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    Processes for generating halamine compounds on textile substrates to produce antimicrobial finish
    82.
    发明授权
    Processes for generating halamine compounds on textile substrates to produce antimicrobial finish 失效
    在纺织品基材上产生卤胺化合物以产生抗微生物剂的方法

    公开(公告)号：US07858539B2

    公开(公告)日：2010-12-28

    申请号：US11784711

    申请日：2007-04-09

    申请人： Ling Li ,  Shulong Li ,  Jeffrey S. Lane

    发明人： Ling Li ,  Shulong Li ,  Jeffrey S. Lane

    IPC分类号： B32B27/04

    CPC分类号： D06M13/33 ,  A01N25/10 ,  A01N25/34 ,  A01N59/00 ,  D06M13/325 ,  D06M13/35 ,  D06M13/352 ,  D06M13/355 ,  D06M15/3562 ,  D06M15/61 ,  D06M16/00 ,  Y10T442/2525 ,  A01N2300/00

    摘要： Provided herein are processes for topically applying an antimicrobial finish to a textile substrate, such as a yarn, a fabric, a composite, or an assembled article (for example, a garment). Specifically, the antimicrobial finish is based on hindered amine compounds that are applied in an aqueous bath (such as a commercial or home laundry setting), using the factors of pH and compound solubility to promote the formation of a durable antimicrobial halamine finish. Advantageously, the antimicrobial finish, which may be applied to fabrics made of any of a variety of fiber types and combinations of fiber types, has been found to be durable to repeated launderings.

    摘要翻译： 本文提供了将抗微生物整理剂局部施加到织物基底如纱线，织物，复合材料或组装制品（例如衣服）上的方法。 具体地说，抗微生物整理剂是以使用pH和化合物溶解度的因素促进形成持久的抗微生物胺盐酸盐处理剂为基础的受水胺化合物，其应用于水浴（例如商业或家庭洗衣设备）中。 有利地，已经发现可以应用于由各种纤维类型和纤维类型的组合制成的织物的抗微生物整理剂对于重复的洗涤是耐用的。

    MULTI-TARGETED RNAI THERAPEUTICS FOR SCARLESS WOUND HEALING OF SKIN
    83.
    发明申请
    MULTI-TARGETED RNAI THERAPEUTICS FOR SCARLESS WOUND HEALING OF SKIN 有权
    多用途无脊椎动物皮肤愈合治疗RNAI治疗

    公开(公告)号：US20100319074A1

    公开(公告)日：2010-12-16

    申请号：US12741645

    申请日：2008-11-06

    申请人： Patrick Y. Lu ,  Ling Li ,  Vera Simonenko

    发明人： Patrick Y. Lu ,  Ling Li ,  Vera Simonenko

    IPC分类号： A61K31/713 ,  C07H21/04 ,  A61P17/02 ,  A61K49/00

    CPC分类号： A61K31/7105 ,  C12N15/1136 ,  C12N15/1138 ,  C12N2310/14

    摘要： The present invention provides small interfering RNA (siRNA) molecules, compositions containing them, and methods of using them for improvement of skin scarless wound healing and other skin conditions, such as psoriasis and lupus-caused cutaneous lesions. The invention includes siRNA molecules and compositions containing them that inhibit the expression of one or more genes that promote pathological or undesired processes in wound healing and methods of using them.

    摘要翻译： 本发明提供小干扰RNA（siRNA）分子，含有它们的组合物，以及使用它们用于改善皮肤无伤口伤口愈合和其它皮肤状况的方法，例如牛皮癣和狼疮引起的皮肤损伤。 本发明包括siRNA分子和含有它们的组合物，其抑制一种或多种促进伤口愈合中病理或不期望过程的基因的表达以及使用它们的方法。

    Method and apparatus for curing a fiber having at least two fiber coating curing stages
    84.
    发明授权
    Method and apparatus for curing a fiber having at least two fiber coating curing stages 有权
    用于固化具有至少两个纤维涂层固化阶段的纤维的方法和设备

