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    Blood component processing systems and methods using fluid-actuated pumping elements that are integrity tested prior to use
    1.
    发明授权
    Blood component processing systems and methods using fluid-actuated pumping elements that are integrity tested prior to use 有权
    使用流体驱动泵送元件的血液成分处理系统和方法在使用前被完整性测试

    公开(公告)号：US07004727B2

    公开(公告)日：2006-02-28

    申请号：US10983014

    申请日：2004-11-05

    申请人： Tiffany Kline ,  Peter Bedard ,  Carson Ingo ,  Christopher Boniquit ,  Robert Scheidt ,  Abinash Nayak

    发明人： Tiffany Kline ,  Peter Bedard ,  Carson Ingo ,  Christopher Boniquit ,  Robert Scheidt ,  Abinash Nayak

    IPC分类号： F04B43/06 ,  A61M1/00

    CPC分类号： A61M1/3693 ,  A61M1/0218 ,  A61M1/3633 ,  A61M1/3652 ,  A61M1/3663 ,  A61M1/3696 ,  A61M2205/128 ,  A61M2205/331 ,  A61M2205/3393 ,  A61M2205/705 ,  A61M2209/084 ,  F04B43/009 ,  F04B43/06

    摘要： Blood component processing systems and methods are coupled to a blood component processing device. The systems and methods include a fluid circuit that comprises at least one fluid pressure actuated pump station, at least one fluid flow path communicating with the pump station, and at least one valve in the fluid flow path. A control module is sized and configured to interact with the fluid circuit. The control module includes an actuator to selectively apply fluid pressure to the pump station in concert with operation of the valve to pump fluid through the fluid flow path in response to a control program. A controller coupled to the control module includes the control program and a fluid circuit integrity test function. The fluid circuit integrity test function commands the control module to selectively apply fluid pressure to the pump station in concert with operation of the valve to introduce a fluid within a region of the fluid circuit and to confine the fluid within the region while applying fluid pressure to the pump chamber. The fluid circuit integrity test function generates an integrity output in response to sensing leakage of fluid from the region.

    摘要翻译： 血液成分处理系统和方法耦合到血液成分处理装置。 该系统和方法包括流体回路，其包括至少一个流体压力致动的泵站，与泵站连通的至少一个流体流动路径和流体流路中的至少一个阀。 控制模块的尺寸和构造与流体回路相互作用。 控制模块包括致动器，以响应于控制程序与阀的操作一起选择性地向泵站施加流体压力以泵送流体通过流体流动路径。 耦合到控制模块的控制器包括控制程序和流体电路完整性测试功能。 流体回路完整性测试功能命令控制模块选择性地将流体压力施加到泵站，与阀的操作一致，以在流体回路的区域内引入流体并且将流体限制在该区域内，同时将流体压力 泵室。 流体回路完整性测试功能响应于感测来自该区域的流体泄漏而产生完整性输出。

    Blood component processing systems and methods using fluid-actuated pumping elements that are integrity tested prior to use
    4.
    发明授权
    Blood component processing systems and methods using fluid-actuated pumping elements that are integrity tested prior to use 有权
    使用流体驱动泵送元件的血液成分处理系统和方法在使用前被完整性测试

    公开(公告)号：US06846161B2

    公开(公告)日：2005-01-25

    申请号：US10280108

    申请日：2002-10-24

    申请人： Tiffany Kline ,  Peter Bedard ,  Carson Ingo ,  Christopher Boniquit ,  Robert Scheidt ,  Abinash Nayak

    发明人： Tiffany Kline ,  Peter Bedard ,  Carson Ingo ,  Christopher Boniquit ,  Robert Scheidt ,  Abinash Nayak

    IPC分类号： A61M1/36 ,  F04B43/00 ,  F04B43/06 ,  F04B49/00 ,  A61M1/00

    CPC分类号： A61M1/3693 ,  A61M1/0218 ,  A61M1/3633 ,  A61M1/3652 ,  A61M1/3663 ,  A61M1/3696 ,  A61M2205/128 ,  A61M2205/331 ,  A61M2205/3393 ,  A61M2205/705 ,  A61M2209/084 ,  F04B43/009 ,  F04B43/06

    摘要： Blood component processing systems and methods are coupled to a blood component processing device. The systems and methods include a fluid circuit that comprises at least one fluid pressure actuated pump station, at least one fluid flow path communicating with the pump station, and at least one valve in the fluid flow path. A control module is sized and configured to interact with the fluid circuit. The control module includes an actuator to selectively apply fluid pressure to the pump station in concert with operation of the valve to pump fluid through the fluid flow path in response to a control program. A controller coupled to the control module includes the control program and a fluid circuit integrity test function. The fluid circuit integrity test function commands the control module to selectively apply fluid pressure to the pump station in concert with operation of the valve to introduce a fluid within a region of the fluid circuit and to confine the fluid within the region while applying fluid pressure to the pump chamber. The fluid circuit integrity test function generates an integrity output in response to sensing leakage of fluid from the region.

