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1.发明申请公开(公告)号：US20200320741A1
公开(公告)日：2020-10-08
申请号：US16301279
申请日：2017-05-08
发明人： Edward HÆGGSTRÖM , Ivan KASSAMAKOV , Anton NOLVI , Niklas SANDLER , Tapani VIITALA , Johan NYMAN
摘要： An artifact for determining resolution of imaging based on electromagnetic radiation, mechanical waves, or both is presented. The artifact includes a substrate and layers on top of the substrate. The layers include organic material and are stacked on each other in a partially overlapping way so that an edge of a first one of the layers is arranged to intersect with an edge of a second one of the layers. The layers constitute a three-dimensional surface topography where a groove defined by the edges of the first and second ones of the layers is tapering towards a point of intersection between the edges. The resolution is a minimum width of the tapering groove which is revealed by the imaging so that a pre-determined criterion is fulfilled.
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公开(公告)号：US20170261309A1
公开(公告)日：2017-09-14
申请号：US15528679
申请日：2015-10-29
发明人： Edward HÆGGSTROM , Ivan KASSAMAKOV , Anton NOLVI , Tuomo YLITALO , Niklas SANDLER , Tapani VIITALA , Johan NYMAN
IPC分类号： G01B9/02
CPC分类号： G01B9/02072 , G01B9/0209
摘要： A method for calibrating electromagnetic radiation-based three-dimensional imaging includes: obtaining (501) a calibration imaging result at least partly on the basis of electromagnetic waves received from a calibration artifact, forming (502) calibration data on the basis of the calibration imaging result and a known thickness profile of the calibration artifact, and correcting (503), with the aid of the calibration data, an imaging result obtained at least partly on the basis of electromagnetic waves received from a sample to be imaged. The calibration artifact includes layers, for example Langmuir-Blodgett films, having pre-determined thicknesses and stacked on each other so as to achieve the pre-determined thickness profile of the calibration artifact. A three-dimensional imaging system configured to carry out the method.
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公开(公告)号：US10988716B2
公开(公告)日：2021-04-27
申请号：US16072644
申请日：2017-03-21
发明人： Pedro Fardim , Thomas Heinze , Holger Wondraczek , Olga Gabova
IPC分类号： C11D3/42 , A61K8/73 , C08B15/06 , D21H21/30 , A61Q19/00 , C11D3/28 , C11D3/20 , C11D3/34 , D21H17/24 , D21C9/00 , C08B13/00 , D21H19/38
摘要： Provided herein are polysaccharide derivatives substituted (a) at a degree of substitution (DS1) of at least 0.05 by a fluorescent group (FG) having a mono or polycyclic ring system including at least one heteroatom selected from N, O and S and conjugated double bonds, and having an absorption band in the UV region of light and an emission band in the visible region of light, and bonded via a first linker to any one of the native functional groups of the polysaccharide repeating units; and (b) at a degree of substitution (DS2) of at least 0.05 by a charged group (CG) bonded via a second linker to any one of the native functional groups of the polysaccharide repeating units.
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公开(公告)号：US20230011245A1
公开(公告)日：2023-01-12
申请号：US17779822
申请日：2020-11-25
摘要： A method and apparatus of detecting incipient corrosion on surfaces of an object. The method comprising immersing the object into an electrolyte, and detecting by electrochemical techniques the presence of corrosion on the surfaces of the object based on current originating from redox reaction of iron.
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公开(公告)号：US20220289903A1
公开(公告)日：2022-09-15
申请号：US17641285
申请日：2020-09-10
IPC分类号： C08G63/08 , C08G63/688 , A61K31/65 , A61K31/337 , A61K47/59
摘要： The present invention relates to polymers, compositions thereof, and methods of producing polymers in general. Furthermore, the present invention relates to pharmaceutical compositions and uses of said polymers, compositions and pharmaceutical compositions. More particular, the present invention relates to polymers of jasmine lactone, where pendant groups of said polymers can readily be used for attaching functional moieties comprising active agents. Furthermore, the present invention relates to modified jasmine lactones that can readily be used in methods of producing polymers of the present invention. More particular, the invention relates to polymers from renewable monomers, which can be used in applications such as drug delivery and diagnosis, polymer-drug conjugates, medical devices, cosmetic products, polymers with marker unit, polymers usable as flame retardants, tissue engineering, coatings, paints, lubricants and biodegradable plastics.
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公开(公告)号：US20160101108A1
公开(公告)日：2016-04-14
申请号：US14892997
申请日：2014-05-23
IPC分类号： A61K31/525 , A61K33/10 , A61K9/20 , A61K31/375 , A61K31/465 , A61K31/455 , A61K33/08
CPC分类号： A61K31/525 , A23L33/00 , A23L33/15 , A23L33/155 , A23L33/16 , A23P10/10 , A61K9/006 , A61K9/2009 , A61K9/2072 , A61K9/2095 , A61K9/7007 , A61K31/375 , A61K31/455 , A61K31/465 , A61K33/08 , A61K33/10 , A61K2300/00
摘要： The present invention relates to oral dosage forms of vitamin(s) and/or dietary mineral(s) or nicotine produced by printing techniques. The present invention also relates to a method of producing an oral dosage form of vitamin(s) and/or dietary mineral(s) or nicotine by printing technique(s).
