公开(公告)号：US07709236B2

公开(公告)日：2010-05-04

申请号：US10530747

申请日：2003-10-09

申请人： Kengo Akimoto ,  Kenichi Higashiyama ,  Hiroshi Kawashima ,  Motoo Sumida

发明人： Kengo Akimoto ,  Kenichi Higashiyama ,  Hiroshi Kawashima ,  Motoo Sumida

IPC分类号： C12P7/64

CPC分类号： C12P7/6472 ,  A23D9/02

摘要： A process for producing a crude oil having lowered unsaponifiable matter content and/or ester-type sterol content and comprising a highly unsaturated fatty acid as a constituent fatty acid, characterized in that a microorganism capable of producing a fat or oil comprising an unsaturated fatty acid as a constituent fatty acid is cultured in a medium containing a nitrogen source concentration of 2 to 15% within a culture tank equipped with an agitation impeller satisfying the requirement that the ratio of the diameter of agitation impeller (=d) to the inner diameter of the culture tank (=D) is d/D=0.30 to 0.6.

摘要翻译： 一种生产具有降低的不皂化物质含量和/或酯类固醇含量并含有高度不饱和脂肪酸作为构成脂肪酸的原油的方法，其特征在于，能够生产包含不饱和脂肪酸的脂肪或油的微生物 作为构成脂肪酸，在含有浓度为2〜15％的氮源的培养基中培养，在配备有搅拌叶轮的培养槽中，搅拌叶轮满足搅拌叶轮直径（= d）与内径 培养罐（= D）为d / D = 0.30〜0.6。

公开(公告)号：US20090221105A1

公开(公告)日：2009-09-03

申请号：US12393087

申请日：2009-02-26

申请人： Masanobu Hishiki ,  Yaichiro Miura ,  Hiroshi Kawashima ,  Katsuhiro Mitsuda

发明人： Masanobu Hishiki ,  Yaichiro Miura ,  Hiroshi Kawashima ,  Katsuhiro Mitsuda

IPC分类号： H01L21/66 ,  H01L21/8238

CPC分类号： H01L21/26513 ,  H01L21/26586 ,  H01L21/823807 ,  H01L21/823814 ,  H01L21/823842 ,  H01L22/12 ,  H01L29/1083 ,  H01L2924/0002 ,  H01L2924/00

摘要： In mass production of CMIS integrated circuit devices or the like, electric characteristics, such as Vth (threshold voltage) or the like, disadvantageously vary due to variations in gate length of the MISFET. This problem has become serious because of a short channel effect. In order to solve the problem, various kinds of feed-forward techniques have been studied in which a subsequent variation factor process is regulated to be reversed with respect to variations in a previous variation factor process so as to cause these variation factors to cancel each other out. Since the feed-back technique has an effect of the cancellation process over the entire system, the technique can be relatively easily applied to a product with a single type of MISFE, but is difficult to be applied to a product equipped with a plurality of types of MISFETs. The invention is adapted to adjust the amount of halo implantation by multivariate analysis based on the result of a patterning step of the gate electrode and a film forming step of an offset spacer.

摘要翻译： 在大规模生产CMIS集成电路器件等时，诸如Vth（阈值电压）等的电特性由于MISFET的栅极长度的变化而不利地变化。 这个问题已经变得严重，因为通道效应很短。 为了解决这个问题，已经研究了各种前馈技术，其中随后的变化因子过程被调整为相对于先前的变化因子过程的变化而被反转，以使这些变化因子相互抵消 出来 由于反馈技术具有整个系统的取消处理的效果，因此该技术可以相对容易地应用于具有单一类型的MISFE的产品，但是难以应用于配备有多种类型的产品 的MISFETs。 本发明适用于基于栅电极的图案形成步骤和偏移间隔物的成膜步骤的结果，通过多元分析来调整光晕注入量。

公开(公告)号：US07492983B2

公开(公告)日：2009-02-17

申请号：US11659226

申请日：2005-08-04

申请人： Noritaka Matsubara ,  Hiroshi Kawashima ,  Kazutaka Nara

发明人： Noritaka Matsubara ,  Hiroshi Kawashima ,  Kazutaka Nara

IPC分类号： G02B6/12

CPC分类号： G02B6/126 ,  G02B6/12007 ,  G02B6/12019 ,  G02B6/274 ,  G02B6/2793 ,  G02B6/29352

摘要： The present invention provide an optical circuit device having: an optical circuit; a polarization beam splitter/combiner for splitting an incoming light beam into two polarization beams and combining the two polarization beams into an outgoing light beam; a first optical waveguide and a second optical waveguide for connecting the optical circuit and the polarization beam splitter/combiner and receiving the two polarization beams independently; and a polarization rotator, arranged on the first optical waveguide, for rotating a polarization plane of one of the two polarization beams split by the polarization beam splitter/combiner so as to match a polarization plane of the other of the two polarization beams, the optical circuit, the polarization beam splitter/combiner, the first optical waveguide, the second optical waveguide and the polarization rotator being integrated on a planar substrate.

