公开(公告)号：US5725852A

公开(公告)日：1998-03-10

申请号：US526987

申请日：1995-09-12

Applicant: Yasutaka Igari ,  Minoru Yamada ,  Shigehisa Taketomi

Inventor： Yasutaka Igari ,  Minoru Yamada ,  Shigehisa Taketomi

IPC: A61K9/00 ,  A61K38/09 ,  A61K38/21 ,  A61K38/28 ,  A61K38/29 ,  A61K47/26

CPC classification number: A61K31/70 ,  A61K38/09 ,  A61K38/212 ,  A61K38/28 ,  A61K38/29 ,  A61K47/26 ,  A61K9/0019

Abstract: A transmucosal therapeutic composition comprising a physiologically active peptide or protein and a cytidine nucleotide derivative was produced. The above composition results in a satisfactory transmucosal absorption of physiologically active peptides or proteins which are otherwise hardly absorbed from the mucosa. Since it allows self-administration to the mucosa, such as the nasal, vaginal or digestive tract mucosa, in lieu of injection which causes pain, the invention is of great utility as a pharmaceutical dosage form for physiologically active peptides or proteins which must be administered over a protracted time.

Abstract translation: 制备包含生理活性肽或蛋白质和胞苷核苷酸衍生物的经粘膜治疗组合物。 上述组合物导致生理活性肽或蛋白质的令人满意的透粘膜吸收，否则几乎不会从粘膜吸收。 由于其允许对粘膜（例如鼻，阴道或消化道粘膜）的自身给药代替引起疼痛的注射，因此本发明作为必须施用的生理活性肽或蛋白质的药物剂型是非常有用的 在一段漫长的时间。

公开(公告)号：US5716640A

公开(公告)日：1998-02-10

申请号：US705348

申请日：1996-08-29

Applicant: Shigeru Kamei ,  Minoru Yamada ,  Yasuaki Ogawa

Inventor： Shigeru Kamei ,  Minoru Yamada ,  Yasuaki Ogawa

IPC: A61K9/50 ,  A61K9/16 ,  A61K9/52 ,  A61K38/06 ,  A61K38/09 ,  A61K38/21 ,  A61K47/34 ,  B01J13/02 ,  B01J13/04 ,  A61K9/48 ,  A61K9/14 ,  B32B5/16

CPC classification number: A61K38/212 ,  A61K38/066 ,  A61K38/09 ,  A61K9/1647 ,  A61K9/1694 ,  B01J13/02 ,  Y10S514/963 ,  Y10T428/2982 ,  Y10T428/2984 ,  Y10T428/2985

Abstract: A method of producing sustained-release microcapsules containing a biologically active substance from an W/O emulsion comprising an inner aqueous phase containing said biologically active substance and an external oil phase containing a biodegradable polymer, characterized in that microcapsules formed on microencapsulation of said biologically active substance with said biodegradable polymer are heated at a temperature not lower than the glass transition temperature of said biodegradable polymer but not so high as to cause aggregation of the microcapsules. This method enables the production of very useful sustained release microcapsules adapted to release a bologically active substance at a calculated rate over a protracted time period starting immediately following administration without an initial burst within one day following administration.

公开(公告)号：US5604840A

公开(公告)日：1997-02-18

申请号：US38839

申请日：1993-03-29

Applicant: Mitsuo Asai ,  Noboru Masuda ,  Moritoshi Yasunaga ,  Masayoshi Yagyu ,  Minoru Yamada ,  Katsunari Shibata

Inventor： Mitsuo Asai ,  Noboru Masuda ,  Moritoshi Yasunaga ,  Masayoshi Yagyu ,  Minoru Yamada ,  Katsunari Shibata

IPC: G06N3/04 ,  G06N3/063 ,  G06F15/18

CPC classification number: G06N3/063 ,  G06N3/0454

Abstract: An information processing apparatus is composed of an input layer, a hidden layer and an output layer, and performs a computation in terms of neuron models. In the information processing apparatus, a forward network comprising the input layer, the hidden layer and the output layer executes a computation for externally input data to determine the values of outputs therefrom, and a backward network comprising the output layer and the hidden layer executes computation for output values expected for given inputs to determine learning signal values. The information processing apparatus transfers the output values and learning values between the forward network and the backward network to modify the synapse weights of the neuron models.

Abstract translation: 信息处理装置由输入层，隐藏层和输出层构成，并且以神经元模型进行计算。 在信息处理装置中，包括输入层，隐藏层和输出层的正向网络对外部输入数据执行计算，以确定其输出值，并且包括输出层和隐藏层的反向网络执行计算 对于给定输入预期的输出值来确定学习信号值。 信息处理装置传送前向网络和后向网络之间的输出值和学习值，以修改神经元模型的突触权重。

公开(公告)号：US5462775A

公开(公告)日：1995-10-31

申请号：US399641

申请日：1995-03-07

Applicant: Minoru Yamada ,  Shingo Kawamura

Inventor： Minoru Yamada ,  Shingo Kawamura

IPC: C23C16/26 ,  C23C16/30 ,  C23C16/32 ,  B05D3/06

CPC classification number: C23C28/044 ,  C23C16/325 ,  Y10T428/31678

Abstract: A hard multilayer film structure comprises a titanium-containing compound layer possessing high wear resistance deposited on a substrate and a silicon-containing hard carbon layer possessing self-lubricating properties, high wear resistance and high resistance to heat. Deposition of these layers is effected by the plasma-enhanced chemical vapor deposition technique. As a raw gas for the deposition of silicon-containing hard carbon-layer, the gas containing tetramethyl silane or tetraethyl silane is used. Deposition of the silicon-containing hard carbon layer is carried out at a temperature of not more than 550.degree. C. and a pressure in the range of 0.05 to 0.5 Torr.

