-
公开(公告)号：US20070049526A1
公开(公告)日：2007-03-01
申请号：US11548805
申请日：2006-10-12
申请人： Penny Thompson , Katherine Lewis , Stephen Jaspers , Richard Garcia , Robert West , Susan Holderman , Chung Chan , Paul Sheppard , Anitra Wolf
发明人： Penny Thompson , Katherine Lewis , Stephen Jaspers , Richard Garcia , Robert West , Susan Holderman , Chung Chan , Paul Sheppard , Anitra Wolf
IPC分类号： A61K38/17
CPC分类号： G01N33/6893 , A61K38/1709 , C07K14/47 , C07K14/4702 , G01N2800/06 , G01N2800/065
摘要： The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods for treating intestinal motility disorders and improving gastrointestinal function with Zven1 and Zven2 polypeptides.
摘要翻译： 本发明提供使用Zven1和Zven2多肽来增加趋化因子产生的方法。 本发明还提供了用Zven1和Zven2多肽治疗肠蠕动障碍和改善胃肠功能的方法。
-
公开(公告)号：US20070048829A1
公开(公告)日：2007-03-01
申请号：US11550237
申请日：2006-10-17
申请人： Teresa Gilbert , Charles Hart , Paul Sheppard
发明人： Teresa Gilbert , Charles Hart , Paul Sheppard
IPC分类号： C12P21/06 , C07H21/04 , C07K14/475
CPC分类号： C04B38/06 , A61K38/177 , A61K38/18 , A61K38/1866 , A61K38/22 , C04B2111/00224 , C04B2111/00612 , C07K14/52 , C07K2319/00 , C12N2799/022 , C04B20/008 , C04B35/2641 , C04B35/50 , C04B35/64 , C04B38/0054 , C04B38/007 , C04B41/4578 , A61K2300/00
摘要： Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. The polypeptides comprise an amino acid segment that is at least 70% identical to residues 52-179 of SEQ ID NO:2 or residues 258-370 of SEQ ID NO:2. Multimers of the polypeptides are also disclosed. The polypeptides, multimeric proteins, and polynucleotides can be used in the study and regulation of cell and tissue development, as components of cell culture media, and as diagnostic agents.
-
公开(公告)号：US20070043210A1
公开(公告)日：2007-02-22
申请号：US11550887
申请日：2006-10-19
申请人： Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
发明人： Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
IPC分类号： C07K16/24
CPC分类号： A61K38/20 , A61K38/00 , C07K14/54 , C07K14/555 , C07K2319/00 , Y10S435/81 , Y10S435/975 , Y10S514/894
摘要： Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
-
公开(公告)号：US20070043209A1
公开(公告)日：2007-02-22
申请号：US11548108
申请日：2006-10-10
申请人： Paul Sheppard , Scott Presnell , Brian Fox , Teresa Gilbert , Betty Haldeman , Francis Grant
发明人： Paul Sheppard , Scott Presnell , Brian Fox , Teresa Gilbert , Betty Haldeman , Francis Grant
IPC分类号： C07K16/24
CPC分类号： C07K14/47 , C07K14/52 , C07K2319/00
摘要： The present invention relates to polynucleotide and polypeptide molecules for Zcyto21, an interferon-like protein, which is most closely related to interferon-α at the amino acid sequence level. The present invention also includes antibodies to the Zcyto21 polypeptides, and methods of using the polynucleotides and polypeptides.
摘要翻译： 本发明涉及用于Zcyto21的多核苷酸和多肽分子，干扰素样蛋白与氨基酸序列水平上的干扰素-α最相关。 本发明还包括对Zcyto21多肽的抗体，以及使用多核苷酸和多肽的方法。
-
公开(公告)号：US20070042471A1
公开(公告)日：2007-02-22
申请号：US11550661
申请日：2006-10-18
申请人： Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
发明人： Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
CPC分类号： A61K38/20 , A61K38/00 , C07K14/54 , C07K14/555 , C07K2319/00 , Y10S435/81 , Y10S435/975 , Y10S514/894
摘要： Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
-
公开(公告)号：US20070042470A1
公开(公告)日：2007-02-22
申请号：US11550585
申请日：2006-10-18
申请人： Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
发明人： Lowell Brady , Kevin Klucher , Chung Chan , Dennis Dong , Hong Liu , Paul Sheppard , Thomas Bukowski
CPC分类号： A61K38/20 , A61K38/00 , C07K14/54 , C07K14/555 , C07K2319/00 , Y10S435/81 , Y10S435/975 , Y10S514/894
摘要： Homogeneous preparations of IL-28A, IL-28B, and IL-29 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity. One type of biological activity that is shown is an antiviral activity.
