公开(公告)号：US20080230567A1

公开(公告)日：2008-09-25

申请号：US11817448

申请日：2006-03-03

申请人： Daljit Ohbi

发明人： Daljit Ohbi

IPC分类号： A61J1/00

CPC分类号： C09K3/10 ,  A61M15/009 ,  C09K2200/0617 ,  C09K2200/062 ,  C09K2200/0642

摘要： A seal for a valve for use in a pharmaceutical dispensing device, which seal is formed from a thermoplastic elastomer including a propylene component with isotactic crystallinity.

摘要翻译： 一种用于药物分配装置的阀的密封件，该密封件由包括具有全同立构结晶度的丙烯组分的热塑性弹性体形成。

公开(公告)号：USD571001S1

公开(公告)日：2008-06-10

申请号：US29280021

申请日：2007-05-14

申请人： Richard Warby ,  Simon Ingram ,  Graham Hately ,  William Southby ,  Martin Swain ,  Andrew Wright

设计人： Richard Warby ,  Simon Ingram ,  Graham Hately ,  William Southby ,  Martin Swain ,  Andrew Wright

公开(公告)号：US20050092679A1

公开(公告)日：2005-05-05

申请号：US10694783

申请日：2003-10-29

申请人： Richard Warby

发明人： Richard Warby

IPC分类号： B01D11/02 ,  C08C3/02 ,  C08F6/00 ,  B01D11/00

CPC分类号： C08C3/02 ,  B01D11/0288 ,  C08F6/005

摘要： A method of cleaning or purifying a polymer which is intended for medical or pharmaceutical use, which method comprises contacting the polymer with an extracting solvent comprising or consisting of an aliphatic alcohol, whereby impurities contained in the polymer are substantially extracted.

摘要翻译： 一种清洁或纯化用于医疗或药物用途的聚合物的方法，该方法包括使聚合物与包含或由脂族醇组成的萃取溶剂接触，由此基本上提取聚合物中所含的杂质。

公开(公告)号：US6131777A

公开(公告)日：2000-10-17

申请号：US056088

申请日：1998-04-07

申请人： Richard John Warby

发明人： Richard John Warby

IPC分类号： B65D83/14 ,  B65D83/00

CPC分类号： B65D83/38

摘要： The invention relates to pressurised dispensing apparatus which includes a container for product to be dispensed, and a valve for controlling outflow of product from the container. The valve includes a valve body located within the container. The container has an open ended container body, and a closure fixedly attached to said container body for closing the open end thereof. The closure has an annular sidewall extending around at least an upper end of the container body. First and second seals are provided, wherein the first seal provides a barrier against the ingress of moisture into the container and the second seal provides a barrier against leakage of the product from the container.

摘要翻译： 本发明涉及加压分配装置，其包括用于待分配的产品的容器和用于控制产品从容器流出的阀。 阀包括位于容器内的阀体。 容器具有开口的容器主体，以及固定地连接到所述容器主体上用于封闭其开口端的封闭件。 封闭件具有围绕容器主体的至少上端延伸的环形侧壁。 提供第一和第二密封件，其中第一密封件提供防止湿气进入容器的阻挡物，并且第二密封件提供防止产品从容器泄漏的屏障。

公开(公告)号：US6062212A

公开(公告)日：2000-05-16

申请号：US392978

申请日：1995-04-11

申请人： John Robin Davison ,  Paul Barnes ,  Geoffrey Brace

发明人： John Robin Davison ,  Paul Barnes ,  Geoffrey Brace

IPC分类号： A61M15/00 ,  B01F3/04 ,  B01F15/02 ,  B05B17/06 ,  A61M11/00

CPC分类号： B01F15/0201 ,  A61M11/005 ,  A61M11/007 ,  A61M15/0066 ,  A61M15/0085 ,  B01F15/0254 ,  B01F3/04049 ,  B05B17/0638 ,  B05B17/0676

摘要： A dispensing apparatus which defines an outlet through which a metered dose of liquid from a reservoir is dispersed as an atomized spray. A droplet of liquid is metered onto a perforate membrane which is vibrated by way of a piezoelectric transducer such that atomized droplets are dispensed through the holes formed in the membrane. At each actuation of a delivery device, which provides the metered quantity of liquid, the transducer is actuated so as to vibrate the membrane for a period greater than the dispensing period required for the droplet to be dispensed. The apparatus is particularly suitable for dispensing pharmaceutical preparations.

