公开(公告)号：US20080247503A1

公开(公告)日：2008-10-09

申请号：US12061357

申请日：2008-04-02

申请人： Guenter Lauritsch ,  Thomas Redel ,  Michael Zellerhoff

发明人： Guenter Lauritsch ,  Thomas Redel ,  Michael Zellerhoff

IPC分类号： A61B6/03

CPC分类号： A61B6/504 ,  A61B6/032 ,  A61B6/4441 ,  A61B6/481 ,  A61B6/507

摘要： A system and method of obtaining perfusion data for cerebral tissue is described. The system includes a C-arm X-ray device and a computing system configured to obtain sets of rotational projection X-ray data suitable for reconstructing 3D voxel data sets. A first data set is obtained of the patient, and then contrast material is injected into the vascular system to obtain a second 1 data set. A first voxel data set is subtracted from the second voxel data set, and the resultant data set is processed so as to segment the contrast-enhanced vasculature from the remaining data. The segmented voxels are subtracted from the resultant voxel data set, so as to yield a functional data set representing the difference between the attenuation of the tissues after administering contrast agent and the tissues prior to administering the contrast agent, without the contrast enhanced vasculature. The attenuation of the functional data set represents the perfusion or cerebral blood volume (CBV).

摘要翻译： 描述了获得脑组织灌注数据的系统和方法。 该系统包括C臂X射线装置和被配置为获得适于重建3D体元数据集的旋转投影X射线数据的组的计算系统。 获得患者的第一数据集，然后将造影材料注入血管系统以获得第二个1数据集。 从第二体素数据集中减去第一体素数据集，并且处理结果数据集，以便从剩余数据中分割对比度增强的脉管系统。 从所得到的体元数据集中减去分割体素，从而产生表示施用造影剂之前的组织的衰减与施用造影剂之前的组织之间的差异的功能数据集，而没有对比度增强的脉管系统。 功能数据集的衰减表示灌注或脑血容量（CBV）。

公开(公告)号：US20080132781A1

公开(公告)日：2008-06-05

申请号：US11607569

申请日：2006-11-30

申请人： Thomas Redel

发明人： Thomas Redel

IPC分类号： A61B5/055 ,  A61B5/026 ,  G06Q50/00 ,  G06K9/00

CPC分类号： G06Q50/22 ,  A61B5/02014 ,  A61B5/7275 ,  G06F19/00 ,  G16H40/63 ,  G16H50/50

摘要： A system and method provide an optimized workflow and a dedicated user interface for image visualizations that facilitate medical diagnosis. Image data may be acquired via an imaging procedure at a remote medical facility. A physician may review the images on a display and mark-up/modify the images via the interface to create user-defined data. The image and user-defined data may be transmitted to a service provider. At the service provider, a software technician may generate a medical simulation using the image and user-defined data. The medical simulation may simulate actual conditions within the patient. Subsequently, the simulation results may be transferred to, or otherwise remotely accessed via a network from, the remote medical facility. As a result, medical treatment provided by remote facilities, which may only have limited resources in terms of personnel and equipment, may be enhanced and inefficiencies associated with the generation of medical simulations may be alleviated.

摘要翻译： 系统和方法为图像可视化提供了优化的工作流程和专用的用户界面，便于医学诊断。 可以通过远程医疗设施处的成像过程获取图像数据。 医师可以查看显示器上的图像，并通过界面对图像进行标记/修改，以创建用户定义的数据。 图像和用户定义的数据可以被发送到服务提供商。 在服务提供商处，软件技术人员可以使用图像和用户定义的数据生成医学模拟。 医学模拟可以模拟患者内的实际情况。 随后，模拟结果可以通过远程医疗设施的网络传送到或者以其他方式远程访问。 因此，可以增强远程设施提供的治疗，这在人事和设备方面可能只有有限的资源，并且可以减轻与生成医学模拟有关的低效率。

公开(公告)号：US20070060995A1

公开(公告)日：2007-03-15

申请号：US11208188

申请日：2005-08-19

申请人： Oliver Meissner ,  Johannes Rieber ,  Thomas Redel

发明人： Oliver Meissner ,  Johannes Rieber ,  Thomas Redel

IPC分类号： A61F2/06

CPC分类号： A61M25/10 ,  A61B5/0066 ,  A61B5/0084 ,  A61B8/12 ,  A61F2/958

摘要： A method is provided for a workflow for cardiovascular intervention that provides online monitoring and therapy control of the procedure. A series of steps are provided utilizing an imaging technology in combination with a therapeutic device to optimize the reliability of the treatment and minimize the negative effects on the patient. In generally, the method steps include: positioning the therapeutic device, performing the therapeutic procedure while imaging the therapeutic device, providing a low pressure inflation of the therapeutic device, imaging the results of the therapeutic procedure, and assessing the result of the therapeutic procedure. If the assessment reveals that the therapeutic procedure result is not optimal, the therapeutic procedure is performed again and the steps thereafter are performed again.

