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公开(公告)号：US09937306B2
公开(公告)日：2018-04-10
申请号：US13020200
申请日：2011-02-03
CPC分类号： A61M15/009 , B65D83/753 , C09K3/30
摘要： The invention relates to pharmaceutical active substances, active substance mixtures and formulations for use as an aerosol in propellant-containing [1.1.1.2-tetrafluoroethane (HFC-134a) or 1.1.1.2.3.3.3-heptafluoropropane(HFC-227)] metered-dose aerosols and the metered-dose aerosols for administering these active substances, active substance mixtures and formulations.
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2.发明授权公开(公告)号：US08297277B2
公开(公告)日：2012-10-30
申请号：US11565293
申请日：2006-11-30
CPC分类号： A61M15/0045 , A61M11/001 , A61M11/002 , A61M15/0031 , A61M15/0036 , A61M15/0048 , A61M15/0061 , A61M2202/064 , A61M2205/071 , A61M2205/8225
摘要： A dispensing device, a storage device and a method for dispensing a medical formulation are proposed. Multiple doses of the formulation are stored in a carrier having multiple inserts, each insert containing a single dose. Preferably, each insert has at least one duct or nozzle for dispensing the respective dose. Each insert is located in a separate and sealed cavity in the carrier. The cavities can be individually opened for dispensing the respective dose from the respective insert.
摘要翻译： 提出了分配装置，存储装置和用于分配医疗配方的方法。 将多剂量的制剂储存在具有多个插入物的载体中，每个插入物含有单一剂量。 优选地，每个插入物具有用于分配相应剂量的至少一个管道或喷嘴。 每个插入件位于载体中的单独且密封的空腔中。 可以单独打开空腔以从相应的插入件分配相应的剂量。
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公开(公告)号：US20120222675A1
公开(公告)日：2012-09-06
申请号：US13469631
申请日：2012-05-11
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M11/001 , A61M11/002 , A61M11/02 , A61M15/0003 , A61M15/002 , A61M15/0031 , A61M15/0033 , A61M15/0045 , A61M15/0048 , A61M15/0051 , A61M2202/064 , A61M2205/073 , A61M2205/8225 , A61M2206/16
摘要： A dispensing device, and a method for dispensing powder in which powder is dispensed through a duct with a flat cross section to de-agglomerate the powder and to generate a spray with fine particle size. A storage chamber for the powder may be closed by a bursting element which is burst by pressurized gas for discharging the powder, the gas pressure reaching or exceeding a peak value before the bursting element bursts so that the powder is dispensed at a lower gas pressure. The powder may be forced through the duct by a gas pressure of less than 300 kPa to de-agglomerate the powder and/or to generate the spray. The storage device can have multiple storage chambers and associated ducts or nozzles, so that each dose of powder can be dispensed through a separate duct or nozzle, the storage chamber and duct or nozzle being formed of a one-piece construction.
摘要翻译： 一种分配装置和分配粉末的方法，其中通过具有平坦横截面的管道分配粉末，以使粉末脱颗粒并产生具有细粒度的喷雾。 用于粉末的储存室可以由爆破元件封闭，该破裂元件通过用于排出粉末的加压气体爆裂，气体压力在爆裂元件爆发之前达到或超过峰值，使得粉末以较低的气体压力被分配。 可以通过小于300kPa的气体压力将粉末强制通过管道，以使粉末脱团解和/或产生喷雾。 存储装置可以具有多个存储室和相关联的管道或喷嘴，使得每一剂量的粉末可以通过单独的管道或喷嘴分配，储存室和管道或喷嘴由单件结构形成。
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公开(公告)号：US20080087737A1
公开(公告)日：2008-04-17
申请号：US11577647
申请日：2005-07-19
IPC分类号： B05B17/00
CPC分类号： A61L9/145 , A61L9/12 , A61L2209/22
摘要： A discharge device and a method for evaporating a liquid to the atmosphere are proposed. The liquid pressurized by gas is supplied to an evaporator via a flow restriction device which restricts the flow rate of the liquid such that continuous release and evaporation of the liquid is possible. Further, an evaporator is proposed. The evaporator comprises an evaporation surface which is designed preferably by microstructuring such that the surface area is increased and/or the liquid forms an essentially uniform film on the evaporation surface.