摘要翻译： PCT No.PCT / GB93 / 02194 Sec。 371日期1995年04月11日 102（e）日期1995年04月11日PCT提交1993年10月25日PCT公布。 第WO94 / 09912号公报 日期1994年5月11日一种限定出口的分配装置，通过该出口将来自储存器的计量剂量的液体作为雾化喷雾分散。 将一滴液体计量到通过压电换能器振动的穿孔膜上，使得雾化液滴通过形成在膜中的孔分配。 在提供计量量的液体的输送装置的每个致动下，换能器被致动以使膜振动大于要分配的液滴所需的分配周期的时间。 该装置特别适用于分配药物制剂。

公开(公告)号：US5664706A

公开(公告)日：1997-09-09

申请号：US383479

申请日：1995-02-02

申请人： Miro Stan Cater

发明人： Miro Stan Cater

IPC分类号： B05B11/00 ,  G01F11/00

CPC分类号： B05B11/3018

摘要： An atomizing pump (FIG. 1) has a piston (3) slidable in a cylinder (5) to expel liquid from a pump chamber (4). A valve member (8) is slidable in a stem (6) of the piston defining a liquid delivery duct (7). A separately formed cylindrical extension (11) of the valve member is movable in and out of sealing contact with the valve member to open and close a liquid inlet port (105) to the chamber (4). The valve member has a core (102) projecting within the cylindrical extension and having a projecting stop formation (103) which co-operates with a stop formation (104) on the cylindrical extension to limit lost motion between the valve member and cylindrical extension. The valve member is biased into an extended position by a spring acting on the stop member projecting from the core so that the spring extends between the core and the cylindrical extension. This arrangement helps maintain alignment between the pump components and resists buckling of the spring. A bottom end of the cylindrical extension makes sliding contact with an internal wall of a tubular extension (16) of the pump body, continuous sliding contact being maintained to prevent clogging when dispensing water based products.

摘要翻译： 雾化泵（图1）具有可在气缸（5）中滑动以从泵室（4）排出液体的活塞（3）。 阀构件（8）可在限定液体输送管道（7）的活塞的杆（6）内滑动。 阀构件的单独形成的圆柱形延伸部（11）能够与阀构件的密封接触移动，以便打开和关闭到腔室（4）的液体入口（105）。 阀构件具有在圆柱形延伸部内突出的芯部（102），并且具有与圆柱形延伸部上的止动结构（104）配合的突出止挡结构（103），以限制阀构件和圆柱形延伸部之间的运动。 阀构件通过作用在从芯突出的止挡构件上的弹簧偏压到延伸位置，使得弹簧在芯和圆柱形延伸部之间延伸。 这种布置有助于保持泵部件之间的对准并抵抗弹簧的弯曲。 圆柱形延伸部的底端与泵体的管状延伸部（16）的内壁滑动接触，保持连续的滑动接触，以防止在分配水基产品时堵塞。

公开(公告)号：US5547131A

公开(公告)日：1996-08-20

申请号：US253581

申请日：1994-06-03

申请人： Geoffrey Brace

发明人： Geoffrey Brace

IPC分类号： A61M15/00 ,  A61M15/08 ,  B05B11/00 ,  B05B11/02 ,  A61M5/315

CPC分类号： B05B11/0064 ,  A61M11/007 ,  A61M15/0025 ,  A61M15/0065 ,  B05B11/0008 ,  B05B11/007 ,  B05B11/02 ,  B05B11/3091 ,  A61M15/08

摘要： A dispensing device which includes a container for liquid to be dispensed, an outlet nozzle including a device to break-up a flow of liquid under pressure into a spray, a piston for forcing liquid out of the container under pressure and through the nozzle, and a drive device for moving the piston a predetermined distance to dispense a predetermined quantity of liquid from the container. The drive device includes a dose selector for selecting the predetermined amount of liquid and a plunger for moving the piston, movement of the dose selector determining subsequent movement of the plunger. The device is particularly suited to nasal administration of liquid.