摘要翻译： 为心血管介入工作流程提供了一种方法，提供在线监测和治疗过程控制。 利用成像技术与治疗装置组合来提供一系列步骤，以优化治疗的可靠性并最小化对患者的负面影响。 通常，方法步骤包括：定位治疗装置，在对治疗装置进行成像的同时执行治疗过程，提供治疗装置的低压充气，成像治疗过程的结果，以及评估治疗过程的结果。 如果评估显示治疗程序结果不是最佳的，则再次进行治疗程序，然后再次执行其后的步骤。

公开(公告)号：US20070038062A1

公开(公告)日：2007-02-15

申请号：US11478509

申请日：2006-06-29

申请人： Thomas Redel

发明人： Thomas Redel

IPC分类号： A61B5/05

CPC分类号： A61B5/6852 ,  A61B5/0066 ,  A61B5/1076

摘要： The invention relates to a device and a method for intraluminal imaging. The device features an imaging instrument and a transport unit, with which the imaging instrument is moved in a lumen at a defined speed over a defined distance. The device further features a rigid, i.e. mechanically-stable singly or multiply curved guide pipe, which has an internal diameter matched to the external diameter of the imaging instrument to accommodate and guide the imaging instrument and is made from a material which is transparent for the radiation or to the waves used in imaging. The guide pipe features at least one marking detectable with the imaging at a known position on the guide pipe and is mechanically connectable to the transport unit. The device and the method make it possible in a simple manner to record a 3D image data set from the intraluminal recorded 2D sectional images.

摘要翻译： 本发明涉及一种用于腔内成像的装置和方法。 该装置具有成像仪器和传送单元，成像仪器以规定的速度在限定的距离内以内腔移动成像仪器。 该装置还具有刚性，即机械稳定的单一或多重弯曲的导管，其具有与成像仪器的外径匹配的内径，以适应和引导成像仪器，并且由对于 辐射或成像中使用的波浪。 引导管具有至少一个可在引导管上的已知位置处通过成像检测的标记，并且可机械连接到输送单元。 该装置和方法使得可以以简单的方式从管腔内记录的2D截面图像记录3D图像数据集。

公开(公告)号：US20070015979A1

公开(公告)日：2007-01-18

申请号：US11484197

申请日：2006-07-11

申请人： Thomas Redel

发明人： Thomas Redel

IPC分类号： A61B5/00

CPC分类号： A61B5/0066 ,  A61B5/0084 ,  A61B5/6852 ,  A61B5/6853 ,  A61M25/0113 ,  A61M25/10184

摘要： The invention relates to a method for generating an image using optical coherence tomography, with a control device controlling the operation of an image generation device and a rinsing device automatically according to a predetermined program.

摘要翻译： 本发明涉及一种使用光学相干断层摄影技术生成图像的方法，控制装置根据预定程序自动控制图像生成装置和漂洗装置的操作。

公开(公告)号：US10828109B2

公开(公告)日：2020-11-10

申请号：US15809473

申请日：2017-11-10

申请人： Thomas Redel

发明人： Thomas Redel

IPC分类号： A61B34/10 ,  G16H20/40 ,  G16H30/40 ,  A61B6/00 ,  G16H50/50 ,  A61B90/00 ,  A61B8/06 ,  A61B8/08

摘要： A method for planning treatment of a stenosis in a vascular segment includes providing a geometric description of the vascular segment on a computer and determining a course of a hemodynamic parameter of the vascular segment along the vascular segment based on the geometric description provided by the computer. The computer calculates a mathematical derivative of the hemodynamic parameter over the length of the vascular segment along the vascular segment. At least one length section is specified for the vascular segment, and a value of the hemodynamic parameter in a distal end region of the vascular segment is simulated for a treatment device introduced virtually into the specified length section as a function of the mathematical derivative. The treatment of the stenosis including the introduction of the treatment device into the specified length section is planned as a function of the simulated value for the hemodynamic parameter.

公开(公告)号：US10664985B2

公开(公告)日：2020-05-26

申请号：US15881187

申请日：2018-01-26

申请人： Martin Berger ,  Thomas Redel

发明人： Martin Berger ,  Thomas Redel

IPC分类号： G06K9/00 ,  G06T7/60 ,  A61B5/02 ,  G06T7/00 ,  G06T11/00 ,  A61B6/00 ,  A61B5/055 ,  A61B5/00 ,  A61B5/026

摘要： Systems and methods are provided for evaluating the complexity of a stenosis or a section of a vessel. At least one image of the stenosis or the section of the vessel is provided. A geometrical feature value of the stenosis and/or or the section of the vessel is identified from the at least one image. At least one intensity feature value is determined based on a grey level intensity of the stenosis or the section of the vessel from the at least one image. A complexity value relating to the geometrical complexity of the stenosis or the section of the vessel is calculated as a function of the at least one geometrical feature value and the at least one intensity feature value of the stenosis or the section of the vessel.

