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公开(公告)号：US10124129B2
公开(公告)日：2018-11-13
申请号：US12808686
申请日：2008-12-24
申请人： Stephen T. Dunne , Achim Moser
发明人： Stephen T. Dunne , Achim Moser
摘要： The invention relates to a dispensing device, a storage device and a method for dispensing a medical formulation. Multiple doses of the formulation are stored in a carrier having multiple storage members, each storage member containing a single dose. Each storage member comprises one duct or nozzle for dispensing the respective dose. The dispensing direction of the ducts or nozzles is directed in a lengthwise or indexing direction of the carrier. The storage device of the carrier is a peelable blister strip, wherein the ducts or nozzles can be opened one after the other by peeling the blister strip.
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公开(公告)号：US20120222675A1
公开(公告)日：2012-09-06
申请号：US13469631
申请日：2012-05-11
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M11/001 , A61M11/002 , A61M11/02 , A61M15/0003 , A61M15/002 , A61M15/0031 , A61M15/0033 , A61M15/0045 , A61M15/0048 , A61M15/0051 , A61M2202/064 , A61M2205/073 , A61M2205/8225 , A61M2206/16
摘要： A dispensing device, and a method for dispensing powder in which powder is dispensed through a duct with a flat cross section to de-agglomerate the powder and to generate a spray with fine particle size. A storage chamber for the powder may be closed by a bursting element which is burst by pressurized gas for discharging the powder, the gas pressure reaching or exceeding a peak value before the bursting element bursts so that the powder is dispensed at a lower gas pressure. The powder may be forced through the duct by a gas pressure of less than 300 kPa to de-agglomerate the powder and/or to generate the spray. The storage device can have multiple storage chambers and associated ducts or nozzles, so that each dose of powder can be dispensed through a separate duct or nozzle, the storage chamber and duct or nozzle being formed of a one-piece construction.
摘要翻译： 一种分配装置和分配粉末的方法，其中通过具有平坦横截面的管道分配粉末，以使粉末脱颗粒并产生具有细粒度的喷雾。 用于粉末的储存室可以由爆破元件封闭，该破裂元件通过用于排出粉末的加压气体爆裂，气体压力在爆裂元件爆发之前达到或超过峰值，使得粉末以较低的气体压力被分配。 可以通过小于300kPa的气体压力将粉末强制通过管道，以使粉末脱团解和/或产生喷雾。 存储装置可以具有多个存储室和相关联的管道或喷嘴，使得每一剂量的粉末可以通过单独的管道或喷嘴分配，储存室和管道或喷嘴由单件结构形成。
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3.发明申请Medicaments Magazine, and a Device and Method for Opening it; Multi-Dose Powder Inhaler 有权药品杂志，以及打开它的装置和方法; 多剂量吸入器公开(公告)号：US20090101145A1
公开(公告)日：2009-04-23
申请号：US12296984
申请日：2007-04-13
申请人： Herbert Wachtel , Johannes Geser , Burkhard Metzger , Michael Spallek , Michael Krueger , Herbert Kunze , Achim Moser , Elmar Mock , Antonio Lanci , Andre Klopfenstein
发明人： Herbert Wachtel , Johannes Geser , Burkhard Metzger , Michael Spallek , Michael Krueger , Herbert Kunze , Achim Moser , Elmar Mock , Antonio Lanci , Andre Klopfenstein
CPC分类号： A61M15/0045 , A61M15/0043 , A61M15/0051
摘要： The invention relates to a medicament magazine with a plurality of doses of medicament, wherein the magazine is formed from a single foil strip in which pouches (2) for holding a medicament are formed. The foil strip comprises for transporting the strip openings (4) on at least one side for the engagement of transporting pins. The foil strip has a certain width in the region of the pouches, which is less than the width of the foil in other regions, and the openings are arranged in this broader part of the foil strip. The invention also relates to a method and a device for opening a medicament magazine of this kind, the device preferably being constructed as a segmented wheel.
