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公开(公告)号:US20110053217A1
公开(公告)日:2011-03-03
申请号:US12457389
申请日:2009-06-09
申请人: Preeti Lal , Y. Tom Tang , Gina A. Gorgone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer L. Hillman , Olga Bandman
发明人: Preeti Lal , Y. Tom Tang , Gina A. Gorgone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer L. Hillman , Olga Bandman
IPC分类号: C12P21/00 , C07H21/04 , C12N1/21 , C07H21/02 , C07K14/435
CPC分类号: G01N33/57419 , A61K38/00 , A61K38/1709 , A61K39/3955 , A61K45/06 , C07K14/47 , C07K16/18 , C07K16/40 , C07K2317/76 , G01N2333/916
摘要: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
摘要翻译: 本发明提供了人信号肽肽蛋白(HSPP)和识别和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSPP表达相关的障碍的方法。
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公开(公告)号:US20050155089A1
公开(公告)日:2005-07-14
申请号:US10820474
申请日:2004-04-07
申请人: Preeti Lal , Y. Tang , Gina Gorgone , Neil Corley , Karl Guegler , Mariah Baughn , Ingrid Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer Hillman , Olga Bandman
发明人: Preeti Lal , Y. Tang , Gina Gorgone , Neil Corley , Karl Guegler , Mariah Baughn , Ingrid Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer Hillman , Olga Bandman
IPC分类号: G01N33/68 , A61K38/00 , A61K39/395 , A61K45/00 , A61P9/00 , A61P15/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , A01K67/00 , C07H21/04 , C12N9/64
CPC分类号: G01N33/57419 , A61K38/00 , A61K38/1709 , A61K39/3955 , A61K45/06 , C07K14/47 , C07K16/18 , C07K16/40 , C07K2317/76 , G01N2333/916
摘要: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
摘要翻译: 本发明提供了人信号肽肽蛋白(HSPP)和识别和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSPP表达相关的障碍的方法。
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公开(公告)号:US06916609B1
公开(公告)日:2005-07-12
申请号:US09501714
申请日:2000-02-10
申请人: Janice Au-Young , Preeti Lal , Olga Bandman
发明人: Janice Au-Young , Preeti Lal , Olga Bandman
IPC分类号: A01N37/18 , A61K38/00 , C07H21/04 , C07K1/00 , C07K14/47 , C12N1/21 , C12N15/09 , C12N15/21 , C12Q1/68
CPC分类号: C07K14/47 , A61K38/00 , Y10S530/827 , Y10S530/839
摘要: The invention provides a two new human DnaJ-like proteins (HSPJ1 or HSPJ2) and polynucleotides which identify and encode HSPJ1 or HSPJ2. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HSPJ1 or HSPJ2.
摘要翻译: 本发明提供两种新的人类DnaJ样蛋白(HSPJ1或HSPJ2)和识别和编码HSPJ1或HSPJ2的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与HSPJ1或HSPJ2表达相关的疾病的方法。
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公开(公告)号:US20050181415A1
公开(公告)日:2005-08-18
申请号:US11079743
申请日:2005-03-14
申请人: Junming Yang , Mariah Baughn , Neil Burford , Janice Au-Young , Dyung Lu , Roopa Reddy , Huijun Ring , Jennifer Hillman , Henry Yue , Yalda Azimzai , Monique Yao , Ameena Gandhi , Danniel Nguyen , Y. Tang , Preeti Lal , Olga Bandman
发明人: Junming Yang , Mariah Baughn , Neil Burford , Janice Au-Young , Dyung Lu , Roopa Reddy , Huijun Ring , Jennifer Hillman , Henry Yue , Yalda Azimzai , Monique Yao , Ameena Gandhi , Danniel Nguyen , Y. Tang , Preeti Lal , Olga Bandman
IPC分类号: A61K38/00 , A61K45/06 , C12N9/00 , C12Q1/26 , G01N33/68 , C12Q1/68 , A01K67/00 , C07H21/04 , C12N15/85
CPC分类号: C12Y101/01001 , A61K38/00 , A61K45/06 , C12N9/00 , C12Q1/26 , C12Y205/01018 , G01N33/6893 , G01N2500/00
摘要: The invention provides human drug metabolizing enzymes (DME) and polynucleotides which identify and encode DME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of DME.
