Method for the detection and/or determination of a polyvalent antigen
using at least two different monoclonal antibodies
    81.
    发明授权
    Method for the detection and/or determination of a polyvalent antigen using at least two different monoclonal antibodies 失效
    使用至少两种不同单克隆抗体检测和/或测定多价抗原的方法

    公开(公告)号:US4471058A

    公开(公告)日:1984-09-11

    申请号:US401642

    申请日:1982-07-26

    摘要: A method for the detection and/or determination of an antigen having at least two separate antibody combining sites or antigenic determinants (i.e. a polyvalent antigen) using at least two different monoclonal antibodies which bind to the separate sites is described. In particular the method utilizes Protein A with a carrier to immobilize a first monoclonal antibody which in turn, can bind to one antigenic determinant on the antigen. The second antibody with a label is provided in a solution and binds to the second antigenic determinant on the antigen. A test kit is described for practicing the method. Novel anti-PGH synthase and anti-PGI.sub.2 synthase antibodies and hybridoma cells producing such antibodies are described.

    摘要翻译: 描述了使用至少两种结合分离位点的不同单克隆抗体检测和/或测定具有至少两个单独的抗体结合位点或抗原决定簇(即多价抗原)的抗原的方法。 特别地,该方法利用蛋白A与载体来固定第一单克隆抗体,其又可以结合抗原上的一个抗原决定簇。 提供具有标记的第二抗体溶液并与抗原上的第二抗原决定簇结合。 描述了用于实施该方法的测试试剂盒。 描述了新型抗PGH合成酶和抗PGI2合酶抗体以及产生这种抗体的杂交瘤细胞。

    Method of using solid-layered bleach compositions
    83.
    发明授权
    Method of using solid-layered bleach compositions 有权
    使用固体层状漂白剂组合物的方法

    公开(公告)号:US08475678B2

    公开(公告)日:2013-07-02

    申请号:US13610261

    申请日:2012-09-11

    摘要: The present invention provides a method of using a solid-layered composition having at least two parts. The first past comprises a) calcium hypochlorite, magnesium hypochlorite and mixtures thereof, b) a builder, c) a water-soluble polymer, d) an acid, and e) wherein the first part does not contain sodium hypochlorite, lithium hypochlorite, potassium hypochlorite and mixtures thereof. The second part comprises a) a surfactant, b) a builder, c) an acid, and d) wherein the second part does not contain any oxidant.

    摘要翻译: 本发明提供使用具有至少两部分的固体层状组合物的方法。 第一个过去包括a)次氯酸钙,次氯酸镁及其混合物,b)助洗剂,c)水溶性聚合物,d)酸,e)其中第一部分不含次氯酸钠,次氯酸锂,钾 次氯酸盐及其混合物。 第二部分包括a)表面活性剂,b)助洗剂,c)酸,和d)其中第二部分不含任何氧化剂。

    METHODS OF PROVIDING UNIFORM DELIVERY OF A FUNCTIONAL AGENT FROM A SHAPED COMPOSITION
    84.
    发明申请
    METHODS OF PROVIDING UNIFORM DELIVERY OF A FUNCTIONAL AGENT FROM A SHAPED COMPOSITION 有权
    从成型组合物提供功能性物质的均匀提供方法

    公开(公告)号:US20130075346A1

    公开(公告)日:2013-03-28

    申请号:US13427731

    申请日:2012-03-22

    IPC分类号: C02F1/50

    摘要: Methods for introducing a substantially uniform concentration of a functional agent into a flowing stream of water using a shaped composition. The composition may be shaped and sized to be inserted into a device configured to be attached over the end of a faucet. The shaped composition comprises a dissolvable region including a functional agent (e.g., an anti-microbial sanitizing agent). A non-dissolvable region disposed adjacent to the dissolvable region may optionally be provided. The substantially non-dissolvable region remains substantially intact as the dissolving region is progressively dissolved, introducing the functional agent into a flowing stream of water.

    摘要翻译: 使用成形组合物将功能剂基本均匀的浓度引入流动的水流中的方法。 组合物的形状和尺寸可被插入配置成连接在水龙头末端上的装置中。 成型组合物包含包含官能剂(例如抗微生物消毒剂)的可溶性区域。 可以可选地提供邻近可溶区域设置的不溶解区域。 当溶解区逐渐溶解时,基本上不可溶的区域保持基本上完整,将功能剂引入流动的水流中。

    Self-testing sensor
    87.
    发明授权
    Self-testing sensor 有权
    自检传感器

    公开(公告)号:US08258780B2

    公开(公告)日:2012-09-04

    申请号:US12207573

    申请日:2008-09-10

    申请人: William L. Smith

    发明人: William L. Smith

    IPC分类号: G01B7/14 G01B7/30

    CPC分类号: G01P21/02 G01P3/487 G01P3/488

    摘要: Systems and methods for performing a self-test on a sensing device are described in the present disclosure. One implementation, among others, includes a method of performing a self test. In this implementation, the method includes supplying a periodic magnetic field upon a sensing element that is configured to sense a parameter of an object. The method further includes receiving an output from the sensing element indicating the operability of the sensing element. It should be noted that the output is received independently of the parameter of the object.