摘要翻译： 本发明提供一种光电路装置，具有：光电路; 用于将入射光束分成两个偏振光束并将两个偏振光束组合成输出光束的偏振分束器/组合器; 第一光波导和第二光波导，用于连接光电路和偏振分束器/组合器并且独立地接收两个偏振光束; 以及偏振旋转体，设置在第一光波导上，用于旋转由偏振分束器/组合器分离的两个偏振光束之一的偏振面，以便匹配两个偏振光束中的另一个的偏振面，光学 电路，偏振分束器/组合器，第一光波导，第二光波导和偏振旋转器集成在平面基板上。

公开(公告)号：US20080240727A1

公开(公告)日：2008-10-02

申请号：US12042823

申请日：2008-03-05

申请人： Hiroshi Kawashima ,  Kazutaka Nara

发明人： Hiroshi Kawashima ,  Kazutaka Nara

IPC分类号： H04B10/12 ,  G02B6/26

CPC分类号： G02B6/12007 ,  G02B6/2713 ,  G02B6/2766 ,  G02B6/2934 ,  G02B6/29355 ,  G02B6/29394 ,  G02B6/29395 ,  G02B2006/12159 ,  H04B10/25133

摘要： The tunable dispersion compensator 10 of the present invention comprises: the Mach-Zehnder interferometers (MZIs) 21 to 25 cascaded on a planar lightwave circuit; and the tunable couplers 31 to 34 connected to between each corresponding pair of the MZIs respectively. The Y-branch waveguide 15 and 16 are used for connecting to between the MZIs 21, 25 as both end sides and the input/output optical waveguides 13, 14 respectively. The waveguide loop mirror 40 is connected to the final stage MZI 25 among the MZIs 21 to 25 which an incident light is propagated last therethrough. The half-wave plate 50 is inserted to the loop waveguide 41 of the waveguide loop mirror 40. And it becomes able to enhance (double) the amount of tunable dispersion because an input light signal is passed twice through the similar path by the waveguide loop mirror 40.

摘要翻译： 本发明的可调色散补偿器10包括：在平面光波电路上级联的马赫 - 曾德干涉仪（MZI）21至25; 以及可调谐耦合器31至34分别连接在每个对应的一对MZI之间。 Y分支波导15和16分别用作两端和输入/输出光波导13,14之间的MZI 21,25之间的连接。 波导环路镜40连接到最后通过其中传播入射光的MZI 21至25中的最后级MZI 25。 半波片50插入到波导环形反射镜40的环形波导41中。 并且由于输入光信号通过波导环路镜40相似的路径通过两次，所以能够增强（双倍）可调色散量。

公开(公告)号：US20080031566A1

公开(公告)日：2008-02-07

申请号：US11659226

申请日：2005-08-04

申请人： Noritaka Matsubara ,  Hiroshi Kawashima ,  Kazutaka Nara

发明人： Noritaka Matsubara ,  Hiroshi Kawashima ,  Kazutaka Nara

IPC分类号： G02B6/12

CPC分类号： G02B6/126 ,  G02B6/12007 ,  G02B6/12019 ,  G02B6/274 ,  G02B6/2793 ,  G02B6/29352

摘要： The present invention provide an optical circuit device having: an optical circuit; a polarization beam splitter/combiner for splitting an incoming light beam into two polarization beams and combining the two polarization beams into an outgoing light beam; a first optical waveguide and a second optical waveguide for connecting the optical circuit and the polarization beam splitter/combiner and receiving the two polarization beams independently; and a polarization rotator, arranged on the first optical waveguide, for rotating a polarization plane of one of the two polarization beams split by the polarization beam splitter/combiner so as to match a polarization plane of the other of the two polarization beams, the optical circuit, the polarization beam splitter/combiner, the first optical waveguide, the second optical waveguide and the polarization rotator being integrated on a planar substrate.

摘要翻译： 本发明提供一种光电路装置，具有：光电路; 用于将入射光束分成两个偏振光束并将两个偏振光束组合成输出光束的偏振分束器/组合器; 第一光波导和第二光波导，用于连接光电路和偏振分束器/组合器并且独立地接收两个偏振光束; 以及偏振旋转体，设置在第一光波导上，用于旋转由偏振分束器/组合器分离的两个偏振光束之一的偏振面，以便匹配两个偏振光束中的另一个的偏振面，光学 电路，偏振分束器/组合器，第一光波导，第二光波导和偏振旋转器集成在平面基板上。