    摘要翻译： 血液成分处理系统和方法耦合到血液成分处理装置。 该系统和方法包括流体回路，其包括至少一个流体压力致动的泵站，与泵站连通的至少一个流体流动路径和流体流路中的至少一个阀。 控制模块的尺寸和构造与流体回路相互作用。 控制模块包括致动器，以响应于控制程序与阀的操作一起选择性地向泵站施加流体压力以泵送流体通过流体流动路径。 耦合到控制模块的控制器包括控制程序和流体电路完整性测试功能。 流体回路完整性测试功能命令控制模块选择性地将流体压力施加到泵站，与阀的操作一致，以在流体回路的区域内引入流体并且将流体限制在该区域内，同时将流体压力 泵室。 流体回路完整性测试功能响应于感测来自该区域的流体泄漏而产生完整性输出。

    System and methods for control of pumps employing electrical field sensing
    5.
    发明授权
    System and methods for control of pumps employing electrical field sensing 有权
    用于控制采用电场感测的泵的系统和方法

    公开(公告)号：US06261065B1

    公开(公告)日：2001-07-17

    申请号：US09390491

    申请日：1999-09-03

    申请人： Abinash Nayak ,  James D. Jacobson ,  Tom Westberg ,  William E Brach ,  Richard I Brown

    发明人： Abinash Nayak ,  James D. Jacobson ,  Tom Westberg ,  William E Brach ,  Richard I Brown

    IPC分类号： F04B1924

    CPC分类号： F04B49/12 ,  F04B49/06 ,  F04B2205/09

    摘要： Systems and related methods pump fluid through a pump. The pump comprises a pump chamber, which is responsive to applied pressures to convey fluid. The systems and methods place an electrode in the pump chamber which, in use, is coupled to a current source. The electrode generates an electrical field in the pump chamber that varies according volume of fluid in the pump chamber. The systems and methods register variations in the electrical field as fluid is conveyed through the pump chamber.

    摘要翻译： 系统和相关方法通过泵泵送液体。 泵包括泵室，其响应于施加的压力来输送流体。 所述系统和方法将电极放置在泵室中，所述泵室在使用中与电流源耦合。 电极在泵室中产生电场，该电场随泵室中的流体体积而变化。 当流体通过泵室输送时，系统和方法记录电场中的变化。

    Optical interface detection system for centrifugal blood processing
    6.
    发明授权
    Optical interface detection system for centrifugal blood processing 失效
    用于离心血液处理的光学界面检测系统

    公开(公告)号：US06254784B1

    公开(公告)日：2001-07-03

    申请号：US08961340

    申请日：1997-10-30

    申请人： Abinash Nayak ,  Clint D. Luckinbill ,  John T. Foley ,  Minh D. Tran ,  James R. Bradley ,  Timothy J. Patno

    发明人： Abinash Nayak ,  Clint D. Luckinbill ,  John T. Foley ,  Minh D. Tran ,  James R. Bradley ,  Timothy J. Patno

    IPC分类号： B01D1712

    CPC分类号： B01D17/0217 ,  B04B2013/006 ,  G01N15/042 ,  G01N15/05 ,  G01N2015/045

    摘要： A centrifuge for continuously separating the various constituents of blood or other biological fluids includes a rotating bowl having high-G and low-G walls. An inwardly directed ramped surface on the high-G wall interacts with an interface region between the separated fluid constituents to provide an optically detectable indication of the position of the interface between the high-G and low-G walls. An optical sensor sensing each passage of the ramped surface past a point develops a changing signal indicative of the interface position. Signal processing circuitry responsive to the signal measures such signal parameters as peak amplitude, signal area and signal shape. By so monitoring these signal parameters, a better indication of actual interface position between the high-G and low-G walls can be obtained. This, in turn, results in better control over centrifuge operation and improved separation of the desired fluid components.

    摘要翻译： 用于连续分离血液或其他生物流体的各种成分的离心机包括具有高G和低G壁的旋转碗。 高G壁上的向内倾斜的表面与分离的流体组分之间的界面区域相互作用，以提供高G和低G壁之间界面的位置的可光学检测的指示。 感测倾斜表面的每个通过点的光学传感器产生指示接口位置的变化信号。 响应于信号的信号处理电路测量诸如峰值幅度，信号面积和信号形状的信号参数。 通过监测这些信号参数，可以获得高G和低G壁之间的实际界面位置的更好的指示。 这反过来导致更好地控制离心机操作和改进所需流体组分的分离。