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81.发明申请Aqueous photoprotective compositions comprising hydrophilic metal oxide nanopigments and polyalkylene glycols of low molecular mass 审中-公开包含亲水性金属氧化物纳米颜料和低分子量聚亚烷基二醇的水性光保护组合物公开(公告)号：US20070166248A1
公开(公告)日：2007-07-19
申请号：US11653394
申请日：2007-01-16
摘要： Stable, reduced whitening photoprotective compositions contain: a) at least one aqueous phase, b) at least hydrophilic inorganic nanopigments based on metal oxides, in an amount ranging from 1% to 25% by weight, with respect to the total weight of the composition, and c) at least one polyalkylene glycol having a molecular mass of less than 8,000 g/mol, formulated into d) a topically applicable, physiologically acceptable medium therefor.
摘要翻译： 稳定的减少美白光保护组合物包含：a）至少一个水相，b）至少基于金属氧化物的亲水性无机纳米颗粒，其量为组合物总重量的1重量％至25重量％ ，和c）至少一种分子量小于8,000g / mol的聚亚烷基二醇，配制成d）局部适用的生理学上可接受的介质。
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公开(公告)号：US20060030655A1
公开(公告)日：2006-02-09
申请号：US11248285
申请日：2005-10-13
CPC分类号： A61Q19/007 , A61K8/062 , A61K9/1075 , A61K2800/21 , A61K2800/262 , B01F17/0028 , B01F17/0085 , B82Y5/00
摘要： These objects and others may be accomplished with the present invention, the first embodiment of which provides an oil-in-water nanoemulsion, which includes: an oily phase dispersed in an aqueous phase; (i) at least one amphiphilic lipid selected from the group including nonionic amphiphilic lipids, anionic amphiphilic lipids, and combinations thereof; and (ii) at least one water-soluble nonionic polymer selected from the group including homopolymers and copolymers of ethylene oxide; polyvinyl alcohols; homopolymers and copolymers of vinylpyrrolidone; homopolymers and copolymers of vinylcaprolactam; homopolymers and copolymers of polyvinyl methyl ether; neutral acrylic homopolymers and copolymers; C1-C2 alkyl celluloses and their derivatives; C1-C3 alkyl guar; C1-C3 hydroxyalkyl guar; and combinations thereof; wherein a ratio of the weight of the oily phase to the weight of the amphiphilic lipid (i) ranges from 1.2 to 10; and wherein the oily phase includes oil globules having a number-average size of less than 100 nm. The nanoemulsion obtained is preferably transparent and stable on storage. It may form a composition for topical, preferably cosmetic or dermatological compositions, pharmaceutical compositions and ophthalmological compositions.
摘要翻译： 这些目的和其它目的可以用本发明来完成，本发明的第一个实施方案提供了一种水包油纳米乳液，其包括：分散在水相中的油相; （i）至少一种选自包括非离子两亲性脂质，阴离子两亲性脂质及其组合的两亲性脂质; 和（ii）至少一种选自包括环氧乙烷的均聚物和共聚物的水溶性非离子聚合物; 聚乙烯醇; 乙烯基吡咯烷酮的均聚物和共聚物; 乙烯基己内酰胺的均聚物和共聚物; 聚乙烯基甲基醚的均聚物和共聚物; 中性丙烯酸均聚物和共聚物; C 1 -C 2烷基纤维素及其衍生物; C 1 -C 3烷基瓜尔胶; C 1 -C 3羟烷基瓜尔胶; 及其组合; 其中所述油相的重量与所述两亲脂质（i）的重量的比率为1.2至10; 并且其中所述油相包括数均分子量小于100nm的油球。 获得的纳米乳液优选在储存时是透明的和稳定的。 它可以形成用于局部，优选化妆品或皮肤病学组合物，药物组合物和眼科学组合物的组合物。
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83.发明申请Process for dissolving lipophilic compounds in aqueous solution with amphiphilic block copolymers, and cosmetic composition 审中-公开用两亲性嵌段共聚物将亲油性化合物溶解在水溶液中的方法，以及化妆品组合物公开(公告)号：US20060024337A1
公开(公告)日：2006-02-02
申请号：US10529743
申请日：2003-10-16
IPC分类号： A61K8/81
CPC分类号： A61K8/0291 , A61K8/06 , A61K8/35 , A61K8/368 , A61K8/4966 , A61K8/63 , A61K8/90 , A61Q1/00 , A61Q13/00 , A61Q17/04 , A61Q19/00 , B01F17/0028 , B01F17/005 , B01F17/0057 , B01F17/0064 , B01F17/0071
摘要： The invention relates to a process for dissolving at least one lipophilic compound in at least one aqueous phase, characterized in that it comprises the step of associating the said lipophilic compound with an effective amount of at least one amphilic block copolymer comprising at least one ionic and/or at least one nonionic hydrophilic polymer block, and at least one hydrophobic polymer block.
