Opto-fluidic nanoparticle detection apparatus
    1.
    发明授权
    Opto-fluidic nanoparticle detection apparatus 有权
    光流体纳米粒子检测装置

    公开(公告)号:US08537356B2

    公开(公告)日:2013-09-17

    申请号:US12920262

    申请日:2009-03-02

    IPC分类号: G01N21/00

    摘要: Provided herein are new methods and apparatus for quantitative measurement and analysis of particles, including new apparatus systems to process and detect nanoparticles in suspension. By focusing a laser beam at the center of a reservoir, nanoparticles are concentrated by optical energy, and fluorescent intensity at the focal point of the laser is measured to quantify particle concentration in the reservoir. The techniques may be applied to the analysis of suspensions of nanoparticles, including natural particles (e.g., microorganisms including whole viruses, bacteria, animal cells, and proteins) and synthetic particles (e.g., colloidal latexes, paints, pigments, and metallic or semiconductor nanoparticles) for medical and industrial applications, among others.

    摘要翻译: 本文提供了用于定量测量和分析颗粒的新方法和装置,包括用于处理和检测悬浮液中的纳米颗粒的新装置系统。 通过将激光束聚焦在储存器的中心,纳米颗粒被光能集中,并且测量激光焦点处的荧光强度以量化储层中的颗粒浓度。 这些技术可以应用于纳米颗粒悬浮液的分析,包括天然颗粒(例如,包括全病毒,细菌,动物细胞和蛋白质的微生物)和合成颗粒(例如胶体胶乳,油漆,颜料和金属或半导体纳米颗粒 )用于医疗和工业应用等。

    Methods for decontamination of powders
    2.
    发明授权
    Methods for decontamination of powders 有权
    粉末去污方法

    公开(公告)号:US08440584B1

    公开(公告)日:2013-05-14

    申请号:US13334829

    申请日:2011-12-22

    IPC分类号: C04B41/00

    摘要: Provided herein are methods and apparatus to remove unwanted elements in commercial powders, and particularly in commercial powders that include one or more of a crystalline ceramic oxide. The methods involve treating powders in reduced pressure atmosphere, such as a vacuum, with or without heating, for a period of time sufficient to remove impurities. Impurities and contaminants, including anionic species, are removed from the powders without any undesirable changes in the physical characteristics of the starting material, such as particle size and particle size distribution, surface area, and volume, for example. The resulting purified powder starting material can be consolidated without the need for any sintering aids such as LiF to produce nearly colorless, extremely transparent polycrystalline articles that approach identical properties and performance of single crystal spinels.

    摘要翻译: 本文提供了去除商业粉末中的不需要的元素的方法和装置,特别是在包括结晶陶瓷氧化物中的一种或多种的商业粉末中。 所述方法包括在减压或低温气氛中处理粉末,例如真空,加热或不加热,持续一段足以除去杂质的时间。 杂质和污染物(包括阴离子物质)从粉末中除去,例如,起始材料的物理特性如颗粒尺寸和粒度分布,表面积和体积没有任何不期望的变化。 所得到的纯化粉末起始材料可以被固结,而不需要诸如LiF的任何烧结助剂,以产生接近单晶尖晶石相同特性和性能的几乎无色,极透明的多晶制品。

    Miniature oxygen concentrators and methods
    3.
    发明授权
    Miniature oxygen concentrators and methods 有权
    微型氧气浓缩器和方法

    公开(公告)号:US08226745B2

    公开(公告)日:2012-07-24

    申请号:US12769283

    申请日:2010-04-28

    IPC分类号: B01D53/047

    摘要: Provided herein are new compact and miniature oxygen concentrator apparatus, as well as methods incorporating use of the apparatus. The apparatus and methods utilize selected cycle times, adsorbent specifications and novel conditions to produce a fast Pressure Swing Adsorption (“PSA”) system. The oxygen concentrator apparatus and methods herein have significant utility in the fields of biotechnology, engineering, and medicine. A particularly advantageous use of this invention is as a “snap on” portable oxygen concentrator, where piped compressed air is already available such as in civil and military hospitals, ambulances, air craft cabins, mobile fish tanks, etc. Those embodiments eliminate the need for dedicated moving machinery (blower, compressor, vacuum pump) normally associated with a conventional PSA oxygen concentrator.

    摘要翻译: 本文提供了新的紧凑型和微型氧气浓缩装置,以及结合使用该装置的方法。 该设备和方法利用选择的循环时间,吸附剂规格和新条件来产生快速压力摆动吸附(“PSA”)系统。 本发明的氧气浓缩装置和方法在生物技术,工程,医药领域具有重要的实用价值。 本发明的特别有利的用途是作为“快速”便携式氧气浓缩器,其中管道压缩空气已经可用,例如在民用和军用医院,救护车,飞机舱,移动鱼缸等中。这些实施例消除了需要 通常与常规PSA氧浓缩器相关联的专用移动机械(鼓风机,压缩机,真空泵)。

    Nano/macroporous bone tissue scaffolds for regenerative medicine
    4.
    发明授权
    Nano/macroporous bone tissue scaffolds for regenerative medicine 有权
    用于再生医学的纳米/大孔骨组织支架

    公开(公告)号:US08277829B2

    公开(公告)日:2012-10-02

    申请号:US12377699

    申请日:2007-08-30

    CPC分类号: A61L27/56 A61L27/52

    摘要: A biocompatible inorganic porous material having a three-dimensional coexistent network of interconnected macro-pores and nanopores produced by the steps of mixing an organic water-soluble polymer (e.g., polyethylene oxide or a block copolymer of ethylene oxide and propylene oxide), an alkoxysilane, and an inorganic water-soluble calcium salt in an aqueous acid solution, such that a sol-gel process of hydrolysis and polycondensation is initiated and thereby producing a gel; drying the gel to remove solvent by evaporation; and heating the gel to remove the polymer by thermal decomposition, thereby forming an inorganic porous material, which may be suitable for use as a bone tissue scaffold.