    摘要翻译: 在本公开中描述了用于在感测装置上执行自检的系统和方法。 一个实施方式包括执行自检的方法。 在该实施方案中,该方法包括在被配置为感测对象的参数的感测元件上提供周期性磁场。 该方法还包括从感测元件接收指示感测元件的可操作性的输出。 应该注意,独立于对象的参数来接收输出。

    Method of treating a substrate with stable bleaches with coloring agents
    89.
    发明授权
    Method of treating a substrate with stable bleaches with coloring agents 有权
    用着色剂处理具有稳定漂白剂的底物的方法

    公开(公告)号:US08148312B2

    公开(公告)日:2012-04-03

    申请号:US13237817

    申请日:2011-09-20

    IPC分类号: C11D3/02 C11D3/37

    摘要: The invention provides an aqueous bleaching solution for substrate treatment comprising a source of oxidant and a suspended polymer matrix having a plurality of optically functional particles associated with one or more copolymers present in the polymer matrix. The plurality of optically functional particles are associated with the copolymer during polymerization of at least one hydrophobic and at least one hydrophilic monomer so as to form a polymer matrix useful to impart an aqueous bleaching solution with optically functional properties providing a benefit to the solutions during storage, use and application to substrates for treatment. In accordance with various embodiments of the invention, the suspended polymer matrix forms a substantially stable dispersion of the optically functional particles in the aqueous bleaching solution, and provides compositions, methods and kits for employing aqueous bleaching solutions having optically functional properties that are maintained over substantially long storage times.

    摘要翻译: 本发明提供了用于底物处理的水性漂白溶液,其包括氧化剂源和悬浮聚合物基质,其具有与存在于聚合物基质中的一种或多种共聚物相关联的多个光学功能性颗粒。 在至少一种疏水性和至少一种亲水性单体的聚合过程中,多种光学功能性颗粒与共聚物相关联,以便形成聚合物基质,其可用于赋予具有光学功能性质的水性漂白溶液以提供储存期间的溶液的益处 ,使用和应用于底物进行治疗。 根据本发明的各种实施方案,悬浮聚合物基质形成水性漂白溶液中的光学功能性颗粒的基本上稳定的分散体,并且提供了使用具有光学功能特性的水性漂白溶液的组合物,方法和试剂盒, 长存储时间。

    POLYELECTROLYTE COMPLEXES
    90.
    发明申请
    POLYELECTROLYTE COMPLEXES 有权
    聚电解质复合物

    公开(公告)号:US20110236450A1

    公开(公告)日:2011-09-29

    申请号:US13046385

    申请日:2011-03-11

    摘要: The present invention relates to aqueous compositions of associative polyelectrolyte complexes (PECs), optionally containing surfactants, biocidal agents and/or oxidants, which can provide a cleaning benefit and surface protection to treated articles including reduced soiling tendency, reduced cleaning effort and improved soil repellancy, as well as providing bacteriostatic properties to treated surfaces that thereby gain resistance to water, environmental exposure and microbial challenge. Treatment means and compositions are provided that employ associative polyelectrolyte complexes formed by combining a water soluble cationic first polyelectrolyte with a water soluble second polyelectrolyte bearing groups of opposite charge to the first polyelectrolyte under suitable mixing conditions and at least one oxidant selected from the group: alkaline metal salts and/or alkaline earth metal salts of hypochlorous acid, hypochlorous acid, solubilized chlorine, any source of free chlorine, acidic sodium chlorite, active chlorine generating,compound and any combinations or mixtures thereof. Also provided are means to form stable associative polyelectrolyte complexes with at least one oxidant in aqueous solutions having R values from about 0.10 to 20.

    摘要翻译: 本发明涉及可选地含有表面活性剂,杀生物剂和/或氧化剂的缔合聚电解质复合物(PEC)的含水组合物,其可以为处理物品提供清洁效果和表面保护,包括减少污染趋势,降低清洁力和改善防污性 ,以及为处理的表面提供抑菌性能,从而获得对水的耐受性,环境暴露和微生物挑战。 提供了处理装置和组合物,其使用通过在适合的混合条件下将水溶性阳离子第一聚电解质与带有相反电荷的水溶性第二聚电解质带入基团的第一聚电解质组合形成的缔合聚电解质复合物和至少一种选自以下的氧化剂:碱 次氯酸,次氯酸,溶解氯,任何游离氯源,酸性亚氯酸钠,生成活性氯的化合物及其任何组合或混合物的金属盐和/或碱土金属盐。 还提供了在水溶液中形成具有约0.10至20的R值的至少一种氧化剂的稳定的缔合聚电解质络合物的方法。