摘要翻译： 本发明涉及一种在至少一个水相中溶解至少一种亲脂性化合物的方法，其特征在于其包括将所述亲脂性化合物与有效量的至少一种两亲嵌段共聚物缔合的步骤，所述两亲嵌段共聚物包含至少一种离子和/ /或至少一种非离子亲水性聚合物嵌段和至少一种疏水性聚合物嵌段。
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公开(公告)号：US20050249763A1
公开(公告)日：2005-11-10
申请号：US11105528
申请日：2005-04-14
CPC分类号： A61Q19/008 , A61K8/0208 , A61K2800/88 , A61Q19/00 , A61Q19/08
摘要： The present invention relates to kits for formulating a cosmetic product, containing an aqueous composition and at least one water-soluble anhydrous film, the aqueous composition and the film(s) being mixed together extemporaneously to form the cosmetic product.
摘要翻译： 本发明涉及用于配制化妆品的试剂盒，其含有水性组合物和至少一种水溶性无水膜，所述水性组合物和所述膜同时混合在一起以形成所述化妆品。
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公开(公告)号：US20050175651A1
公开(公告)日：2005-08-11
申请号：US11027993
申请日：2005-01-04
CPC分类号： A61K9/5146 , A61K9/5161 , A61K9/5192
摘要： The present invention relates to an aqueous dispersion of nanocapsules of core/shell type, in which: the core comprises at least one oil, the shell covering the core is of non-crosslinked polymeric nature and is water-insoluble and insoluble in the oil of the said core, the said nanocapsules having a mean size of less than or equal to 1 μm and having a degree of encapsulation of at least 8% by weight relative to the total weight of the said dispersion.
摘要翻译： 本发明涉及核/壳型纳米胶囊的水性分散体，其中：芯包含至少一种油，覆盖芯的壳具有非交联的聚合性质，并且是不溶于水且不溶于油的 所述芯，所述纳米胶囊具有小于或等于1μm的平均尺寸，并且相对于所述分散体的总重量具有至少8重量％的包封程度。
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86.发明申请Porous particles loaded with cosmetically or pharmaceutically active compounds 审中-公开加载化妆品或药物活性化合物的多孔颗粒公开(公告)号：US20050031699A1
公开(公告)日：2005-02-10
申请号：US10876527
申请日：2004-06-28
CPC分类号： A61K8/88 , A61K8/0279 , A61K8/25 , A61K2800/412 , A61K2800/56 , A61Q5/00 , A61Q5/02 , A61Q5/12 , A61Q19/00
摘要： The present invention relates to individualized porous particles, characterized in that they have a volume-average diameter of less than or equal to 10 μm and a specific surface area of greater than or equal to 1 m2/g, and in that they comprise at least one cosmetically or pharmaceutically active compound at least present inside said particles.
摘要翻译： 本发明涉及个体化多孔颗粒，其特征在于它们具有小于或等于10μm的体积平均直径和大于或等于1m 2 / g的比表面积，并且因为它们 包含至少一种至少存在于所述颗粒内的美容或药学活性化合物。
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87.发明授权Nanoemulsion based on ethylene oxide and propylene oxide block copolymers and its uses in the cosmetics, dermatological and/or ophthalmological fields 失效基于环氧乙烷和环氧丙烷嵌段共聚物的纳米乳液及其在化妆品，皮肤病学和/或眼科领域中的应用公开(公告)号：US06464990B2
公开(公告)日：2002-10-15
申请号：US09477715
申请日：2000-01-05
IPC分类号： A61K600
CPC分类号： B82Y5/00 , A61K8/062 , A61K8/90 , A61K9/0048 , A61K9/1075 , A61K31/77 , A61K2800/21 , A61K2800/413 , A61Q1/14 , B01F17/0028 , Y10S514/873 , Y10S514/937 , Y10S514/938
摘要： A nanoemulsion comprising an oily phase dispersed in an aqueous phase and having oil globules with a number-average size of less than 100 mm, which dispersion is facilitated by a surfactant comprised of polyethylene oxide and polypropylene oxide blocks, the oily phase comprising at least one oil having a molecular weight of greater than 400 and wherein the ratio by weight of the amount of oily phase to the amount of surfactant ranges from 2 to 10.
摘要翻译： 一种纳米乳液，其包含分散在水相中的油相，并且具有小于100mm的数均粒径的油球，所述分散体由包含聚环氧乙烷和聚环氧丙烷嵌段的表面活性剂促进，所述油相包含至少一种 分子量大于400的油，其中油相量与表面活性剂的重量比为2至10。
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88.发明授权Transparent nanoemulsion based on silicone surfactants and use in cosmetics or in dermopharmaceuticals 失效基于硅氧烷表面活性剂的透明纳米乳液，用于化妆品或皮肤药物
公开(公告)号：US6120778A
公开(公告)日：2000-09-19
申请号：US772724
申请日：1996-12-23
IPC分类号： A61K8/55 , A61K8/06 , A61K8/34 , A61K8/46 , A61K8/58 , A61K8/63 , A61K8/72 , A61K8/89 , A61K8/891 , A61K8/92 , A61K9/107 , A61K47/34 , A61Q3/02 , A61Q5/00 , A61Q19/00 , B01F17/54 , C08L83/12 , A61K7/00
CPC分类号： B82Y5/00 , A61K8/062 , A61K8/585 , A61K9/1075 , A61Q19/00 , A61K2800/21 , A61K2800/262 , A61K2800/413 , A61K47/34 , A61Q19/005 , A61Q19/008 , Y10S514/938
摘要： The present application relates to a transparent oil-in-water emulsion, the oil globules of which have a mean size of less than 100 nm, which comprises at least one silicone surfactant. The emulsion according to the invention is stable on storage and can contain significant amounts of oil while retaining good transparency. It can contain heat-sensitive active principles and can be used in particular in the cosmetics field and in dermatology for the treatment and the care of the skin, mucous membranes, nails, scalp and hair.