    公开(公告)号：US07322122B2

    公开(公告)日：2008-01-29

    申请号：US10208861

    申请日：2002-08-01

    申请人： Bob Overton ,  Ling Li

    发明人： Bob Overton ,  Ling Li

    IPC分类号： F26B19/00 ,  B05D3/02

    CPC分类号： C03C25/12 ,  B05D3/0209 ,  B05D3/067 ,  B05D2256/00 ,  B29C35/10 ,  B29C2035/0827 ,  B29L2011/0075

    摘要： The present invention provides a method and apparatus for curing a coated fiber, comprising either two fiber coating curing stages separated by a cooling stage, or two fiber coating curing stages separated by a distinct time interval, or both. One of the two fiber coating curing stages responds to the coated fiber, and provides a partially cured fiber coating. The other of the two fiber coating curing stages responds to the partially cured coated fiber for further curing the coating of the fiber. In one embodiment of the invention, a cooling stage is placed between the two curing stages, while in the other the curing stages are placed a set distance apart such that polymerization of the coating initiated by the first curing stage has time to complete prior to the coating being irradiated by the second curing stage. The cooling stage is used to actively remove heat generated during the cure process from the fiber coating, while the time delay is used to allow complete polymerization to occur before subsequent irradiations. These embodiments of the present invention can be used separately or in combination to achieve optimal fiber coating cure.

    摘要翻译： 本发明提供了一种用于固化涂覆纤维的方法和装置，包括由冷却阶段分离的两个纤维涂层固化阶段，或两个以不同时间间隔分开的两个纤维涂层固化阶段，或两者。 两个纤维涂层固化阶段之一响应于涂覆的纤维，并提供部分固化的纤维涂层。 两个纤维涂层固化阶段中的另一个响应于部分固化的涂覆纤维，以进一步固化纤维的涂层。 在本发明的一个实施方案中，将冷却阶段放置在两个固化阶段之间，而在另一个固化阶段中，固化阶段间隔一定距离放置，使得由第一固化阶段开始的涂层的聚合在第 涂层被第二固化阶段照射。 冷却阶段用于主动地从纤维涂层去除固化过程中产生的热量，而使用时间延迟以允许完全聚合在随后的照射之前发生。 本发明的这些实施方案可以单独使用或组合使用以实现最佳纤维涂层固化。

    Hindered amine treated textiles
    86.
    发明申请
    Hindered amine treated textiles 有权
    受阻胺处理的纺织品

    公开(公告)号：US20070092724A1

    公开(公告)日：2007-04-26

    申请号：US11256887

    申请日：2005-10-24

    申请人： Shulong Li ,  Ling Li

    发明人： Shulong Li ,  Ling Li

    IPC分类号： D02G3/00

    CPC分类号： D06M16/00 ,  D06M13/325 ,  D06M13/33 ,  D06M15/61 ,  Y10T428/249937 ,  Y10T428/2933 ,  Y10T442/20 ,  Y10T442/2025 ,  Y10T442/2525

    摘要： A treated textile material comprises a plurality of yarns or fibers having a hindered amine or halamine compound disposed on the exterior surface of the yarns or fibers and/or dispersed in the interior portion of the yarns or fibers. A treated textile material comprises a finish on a surface thereof, the finish comprising the product of a reaction between a cross-linking agent and a polymer comprising a plurality of secondary, hindered amine moieties attached to the polymer chain. Methods for making the treated textile materials are also described.

    摘要翻译： 经处理的纺织材料包括多个纱线或纤维，其具有设置在纱线或纤维的外表面上和/或分散在纱线或纤维内部的受阻胺或卤胺化合物。 经处理的纺织材料包括其表面上的整理剂，整理剂包含交联剂和包含连接到聚合物链上的多个仲的受阻胺部分的聚合物之间的反应的产物。 还描述了制备经处理的纺织材料的方法。

    Apparatus and methods for providing fault tolerance of networks and network interface cards
    88.
    发明授权
    Apparatus and methods for providing fault tolerance of networks and network interface cards 有权
    提供网络和网络接口卡容错的装置和方法