公开(公告)号：US20070186226A1

公开(公告)日：2007-08-09

申请号：US11690440

申请日：2007-03-23

申请人： Kiyoshi Omori ,  Hidehiko Yamamoto ,  Masazumi Shiozawa ,  Hitoshi Taniguchi ,  Kazuya Sunami ,  Hiroshi Kawashima

发明人： Kiyoshi Omori ,  Hidehiko Yamamoto ,  Masazumi Shiozawa ,  Hitoshi Taniguchi ,  Kazuya Sunami ,  Hiroshi Kawashima

IPC分类号： G11B33/12 ,  G11B7/00

CPC分类号： G11B7/082 ,  G11B17/056

摘要： A disk recorder/player (1) including a skew adjusting means of a thin design is provided which includes a base (101), a disk rotation driving mechanism (102) for an optical disk (4), an optical pickup (103), first and second guide shafts (105, 106) to support the optical pickup (103) at opposite ends of the latter, an optical pickup moving means (104) guided by the first and second guide shafts (105, 106) in moving the optical pickup (103) radially of the optical disk (4), an elastic member (126) put in contact with the first and second guide shafts (105, 106) to force the first and second guide shafts (105, 106) in a direction generally perpendicular to the main side of the optical disk (4), an adjusting screw (127) put into contact with the first and second guide shafts (105, 106) from the opposite side of the elastic member (126) to move the first and second guide shafts (105, 106) in a direction opposite to the direction of forcing by the elastic member (126), and a skew adjusting means (109) which adjusts a skew, if any, by adjusting the inclination of the first and second guide shafts (105, 106) by the adjusting screw (127).

公开(公告)号：US20070099279A1

公开(公告)日：2007-05-03

申请号：US11606983

申请日：2006-12-01

申请人： Kengo Akimoto ,  Hiroshi Kawashima ,  Sakayu Shimizu

发明人： Kengo Akimoto ,  Hiroshi Kawashima ,  Sakayu Shimizu

IPC分类号： C12P7/64 ,  C12N1/16

CPC分类号： A61K31/202 ,  A23C9/1528 ,  A23C11/04 ,  A23D9/00 ,  A23K20/158 ,  A23L2/52 ,  A23L5/00 ,  A23L31/00 ,  A23L33/12 ,  A23L33/14 ,  A23V2002/00 ,  A61K8/14 ,  A61K8/92 ,  A61K8/925 ,  A61K8/99 ,  A61K31/201 ,  A61Q19/00 ,  C12P7/6472 ,  C12R1/645 ,  A23V2200/224 ,  A23V2250/18 ,  A23V2250/1862 ,  A23V2250/187 ,  A23V2250/1868

摘要： There are provided microorganisms having a property of producing a lipid containing unsaturated fatty acids as constituent fatty acids and extracellularly secreting the produced lipid encapsulated in lipid vesicles, methods of screening said microorganisms, as well as methods of efficiently producing a fatty acid-containing lipid using said microorganisms. Furthermore, there are provided lipid vesicles encapsulating a lipid containing unsaturated fatty acids, and foods, cosmetics, and animal feeds comprising said lipid vesicles added thereto. Artificially treated microorganisms or microorganisms collected from nature are grown on a solid medium, and microbial strains that form lipid vesicles at the periphery of the colonies and/or microbial strains that, when cultured in a transparent liquid medium, make the culture liquid cloudy are selected. The microorganisms obtained are cultured, lipid-containing lipid vesicles secreted in the culture liquid, are separated from the culture liquid, and the lipid is separated and purified.

公开(公告)号：US20070077638A1

公开(公告)日：2007-04-05

申请号：US11607032

申请日：2006-12-01

申请人： Kengo Akimoto ,  Hiroshi Kawashima ,  Sakayu Shimizu

发明人： Kengo Akimoto ,  Hiroshi Kawashima ,  Sakayu Shimizu

IPC分类号： C12P7/64 ,  C12N1/16

CPC分类号： A61K31/202 ,  A23C9/1528 ,  A23C11/04 ,  A23D9/00 ,  A23K20/158 ,  A23L2/52 ,  A23L5/00 ,  A23L31/00 ,  A23L33/12 ,  A23L33/14 ,  A23V2002/00 ,  A61K8/14 ,  A61K8/92 ,  A61K8/925 ,  A61K8/99 ,  A61K31/201 ,  A61Q19/00 ,  C12P7/6472 ,  C12R1/645 ,  A23V2200/224 ,  A23V2250/18 ,  A23V2250/1862 ,  A23V2250/187 ,  A23V2250/1868

摘要： There are provided microorganisms having a property of producing a lipid containing unsaturated fatty acids as constituent fatty acids and extracellularly secreting the produced lipid encapsulated in lipid vesicles, methods of screening said microorganisms, as well as methods of efficiently producing a fatty acid-containing lipid using said microorganisms. Furthermore, there are provided lipid vesicles encapsulating a lipid containing unsaturated fatty acids, and foods, cosmetics, and animal feeds comprising said lipid vesicles added thereto. Artificially treated microorganisms or microorganisms collected from nature are grown on a solid medium, and microbial strains that form lipid vesicles at the periphery of the colonies and/or microbial strains that, when cultured in a transparent liquid medium, make the culture liquid cloudy are selected. The microorganisms obtained are cultured, lipid-containing lipid vesicles secreted in the culture liquid, are separated from the culture liquid, and the lipid is separated and purified.