    摘要翻译: 具有通过混合有机水溶性聚合物(例如,聚环氧乙烷或环氧乙烷和环氧丙烷的嵌段共聚物),烷氧基硅烷等的相互连接的大孔和纳米孔的三维共存网络的生物相容性无机多孔体 和无水水溶性钙盐,在酸性水溶液中开始水解和缩聚的溶胶 - 凝胶法,从而产生凝胶; 干燥凝胶以通过蒸发除去溶剂; 并加热凝胶以通过热分解除去聚合物,从而形成可适合用作骨组织支架的无机多孔材料。

    Meltable fuel gas generation apparatus and methods
    5.
    发明授权
    Meltable fuel gas generation apparatus and methods 有权
    可燃燃气发生装置及方法

    公开(公告)号:US08268027B2

    公开(公告)日:2012-09-18

    申请号:US12709967

    申请日:2010-02-22

    申请人: Raymond M Gatt

    发明人: Raymond M Gatt

    IPC分类号: C10J3/46

    摘要: Gas generation apparatus and methods are provided, including apparatus and methods for efficient vaporization, and optional burning, of meltable fuels. The apparatus and methods provide controlled generation and combustion of any low melting point dimensionally stable combustible meltable fuel. This is preferably accomplished by first converting the solid or semi solid meltable fuel material into a liquid state, then into vapor, and finally mixing with an air source or other oxidizer before combustion.

    摘要翻译: 提供了气体生成装置和方法,其包括可熔化燃料的有效蒸发和任选燃烧的装置和方法。 该设备和方法提供任何低熔点尺寸稳定的易燃可燃燃料的受控生成和燃烧。 这优选通过首先将固体或半固体可熔融燃料材料转化为液体状态,然后转化为蒸气,最后在燃烧之前与空气源或其它氧化剂混合。

    Active matrix display and method
    7.
    发明授权
    Active matrix display and method 失效
    主动矩阵显示和方法

    公开(公告)号:US08390536B2

    公开(公告)日:2013-03-05

    申请号:US11608881

    申请日:2006-12-11

    IPC分类号: G09G3/16

    摘要: An active matrix display includes at least one data driver circuit comprising a column data line and a parallel column current line; a plurality of pixels connected in series to both the column data line and the parallel column current line comprising at least one pixel that is responsive to the column data line to drive a selected pixel current to the at least one pixel; and a loopback control circuit at the head of the column and external to the plurality of pixels that senses a voltage difference between an input column current in the current line and a voltage of a load drawing on the current line and that adjusts a data programming voltage according to the difference.

    摘要翻译: 有源矩阵显示器包括至少一个包括列数据线和​​并行列电流线的数据驱动器电路; 与列数据线和​​并行列电流线串联连接的多个像素包括响应于列数据线的至少一个像素,以将所选择的像素电流驱动到至少一个像素; 以及在所述列的头部并且在所述多个像素的外部的环回控制电路,其感测当前行中的输入列电流与当前行上的负载绘制电压之间的电压差,并且调节数据编程电压 根据差异

    Nano/macroporous bioactive glasses made by melt-quench methods
    8.
    发明授权
    Nano/macroporous bioactive glasses made by melt-quench methods 有权
    通过熔融淬火方法制备的纳米/大孔生物活性眼镜

    公开(公告)号:US08389018B2

    公开(公告)日:2013-03-05

    申请号:US12526599

    申请日:2008-02-13

    IPC分类号: A01N59/26 A61K33/42

    CPC分类号: A61L27/10 A61L27/56

    摘要: The methods and materials described herein provide novel and simple procedures for the preparation of nano/macroporous glasses, in which the pore structure is characterized by interconnected pores of, e.g. both hundreds of micrometers and several to tens of nanometers in size. Such materials may be used for enhanced bone regeneration, bioscaffolds, drug delivery devices, and filtration media, among other uses. For example, silica-based bone tissue scaffolds are made with a controlled nano/macroporosity, which enhances bone regeneration performance. Also provided herein are new biocompatible CaO—Na2O—P2O5—SiO2 glasses prepared by thermal melt-quench methods that result in spinodal phase separation and crystallization of phases at very different length scales. Selective chemical leaching of these phases causes formation of interconnected multi-modal porosity, with pore sizes ranging from several nanometers to tens of micrometers.

    摘要翻译: 本文所述的方法和材料提供用于制备纳米/大孔玻璃的新颖且简单的方法,其中孔结构的特征在于例如相互连通的孔。 数百微米和几十纳米的尺寸。 除了其它用途之外,这种材料可用于增强骨再生,生物支架,药物递送装置和过滤介质。 例如,二氧化硅基骨组织支架用受控的纳米/大孔隙度制成,这增强了骨再生性能。 本文还提供了通过热熔融淬火方法制备的新的生物相容性CaO-Na 2 O-P 2 O 5 -SiO 2玻璃,其导致在非常不同长度尺度的相旋转相分离和结晶相。 这些相的选择性化学浸出导致互连的多模式孔隙的形成,其孔径范围从几纳米到几十微米。