摘要翻译： 本发明涉及一种具有多个剂量的药物的药物储存器，其中所述杂物盒由单个箔条形成，其中形成用于保持药物的袋（2）。 箔条包括用于在至少一个侧面上传送条形开口（4）用于传送销的接合。 箔条在袋的区域中具有一定的宽度，其小于其它区域中的箔的宽度，并且开口布置在箔条的更宽的部分中。 本发明还涉及一种用于打开这种药物盒的方法和装置，该装置优选构造为分段轮。
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公开(公告)号：US09283335B2
公开(公告)日：2016-03-15
申请号：US11576853
申请日：2005-10-06
CPC分类号： A61M15/0028 , A61M11/001 , A61M11/002 , A61M11/02 , A61M15/0003 , A61M15/002 , A61M15/0031 , A61M15/0033 , A61M15/0045 , A61M15/0048 , A61M15/0051 , A61M2202/064 , A61M2205/073 , A61M2205/8225 , A61M2206/16
摘要： A dispensing device, a storage device and a method for dispensing powder in which powder is dispensed through a duct with a flat cross section to de-agglomerate the powder and to generate a spray with fine particle size. A storage chamber for the powder may be closed by a bursting element which is burst by pressurized gas for discharging the powder, the gas pressure reaching or exceeding a peak value before the bursting element bursts so that the powder is dispensed at a lower gas pressure. The powder may be forced through the duct by a gas pressure of less than 300 kPa to de-agglomerate the powder and/or to generate the spray. The storage device can have multiple storage chambers and associated ducts or nozzles, so that each dose of powder can be dispensed through a separate duct or nozzle.
摘要翻译： 分配装置，存储装置和分配粉末的方法，其中通过具有平坦横截面的管道分配粉末，以使粉末解聚并产生具有细粒度的喷雾。 用于粉末的储存室可以由爆破元件封闭，该破裂元件通过用于排出粉末的加压气体爆裂，气体压力在爆裂元件爆发之前达到或超过峰值，使得粉末以较低的气体压力被分配。 可以通过小于300kPa的气体压力将粉末强制通过管道，以使粉末脱团解和/或产生喷雾。 存储装置可以具有多个存储室和相关联的管道或喷嘴，使得可以通过单独的管道或喷嘴分配每一剂量的粉末。
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公开(公告)号：US08944054B2
公开(公告)日：2015-02-03
申请号：US12296980
申请日：2007-04-13
申请人： Herbert Wachtel , Johannes Geser , Burkhard P. Metzger , Michael Spallek , Michael Krueger , Hubert Kunze , Achim Moser , Elmar Mock , Antonino Lanci , Andre Klopfenstein
发明人： Herbert Wachtel , Johannes Geser , Burkhard P. Metzger , Michael Spallek , Michael Krueger , Hubert Kunze , Achim Moser , Elmar Mock , Antonino Lanci , Andre Klopfenstein
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A61M15/0003 , A61M15/003 , A61M15/0048 , A61M15/0051 , A61M2202/064
摘要： A medicine dispensation device, in particular a multi-dose powder inhalator, for the dispensing of individual doses of medicine that has a number of medicine chambers contained in a medicine magazine shaped like a continuous loop. The medicine chambers form groups in such a manner that a mouthpiece reaches the different groups by an essentially complete rotation of the medicine magazine. This enables several medicine chambers—typically one, two or three—to be situated between two successive intake positions, which allows for a high density of medicine chambers and thus creates an inhalation device, which can be handled comfortably even when containing a great number of individual doses.
摘要翻译： 用于分配单个剂量的药物的药物分配装置，特别是多剂量粉末吸入器，其具有包含在形状类似连续环的药物盒中的多个药物室。 药盒以这样的方式形成组，即通过药盒的基本上完全的旋转使得口部到达不同的组。 这使得几个药室（通常为一个，两个或三个）位于两个连续的进入位置之间，这允许高密度的药物腔室，并且因此产生吸入装置，其可以舒适地处理，即使当包含大量 个别剂量。
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6.发明授权Medicaments magazine, and a device and method for opening it; multi-dose powder inhaler 有权药品杂志，以及打开它的装置和方法; 多剂量粉剂吸入器公开(公告)号：US08602024B2
公开(公告)日：2013-12-10
申请号：US12296984
申请日：2007-04-13
申请人： Herbert Wachtel , Johannes Geser , Burkhard Metzger , Michael Spallek , Michael Krueger , Herbert Kunze , Achim Moser , Elmar Mock , Antonino Lanci , Andre Klopfenstein
发明人： Herbert Wachtel , Johannes Geser , Burkhard Metzger , Michael Spallek , Michael Krueger , Herbert Kunze , Achim Moser , Elmar Mock , Antonino Lanci , Andre Klopfenstein
CPC分类号： A61M15/0045 , A61M15/0043 , A61M15/0051
摘要： The invention relates to a medicament magazine with a plurality of doses of medicament, wherein the magazine is formed from a single foil strip in which pouches (2) for holding a medicament are formed as depicted in exemplary FIG. 1. The foil strip comprises for transporting the strip openings (4) on at least one side for the engagement of transporting pins. The foil strip has a certain width in the region of the pouches, which is less than the width of the foil in other regions, and the openings are arranged in this broader part of the foil strip. The invention also relates to a method and a device for opening a medicament magazine of this kind, the device preferably being constructed as a segmented wheel.
