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    APPARATUS AND METHOD FOR RAPID MONITORING OF PATHOGENS IN WATER
    2.
    发明申请
    APPARATUS AND METHOD FOR RAPID MONITORING OF PATHOGENS IN WATER 有权

    公开(公告)号：US20230126580A1

    公开(公告)日：2023-04-27

    申请号：US17801677

    申请日：2021-08-18

    申请人： CRANFIELD UNIVERSITY

    发明人： Zhugen YANG

    IPC分类号： C12Q1/689 ,  B01L3/00 ,  C12Q1/6806

    摘要： A method of detecting a pathogen in a water sample. The method includes extracting DNA of the pathogen from a DNA solution derived from a water sample, eluting the DNA through a paper-based microfluidic device having flow channels and then performing LAMP reactions within a set of reaction chambers to obtain LAMP products that may be detected via an amplicon detection test.

    Detection of X-ray scattering
    4.
    发明授权
    Detection of X-ray scattering 有权
    X射线散射检测

    公开(公告)号：US08462913B2

    公开(公告)日：2013-06-11

    申请号：US12602760

    申请日：2008-06-02

    申请人： Paul Evans ,  Keith Rogers

    发明人： Paul Evans ,  Keith Rogers

    IPC分类号： G01N23/207

    CPC分类号： G21K1/02 ,  G21K1/025

    摘要： A radiation detecting apparatus includes a collimator and a detector, the collimator having a material for blocking radiation and a region that is a sector of an annulus or multiple regions in a configuration in the shape of a sector of an annulus for allowing transmission of the radiation. The detector is spaced a distance from the collimator such that when a radiation source and sample crystal material are positioned at suitable positions, the radiation is collimated by the collimator and contacts the sample a predetermined distance from the detector at multiple of locations corresponding to the region or regions of the collimator. The Bragg diffracted radiation from the crystal material at two or more and preferably all of the locations overlap at the detector.

    摘要翻译： 辐射检测装置包括准直器和检测器，准直器具有用于阻挡辐射的材料，以及作为环形扇形形状的环形或多个区域的区域的区域，用于允许放射线的传播 。 检测器与准直器隔开一段距离，使得当辐射源和样品晶体材料位于合适的位置时，辐射被准直器准直并且在对应于该区域的多个位置处与检测器接触预定距离的检测器 或准直仪的区域。 在两个或更多且优选地所有位置处的晶体材料的布拉格衍射辐射在检测器处重叠。

    SENSOR
    7.
    发明申请
    SENSOR 审中-公开
    传感器

    公开(公告)号：US20100173421A1

    公开(公告)日：2010-07-08

    申请号：US12529579

    申请日：2008-02-29

    申请人： Sergey Anatoliyovich Piletsky ,  Yves Frederic Henry ,  Khalku Karim ,  Peter Georg Laitenberger

    发明人： Sergey Anatoliyovich Piletsky ,  Yves Frederic Henry ,  Khalku Karim ,  Peter Georg Laitenberger

    IPC分类号： G01N33/50

    CPC分类号： G01N33/54373 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/1486 ,  A61B5/15003 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/4821 ,  G01N27/404 ,  G01N2600/00 ,  Y10T436/203332

    摘要： This invention relates to a sensor and in particular to a sensor for the detection of biologically important species. Specifically, the invention provides a method for detecting an analyte in the presence of at least one interferent in a sample. The method comprises the steps of providing a sensor having a transducer and a receptor layer in communication with the transducer, in which the receptor layer comprises a material for absorbing the analyte; exposing the receptor layer to the sample; treating the receptor layer to remove selectively the at least one interferent; and measuring the signal from the transducer. The treatment step is performed by applying a change in potential, a change in pH or a change in temperature to the receptor layer, by washing the receptor layer, by irradiating the receptor layer, or a combination thereof.