Abstract translation: 硬质多层膜结构包括具有沉积在基底上的高耐磨性的含钛化合物层和具有自润滑性，高耐磨性和高耐热性的含硅硬碳层。 这些层的沉积通过等离子体增强化学气相沉积技术来实现。 作为用于沉积含硅硬质碳层的原料气体，使用含有四甲基硅烷或四乙基硅烷的气体。 含硅硬质碳层的沉积在不高于550℃的温度和0.05-0.5乇范围内的压力下进行。

公开(公告)号：US5448775A

公开(公告)日：1995-09-12

申请号：US190592

申请日：1994-02-02

Applicant: Minoru Yamada ,  Kazuhiro Kume ,  Hideki Tsuruoka ,  Hisanobu Fugahashi ,  Robin Smith ,  John E. Schulte ,  Robert J. Ball ,  Robert J. Ready

Inventor： Minoru Yamada ,  Kazuhiro Kume ,  Hideki Tsuruoka ,  Hisanobu Fugahashi ,  Robin Smith ,  John E. Schulte ,  Robert J. Ball ,  Robert J. Ready

IPC: A63B71/14 ,  A41D13/08

CPC classification number: A63B71/143

Abstract: The present invention relates to a baseball glove having means located on a bottom palm portion for enhancing glove flexibility. The baseball glove includes a thumb stall, at least one finger stall, and a hand receiving opening. The glove includes a notch formed in a lower portion of the glove, and at least one slit formed in a web portion such that the notch and slits increase flexibility of the glove and facilitate opening and closing of the glove.

Abstract translation: 本发明涉及一种棒球手套，其具有位于底部手掌部分上的装置，用于提高手套的柔韧性。 棒球手套包括拇指档，至少一个手指档和一个手接收开口。 手套包括形成在手套的下部中的切口和形成在腹板部分中的至少一个狭缝，使得切口和狭缝增加手套的柔性并且有利于手套的打开和关闭。

公开(公告)号：US5335309A

公开(公告)日：1994-08-02

申请号：US87105

申请日：1993-07-01

Applicant: Koji Fujii ,  Nobuyuki Haji ,  Minoru Yamada

Inventor： Koji Fujii ,  Nobuyuki Haji ,  Minoru Yamada

IPC: B23K1/005 ,  B23K15/00 ,  B23K28/00 ,  H05B3/00 ,  H05B1/00

CPC classification number: B23K28/00 ,  B23K1/005 ,  B23K15/002 ,  H05B3/0038

Abstract: A light-beam heating apparatus utilizes light energy effectively by having a light emitting portion of a radiating lamp coincide with a first focal point of an ellipsoidal reflecting mirror automatically and with high accuracy Light intensity and positional information at a light receiving end of an optical fiber are detected by means of a photodetector, a light intensity signal converted by a photoelectric converter is inputted to an arithmetic drive circuit, a drive mechanism of a radiating lamp fitting mechanism is actuated, the light emitting portion of the radiating lamp is moved in the X-axis direction, the Y-axis direction and the Z-axis direction successively in a direction that the light intensity increases, a central axis of a distribution of light condensed by an ellipsoidal reflecting mirror and a central part of the light receiving end of the optical fiber are made to always coincide with each other so as to utilize the light energy effectively. The light energy incident to the optical fiber is computed from a light intensity signal and a detected position, and a lamp current is controlled so as to make the error with respect to an indicated value of a command circuit smaller, thereby to stabilize the light radiation energy at a predetermined value.

Abstract translation: 光束加热装置通过使辐射灯的发光部分自动和高精度地与椭圆反射镜的第一焦点重合而有效地利用光能。光强度和位于光纤的光接收端的位置信息 通过光电检测器检测到，由光电转换器转换的光强度信号被输入到运算驱动电路，驱动放射灯配合机构的驱动机构，将发光灯的发光部分移动到X 光轴方向，Y轴方向和Z轴方向依次沿光强度增加的方向，由椭圆体反射镜聚光的光的中心轴和光轴的光接收端的中心部分 使光纤总是相互重合，以有效地利用光能。 从光强度信号和检测位置计算入射到光纤的光能量，并且控制灯电流以使得关于命令电路的指示值的误差更小，从而稳定光辐射 能量处于预定值。