摘要翻译： 本发明涉及一种具有多个剂量的药物的药物储存器，其中所述料盒由单个箔条形成，其中形成用于保持药物的袋（2），如图示例所示。 箔条包括用于在至少一个侧面上传送条形开口（4）用于输送销的接合。 箔条在袋的区域中具有一定的宽度，其小于其它区域中的箔的宽度，并且开口布置在箔条的更宽的部分中。 本发明还涉及一种用于打开这种药物盒的方法和装置，该装置优选构造为分段轮。
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7.发明授权公开(公告)号：US08561610B2
公开(公告)日：2013-10-22
申请号：US13482359
申请日：2012-05-29
申请人： Herbert Wachtel , Johannes Geser , Burkhard Metzger , Michael Spallek , Michael Krueger , Hubert Kunze , Achim Moser , Elmar Mock , Antonino Lanci , Andre Klopfenstein
发明人： Herbert Wachtel , Johannes Geser , Burkhard Metzger , Michael Spallek , Michael Krueger , Hubert Kunze , Achim Moser , Elmar Mock , Antonino Lanci , Andre Klopfenstein
CPC分类号： A61M15/0045 , A61M15/0003 , A61M15/002 , A61M15/0028 , A61M15/0035 , A61M15/0038 , A61M15/0043 , A61M15/0048 , A61M2202/064 , A61M2206/16
摘要： A medicament dispensing device, a medicament magazine thereof, and a method of removing a medicament from the medicament magazine. The inhaler has a mouthpiece (9) and an air channel (4) connected thereto, as well as a medicament magazine with at least one medicament chamber containing a powdered medicament. A drive current is produced in the air channel, while a vacuum flow (5′) can be produced by the drive current and a constriction formed in the air channel. This narrowest part of the air channel that produces the vacuum flow is connected to a removal opening (2) which communicates with a control opening (3), in order to form an emptying current through the control opening via the removal opening. In a preferred embodiment the at least one medicament chamber including the control opening, the removal opening and a fill opening are housing in the one-piece medicament magazine.
摘要翻译： 一种药物分配装置，其药物盒，以及从药物盒中去除药物的方法。 吸入器具有接口（9）和连接到其上的空气通道（4），以及具有至少一个含有粉末状药物的药物室的药剂盒。 在空气通道中产生驱动电流，而可以通过驱动电流和在空气通道中形成的收缩来产生真空流（5'）。 产生真空流的空气通道的最窄部分连接到与控制开口（3）连通的去除开口（2），以便通过去除开口形成通过控制开口的排空电流。 在优选实施例中，包括控制开口，去除开口和填充开口的至少一个药剂室容纳在一体式药剂盒中。
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8.发明申请公开(公告)号：US20120247465A1
公开(公告)日：2012-10-04
申请号：US13482359
申请日：2012-05-29
申请人： Herbert Wachtel , Johannes Geser , Burkhard Metzger , Michael Spallek , Michael Krueger , Hubert Kunze , Achim Moser , Elmar Mock , Antonino Lanci , Andre Klopfenstein
发明人： Herbert Wachtel , Johannes Geser , Burkhard Metzger , Michael Spallek , Michael Krueger , Hubert Kunze , Achim Moser , Elmar Mock , Antonino Lanci , Andre Klopfenstein
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A61M15/0003 , A61M15/002 , A61M15/0028 , A61M15/0035 , A61M15/0038 , A61M15/0043 , A61M15/0048 , A61M2202/064 , A61M2206/16
摘要： A medicament dispensing device, a medicament magazine thereof, and a method of removing a medicament from the medicament magazine. The inhaler has a mouthpiece (9) and an air channel (4) connected thereto, as well as a medicament magazine with at least one medicament chamber containing a powdered medicament. A drive current is produced in the air channel, while a vacuum flow (5′) can be produced by the drive current and a constriction formed in the air channel. This narrowest part of the air channel that produces the vacuum flow is connected to a removal opening (2) which communicates with a control opening (3), in order to form an emptying current through the control opening via the removal opening. In a preferred embodiment the at least one medicament chamber including the control opening, the removal opening and a fill opening are housing in the one-piece medicament magazine.
