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公开(公告)号:USD761951S1
公开(公告)日:2016-07-19
申请号:US29455733
申请日:2013-05-23
申请人: OPTINOSE AS
设计人: Per Gisle Djupesland
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公开(公告)号:US20160074603A1
公开(公告)日:2016-03-17
申请号:US14694300
申请日:2015-04-23
CPC分类号: A61M15/0098 , A61M15/0021 , A61M15/0023 , A61M15/0028 , A61M15/0035 , A61M15/0041 , A61M15/08 , A61M2202/04 , A61M2202/064 , A61M2205/073 , A61M2206/16
摘要: A delivery device for and method of delivering a metered amount of substance, the delivery device comprising: a mouthpiece through which a user in use exhales; an outlet through which substance is in use delivered; a housing fluidly connected to the mouthpiece and the outlet, such that exhalation by the user through the mouthpiece creates an air flow through the housing and from the outlet; and a substance-dispensing unit which is disposed within the housing and operative to dispense a metered amount of substance into an entraining air flow as created through the housing.
摘要翻译: 用于递送计量的物质的递送装置和方法,所述递送装置包括:用户在使用中呼气的吸嘴; 通过物质运送的出口; 流体连接到接口管和出口的壳体,使得使用者通过接口管呼出,产生通过壳体和出口的气流; 以及物质分配单元,其设置在所述壳体内并且用于将计量的物质分配到通过所述壳体产生的夹带空气流中。
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公开(公告)号:US09205209B2
公开(公告)日:2015-12-08
申请号:US13724560
申请日:2012-12-21
申请人: OPTINOSE AS
发明人: Per Gisle Djupesland
CPC分类号: A61M15/0098 , A61M15/0021 , A61M15/009 , A61M15/0091 , A61M15/08 , A61M16/0434 , A61M16/0493 , A61M16/0495 , A61M2016/0021 , A61M2016/0027 , A61M2202/064 , A61M2202/30 , A61M2210/065
摘要: A delivery device for and method of delivering substance, in particular a vaccine, to a mucosal surface within the oral cavity of a subject, the device comprising: a mouthpiece unit to be gripped in the mouth of a subject, wherein the mouthpiece unit is configured such that, on exhalation or attempted exhalation by the subject, a pressure is developed in the oral cavity which is such as to close the oropharyngeal velum of the subject; and an oral outlet unit including at least one outlet from which substance is in use delivered to a mucosal surface within the oral cavity of the subject.
摘要翻译: 用于将物质特别是疫苗递送到受试者的口腔内的粘膜表面的递送装置和方法,所述装置包括:待夹持在受试者口腔中的接口单元,其中所述接口单元被配置 使得在受试者的呼气或尝试呼气时,在口腔中产生压力以使得关闭受试者的口咽膜; 以及包括至少一个出口的口腔出口单元,所述至少一个出口被用于将物质运送到受试者口腔内的粘膜表面。
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公开(公告)号:US20150165139A1
公开(公告)日:2015-06-18
申请号:US14635561
申请日:2015-03-02
CPC分类号: A61M15/0098 , A61K9/0043 , A61K38/1796 , A61K38/2228 , A61K38/28 , A61M15/0091 , A61M15/08 , A61M2202/064 , A61M2210/0618 , A61M2210/0625
摘要: Intranasal administration of proteins, such as insulin and insulin analogues, in particular immunogenic proteins to the upper posterior region of a nasal cavity of a subject, and in particular the olfactory bulb region.
摘要翻译: 蛋白质如胰岛素和胰岛素类似物,特别是免疫原性蛋白质鼻腔给予受试者鼻腔上后部区域,特别是嗅球区域。
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公开(公告)号:US20150013670A1
公开(公告)日:2015-01-15
申请号:US14380827
申请日:2013-02-25
申请人: OPTINOSE AS
发明人: Per Gisle Djupesland , Michael Leclerc , Rany A. Mahmoud , Shane Siwinski , Joseph Gordon , Justin Fisk
CPC分类号: A61M15/08 , A61M15/0018 , A61M15/002 , A61M15/0021 , A61M15/009 , A61M15/0098 , A61M2210/0618
摘要: A nasal delivery device for and method of delivering substance to a nasal airway of a subject, the delivery device comprising: a nosepiece (117) for fitting to a nasal cavity of a subject; a mouthpiece (119) into which the subject in use exhales; a delivery unit, which comprises an actuation part which is manually displaceable to actuate the delivery unit to deliver substance from the nosepiece; and a valve assembly (127) which is fluidly connected to the nosepiece and the mouthpiece, wherein the valve assembly comprises a body element (128) and a valve element (131) which is movably disposed to the body element between closed and open configurations by manual displacement of the actuation part of the delivery unit to provide for an air flow through the nosepiece simultaneously with delivery of substance.