摘要翻译： 提出了一种将液体蒸发到大气中的放电装置和方法。 由气体加压的液体通过流量限制装置被供应到蒸发器，该流量限制装置限制液体的流速，使得液体的连续释放和蒸发是可能的。 此外，提出了一种蒸发器。 蒸发器包括优选通过微结构设计的蒸发表面，使得表面积增加和/或液体在蒸发表面上形成基本均匀的膜。
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公开(公告)号：US20070175469A1
公开(公告)日：2007-08-02
申请号：US11565280
申请日：2006-11-30
IPC分类号： A61M11/00
CPC分类号： A61M15/0065 , A61M11/001 , A61M15/0071 , A61M15/008 , A61M15/009 , B05B1/044 , B05B1/14 , B05B1/26 , B05B11/308 , B65D83/54
摘要： A dispensing device dispenses a liquid, in particular containing or formed of a drug, as a fine spray, that has a high fraction of small particles achieved by using a duct or slit having a flat cross section. Additionally or alternatively, the nozzle or duct has at least one sharp change in cross section and/or alternate sections with large and small cross-sectional areas.
摘要翻译： 分配装置将具有包含或由药物形成的液体作为细小喷雾分配，其具有通过使用具有平坦横截面的管道或狭缝获得的大部分小颗粒。 附加地或替代地，喷嘴或管道具有至少一个横截面的急剧变化和/或具有大的和小的横截面积的交替部分。
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6.发明申请公开(公告)号：US20070163574A1
公开(公告)日：2007-07-19
申请号：US11565293
申请日：2006-11-30
CPC分类号： A61M15/0045 , A61M11/001 , A61M11/002 , A61M15/0031 , A61M15/0036 , A61M15/0048 , A61M15/0061 , A61M2202/064 , A61M2205/071 , A61M2205/8225
摘要： A dispensing device, a storage device and a method for dispensing a medical formulation are proposed. Multiple doses of the formulation are stored in a carrier having multiple inserts, each insert containing a single dose. Preferably, each insert has at least one duct or nozzle for dispensing the respective dose. Each insert is located in a separate and sealed cavity in the carrier. The cavities can be individually opened for dispensing the respective dose from the respective insert.
摘要翻译： 提出了分配装置，存储装置和用于分配医疗配方的方法。 将多剂量的制剂储存在具有多个插入物的载体中，每个插入物含有单一剂量。 优选地，每个插入物具有用于分配相应剂量的至少一个管道或喷嘴。 每个插入件位于载体中的单独且密封的空腔中。 可以单独打开空腔以从相应的插入件分配相应的剂量。
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公开(公告)号：US20050017089A1
公开(公告)日：2005-01-27
申请号：US10622772
申请日：2003-07-21
申请人： Marc Rohrschneider
发明人： Marc Rohrschneider
CPC分类号： B05B11/3004 , B05B11/00412 , B05B11/3001 , B05B11/306
摘要： A finger operated spray pump has a liquid reservoir (1), a cylinder (3) for containing a portion of the liquid from the reservoir (1) which is connected at one end to an atomizer (5), a piston (6) sealingly mounted within the cylinder (3) and movable within the cylinder (3) in a spray stroke, a passageway (7) connecting the cylinder (3) with the liquid reservoir (1), a one way valve (8) at the passageway (7) for allowing a flow of liquid only from the supply of liquid (2) into the cylinder (3), and a finger operated actuator (9) which is displaceable relative to the liquid reservoir (1). The outer diameter of the piston (6) and the corresponding inner diameter of the cylinder (3) is between about 0.5 mm and about 4.0 mm, the nozzle diameter of the atomizer (5) is between 15 μm and 150 μm, the operating pressure within the cylinder (3) during the spray stroke with average finger force is between 10 bar and 400 bar and the atomizer (5), the cylinder (3), the piston (6) and the one way valve means (8) are designed to withstand the operating pressure.