摘要翻译： 一种药物分配装置，其药物盒，以及从药物盒中去除药物的方法。 吸入器具有接口（9）和连接到其上的空气通道（4），以及具有至少一个含有粉末状药物的药物室的药剂盒。 在空气通道中产生驱动电流，而可以通过驱动电流和在空气通道中形成的收缩来产生真空流（5'）。 产生真空流的空气通道的最窄部分连接到与控制开口（3）连通的去除开口（2），以便通过去除开口形成通过控制开口的排空电流。 在优选实施例中，包括控制开口，去除开口和填充开口的至少一个药剂室容纳在一体式药剂盒中。
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9.发明申请公开(公告)号：US20110277753A1
公开(公告)日：2011-11-17
申请号：US12808686
申请日：2008-12-24
申请人： Stephen T. Dunne , Achim Moser
发明人： Stephen T. Dunne , Achim Moser
IPC分类号： A61M11/00
CPC分类号： A61M15/0045 , A61M11/001 , A61M15/0031 , A61M15/0043 , A61M15/0051 , A61M15/0061 , A61M2202/064 , A61M2205/07 , A61M2205/071
摘要： The invention relates to a dispensing device, a storage device and a method for dispensing a medical formulation. Multiple doses of the formulation are stored in a carrier having multiple storage members, each storage member containing a single dose. Each storage member comprises one duct or nozzle for dispensing the respective dose. The dispensing direction of the ducts or nozzles is directed in a lengthwise or indexing direction of the carrier. The storage device of the carrier is a peelable blister strip, wherein the ducts or nozzles can be opened one after the other by peeling the blister strip.
摘要翻译： 本发明涉及分配装置，存储装置和用于分配医疗制剂的方法。 将多剂量的制剂储存在具有多个储存构件的载体中，每个储存构件含有单一剂量。 每个存储构件包括用于分配相应剂量的一个管道或喷嘴。 管道或喷嘴的分配方向指向载体的纵向或分度方向。 载体的存储装置是可剥离的泡罩条，其中可以通过剥离泡罩条来一个接一个地打开导管或喷嘴。
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公开(公告)号：US09027854B2
公开(公告)日：2015-05-12
申请号：US11682604
申请日：2007-03-06
申请人： Achim Moser , Klaus Kadel
发明人： Achim Moser , Klaus Kadel
CPC分类号： B05B1/3436 , B05B15/40
摘要： A simple, compact construction and easy manufacture of a swirl nozzle having a plurality of inlet channels and an outlet channel extending transversely thereto are made possible by the fact that the inlet channels open directly and/or tangentially into the outlet channel. Alternatively or additionally, upstream of the inlet channels is provided a filter structure having smaller flow cross-sections than the inlet channels. The swirl nozzle is used, in particular, for atomizing a liquid medicament formulation. The swirl nozzle is produced from two plate-shaped components, the outlet channel first being etched as a blind bore in one component and then opened up by grinding the component away. Alternatively or additionally, the outlet channel is formed in a different component from the inlet channels.
摘要翻译： 简单紧凑的结构和易于制造具有多个入口通道和横向延伸的出口通道的旋流喷嘴由于入口通道直接和/或切向进入出口通道的事实成为可能。 替代地或另外地，入口通道的上游设置有具有比入口通道更小的流动横截面的过滤器结构。 旋涡喷嘴特别用于雾化液体药物制剂。 涡流喷嘴由两个板状部件制成，出口通道首先被作为盲孔蚀刻在一个部件中，然后通过磨削部件而打开。 或者或另外，出口通道形成在与入口通道不同的部件中。
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