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116 条记录 (耗时 0.039 秒)

    ALKALINE PROTEASE
    81.
    发明申请
    ALKALINE PROTEASE 有权
    碱性蛋白酶

    公开(公告)号：US20080177040A1

    公开(公告)日：2008-07-24

    申请号：US12049022

    申请日：2008-03-14

    申请人： Mitsuyoshi Okuda ,  Tsuyoshi Sato ,  Kazuhiro Saito ,  Nobuyuki Sumitomo ,  Yoshifumi Izawa ,  Katsuhisa Saeki ,  Tohru Kobayashi ,  Masafumi Nomura

    发明人： Mitsuyoshi Okuda ,  Tsuyoshi Sato ,  Kazuhiro Saito ,  Nobuyuki Sumitomo ,  Yoshifumi Izawa ,  Katsuhisa Saeki ,  Tohru Kobayashi ,  Masafumi Nomura

    IPC分类号： C07K2/00

    CPC分类号： C11D3/386 ,  C12N9/54 ,  C12Y304/21062

    摘要： Provided in the present invention is an alkaline protease wherein an amino acid residue at (a) position 65, (b) position 101, (c) position 163, (d) position 170, (e) position 171, (f) position 273, (g) position 320, (h) position 359 or (i) position 387 of SEQ. ID NO:1 or at a position corresponding thereto has been selected from the following amino acid residues: position (a): proline, position (b): asparagine, position (c): histidine, aspartic acid, phenylalanine, lysine, asparagine, serine, isoleucine, leucine, glutamine, threonine and valine, position (d): valine and leucine, position (e): alanine, glutamic acid, glycine and threonine, position (f): isoleucine, glycine and threonine, position (g): phenylalanine, valine, threonine, leucine, isoleucine and glycine, position (h): serine, leucine, valine, isoleucine and glutamine, position (i): alanine, lysine, glutamine, glutamic acid, arginine and histidine.The present invention makes it possible to efficiently produce and provide alkaline proteases having activity even in the presence of a highly concentrated fatty acid, and exhibiting excellent detergency for the removal of a complex stain containing protein, sebum and the like, and therefore being useful as an enzyme to be incorporated in a detergent.

    摘要翻译： 在本发明中提供的是碱性蛋白酶，其中（a）位置65，（b）位置101，（c）位置163，（d）位置170，（e）位置171，（f） ，（g）位置320，（h）位置359或（i）SEQ ID NO： 位置（a）：脯氨酸，位置（b）：天冬酰胺，位置（c）：组氨酸，天冬氨酸，苯丙氨酸，赖氨酸，天冬酰胺， 位置（d）：缬氨酸和亮氨酸，位置（e）：丙氨酸，谷氨酸，甘氨酸和苏氨酸，位置（f）：异亮氨酸，甘氨酸和苏氨酸，位置（g） 位置（h）：丝氨酸，亮氨酸，缬氨酸，异亮氨酸和谷氨酰胺，位置（i）：丙氨酸，赖氨酸，谷氨酰胺，谷氨酸，精氨酸和组氨酸，位置（h）：缬氨酸，缬氨酸，苏氨酸，亮氨酸，异亮氨酸和甘氨酸。 本发明使得可以有效地生产和提供具有活性的碱性蛋白酶，即使在高度浓缩的脂肪酸的存在下也具有优异的去污力来去除含有蛋白质，皮脂等的复合污渍，因此可用作 要掺入洗涤剂中的酶。

    Alkaline protease
    82.
    发明授权
    Alkaline protease 有权
    碱性蛋白酶

    公开(公告)号：US07101698B2

    公开(公告)日：2006-09-05

    申请号：US10456479

    申请日：2003-06-09

    申请人： Tsuyoshi Sato ,  Mitsuyoshi Okuda ,  Yasushi Takimura ,  Nobuyuki Sumitomo ,  Masafumi Nomura ,  Tohru Kobayashi