-
公开(公告)号：US20060258586A1
公开(公告)日：2006-11-16
申请号：US11418803
申请日：2006-05-05
申请人： Paul Sheppard , Stephen Jaspers , Michael Stamm , Anitra Wolf , Jacob Kennedy
发明人： Paul Sheppard , Stephen Jaspers , Michael Stamm , Anitra Wolf , Jacob Kennedy
IPC分类号： C07K14/705 , A61K38/17
CPC分类号： C07K16/18 , A61K38/00 , C07K14/47 , C07K14/4702 , C07K14/523
摘要： The present invention provides methods of using Zsig98 polypeptides for treating intestinal motility disorders and improving gastrointestinal function, nutritient absorption, metabolism, and diabetes with Zsig98 polypeptides. The invention also provides methods for producing Zsig98 polynucleotides, polypeptides and antibodies.
摘要翻译： 本发明提供使用Zsig98多肽治疗肠蠕动障碍并通过Zsig98多肽改善胃肠功能，营养吸收，代谢和糖尿病的方法。 本发明还提供了生产Zsig98多核苷酸，多肽和抗体的方法。
-
公开(公告)号：US20060096611A1
公开(公告)日：2006-05-11
申请号：US10985100
申请日：2004-11-10
申请人： Nancy Leppla , Paul Sheppard , Roy Snider , Gerald Zinnbauer
发明人： Nancy Leppla , Paul Sheppard , Roy Snider , Gerald Zinnbauer
IPC分类号： A45D33/24
CPC分类号： A45D33/006
摘要： A cosmetic package is provided wherein the cover and container base are packaged in such a way as to allow a view of the product shade in the base at point of purchase.
摘要翻译： 提供了一种化妆品包装，其中盖子和容器底座以这样一种方式被包装，以便在购买点处允许在基部中的产品色调的视图。
-
公开(公告)号：US20060040360A1
公开(公告)日：2006-02-23
申请号：US11258647
申请日：2005-10-25
IPC分类号： C07K14/705 , C07H21/04
CPC分类号： C07K14/47 , A61K38/00 , C07K2319/00 , C12N2799/026
摘要： The present invention relates to polynucleotide and polypeptide molecules for zacrp7, a novel member of the family of proteins bearing a collagen-like domain and a Clq domain. The polypeptides and polynucleotides encoding them, are involved in homo and heterotrimerization or oligomerization and may be used in the study thereof. The present invention also includes antibodies to the zacrp7 polypeptides.
摘要翻译： 本发明涉及用于zacrp7的多核苷酸和多肽分子，其是具有胶原样结构域和Clq结构域的蛋白家族的新成员。 编码它们的多肽和多核苷酸参与同源和异三聚或寡聚化，并可用于其研究。 本发明还包括针对zacrp7多肽的抗体。
-
公开(公告)号：US20050255496A1
公开(公告)日：2005-11-17
申请号：US11013247
申请日：2004-12-15
申请人： Zeren Gao , Paul Sheppard , Brian Fox , James Holloway , Stephen Jaspers
发明人： Zeren Gao , Paul Sheppard , Brian Fox , James Holloway , Stephen Jaspers
IPC分类号： C07H21/04 , C07K14/525 , C07K14/715 , C07K16/24 , C12N15/09 , C12P21/02 , C12Q1/68 , G01N33/68
CPC分类号： C07K14/525 , A61K2039/505 , C07K14/7151 , C07K16/241 , C07K2317/34 , C07K2319/30 , C12Q1/6883 , C12Q2600/158 , G01N33/6863 , G01N2500/00
摘要： Novel tumor necrosis factor ligand polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptides may be used within methods relating to immune response, and may also be used in the development of immuno-regulatory therapeutics. Also provided are antibodies, binding proteins, agonists and antagonists of the ligand polypeptides.
摘要翻译： 公开了新型肿瘤坏死因子配体多肽，编码多肽的多核苷酸，以及相关的组合物和方法。 多肽可用于与免疫应答相关的方法中，并且也可用于开发免疫调节治疗。 还提供了配体多肽的抗体，结合蛋白，激动剂和拮抗剂。
-
-
-
-
-
-
-
-
-
搜索结果
97 条记录 (耗时 0.056 秒)