摘要翻译： 一种分配装置，其包括用于待分配液体的容器，包括用于在压力下将液体流分解成喷雾器的装置的出口喷嘴，用于在压力下迫使液体排出容器并通过喷嘴的活塞，以及 用于使活塞移动预定距离的驱动装置，以从容器中分配预定量的液体。 驱动装置包括用于选择预定量的液体的剂量选择器和用于移动活塞的柱塞，剂量选择器的运动确定柱塞的后续移动。 该装置特别适用于鼻腔给药液体。

公开(公告)号：US5335830A

公开(公告)日：1994-08-09

申请号：US9964

申请日：1993-01-27

申请人： Miro S. Cater

发明人： Miro S. Cater

IPC分类号： B05B11/00

CPC分类号： B05B11/306 ,  B05B11/3023 ,  B05B11/3074

摘要： Upper and lower hollow cylinders communicate with each other. The diameter of the upper cylinder is larger than that of the lower cylinder. The lower cylinder has an opening through which fluid to be dispensed can be introduced. A piston has an upper vertical hollow cylindrical section open at opposite ends with a first extension in peripheral sealing engagement with the inner surface of the upper cylinder and a lower extension in peripheral sealing engagement with the inner surface of the lower cylinder. An aperture is located in the second extension between its ends. A vertical stem is slidable within and extends through the upper section of the piston. The stem has an enlargement spaced below its upper end. A vertical discharge conduit is coaxial with the piston and stem. An actuator is disposed above the upper cylinder, being secured to the upper end of the stem and having a horizontal discharge channel which communicates with the discharge conduit. The actuator slidably receives the upper end of the upper section of the piston in a region defining a gap. The stem is biased by a spring to close the discharge conduit and to position the enlargement above the aperture when the dispenser is in rest position. The spring is disposed outside the cylinders to exert an upwardly directed biasing force against the actuator and against the upper end of the stem. The piston and actuator can be interconnected in such manner that the dispenser can be placed in locked down position without actuation. This interconnection can be used regardless of the placement of the spring outside or inside the cylinders.

摘要翻译： 上下空心圆筒相互连通。 上部气缸的直径大于下部气缸的直径。 下部气缸具有可以引入待分配流体的开口。 活塞具有在相对端部开口的上部垂直中空圆柱形部分，其具有与上部圆筒的内表面周向密封接合的第一延伸部和与下部圆柱体的内表面周向密封接合的下部延伸部。 孔位于其端部之间的第二延伸部中。 垂直杆可以在活塞的上部部分内滑动并延伸穿过活塞的上部。 茎具有在其上端下方间隔的放大。 垂直排放管道与活塞和阀杆同轴。 致动器设置在上筒的上方，固定在杆的上端，并且具有与排出管道连通的水平排放通道。 致动器在限定间隙的区域中可滑动地容纳活塞的上部的上端。 当分配器处于静止位置时，杆被弹簧偏压以关闭排放导管并将放大部分放置在孔的上方。 弹簧设置在气缸外部，以向致动器施加向上定向的偏压力并抵靠杆的上端。 活塞和致动器可以以这样的方式互连，使得分配器可以被置于锁定位置而不致动。 可以使用这种互连，而不管弹簧在气缸外部或内部的位置如何。

公开(公告)号：US5037013A

公开(公告)日：1991-08-06

申请号：US430341

申请日：1989-11-02

申请人： David J. Howlett

发明人： David J. Howlett

IPC分类号： B65D83/44 ,  B05B9/04 ,  B65D83/14

CPC分类号： B65D83/54

摘要： Dispensing apparatus (1) for dispensing a liquid product (24) from a pressurized dispensing container (21) comprises a collapsible chamber metering valve (2) in which an elastomeric sleeve (4) overlays an external surface (53) of the valve body (6) to define a metering chamber (7) therebetween and is collapsible on actuation of the valve into substantially conformal contact with the external surface such that a volume of liquid is dispensed which is equal to the volume of liquid displaced from the metering chamber. The valve is nestably received within a cup (3) with seal means (15) operable between the mouth of the cup and an outer end of the valve such that a closed collecting chamber (11) is defined between the valve and the cup. Means (25) are provided to communicate in use between the collecting chamber and that part of the container in which a liquid product is contained when the container is held in a predetermined orientation for operation of the valve. The apparatus allows accurate doses of liquids to be dispensed using compressed gas propellant such as nitrogen.

公开(公告)号：US4969578A

公开(公告)日：1990-11-13

申请号：US348361

申请日：1989-05-08

申请人： Terence W. Gander ,  Jeremy K. McCullagh

发明人： Terence W. Gander ,  Jeremy K. McCullagh

IPC分类号： A61M15/00

CPC分类号： A61M15/009

摘要： A dispensing apparatus for nasal administration of an aerosol product is provided with a housing for a pressurized dispensing container with a pivoted cover which in its closed position encloses an outlet duct of the housing. The container is received in a chamber of the housing which is sealed by a bellows portion. An openable closure provides access to the chamber for insertion and removal of the container. The apparatus seals the chamber against ingress of foreign matter between use and encloses the outlet duct to prevent soiling.