摘要翻译: 本发明提供了人类代谢酶(DME)和识别和编码DME的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与DME的异常表达相关的紊乱的方法。
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公开(公告)号:US20050112565A1
公开(公告)日:2005-05-26
申请号:US10239032
申请日:2001-03-16
申请人: Henry Yue , Dyung Lu , Jennifer Policky , Angelo Delegeane , Catherine Tribouley , Farrah Khan , Janice Au-Young , Olga Bandman , Preeti Lal , Mark Borowsky , Ameena Gandhi , Jennifer Hillman , Y. Tang , Neil Burford , Mariah Baughn , Danniel Nguyen , Monique Yao , Narinder Walia , Ann He , April Hafalia , Yan Lu , Chandra Arvizu
发明人: Henry Yue , Dyung Lu , Jennifer Policky , Angelo Delegeane , Catherine Tribouley , Farrah Khan , Janice Au-Young , Olga Bandman , Preeti Lal , Mark Borowsky , Ameena Gandhi , Jennifer Hillman , Y. Tang , Neil Burford , Mariah Baughn , Danniel Nguyen , Monique Yao , Narinder Walia , Ann He , April Hafalia , Yan Lu , Chandra Arvizu
IPC分类号: A01H5/00 , A01H13/00 , A01H15/00 , A01K67/027 , A61K38/00 , A61K38/46 , A61K38/48 , A61K45/00 , A61K49/00 , A61P1/00 , A61P1/04 , A61P1/06 , A61P1/08 , A61P1/10 , A61P1/16 , A61P1/18 , A61P3/00 , A61P3/06 , A61P3/10 , A61P3/14 , A61P5/00 , A61P5/14 , A61P7/00 , A61P7/02 , A61P7/04 , A61P7/06 , A61P7/08 , A61P9/00 , A61P9/04 , A61P9/10 , A61P9/12 , A61P9/14 , A61P11/00 , A61P11/06 , A61P13/02 , A61P15/00 , A61P15/06 , A61P15/08 , A61P15/10 , A61P15/14 , A61P17/00 , A61P17/02 , A61P17/04 , A61P17/06 , A61P17/08 , A61P17/10 , A61P17/12 , A61P17/14 , A61P17/16 , A61P19/00 , A61P19/02 , A61P19/06 , A61P19/10 , A61P21/00 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/28 , A61P27/02 , A61P27/06 , A61P27/12 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P33/10 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/02 , A61P41/00 , A61P43/00 , C07H21/04 , C07K16/40 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/48 , C12N9/64 , C12N15/02 , C12N15/09 , C12N15/57 , C12P21/08 , C12Q1/02 , C12Q1/37 , C12Q1/68 , G01N33/15 , G01N33/50 , G01N33/53 , G01N33/566
CPC分类号: C12N9/48 , A01K2217/05 , A61K38/00 , C12N9/6421
摘要: The invention provides human proteases (PRTS) and polynucleotides which identify and encode PRTS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PRTS.
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公开(公告)号:US20050053987A1
公开(公告)日:2005-03-10
申请号:US10893888
申请日:2004-07-20
申请人: Preeti Lal , Karl Guegler , Gina Gorgone , Neil Corley , Mariah Baughn , Y. Tang , Jennifer Hillman , Olga Bandman , Yalda Azimzai , Janice Au-Young , Henry Yue , Dyung Lu , Junming Yang
发明人: Preeti Lal , Karl Guegler , Gina Gorgone , Neil Corley , Mariah Baughn , Y. Tang , Jennifer Hillman , Olga Bandman , Yalda Azimzai , Janice Au-Young , Henry Yue , Dyung Lu , Junming Yang
CPC分类号: C12N9/0004 , A61K38/00
摘要: The invention provides human oxidoreductase molecules (OXRE) and polynucleotides which identify and encode OXRE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of OXRE.
