-
公开(公告)号:US6063596A
公开(公告)日:2000-05-16
申请号:US988876
申请日:1997-12-11
申请人: Preeti Lal , Olga Bandman , Jennifer L. Hillman , Henry Yue
发明人: Preeti Lal , Olga Bandman , Jennifer L. Hillman , Henry Yue
IPC分类号: G01N33/68 , A61K38/00 , A61K45/00 , A61P35/00 , A61P37/00 , C07K14/705 , C07K16/28 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , C12R1/19
CPC分类号: C07K14/705 , A61K38/00
摘要: The invention provides two human G-protein coupled receptors associated with immune response (GRIR) and polynucleotides which identify and encode GRIR. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of GRIR.
摘要翻译: 本发明提供了与免疫应答(GRIR)相关的两种人G-蛋白偶联受体和识别和编码GRIR的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与GRIR表达相关的疾病的方法。
-
公开(公告)号:US20050214795A1
公开(公告)日:2005-09-29
申请号:US10974440
申请日:2004-10-26
申请人: Jennifer Hillman , Olga Bandman , Preeti Lal , Henry Yue , Roopa Reddy , Y. Tang , Edward Gerstin , Chandra Arvizu , Mariah Baughn , Yalda Azimzai , Dyung M. Lu
发明人: Jennifer Hillman , Olga Bandman , Preeti Lal , Henry Yue , Roopa Reddy , Y. Tang , Edward Gerstin , Chandra Arvizu , Mariah Baughn , Yalda Azimzai , Dyung M. Lu
IPC分类号: C12N15/09 , A61K38/00 , A61K45/00 , A61P35/00 , A61P37/02 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12P21/02 , C12P21/08 , C12Q1/68 , C07H21/04 , C12N9/22
CPC分类号: C07K14/4702 , A61K38/00
摘要: The invention provides human transcriptional regulator molecules (HTRM) and polynucleotides which identify and encode HTRM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HTRM.
摘要翻译: 本发明提供了人转录调节分子(HTRM)和识别和编码HTRM的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HTRM表达相关的障碍的方法。
-
公开(公告)号:US20050130204A1
公开(公告)日:2005-06-16
申请号:US10986822
申请日:2004-11-15
申请人: Y. Tang , Preeti Lal , Olga Bandman , Henry Yue , Neil Corley , Karl Guegler , Gina Gorgone , Mariah Baughn , Chandra Patterson
发明人: Y. Tang , Preeti Lal , Olga Bandman , Henry Yue , Neil Corley , Karl Guegler , Gina Gorgone , Mariah Baughn , Chandra Patterson
IPC分类号: A61K38/00 , C07K14/47 , C12Q1/68 , C07H21/04 , C07K14/705
摘要: The invention provides human protein transport molecules (PTAM) and polynucleotides which identify and encode PTAM. The Invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of PTAM.
摘要翻译: 本发明提供鉴定和编码PTAM的人蛋白转运分子(PTAM)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与PTAM表达相关的障碍的方法。
-
公开(公告)号:US20050079575A1
公开(公告)日:2005-04-14
申请号:US10871385
申请日:2004-06-21
申请人: Jennifer Hillman , Olga Bandman , Y. Tang , Henry Yue , Preeti Lal , Neil Corley , Karl Guegler , Chandra Patterson
发明人: Jennifer Hillman , Olga Bandman , Y. Tang , Henry Yue , Preeti Lal , Neil Corley , Karl Guegler , Chandra Patterson
IPC分类号: C12N15/09 , A61K38/00 , A61K39/395 , A61K45/00 , A61P1/00 , A61P15/00 , A61P25/00 , A61P35/00 , A61P37/02 , A61P43/00 , C07K14/705 , C07K16/28 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , C07H21/04
CPC分类号: C07K14/705 , A61K38/00
摘要: The invention provides human receptor molecules (REC) and polynucleotides which identify and encode REC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of REC.
摘要翻译: 本发明提供了识别和编码REC的人受体分子(REC)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与REC表达相关的疾病的方法。
-
公开(公告)号:US20050260644A1
公开(公告)日:2005-11-24
申请号:US11099691
申请日:2005-04-06
申请人: Olga Bandman , Jennifer Hillman , Preeti Lal , Henry Yue , Y. Tang , Chandra Patterson , Mariah Baughn , Junming Yang
发明人: Olga Bandman , Jennifer Hillman , Preeti Lal , Henry Yue , Y. Tang , Chandra Patterson , Mariah Baughn , Junming Yang
IPC分类号: G01N33/53 , A61K38/00 , A61K45/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/68 , A61K38/17 , C07H21/04 , C12P21/06
CPC分类号: C07K14/4702 , A61K38/00
摘要: The invention provides human cell signaling proteins (CSIGP) and polynucleotides which identify and encode CSIGP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or prevention disorders associated with expression of CSIGP.