    摘要翻译： 本发明涉及一种传感器，特别涉及用于检测生物重要物种的传感器。 具体地，本发明提供了一种在样品中存在至少一种干扰物的情况下检测分析物的方法。 该方法包括以下步骤：提供具有换能器和与换能器连通的受体层的传感器，其中接收层包括用于吸收分析物的材料; 将受体层暴露于样品; 处理所述受体层以选择性地除去所述至少一种干扰物; 并测量传感器的信号。 处理步骤是通过对受体层进行洗涤，照射受体层或其组合来施加电位变化，pH变化或温度变化对受体层进行的。

    POLYMERIC BINDING MATERIALS
    8.
    发明申请
    POLYMERIC BINDING MATERIALS 审中-公开
    聚合物结合材料

    公开(公告)号：US20090082480A1

    公开(公告)日：2009-03-26

    申请号：US11916948

    申请日：2006-06-06

    申请人： Sergey Anatoliyovich Piletsky ,  Olena Volodimirivna Piletska ,  Anthony Peter Francis Turner ,  Igor Dubey ,  Larysa Dubey

    发明人： Sergey Anatoliyovich Piletsky ,  Olena Volodimirivna Piletska ,  Anthony Peter Francis Turner ,  Igor Dubey ,  Larysa Dubey

    IPC分类号： C08L33/08 ,  C08F8/12

    CPC分类号： C08F8/12 ,  C08F2810/20 ,  C08F2810/50 ,  C08F212/36 ,  C08F2222/102 ,  C08F8/44

    摘要： A monomer having a pair of hydroxy groups held in a fixed relationship (e.g. a dihydroxybenzene) is diesterified with a compound having a polymerisable group, e.g. to form a diacrylate. After polymerisation with a crosslinker, the polymer is hydrolysed. The dihydroxy-monomer is removed, leaving a polymer with pair of carboxyl groups held in spatial relationships determined by the dihydroxy monomer. Thus a range of subtly different polymers can be prepared by using different dihydroxy-monomer templates. The polymers are desirably swellable. They can be used as selective binding materials, e.g. in chromatography or analysis.

    摘要翻译： 具有固定关系的一对羟基（例如二羟基苯）的单体用具有可聚合基团的化合物， 以形成二丙烯酸酯。 用交联剂聚合后，聚合物被水解。 除去二羟基单体，留下具有由二羟基单体确定的空间关系的一对羧基的聚合物。 因此，可以通过使用不同的二羟基单体模板制备一系列微妙不同的聚合物。 聚合物希望是可溶胀的。 它们可以用作选择性结合材料，例如 在色谱或分析中。

    FLUID SENSING SYSTEMS AND METHODS
    10.
    发明申请
    FLUID SENSING SYSTEMS AND METHODS 有权

    公开(公告)号：US20210349068A1

    公开(公告)日：2021-11-11

    申请号：US17274270

    申请日：2019-09-03

    申请人： Cranfield University

    发明人： James Andrew Bremner ,  Thomas Kissinger ,  Elizabeth Jane Hodgkinson ,  Ralph Peter Tatam

    IPC分类号： G01N33/00 ,  G01N21/45 ,  G01N21/39 ,  G01D5/353

    摘要： An interferometric fluid sensing system is provided. The system comprises: a laser; a plurality of first fibre portions arranged to receive laser light from the laser, wherein each of the first fibre portions comprises a void and an opening to allow fluid from the environment around the corresponding first fibre portion to enter the void, wherein the first fibre portions are configured such that the laser light received by each first fibre portion passes through the corresponding void; a second fibre portion configured to provide a reference arm for the interferometric fluid sensing system; and a detector arranged to receive light from the first and second fibre portions, wherein the system is configured such that the laser light that passes through the void of each first fibre portion is caused to interfere with the light passing through the second fibre portion at or before reaching the detector, wherein each of the first fibre portions is arranged such that that light passing through the void of each first fibre portion travels from the laser to the detector over a different path length from the light passing through the voids of the other first fibre portions, wherein the system is configured such that the wavelength of light provided by the laser varies with time according to a modulated function, the modulated function comprising a first function, which varies through a range of wavelengths, modulated by a second, cyclical carrier function. An interferometric fluid detection method is also provided.