公开(公告)号：US5300405A

公开(公告)日：1994-04-05

申请号：US035399

申请日：1993-03-23

Applicant: Minoru Yamada ,  Junichi Kose ,  Shinichi Matsuda ,  Yasuhiro Kawai

Inventor： Minoru Yamada ,  Junichi Kose ,  Shinichi Matsuda ,  Yasuhiro Kawai

IPC: G03C5/26 ,  G03C5/38 ,  G03D3/00 ,  G03D15/02

CPC classification number: G03C5/26 ,  G03C5/38 ,  G03D15/022 ,  Y10S430/164

Abstract: Sheets of photosensitive material are processed through a processor comprising a series of developing, fixing, washing and drying sections, the drying section 14 including a plurality of conveyor rollers 42, a drive shaft operatively coupled to the rollers, and a plurality of nozzles 50 for injecting hot air against the traveling sheets. The rollers 42 and/or the nozzles 50 are arranged in the drying section so as to satisfy at least one of the relationships (1) and (2):k.sub.1 M+0.5

Abstract translation: 通过包括一系列显影，固定，洗涤和干燥部分的处理器处理感光材料片，干燥部分14包括多个输送辊42，可操作地连接到辊的驱动轴和多个喷嘴50 向旅行床上注入热空气。 辊子42和/或喷嘴50布置在干燥部分中以满足关系式（1）和（2）中的至少一个：k1M + 0.5

公开(公告)号：US5260107A

公开(公告)日：1993-11-09

申请号：US861246

申请日：1992-03-31

Applicant: Shingo Kawamura ,  Minoru Yamada

Inventor： Shingo Kawamura ,  Minoru Yamada

IPC: C23C16/26 ,  C23C16/30 ,  C23C16/32 ,  C23C16/34 ,  C23C28/04 ,  B05D3/06 ,  C23C16/00

CPC classification number: C23C16/30 ,  C23C16/32 ,  C23C16/34 ,  C23C28/04 ,  Y10T428/24942 ,  Y10T428/30

Abstract: This present invention provides a hard multilayer coated product comprising a hard wear-resistant titanium compound coating layer, a titanium compound layer having a compositional gradient and a self-lubricating coating layer comprising hard amorphous carbon as the principal component successively formed on the surface of a substrate, the first layer being formed at about 500.degree. C. by the plasma CVD method in a vacuum followed by the formation of the second and third layers at 250.degree. to 400.degree. C. in a vacuum maintained at the same level as above. The hard multilayer coated product is improved in wear-resistance and self-lubricity.

Abstract translation: 本发明提供一种硬质多层涂层制品，其包括硬质耐磨钛化合物涂层，具有组成梯度的钛化合物层和包含坚硬无定形碳作为主要成分的自润滑涂层， 基板，第一层通过等离子体CVD法在真空中在约500℃下形成，然后在与上述相同水平的250℃至400℃下形成第二层和第三层。 硬质多层涂层产品的耐磨性和自润滑性得到改善。

公开(公告)号：US5242982A

公开(公告)日：1993-09-07

申请号：US915396

申请日：1992-07-20

Applicant: Junji Oshima ,  Tatsuo Fujii ,  Minoru Yamada

Inventor： Junji Oshima ,  Tatsuo Fujii ,  Minoru Yamada

IPC: C08F285/00 ,  C08L67/02 ,  C08L69/00 ,  C08L77/00

CPC classification number: C08L67/02 ,  C08F285/00 ,  C08L69/00 ,  C08L77/00 ,  Y10S525/902

Abstract: This invention relates to a core-shell polymer comprising (a) a core having epoxy groups on the surface and (b) a shell on the core (a) having neither epoxy group nor functional groups that are reactive with epoxy group, compositions of engineering plastics which are excellent in impact strength at low temperature and the molded articles of the resin composition.

Abstract translation: 本发明涉及一种核 - 壳聚合物，其包含（a）在表面上具有环氧基的芯和（b）不具有环氧基的环氧基或不具有与环氧基反应的官能团的芯（a）上的壳，工程组成 低温冲击强度优异的塑料和树脂组合物的成型体。

公开(公告)号：US5217853A

公开(公告)日：1993-06-08

申请号：US921607

申请日：1992-08-03

Applicant: Minoru Yamada ,  Takashi Toyoda

Inventor： Minoru Yamada ,  Takashi Toyoda

IPC: G03C5/26 ,  G03C5/38

CPC classification number: G03C5/38 ,  G03C5/26 ,  Y10S430/164 ,  Y10S430/167

Abstract: A method for development processing of a silver halide photosensitive material using an automatic processor including at least the functions of development, fixing, washing and drying is disclosed, comprising using an alkaline developer containing a dialdehyde film hardening agent and carrying out the processing under conditions such that the running equilibrium pH of the fixer is at least 4.6.

Abstract translation: 公开了一种使用至少具有显影，定影，洗涤和干燥功能的自动处理器的卤化银感光材料的显影处理方法，该方法包括使用含有二醛膜硬化剂的碱性显影剂，并在如下条件下进行处理： 固定器的运行平衡pH至少为4.6。