摘要翻译: 本发明提供了识别和编码CSIGP的人细胞信号蛋白(CSIGP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与CSIGP表达相关的障碍的方法。
-
公开(公告)号:US06475752B1
公开(公告)日:2002-11-05
申请号:US09364206
申请日:1999-07-30
申请人: Preeti Lal , Y. Tom Tang , Mariah R. Baughn , Matthew R. Kaser
发明人: Preeti Lal , Y. Tom Tang , Mariah R. Baughn , Matthew R. Kaser
IPC分类号: C12P2106
CPC分类号: C07K14/705
摘要: The invention provide a mammalian nucleic acid molecule and fragments thereof. It also provides for the use of the mammalian nucleic acid molecule for the characterization, diagnosis, evaluation, treatment, or prevention of conditions, diseases and disorders associated with its expression and for the production of a model system. The invention additionally provides expression vectors and host cells for the production of the protein encoded by the mammalian nucleic acid molecule. The invention further provides a mammalian protein or portions thereof. The invention still further provides for the use of the nucleic acid molecule and protein in assays to detect or purify ligands.
摘要翻译: 本发明提供哺乳动物核酸分子及其片段。 它还提供了哺乳动物核酸分子用于表征,诊断,评估,治疗或预防与其表达相关的病症和病症以及用于模型系统的生产的用途。 本发明另外提供用于产生由哺乳动物核酸分子编码的蛋白质的表达载体和宿主细胞。 本发明还提供哺乳动物蛋白质或其部分。 本发明还进一步提供核酸分子和蛋白质在测定中用于检测或纯化配体的用途。
-
公开(公告)号:US06916609B1
公开(公告)日:2005-07-12
申请号:US09501714
申请日:2000-02-10
申请人: Janice Au-Young , Preeti Lal , Olga Bandman
发明人: Janice Au-Young , Preeti Lal , Olga Bandman
IPC分类号: A01N37/18 , A61K38/00 , C07H21/04 , C07K1/00 , C07K14/47 , C12N1/21 , C12N15/09 , C12N15/21 , C12Q1/68
CPC分类号: C07K14/47 , A61K38/00 , Y10S530/827 , Y10S530/839
摘要: The invention provides a two new human DnaJ-like proteins (HSPJ1 or HSPJ2) and polynucleotides which identify and encode HSPJ1 or HSPJ2. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HSPJ1 or HSPJ2.
摘要翻译: 本发明提供两种新的人类DnaJ样蛋白(HSPJ1或HSPJ2)和识别和编码HSPJ1或HSPJ2的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与HSPJ1或HSPJ2表达相关的疾病的方法。
-
公开(公告)号:US5932445A
公开(公告)日:1999-08-03
申请号:US966316
申请日:1997-11-07
申请人: Preeti Lal , Janice Au-Young , Roopa Reddy , Lynn E. Murry , Preete Mathur
发明人: Preeti Lal , Janice Au-Young , Roopa Reddy , Lynn E. Murry , Preete Mathur
IPC分类号: A61K38/00 , A61K39/00 , C07K14/00 , C07K14/47 , C12N1/13 , C12N15/62 , C07H21/00 , C12N5/10 , C12N15/63
CPC分类号: C07K14/47 , C07K14/00 , C12N15/625 , A61K38/00 , A61K39/00 , C07K2319/036 , C07K2319/61
摘要: The invention provides signal peptide-containing proteins collectively designated SP, and polynucleotides which identify and encode these molecules. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention further provides methods for diagnosing, treating, and preventing disorders associated with expression of signal peptide-containing proteins.
摘要翻译: 本发明提供了统称为SP的含信号肽的蛋白质,以及鉴定和编码这些分子的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供用于诊断,治疗和预防与信号肽含蛋白质的表达相关的紊乱的方法。
-
公开(公告)号:US6043222A
公开(公告)日:2000-03-28
申请号:US388993
申请日:1999-09-02
申请人: Janice Au-Young , Preeti Lal , Olga Bandman
发明人: Janice Au-Young , Preeti Lal , Olga Bandman
IPC分类号: A01N37/18 , A61K38/00 , C07H21/04 , C07K1/00 , C07K14/47 , C12N1/21 , C12N15/09 , C12N15/21 , C12Q1/68
CPC分类号: C07K14/47 , A61K38/00 , Y10S530/827 , Y10S530/839
摘要: The invention provides a two new human DnaJ-like proteins (HSPJ1 or HSPJ2) and polynucleotides which identify and encode HSPJ1 or HSPJ2. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HSPJ1 or HSPJ2.
摘要翻译: 本发明提供两种新的人类DnaJ样蛋白(HSPJ1或HSPJ2)和识别和编码HSPJ1或HSPJ2的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与HSPJ1或HSPJ2表达相关的疾病的方法。
-
公开(公告)号:US5922567A
公开(公告)日:1999-07-13
申请号:US868288
申请日:1997-06-03
申请人: Janice Au-Young , Preeti Lal , Olga Bandman
发明人: Janice Au-Young , Preeti Lal , Olga Bandman
IPC分类号: A01N37/18 , A61K38/00 , C07H21/04 , C07K1/00 , C07K14/47 , C12N1/21 , C12N15/09 , C12N15/21 , C12Q1/68 , C12P21/06 , C12N1/20 , C12N15/00
CPC分类号: C07K14/47 , A61K38/00 , Y10S530/827 , Y10S530/839
摘要: The invention provides a two new human DnaJ-like proteins (HSPJ1 or HSPJ2) and polynucleotides which identify and encode HSPJ1 or HSPJ2. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HSPJ1 or HSPJ2.
摘要翻译: 本发明提供两种新的人类DnaJ样蛋白(HSPJ1或HSPJ2)和识别和编码HSPJ1或HSPJ2的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与HSPJ1或HSPJ2表达相关的疾病的方法。
-
-
-
-
-
-
-
-
-