摘要翻译： 本申请涉及一种透明的水包油乳液，其油球的平均尺寸小于100nm，其包含至少一种硅氧烷表面活性剂。 根据本发明的乳液在储存时稳定，并且可以含有大量的油，同时保持良好的透明度。 它可以含有热敏性活性成分，特别可用于化妆品领域和皮肤科用于治疗和护理皮肤，粘膜，指甲，头皮和头发。
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89.发明授权Nanoparticles coated with a lamellar phase based on silicone surfactant and compositions containing them 失效基于硅氧烷表面活性剂和含有它们的组合物用层状相涂覆的纳米颗粒
公开(公告)号：US5919487A
公开(公告)日：1999-07-06
申请号：US771837
申请日：1996-12-23
IPC分类号： A61K8/55 , A61K8/02 , A61K8/04 , A61K8/11 , A61K8/14 , A61K8/58 , A61K8/63 , A61K8/64 , A61K8/67 , A61K8/72 , A61K8/81 , A61K8/89 , A61K8/894 , A61K8/898 , A61Q19/00 , A61Q19/08 , B01J13/22 , C08L83/12 , A61K9/16 , A61K9/50
CPC分类号： A61K8/894 , A61K8/11 , A61K8/671 , A61K8/678 , A61Q19/00 , A61Q19/08 , A61Q3/00 , A61Q5/00 , B01J13/22 , B82Y5/00 , A61K2800/412
摘要： The present invention relates to nanoparticles, and in particular nanocapsules, provided with a lamellar coating obtained from a silicone surfactant, and to their use in a composition, in particular a topical composition, for treatment of the skin, mucosae, nails, scalp and/or hair.
摘要翻译： 本发明涉及具有由硅氧烷表面活性剂获得的层状涂层的纳米颗粒，特别是纳米胶囊，以及它们在组合物，特别是局部组合物中的用途，用于治疗皮肤，粘膜，指甲，头皮和/ 或头发。
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90.发明授权Composition composed of an aqueous dispersion of stabilized vesicles of nonionic amphiphilic lipids 失效由非离子两亲性脂质稳定的囊泡的水性分散体组成的组合物
公开(公告)号：US5866158A
公开(公告)日：1999-02-02
申请号：US736936
申请日：1996-10-28
IPC分类号： A61K8/14 , A61K8/39 , A61K8/49 , A61K8/60 , A61K8/70 , A61K8/86 , A61Q1/02 , A61Q19/00 , A61Q19/08 , A61K9/127 , A61K7/00
CPC分类号： A61Q19/08 , A61K8/14 , A61K8/39 , A61K8/4973 , A61K8/4993 , A61K8/60 , A61K8/70 , A61K8/86 , A61Q19/00 , B82Y5/00 , A61Q1/02 , A61Q19/007 , Y10T428/2984
摘要： The vesicles are prepared from a lipid phase containing a mixture of nonionic amphiphilic lipids consisting of a mixture of esters of at least one polyol chosen from the group composed of polyethylene glycol containing from 1 to 60 ethylene oxide units, sorbitan, sorbitan bearing 2 to 60 ethylene oxide units, glycerol bearing 2 to 30 ethylene oxide units, polyglycerols containing 2 to 15 glycerol units, sucroses, and glucoses bearing 2 to 30 ethylene oxide units and of at least one fatty acid containing a saturated or unsaturated, linear or branched C.sub.5 -C.sub.17 alkyl chain, the number of alkyl chains per polyol group being between 1 and 10, the mixture being stabilized with ionic amphiphilic lipid or lipids chosen from the group composed of those which impart a pH of between 5.5 and 7.5 to the dispersion.
摘要翻译： 囊泡由含有由至少一种选自含有1至60个环氧乙烷单元的聚乙二醇组成的组中的至少一种多元醇的混合物组成的非离子两亲性脂质混合物的脂质相制备，脱水山梨醇，含有2-60个 环氧乙烷单元，含有2至30个环氧乙烷单元的甘油，含有2至15个甘油单元的聚甘油，含有2至30个环氧乙烷单元的蔗糖和葡萄糖，以及至少一种含有饱和或不饱和直链或支链C5- C17烷基链，每个多元醇基团的烷基链数在1和10之间，混合物用离子两亲性脂质或选自由赋予分散体5.5至7.5的pH组成的组中的脂质稳定。
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