公开(公告)号：US20070077637A1

公开(公告)日：2007-04-05

申请号：US11606920

申请日：2006-12-01

申请人： Kengo Akimoto ,  Hiroshi Kawashima ,  Sakayu Shimizu

发明人： Kengo Akimoto ,  Hiroshi Kawashima ,  Sakayu Shimizu

IPC分类号： C12P7/64 ,  C12N1/16

CPC分类号： A61K31/202 ,  A23C9/1528 ,  A23C11/04 ,  A23D9/00 ,  A23K20/158 ,  A23L2/52 ,  A23L5/00 ,  A23L31/00 ,  A23L33/12 ,  A23L33/14 ,  A23V2002/00 ,  A61K8/14 ,  A61K8/92 ,  A61K8/925 ,  A61K8/99 ,  A61K31/201 ,  A61Q19/00 ,  C12P7/6472 ,  C12R1/645 ,  A23V2200/224 ,  A23V2250/18 ,  A23V2250/1862 ,  A23V2250/187 ,  A23V2250/1868

摘要： There are provided microorganisms having a property of producing a lipid containing unsaturated fatty acids as constituent fatty acids and extracellularly secreting the produced lipid encapsulated in lipid vesicles, methods of screening said microorganisms, as well as methods of efficiently producing a fatty acid-containing lipid using said microorganisms. Furthermore, there are provided lipid vesicles encapsulating a lipid containing unsaturated fatty acids, and foods, cosmetics, and animal feeds comprising said lipid vesicles added thereto. Artificially treated microorganisms or microorganisms collected from nature are grown on a solid medium, and microbial strains that form lipid vesicles at the periphery of the colonies and/or microbial strains that, when cultured in a transparent liquid medium, make the culture liquid cloudy are selected. The microorganisms obtained are cultured, lipid-containing lipid vesicles secreted in the culture liquid, are separated from the culture liquid, and the lipid is separated and purified.

摘要翻译： 提供了具有产生含有不饱和脂肪酸的脂质作为构成脂肪酸并细胞外分泌包封在脂质囊泡中的所产生的脂质的性质的微生物，筛选所述微生物的方法以及使用以下方法有效生产含脂肪酸的脂质： 说微生物。 此外，提供了包含含有不饱和脂肪酸的脂质的脂质囊泡，以及包含所述脂质囊泡的食品，化妆品和动物饲料。 人造处理的微生物或自然界收集的微生物在固体培养基上生长，并且在集落和/或微生物菌株的周围形成脂质囊泡的微生物菌株，当在透明液体培养基中培养时，选择培养液混浊 。 培养得到的微生物，分泌到培养液中的含有脂质的脂质囊泡与培养液分离，分离纯化脂质。

公开(公告)号：US20070072275A1

公开(公告)日：2007-03-29

申请号：US10569103

申请日：2004-08-20

申请人： Misa Ochiai ,  Hiroshi Kawashima ,  Sakayu Shimizu

发明人： Misa Ochiai ,  Hiroshi Kawashima ,  Sakayu Shimizu

IPC分类号： C12P7/64 ,  C12N15/74 ,  C12N1/18

CPC分类号： C12P7/6463 ,  C12N15/80

摘要： It is intended to provide a breeding method whereby a lipid-producing fungus belonging to the genus Mortierella can be effectively and efficiently bred without resort to antibiotics. Transformation is carried out with the use of an auxotroph (for example, uracil auxotroph) of a fungus belonging to the Mortierella as a host. More specically speaking, a gene compensating for the auxotrophy, which is employed as a marker, is transferred into the host (the gene transfer step). Next, a transformant is selected by using the recovery from the auxotrophy as the marker (the selection step). The lipid-producing fungus may be M. aplina, for example.

摘要翻译： 旨在提供一种育种方法，其中可以有效地和有效地繁殖属于被孢霉属的产生脂质的真菌而不诉诸抗生素。 使用属于被孢霉属的真菌的营养缺陷型（例如尿嘧啶营养缺陷型）作为宿主进行转化。 更具体地说，补充用作标记的营养缺陷型的基因被转移到宿主（基因转移步骤）中。 接下来，通过使用来自营养缺陷型的恢复作为标记来选择转化体（选择步骤）。 例如，产生脂质的真菌可以是甲基纤维素。