摘要翻译： 手指式喷雾泵具有液体储存器（1），用于容纳来自储存器（1）的一部分液体的气缸（3），其一端连接到雾化器（5），密封地连接到活塞 安装在气缸（3）内并以喷射行程在气缸（3）内移动;将气缸（3）与液体储存器（1）连接的通道（7），通道处的单向阀（8） 7），用于允许仅从液体（2）供应到气缸（3）中的液体流动，以及可相对于液体储存器（1）移位的手指式致动器（9）。 活塞（6）的外径和气缸（3）的相应内径在约0.5mm至约4.0mm之间，雾化器（5）的喷嘴直径在15μm和150μm之间，操作压力 在喷雾冲程期间，在平均手指力为10巴与400巴之间的气缸（3）内，雾化器（5），气缸（3），活塞（6）和单向阀装置（8）被设计 承受操作压力。
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公开(公告)号：US09827384B2
公开(公告)日：2017-11-28
申请号：US13476220
申请日：2012-05-21
申请人： Holger Holakovsky , Ralf Thoemmes , Marc Rohrschneider , Florian Witte , Kevin Peter Deane , Douglas Ivan Jennings
发明人： Holger Holakovsky , Ralf Thoemmes , Marc Rohrschneider , Florian Witte , Kevin Peter Deane , Douglas Ivan Jennings
CPC分类号： A61M15/0065 , A61M11/007 , A61M11/02 , A61M15/0025 , A61M15/0036 , A61M15/0071 , A61M15/0081 , A61M15/0086 , A61M2205/273 , B05B11/0054 , B05B11/308 , B05B11/3091 , F04C2270/0421 , G06M1/026 , G06M1/24
摘要： A nebulizer is proposed which comprises a replaceable container containing fluid, a housing part detachable from the nebulizer for replacing the container, and an operation counter inseparable from the housing part as depicted in exemplary FIG. 10. The operation counter comprises a lead screw and an associated rider both supported by the housing part.
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公开(公告)号：US09617064B2
公开(公告)日：2017-04-11
申请号：US10943165
申请日：2004-09-17
申请人： Marc Rohrschneider , Waldemar Masur , Elvira Piel , Campbell Patrick , Rüdiger Belau , Karl-Heinz Lange
发明人： Marc Rohrschneider , Waldemar Masur , Elvira Piel , Campbell Patrick , Rüdiger Belau , Karl-Heinz Lange
CPC分类号： B65D83/20 , B65D83/16 , B65D83/753
摘要： A spray head for an aerosol tank, and an aerosol tank having a spray head is provided, which includes a fluid exit valve for spraying a low-solvent fluid. The fluid exit valve of the aerosol tank defines an axial fluid exit direction. The spray head includes a capillary tube for routing the fluid and for nozzle-less spraying of the fluid. An entry end of the capillary tube is axially joined to the fluid exit valve when the spray head has been seated on the aerosol tank. An exit end of the capillary tube is open to the ambient atmosphere. In the spray head, the capillary tube runs from the entry end to the exit end in an arc of approximately 90°.
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公开(公告)号：US08474454B2
公开(公告)日：2013-07-02
申请号：US12120783
申请日：2008-05-15
CPC分类号： A61M15/0045 , A61M11/001 , A61M15/0031 , A61M15/0036 , A61M15/0048 , A61M15/0061 , A61M15/0075 , A61M2016/0021 , A61M2016/0027 , A61M2016/0039 , A61M2202/064 , A61M2205/07 , A61M2205/8225
摘要： A dispensing device has a storage device and an air pump for dispensing a medical formulation. The storage device has multiple inserts, each insert containing a single dose of the formulation. Each insert is located in a separate and sealed cavity. The cavities can be individually opened for dispensing the respective dose from the respective insert by a connecting element that is moveable relative to the inserts for individually supplying air from a air pump to a respective one of the receptacles. A manually operated actuator is radially moveable to operate the air pump and to rotate the storage device to the next receptacle, and/or radially move the connecting element to individually open the respective receptacle, and to connect the pump to the respective receptacle and/or to push an insert out of the respective receptacle.
摘要翻译： 分配装置具有存储装置和用于分配医疗配方的空气泵。 存储装置具有多个插入物，每个插入物含有单剂量的制剂。 每个插入件都位于一个独立且密封的腔中。 空腔可以单独打开，以通过相对于插入件可移动的连接元件从相应的插入件分配相应的剂量，用于将空气从空气泵单独地供应到相应的一个容器。 手动操作的致动器可径向移动以操作空气泵并将存储装置旋转到下一个容器，和/或径向移动连接元件以单独打开相应的容器，并将泵连接到相应的容器和/或 将插入物推出相应的容器。
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