    发明人： Tsuyoshi Sato ,  Mitsuyoshi Okuda ,  Yasushi Takimura ,  Nobuyuki Sumitomo ,  Masafumi Nomura ,  Tohru Kobayashi

    IPC分类号： C12N9/54 ,  C12N15/74 ,  C12P21/00 ,  C07K14/32

    CPC分类号： C07H21/04 ,  C12N9/54

    摘要： The present invention relates to an alkaline protease having a prepro sequence, wherein the prepro sequence is a mutant sequence of the amino acid sequence of SEQ ID NO: 1 or an amino acid sequence having 80% or higher homology to the amino acid sequence of SEQ ID NO: 1, in which amino acid residues at (a) position 52, (b) position 75, and (c) position 142 of SEQ ID NO: 1, or amino acid residues at positions corresponding to these positions are substituted by the following amino acid residues: at position (a): aspartic acid or arginine, at position (b): alanine or arginine, and at position (c): lysine; and the alkaline protease, when in a mature form, has the amino acid sequence of SEQ ID NO: 2 or an amino acid sequence having a homology of 80% or higher to this amino acid sequence. The present invention also relates to, for example, a gene encoding the alkaline protease. According to the present invention, an alkaline protease increased in production can be produced. In particular, there can be efficiently produced an alkaline protease having an activity even in the presence of a fatty acid of high concentration and exhibiting excellent detergency against complex soils containing proteins and sebum.

    摘要翻译： 本发明涉及具有前序列的碱性蛋白酶，其中前序列是SEQ ID NO：1的氨基酸序列的突变序列或与SEQ ID NO：1的氨基酸序列具有80％以上同源性的氨基酸序列 SEQ ID NO：1的（a）位置52，（b）位置75和（c）位置142处的氨基酸残基或对应于这些位置的位置处的氨基酸残基被替换为SEQ ID NO： 以下氨基酸残基：位置（a）：天冬氨酸或精氨酸，位置（b）：丙氨酸或精氨酸，和位置（c）：赖氨酸; 碱性蛋白酶以成熟形式具有SEQ ID NO：2的氨基酸序列或与该氨基酸序列同源性为80％以上的氨基酸序列。 本发明还涉及例如编码碱性蛋白酶的基因。 根据本发明，可以生产生产中增加的碱性蛋白酶。 特别是，即使在高浓度的脂肪酸的存在下也能够有效地生成具有活性的碱性蛋白酶，并且对于含有蛋白质和皮脂的复杂土壤表现出优异的去污力。

    Dithia-s-indacene derivative
    84.
    发明申请
    Dithia-s-indacene derivative 审中-公开
    二硫杂萘衍生物

    公开(公告)号：US20050258398A1

    公开(公告)日：2005-11-24

    申请号：US11115375

    申请日：2005-04-27

    申请人： Tohru Kobayashi ,  Yoshiki Hasegawa

    发明人： Tohru Kobayashi ,  Yoshiki Hasegawa

    IPC分类号： G02F1/13 ,  C07D495/02 ,  C07D495/04 ,  C09K19/02 ,  C09K19/34 ,  H01L51/50 ,  H05B33/14 ,  H05B33/22

    CPC分类号： C07D495/04 ,  C09K19/3491

    摘要： A 1,5-dithia-s-indacene or 1,7-dithia-s-indacene derivative represented by general formula (1): wherein R1 and R2 each independently represents a hydrogen atom, an alkyl group or an alkoxy group; R3-R12 each independently represents a hydrogen atom, an alkyl group, an alkoxy group, a halogen atom or a cyano group; either of X1 and X2 represents a sulfur atom while the other represents a carbon atom; either of X3 and X4 represents a sulfur atom while the other represents a carbon atom; R13, R14, R15 or R16 is present only in the case where X1, X2, X3 or X4, respectively, is a carbon atom, and R13, R14, R15 or R16 each independently represents a hydrogen atom, an alkyl group or a halogen atom; and a broken line independently indicates a double bond in the case where X1, X2, X3 or X4 to which the broken line is connected represents a carbon atom or a broken line independently indicates a single bond in case X1, X2, X3 or X4 to which the broken line is connected represents a sulfur atom. A liquid crystal composition comprising the 1,5-dithia-s-indacene or 1,7-dithia-s-indacene derivative represented by the general formula (1). An electronic device comprising the liquid crystal composition.

