向和反向引物，以及 用于检测任何所得扩增子的探针。 扩增子的检测表明样品含有新型隐球酵母。 公开了使用荧光共振能量转移的实时PCR和检测。

    SYSTEM EVENT LOGS
    87.
    发明申请
    SYSTEM EVENT LOGS 有权
    系统事件日志

    公开(公告)号：US20110185234A1

    公开(公告)日：2011-07-28

    申请号：US12695780

    申请日：2010-01-28

    申请人： Ira Cohen ,  Michal Aharon ,  Eli Mordechai ,  Gilad Barash

    发明人： Ira Cohen ,  Michal Aharon ,  Eli Mordechai ,  Gilad Barash

    IPC分类号： G06F11/07

    CPC分类号： G06F11/3452 ,  G06F11/3476 ,  G06F17/30598 ,  G06F2201/81 ,  G06F2201/86

    摘要： An automated method of processing computer system event logs comprises receiving event messages associated with one or more system event logs, each event message including event text, determining a set of message clusters, each comprising a template text, representative of the event messages across the one or more event logs, and assigning each event message to a message cluster of the set, according to a measure of similarity between the respective event text of the event message and the template text of the message cluster.

    摘要翻译： 处理计算机系统事件日志的自动化方法包括接收与一个或多个系统事件日志相关联的事件消息，每个事件消息包括事件文本，确定一组消息集群，每个消息集群包括模板文本，代表一个事件消息 根据事件消息的相应事件文本与消息簇的模板文本之间的相似度的度量，将每个事件消息分配给该集合的消息集群。

    Antibodies specific to antigens of Bartonella henselae and use of these antigens in immunoassays
    89.
    发明授权
    Antibodies specific to antigens of Bartonella henselae and use of these antigens in immunoassays 有权
    对巴氏杆菌（Bartonella henselae）的抗原特异性抗体和在免疫测定中使用这些抗原的抗体

    公开(公告)号：US07727711B2

    公开(公告)日：2010-06-01

    申请号：US12075036

    申请日：2008-03-07

    申请人： Tera L. McCool ,  Chien Chang Loa ,  Eli Mordechai ,  Martin E. Adelson

    发明人： Tera L. McCool ,  Chien Chang Loa ,  Eli Mordechai ,  Martin E. Adelson

    IPC分类号： C12Q1/00 ,  G01N33/53 ,  A61K39/02

    CPC分类号： C07K16/12 ,  G01N33/56911

    摘要： Disclosed are antibodies that bind to the antigenic proteins GroES, RpIL, GroEL, SodB, UbiG, the ABC transporter, and an expressed antigenic protein of unknown function (the “BepA” protein) of Bartonella henselae, and use of these antigenic proteins in immunoassays in order to determine whether a sample from a subject contains one or more of these antibodies. Presence of such an antibody in the subject indicates that the subject is or was infected with Bartonella henselae, or indicates that the subject has an increased likelihood of being infected presently or in the past with Bartonella henselae. Also disclosed are kits for performing immunoassays, wherein each kit contains one or more of these antigenic proteins and also contains the reagents necessary for conducting an immunoassay.

    摘要翻译： 公开了结合抗原蛋白质GroES，RpIL，GroEL，SodB，UbiG，ABC转运蛋白和Bartonella henselae未知功能的表达抗原蛋白（“BepA”蛋白）的抗体，以及这些抗原蛋白在免疫测定中的用途 以确定来自受试者的样品是否含有这些抗体中的一种或多种。 受试者中存在这样的抗体表明受试者是或已被感染巴氏杆菌，或表明该受试者目前或过去与Bartonella henselae感染的可能性增加。 还公开了用于进行免疫测定的试剂盒，其中每个试剂盒含有这些抗原蛋白中的一种或多种，​​并且还含有进行免疫测定所必需的试剂。

    Methods and compositions for detecting and identifying species of Candida
    90.
    发明申请
    Methods and compositions for detecting and identifying species of Candida 有权

    公开(公告)号：US20080102449A1

    公开(公告)日：2008-05-01

    申请号：US11321984

    申请日：2005-12-29

    申请人： Jason Trama ,  Martin E. Adelson ,  Eli Mordechai

    发明人： Jason Trama ,  Martin E. Adelson ,  Eli Mordechai

    IPC分类号： C12Q1/68 ,  C12P19/34

    CPC分类号： C12Q1/6895 ,  C12Q1/689

    摘要： Methods and compositions useful in the detection and identification of species of Candida are disclosed. These species include Candida albicans, Candida glabrata, Candida parapsilosis, and Candida tropicalis, each of which is a causative agent for vaginal candidiasis. The compositions of the invention are combinations of oligonucleotides. These oligonucleotides include pairs of forward and reverse primers for polymerase chain reactions, wherein each primer pair is capable of priming the synthesis of an amplicon specific to one of Candida albicans, Candida glabrata, Candida parapsilosis, and Candida tropicalis, but preferably is not capable of priming the synthesis of an amplicon specific to any of the other three species. In preferred embodiments, the forward primers of the primer pairs have identical sequences, while each reverse primer of the primer pairs has a unique sequence relative to all of the other reverse primers; or the reverse primers of the primer pairs have identical sequences, while each forward primer of the primer pairs has a unique sequence relative to all of the other forward primers. These unique primer sequences account for the species specificity of the resultant amplicons. The oligonucleotides also include probes capable of detecting these amplicons, and sequencing primers for determining, in primer extension reactions, the nucleotide sequences contained within the amplicons. In preferred methods of the invention, a biological sample is tested for the presence of at least one isolate of Candida albicans, Candida glabrata, Candida parapsilosis, and Candida tropicalis by isolating nucleic acid from the sample, attempting a polymerase chain reaction in a mixture containing this nucleic acid and a plurality of these primer pairs, ascertaining whether any amplicon is produced in the mixture using an oligonucleotide probe, and determining the sequence of any resultant amplicon using the sequencing primers. The detection of an amplicon indicates that the sample contains at least one isolate of Candida albicans, Candida glabrata, Candida parapsilosis, or Candida tropicalis, and the nucleotide sequence data is used to determine which of these four Candida species is present.