    公开(公告)号：US06308282B1

    公开(公告)日：2001-10-23

    申请号：US09188976

    申请日：1998-11-10

    申请人： Jiandong Huang ,  Ling Li ,  Sejun Song

    发明人： Jiandong Huang ,  Ling Li ,  Sejun Song

    IPC分类号： G06F1107

    CPC分类号： H04L69/40

    摘要： Methods and apparatus for implementation of fault-tolerant networks provide a network fault-tolerance manager for detecting failures and manipulating a node to communicate with an active channel. Failure detection incorporates one or more methods, including message pair and link pulse detection. Failure recovery includes switching all node data communications to a stand-by channel or switching just those nodes detecting a failure. Communication between nodes provides the distributed detection, with detecting nodes reporting failures to their network fault-tolerance manager and the network fault-tolerance manager broadcasting the failure recovery to all nodes. The network fault-tolerance manager is middleware, residing with each node in a logical hierarchy above a physical layer of a network and below a transport layer of the network. The approach is particularly suited to Ethernet LANs and capable of using commercial off-the-shelf network components.

    摘要翻译： 用于实现容错网络的方法和装置提供网络容错管理器，用于检测故障并操纵节点与活动信道进行通信。 故障检测包括一种或多种方法，包括消息对和链路脉冲检测。 故障恢复包括将所有节点数据通信切换到备用信道，或仅切换检测到故障的节点。 节点之间的通信提供分布式检测，检测节点向其网络容错管理器报告故障，网络容错管理器将故障恢复广播到所有节点。 网络容错管理器是中间件，驻留在网络物理层之上的逻辑层次中的每个节点，并且位于网络的传输层之下。 该方法特别适用于以太网LAN，并且能够使用商业现成的网络组件。

    5α-androstane-3β,5,6β-triol injection and preparation method therefor
    89.
    发明授权
    5α-androstane-3β,5,6β-triol injection and preparation method therefor 有权
    5α-雄甾烷-3和bgr，5,6和三烯注射液及其制备方法

    公开(公告)号：US09265837B1

    公开(公告)日：2016-02-23

    申请号：US14839869

    申请日：2015-08-28

    申请人： Guangmei Yan ,  Haiyan Hu ,  Jingxia Zhang ,  Pengxin Qiu ,  Ling Li ,  Ning Tian

    发明人： Guangmei Yan ,  Haiyan Hu ,  Jingxia Zhang ,  Pengxin Qiu ,  Ling Li ,  Ning Tian

    IPC分类号： A61K31/56 ,  A61K47/40 ,  A61K31/568 ,  A61K9/00

    CPC分类号： A61K47/40 ,  A61K9/0019 ,  A61K31/565 ,  A61K31/568 ,  A61K47/6951 ,  B82Y5/00

    摘要： A 5α-androstane-3β,5,6β-triol injection and its preparation are disclosed. The injection uses hydroxypropyl-β-cyclodextrin as a solubilizing agent and the active ingredient is present at a weight ratio of 1-20:40-500 to the hydroxypropyl-β-cyclodextrin. The injection may also comprise, by weight, 1-100 parts of at least one isotonic adjusting agent, 0-200 parts of at least one freeze drying filler, and 0-2000 parts of at least one solvent. The preparation method comprises dissolving hydroxypropyl-β-cyclodextrin solution, 5α-androstane-3β,5,6β-triol and at least one additional soluble excipient in water for injection in sequence to obtain a raw injection solution, and subjecting the raw injection solution to decolorization, depyrogenation, filtration and sterilization to obtain the injection. Drying the filtrate yields a solid for injection.

    摘要翻译： 公开了5α-雄甾烷-3＆bgr，5,6和三烯注射剂及其制备。 注射剂使用羟丙基 - 环糊精作为增溶剂，活性成分以1-20:40-500的重量比与羟丙基-β-环糊精一起存在。 注射剂还可以包含1-100份至少一种等渗调节剂，0-200份至少一种冷冻干燥填料和0-2000份至少一种溶剂。 该制备方法包括将羟丙基 - 环糊精溶液，5α-雄甾烷-3β，5,6α-三醇和至少一种额外的可溶性赋形剂在水中依次溶解，得到原始注射液， 注射溶液脱色，去热原，过滤和灭菌获得注射。 干燥滤液得到固体，用于注射。