摘要翻译: 一种用于将物质输送到受试者的鼻气道的鼻输送装置和方法,所述输送装置包括:鼻梁(117),用于装配到受试者的鼻腔; 使用者呼气的受试者(119); 输送单元,其包括可手动地移动以致动输送单元以从物镜输送物质的致动部分; 以及阀组件(127),其流体地连接到所述喷嘴和所述接口管,其中所述阀组件包括主体元件(128)和阀元件(131),所述主体元件(128)和阀元件(131)通过 输送单元的致动部分的手动位移以提供与物质输送同时通过喷嘴的气流。
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公开(公告)号:US20150007811A1
公开(公告)日:2015-01-08
申请号:US14171554
申请日:2014-02-03
申请人: OptiNose AS
发明人: Per Gisle Djupesland , Erik Andreassen , Rune Harald Gaarder , Christophe Péricé , Andreas Nilsson
CPC分类号: A61M15/0098 , A61M11/006 , A61M11/06 , A61M15/0008 , A61M15/002 , A61M15/0021 , A61M15/0028 , A61M15/0031 , A61M15/0086 , A61M15/009 , A61M15/0091 , A61M15/08 , A61M2202/04
摘要: A delivery device for delivering a metered amount of substance (L) in response to exhalation by a user, the delivery device comprising: a mouthpiece (5) through which the user in use exhales; an outlet (45) from which substance Is delivered; and a dispensing unit (35) which is operable to dispense a metered amount of substance through the outlet in response to exhalation by the user through the mouthpiece, wherein the dispensing unit comprises a body member (37) which includes a cavity (39) for containing a metered amount of substance, an outlet nozzle (43) which is fluidly connected to the cavity from which substance is in use delivered, and a dispensing (41) member which is movably disposed in the cavity and configured to be driven through the cavity by a driving pressure created by exhalation of the user, such as to cause substance to be delivered from the outlet nozzle.
摘要翻译: 一种用于响应于使用者的呼气而递送计量的物质(L)的输送装置,所述输送装置包括:用口使用者呼气的吸口(5); 物质输送出口(45); 以及分配单元(35),其可操作以响应于使用者通过所述口件的呼出而通过所述出口分配计量的物质,其中所述分配单元包括主体构件(37),所述主体构件(37)包括用于 包含计量的物质,流体连接到物质被使用的空腔的出口喷嘴(43),以及分配(41)构件,其被可移动地设置在空腔中并构造成被驱动通过空腔 通过使用者的呼出而产生的驱动压力,例如使物质从出口喷嘴输送。
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公开(公告)号:US08800555B2
公开(公告)日:2014-08-12
申请号:US10570034
申请日:2004-08-29
申请人: Per Gisle Djupesland
发明人: Per Gisle Djupesland
CPC分类号: A61M15/0098 , A61M11/001 , A61M15/00 , A61M15/0013 , A61M15/002 , A61M15/0021 , A61M15/0028 , A61M15/0031 , A61M15/0083 , A61M15/08 , A61M2202/30 , A61M2205/7518
摘要: A delivery device for and method of delivering a substance, the delivery device having an outlet member through which substance is in use delivered in an entraining gas flow, and a substance supply unit for supplying substance to be entrained by an entraining gas flow as one or both of a vapor or a fine aerosol mist, wherein the substance supply unit has a flow channel which is fluidly connected to the outlet member, and a substance supporting element for supporting substance, at least a surface of which is in use disposed in the flow channel.