摘要翻译: 本发明提供人氧化还原酶分子(OXRE)和识别和编码OXRE的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与OXRE表达相关的障碍的方法。
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公开(公告)号:US20050048610A1
公开(公告)日:2005-03-03
申请号:US10874706
申请日:2004-06-24
申请人: Preeti Lal , Junming Yang , Henry Yue , Jennifer Jackson , Y. Tang , Olga Bandman , Neil Burford , Mariah Baughn , Yalda Azimzai , Dyung Lu , Janice Au-Young , Chandra Arvizu
发明人: Preeti Lal , Junming Yang , Henry Yue , Jennifer Jackson , Y. Tang , Olga Bandman , Neil Burford , Mariah Baughn , Yalda Azimzai , Dyung Lu , Janice Au-Young , Chandra Arvizu
IPC分类号: A61K38/00 , C07K14/47 , C07K14/705 , C07H21/04
CPC分类号: C07K14/705 , A01K2217/05 , A61K38/00 , C07K14/47
摘要: This invention relates to nucleic acid and amino acid sequences of human transport proteins and to the use of these sequences in the diagnosis, treatment, and prevention of transport, metabolic, neurological, cardiovascular, reproductive, and immune disorders, and cell proliferative disorders including cancer.
摘要翻译: 本发明涉及人类运输蛋白的核酸和氨基酸序列,以及这些序列用于诊断,治疗和预防运输,代谢,神经,心血管,生殖和免疫疾病以及包括癌症的细胞增殖性疾病 。
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公开(公告)号:US20050037466A1
公开(公告)日:2005-02-17
申请号:US10935190
申请日:2004-09-08
申请人: Janice Au-Young , Olga Bandman , Y. Tang , Henry Yue , Yalda Azimzai , Neil Burford , Mariah Baughn , Dyung Lu , Jennifer Hillman , Chandra Arvizu , Preeti Lal
发明人: Janice Au-Young , Olga Bandman , Y. Tang , Henry Yue , Yalda Azimzai , Neil Burford , Mariah Baughn , Dyung Lu , Jennifer Hillman , Chandra Arvizu , Preeti Lal
IPC分类号: A61K38/00 , C07K14/705 , C07K14/72 , C07H21/04
CPC分类号: C07K14/723 , A61K38/00 , C07K14/705
摘要: The invention provides human receptors and associated proteins (RECAP) and polynucleotides which identify and encode RECAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of RECAP.
摘要翻译: 本发明提供识别和编码RECAP的人受体和相关蛋白(RECAP)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与RECAP表达相关的疾病的方法。
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公开(公告)号:US20130244927A1
公开(公告)日:2013-09-19
申请号:US13397592
申请日:2012-02-15
申请人: Preeti Lal , Y. Tom Tang , Gina A. Gorgone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer L. Hillman , Olga Bandman
发明人: Preeti Lal , Y. Tom Tang , Gina A. Gorgone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer L. Hillman , Olga Bandman
CPC分类号: G01N33/57419 , A61K38/00 , A61K38/1709 , A61K39/3955 , A61K45/06 , C07K14/47 , C07K16/18 , C07K16/40 , C07K2317/76 , G01N2333/916
摘要: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
摘要翻译: 本发明提供了人信号肽肽蛋白(HSPP)和识别和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSPP表达相关的障碍的方法。
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公开(公告)号:US20080187961A1
公开(公告)日:2008-08-07
申请号:US11905820
申请日:2007-10-04
申请人: Preeti Lal , Y. Tom Tang , Gina A. Gorgone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer L. Hillman , Olga Bandman
发明人: Preeti Lal , Y. Tom Tang , Gina A. Gorgone , Neil C. Corley , Karl J. Guegler , Mariah R. Baughn , Ingrid E. Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer L. Hillman , Olga Bandman
CPC分类号: G01N33/57419 , A61K38/00 , A61K38/1709 , A61K39/3955 , A61K45/06 , C07K14/47 , C07K16/18 , C07K16/40 , C07K2317/76 , G01N2333/916
摘要: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
摘要翻译: 本发明提供了人信号肽肽蛋白(HSPP)和识别和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSPP表达相关的障碍的方法。
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