    摘要翻译： 由通式（1）表示的1,5-二硫代顺 - 或1,5-二硫代 - 顺 - 并吲哚衍生物：其中R 1和R 2各自 独立地表示氢原子，烷基或烷氧基; R 3〜R 12各自独立地表示氢原子，烷基，烷氧基，卤素原子或氰基; X 1和X 2中的任一个表示硫原子，而另一个表示碳原子; X 3和X 4中的任一个表示硫原子，而另一个表示碳原子; R 13，R 14，R 15或R 16只存在于X < 1，X 2，X 3或X 4分别是碳原子，R 13， R 14，R 15或R 16各自独立地表示氢原子，烷基或卤素原子; 在X 1，X 2，X 3或X 4的情况下，虚线独立地表示双键， SUP>连接的虚线表示碳原子或虚线独立地表示在X 1，X 2，X 3， / SUP>或X 4连接的X 4代表硫原子。 一种液晶组合物，其包含由通式（1）表示的1,5-二硫代 - 顺 - 原油或1,7-二硫代 - 顺/并吲哚衍生物。 一种包含液晶组合物的电子器件。

    Plastic film having a coating layer comprising a copolyester and a conductive polymer and light-sensitive photographic material using the same
    89.
    发明授权
    Plastic film having a coating layer comprising a copolyester and a conductive polymer and light-sensitive photographic material using the same 失效
    具有包含共聚酯和导电聚合物的涂层的塑料膜和使用其的感光照相材料

    公开(公告)号：US5334457A

    公开(公告)日：1994-08-02

    申请号：US757247

    申请日：1991-09-10

    申请人： Yoshihiro Wada ,  Tohru Kobayashi ,  Noriki Tachibana

    发明人： Yoshihiro Wada ,  Tohru Kobayashi ,  Noriki Tachibana

    IPC分类号： C08J7/04 ,  G03C1/89 ,  G03C1/93 ,  B32B27/06

    CPC分类号： C08J7/047 ,  G03C1/89 ,  G03C1/93 ,  C08J2367/02 ,  C08J2423/06 ,  Y10S430/109 ,  Y10S430/128 ,  Y10T428/31786 ,  Y10T428/31794

    摘要： There are disclosed a plastic resin film which comprises a polyester resin composition comprising at least two components of (A) a polyester copolymer and (B) a polymer having conductivity, preferably having a number average molecular weight of 500 to 5000, being laminated on at least one surface of a plastic film support; a light-sensitive photographic material which comprises at least one silver halide emulsion layer being laminated on said film laminate or plastic film; and a method for preparing a plastic film which comprises coating an aqueous solution of the polyester resin composition on at least one surface of a non-oriented plastic film support or uniaxially oriented plastic film support, stretching the coated support to at least monoaxial direction and then completing orientation crystallization.

    摘要翻译： 公开了一种塑料树脂膜，其包含聚酯树脂组合物，其包含（A）聚酯共聚物和（B）具有导电性，优选数均分子量为500至5000的聚合物的至少两种组分，层压在 塑料薄膜支架的最少一个表面; 一种感光照相材料，其包含层压在所述薄膜层压体或塑料薄膜上的至少一个卤化银乳剂层; 以及一种制备塑料膜的方法，该方法包括将聚酯树脂组合物的水溶液涂覆在非取向塑料薄膜载体或单轴取向塑料薄膜载体的至少一个表面上，将涂覆的载体拉伸至至少单轴方向，然后 完成定向结晶。