摘要翻译: 用于输送物质的输送装置和输送方法,所述输送装置具有通过物质在夹带气体流中被使用的出口构件,以及物质供应单元,用于将由夹带气流夹带的物质作为一个或多个 蒸汽或细气雾剂,其中物质供应单元具有流体连接到出口构件的流动通道和用于支撑物质的物质支撑元件,其至少其表面在其中被设置在流动中 渠道。
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公开(公告)号:US08590530B2
公开(公告)日:2013-11-26
申请号:US13471146
申请日:2012-05-14
IPC分类号: A61M11/00
CPC分类号: A61M15/002 , A61M15/0021 , A61M15/0028 , A61M15/0035 , A61M15/0041 , A61M15/0045 , A61M15/0086 , A61M15/0091 , A61M15/0098 , A61M15/08 , A61M16/1055 , A61M16/1065 , A61M16/1075 , A61M2202/064
摘要: A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a container-receiving unit comprising a container chamber for receiving a substance-containing container which contains substance to be delivered to the nasal cavity of the subject, the container chamber including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the container chamber; a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the container chamber and through which the subject in use exhales, such as to entrain substance from the container and deliver the same through the nosepiece; and moisture-mitigation means for mitigating an effect of moisture in an exhaled breath on the entrainment of substance from the container.
摘要翻译: 一种用于将物质递送到受试者鼻腔的鼻输送装置和方法,所述输送装置包括:容器接收单元,其包括用于接收含物质的容器的容器室,所述容器容纳物容纳要输送到鼻腔的物质 所述物体,所述容器室包括入口和出口; 鼻梁单元,其包括用于装配到被检体的鼻腔并与容器室的出口流体连通的鼻梁; 接口单元,其包括与容器室的入口流体连通的接口,并且被吸入物体通过其吸入,从而将物质夹带在容器中并将其传送通过喷嘴; 以及用于减轻呼出气中的湿气对来自容器的物质夹带的影响的减湿装置。
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公开(公告)号:US08522778B2
公开(公告)日:2013-09-03
申请号:US12757626
申请日:2010-04-09
申请人: Per Gisle Djupesland
发明人: Per Gisle Djupesland
CPC分类号: A61M15/08 , A61B5/085 , A61B5/097 , A61B5/415 , A61B5/4839 , A61M11/001 , A61M11/005 , A61M11/006 , A61M11/007 , A61M11/02 , A61M15/002 , A61M15/0021 , A61M15/0065 , A61M15/009 , A61M15/0091 , A61M15/0098 , A61M2016/0021 , A61M2202/04 , A61M2202/064 , A61M2205/071 , A61M2205/073 , A61M2205/13 , A61M2210/0668 , A61M2230/43
摘要: A nasal delivery device for and a method of delivering a substance to a nasal cavity of a subject, the delivery device including: a nosepiece for fitting to a nostril of a subject; a substance supply unit for supplying a substance for delivery through the nosepiece; and a delivery prevention mechanism for preventing delivery of a substance through the nosepiece until the nosepiece is properly fitted to the nostril of the subject.
摘要翻译: 一种用于将物质递送到受试者鼻腔的鼻输送装置和输送装置,所述输送装置包括:用于装配到受试者的鼻孔的鼻梁; 物质供应单元,用于提供物质以通过喷射器输送; 以及用于防止物质通过喷嘴的输送直到鼻梁适当地装配到被摄体的鼻孔的输送防止机构。
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公开(公告)号:US20130125889A1
公开(公告)日:2013-05-23
申请号:US13473277
申请日:2012-05-16
CPC分类号: A61M15/0098 , A61M11/02 , A61M15/00 , A61M15/0018 , A61M15/0021 , A61M15/0091 , A61M15/08
摘要: A breath-actuated delivery device includes a mouthpiece through which a subject in use exhales, an air channel which is in fluid communication with the mouthpiece, and a flexible diaphragm which is disposed in the air channel. The diaphragm provides for at least a restricted air flow through the air channel until a predeterminable actuation pressure is developed in the mouthpiece, and, on generation of the predeterminable actuation pressure in the mouthpiece, provides for an air flow through the air channel.
摘要翻译: 一种呼吸致动的输送装置包括一个使用者呼气的受试者的口部,与该口部流体连通的空气通道,以及设置在空气通道中的柔性隔膜。 隔膜至少提供通过空气通道的受限制的空气流,直到在接口管中产生可预定的致动压力,并且在接口管中产生可预定的致动压力时,提供通过空气通道的空气流。
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