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141 条记录 (耗时 0.037 秒)

    Silicone hydrogels with amino surface groups
    83.
    发明授权
    Silicone hydrogels with amino surface groups 失效
    具有氨基表面基团的硅氧烷水凝胶

    公开(公告)号：US08119753B2

    公开(公告)日：2012-02-21

    申请号：US12242955

    申请日：2008-10-01

    申请人： Yu-Chin Lai ,  Weihong Lang

    发明人： Yu-Chin Lai ,  Weihong Lang

    IPC分类号： C08F30/08

    CPC分类号： C08J7/047 ,  C08J2383/08 ,  C08J2400/104 ,  C08J2400/105 ,  C08J2433/24 ,  C08L83/10 ,  G02B1/043 ,  C08L101/14

    摘要： A silicone hydrogel comprising monomeric units of one or more amino monomers, wherein the amino monomers are of formula IA, IB, IIA or IIB and monomeric units of one or more silicone monomers wherein R1, R2 and R3 are independently selected from hydrogen, C1-C6 alkyl or CH2OH; R4 is a C1-C10 alkyl optionally substituted with hydroxyl or carboxylic acid; E is a polymerizable group; X is an anion suitable for quaternary nitrogen; and n is 0, 1, 2, or 3 and m is an integer from 1 to 8.

    摘要翻译： 一种硅氧烷水凝胶，其包含一种或多种氨基单体的单体单元，其中所述氨基单体具有式IA，IB，IIA或IIB以及一种或多种硅氧烷单体的单体单元，其中R 1，R 2和R 3独立地选自氢，C1- C6烷基或CH2OH; R4是任选被羟基或羧酸取代的C1-C10烷基; E是可聚合基团; X是适合季氮的阴离子; n为0,1,2或3，m为1〜8的整数。

    Surface modified biomedical devices
    84.
    发明授权
    Surface modified biomedical devices 失效
    表面改性生物医学装置

    公开(公告)号：US08071660B2

    公开(公告)日：2011-12-06

    申请号：US12329694

    申请日：2008-12-08

    申请人： Weihong Lang ,  Yu-Chin Lai

    发明人： Weihong Lang ,  Yu-Chin Lai

    IPC分类号： G02C7/02 ,  C08F14/18 ,  A61F2/16

    CPC分类号： C08F220/22 ,  C08F220/26 ,  C08F230/08 ,  C08J7/047 ,  C08J2383/04

    摘要： A method for making a surface modified biomedical device is disclosed, the method comprising contacting a surface of a biomedical device with a copolymer which is the reaction product of one or more polymerizable polyhydric alcohols and one or more polymerizable fluorine-containing monomers.

    摘要翻译： 公开了一种制备表面改性生物医学装置的方法，所述方法包括使生物医学装置的表面与作为一种或多种可聚合多元醇和一种或多种可聚合含氟单体的反应产物的共聚物接触。

    Method for Making Surface Modified Biomedical Devices
    86.
    发明申请
    Method for Making Surface Modified Biomedical Devices 审中-公开
    制备表面改性生物医学装置的方法

    公开(公告)号：US20090111942A1

    公开(公告)日：2009-04-30

    申请号：US11924359

    申请日：2007-10-25

    申请人： Weihong Lang ,  Yu-Chin Lai ,  Daniel J. Hook

    发明人： Weihong Lang ,  Yu-Chin Lai ,  Daniel J. Hook

    IPC分类号： C08G63/48

    CPC分类号： A61L27/34 ,  A61L27/50 ,  A61L2400/18 ,  A61L2430/16 ,  C08J7/16

    摘要： Disclosed are methods for making a surface modified biomedical device involving (a) exposing a biomedical device having a plurality of biomedical device surface functional groups to one or more ethylenically unsaturated-containing organic compounds having a reactive group that is co-reactive to the biomedical device surface functional groups of the biomedical device; and (b) graft polymerizing a hydrophilic reactive monomer having a complementary reactive functionality with the ethylenically unsaturated functionalities of the ethylenically unsaturated-containing organic compounds on or near the surface of the biomedical device thus forming a biocompatible surface on the biomedical device. The methods disclosed are two-step methods and do not include any additional surface treatment steps.

    摘要翻译： 公开了用于制备表面改性生物医学装置的方法，其涉及（a）将具有多个生物医学装置表面官能团的生物医学装置暴露于具有与生物医学装置共反应的反应性基团的一种或多种含烯属不饱和的有机化合物 生物医学装置的表面官能团; 和（b）将具有互补反应性官能团的亲水性反应性单体与含烯属不饱和有机化合物的烯属不饱和官能团接枝聚合到生物医学装置的表面上或附近，从而在生物医学装置上形成生物相容性表面。 所公开的方法是两步法，不包括任何额外的表面处理步骤。

    Packaging Solutions
    90.
    发明申请
    Packaging Solutions 审中-公开
    包装解决方案

    公开(公告)号：US20080141628A1

    公开(公告)日：2008-06-19

    申请号：US11611307

    申请日：2006-12-15

    申请人： Weihong Lang ,  Yu-Chin Lai

    发明人： Weihong Lang ,  Yu-Chin Lai

    IPC分类号： B65B55/22 ,  B65B55/12 ,  B65B55/14 ,  B65D85/00

    CPC分类号： A61L12/04 ,  B65B25/008 ,  C11D3/0078 ,  C11D3/227

    摘要： The present invention is directed to new and improved packaging systems for storing ophthalmic devices such as contact lenses and to methods for packaging such ophthalmic devices with solutions to improve the comfort of the lenses during wear. In particular, the present invention is directed to a packaging system for storing an ophthalmic device in an aqueous packaging solution comprising hyaluronic acid or a salt thereof. Such solutions are retained on the surface of an unused lens for extended periods of time, resulting in surface modification that persists in the eye, which may provide significant improvement in the wetting properties of fresh contact lenses used for the first time and, moreover, even several hours after lens insertion, thereby preventing dryness and improving lubricity.

    摘要翻译： 本发明涉及用于存储诸如隐形眼镜的眼科装置的新的和改进的包装系统，以及用于包装这些眼科装置的方法，以提高穿戴期间镜片的舒适度。 特别地，本发明涉及用于将眼科装置储存在包含透明质酸或其盐的含水包装溶液中的包装系统。 这种溶液长时间保留在未使用的镜片的表面上，导致眼睛中持续存在的表面改性，这可以显着改善首次使用的新鲜隐形眼镜的润湿性能，此外甚至 镜片插入后数小时，从而防止干燥，提高润滑性。