摘要翻译： 本发明涉及通过印刷技术生产的维生素和/或膳食矿物或尼古丁的口服剂型。 本发明还涉及一种通过印刷技术生产维生素和/或膳食矿物或尼古丁的口服剂型的方法。
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公开(公告)号：US11953422B2
公开(公告)日：2024-04-09
申请号：US17779822
申请日：2020-11-25
CPC分类号： G01N17/02 , G01N17/006 , G06F2218/12
摘要： A method and apparatus of detecting incipient corrosion on surfaces of an object. The method comprising immersing the object into an electrolyte, and detecting by electrochemical techniques the presence of corrosion on the surfaces of the object based on current originating from redox reaction of iron.
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公开(公告)号：US20190390277A1
公开(公告)日：2019-12-26
申请号：US16469337
申请日：2017-12-14
发明人： Dani FLINKMAN , Ye HONG , Prasannakumar Shriprakash DESHPANDE , Tomas Lassi-Pekka LAURÉN , Sirkku PELTONEN , Valtteri KAASINEN , Peter Hywel JAMES , Eleanor Therese COFFEY
IPC分类号： C12Q1/6883
摘要： The present invention relates to diagnostics of Parkinson's disease (PD), preferably at an early stage, more preferably at the prodromal stage. The invention can be utilized in methods of diagnosing PD, monitoring progression of PD, monitoring response to treatment, or stratifying subjects for clinical studies, for instance. Also provided is a kit for use in said methods.
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公开(公告)号：US20190002801A1
公开(公告)日：2019-01-03
申请号：US16072644
申请日：2017-03-21
发明人： Pedro FARDIM , Thomas HEINZE , Holger WONDRACZEK , Olga GABOVA
摘要： Provided herein are polysaccharide derivatives substituted (a) at a degree of substitution (DS1) of at least 0.05 by a fluorescent group (FG) having a mono or polycyclic ring system including at least one heteroatom selected from N, O and S and conjugated double bonds, and having an absorption band in the UV region of light and an emission band in the visible region of light, and bonded via a first linker to any one of the native functional groups of the polysaccharide repeating units; and (b) at a degree of substitution (DS2) of at least 0.05 by a charged group (CG) bonded via a second linker to any one of the native functional groups of the polysaccharide repeating units.
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10.发明申请An arrangement for facilitating wound healing, a method for measuring wound healing and a wound dressing 审中-公开用于促进伤口愈合的装置，用于测量伤口愈合的方法和伤口敷料公开(公告)号：US20160101282A1
公开(公告)日：2016-04-14
申请号：US14893084
申请日：2014-05-21
发明人： Mikael Bergelin , Jan-Erik Eriksson , Max Johansson , Chunlin Xu , Ann-Sofie Leppänen , Stefan Willför , Simo Köppä , Atte Kekonen , Heimo O. Ylänen , Jari Viik , Jari Hyttinen
CPC分类号： A61N1/205 , A61B5/053 , A61B5/0531 , A61B5/445 , A61B5/4848 , A61F13/0253 , A61N1/0468 , A61N1/0476 , A61N1/0484 , A61N1/0496 , A61N1/36014
摘要： The present invention relates to the field of electrotherapy and measuring by means of electric currents for diagnostic purposes, and more particularly to an electrode arrangement for facilitating wound healing, a method for measuring wound healing and a wound dressing having an electrode arrangement. A wound dressing according to the present invention comprises at least two impedance reference electrodes, a frame like counter-electrode and stimulation electrodes in a form of an array; and a bioadhesive affinity layer surrounding the stimulation electrodes; said wound dressing being suited for applying on top of the wound so that the stimulation electrode array is on the wound area, and that the at least two impedance reference electrodes and the frame like counter-electrode are suited for placing in contact with the healthy skin surrounding the wound area; which electrodes, are suited for applying LIDC type electrical stimulation current to the wound area and for bioimpedance measurement. The wound dressing according to the present invention provide a continuous, non-invasive and objective solution for monitoring chronic wound healing without disturbing the delicate healing process.
摘要翻译： 本发明涉及用于诊断目的的用于电疗和电流测量的领域，更具体地涉及用于促进伤口愈合的电极装置，用于测量伤口愈合的方法和具有电极装置的伤口敷料。 根据本发明的伤口敷料包括至少两个阻抗参考电极，像对电极的框架和阵列形式的刺激电极; 以及围绕刺激电极的生物粘附亲和层; 所述伤口敷料适于施加在伤口的顶部，使得刺激电极阵列在伤口区域上，并且至少两个阻抗参考电极和框架反向电极适于放置与健康皮肤接触 围绕伤口区域; 哪些电极适于将LIDC型电刺激电流施加到伤口区域并用于生物阻抗测量。 根据本发明的伤口敷料提供用于监测慢性伤口愈合的连续的非侵入性和客观的解决方案，而不会干扰微妙的愈合过程。
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