公开(公告)号：US10157490B2

公开(公告)日：2018-12-18

申请号：US15685786

申请日：2017-08-24

申请人： Thomas Redel

发明人： Thomas Redel

IPC分类号： G06K9/00 ,  G06T15/08 ,  A61B90/00 ,  A61B6/03 ,  A61B6/00 ,  G06T7/33

摘要： A method and system for operating an x-ray device for a creation of a three-dimensional angiography of a body vessel segment. A three-dimensional reconstruction of the body vessel segment is provided to a computing device of the x-ray device. A center line of the body vessel segment is computed. An axis of rotation is laid through the center line. The three-dimensional reconstruction is registered with the x-ray device. The suitability of at least one recording angle pair with a first and a second recording angle for the creation of the three-dimensional angiography is assessed on the basis of an assessment criterion by the computing device. One of the at least one assessed recording angle pairs is selected for creation of the three-dimensional angiography as a function of a result of the assessment, in order to improve the creation of the three-dimensional angiography.

公开(公告)号：US09633454B2

公开(公告)日：2017-04-25

申请号：US14729961

申请日：2015-06-03

申请人： Günter Lauritsch ,  Thomas Redel ,  Michael Scheuering ,  Chris Schwemmer

发明人： Günter Lauritsch ,  Thomas Redel ,  Michael Scheuering ,  Chris Schwemmer

IPC分类号： G06K9/00 ,  G06T11/00 ,  A61B6/00 ,  G06T7/00 ,  G06T7/20 ,  G06T15/08 ,  A61B5/05

CPC分类号： G06T11/003 ,  A61B6/4441 ,  A61B6/481 ,  A61B6/486 ,  A61B6/504 ,  A61B6/507 ,  A61B6/5235 ,  A61B6/5264 ,  G06T7/0016 ,  G06T7/20 ,  G06T15/08 ,  G06T2207/10016 ,  G06T2207/10028 ,  G06T2207/10081 ,  G06T2207/10116 ,  G06T2207/30101 ,  G06T2207/30104 ,  G06T2211/404

摘要： A method for ascertaining a fluid-dynamic characteristic value of a resilient vascular tree, through which a fluid flows in a pulsating manner, is provided. At least one 2D projection, respectively, of the resilient vascular tree is generated by a projection device from different angles of projection, and a digital 3D reconstruction of the vascular tree is generated by an analysis device based on of the 2D projections. A geometry of at least one vessel of the resilient vascular tree is estimated based on the 3D reconstruction, and at least one fluid state in the resilient vascular tree is ascertained from the geometry and predetermined resilient properties of the resilient vascular tree. The at least one fluid-dynamic characteristic value is calculated as a function of the at least one fluid state.

公开(公告)号：US08755583B2

公开(公告)日：2014-06-17

申请号：US12729269

申请日：2010-03-23

申请人： Yu Deuerling-Zheng ,  Thomas Redel ,  Michael Zellerhoff

发明人： Yu Deuerling-Zheng ,  Thomas Redel ,  Michael Zellerhoff

IPC分类号： G01N23/04 ,  G06K9/00 ,  H05G1/08

CPC分类号： A61B6/504 ,  A61B6/481 ,  A61B6/507 ,  A61B6/5235 ,  A61B2090/364

摘要： A method and apparatus for generating at least one functional data set of a perfused region of the human or animal body are proposed. A first image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a first artery supplying the region. A second image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a second artery supplying the region. A first functional data set is generated by pixel-based calculation of at least one perfusion parameter from the first image data set. A second functional data set is generated by pixel-based calculation of at least one perfusion parameter from the second image data set.

摘要翻译： 提出了一种用于产生人体或动物身体的灌注区域的至少一个功能数据集的方法和装置。 提供第一图像数据组，其包括在将造影剂注射到供应该区域的第一动脉之前和之后的不同时间记录的灌注区域的至少两个图像。 提供第二图像数据集，其包括在将造影剂注射到供应该区域的第二动脉之前和之后的不同时间记录的灌注区域的至少两个图像。 通过基于来自第一图像数据集的至少一个灌注参数的基于像素的计算来生成第一功能数据集。 通过基于来自第二图像数据集的至少一个灌注参数的基于像素的计算来生成第二功能数据集。