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公开(公告)号：US08474454B2
公开(公告)日：2013-07-02
申请号：US12120783
申请日：2008-05-15
CPC分类号： A61M15/0045 , A61M11/001 , A61M15/0031 , A61M15/0036 , A61M15/0048 , A61M15/0061 , A61M15/0075 , A61M2016/0021 , A61M2016/0027 , A61M2016/0039 , A61M2202/064 , A61M2205/07 , A61M2205/8225
摘要： A dispensing device has a storage device and an air pump for dispensing a medical formulation. The storage device has multiple inserts, each insert containing a single dose of the formulation. Each insert is located in a separate and sealed cavity. The cavities can be individually opened for dispensing the respective dose from the respective insert by a connecting element that is moveable relative to the inserts for individually supplying air from a air pump to a respective one of the receptacles. A manually operated actuator is radially moveable to operate the air pump and to rotate the storage device to the next receptacle, and/or radially move the connecting element to individually open the respective receptacle, and to connect the pump to the respective receptacle and/or to push an insert out of the respective receptacle.
摘要翻译： 分配装置具有存储装置和用于分配医疗配方的空气泵。 存储装置具有多个插入物，每个插入物含有单剂量的制剂。 每个插入件都位于一个独立且密封的腔中。 空腔可以单独打开，以通过相对于插入件可移动的连接元件从相应的插入件分配相应的剂量，用于将空气从空气泵单独地供应到相应的一个容器。 手动操作的致动器可径向移动以操作空气泵并将存储装置旋转到下一个容器，和/或径向移动连接元件以单独打开相应的容器，并将泵连接到相应的容器和/或 将插入物推出相应的容器。
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公开(公告)号：US08240305B2
公开(公告)日：2012-08-14
申请号：US12120837
申请日：2008-05-15
CPC分类号： A61M15/0045 , A61M11/001 , A61M15/0003 , A61M15/0031 , A61M15/0036 , A61M15/0061 , A61M15/0075 , A61M2016/0021 , A61M2016/0027 , A61M2016/0039 , A61M2202/064 , A61M2205/07 , A61M2205/8225
摘要： A dispensing device with a storage device and an air pump for dispensing a medical formulation in which the storage device has multiple inserts, each insert containing a single dose of the formulation. Each insert is located in a separate and sealed cavity. The cavities can be individually opened for dispensing the respective dose from the respective insert. Furthermore, a mechanism is provided for aligning the connecting element relative to a respective receptacle and/or insert which has guiding portions formed at or by the respective receptacle and/or insert.
摘要翻译： 一种具有存储装置和用于分配药物制剂的空气泵的分配装置，其中存储装置具有多个插入物，每个插入物包含单剂量的制剂。 每个插入件都位于一个独立且密封的腔中。 可以单独打开空腔以从相应的插入件分配相应的剂量。 此外，提供了一种用于使连接元件相对于相应的容器和/或插入件对准的机构，该插座和/或插入件具有形成在相应的插座和/
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公开(公告)号：US20110041844A1
公开(公告)日：2011-02-24
申请号：US12812685
申请日：2009-01-16
申请人： Stephen T. Dunne
发明人： Stephen T. Dunne
CPC分类号： A61M11/00 , A61M11/001 , A61M11/007 , A61M11/02 , A61M11/04 , A61M15/0021 , A61M15/0045 , A61M15/0065 , A61M15/009 , A61M2202/0468 , B05B1/26 , B05B11/3001 , B05B11/3091
摘要： A nozzle (12), an inhaler (FIG. 1) with a nozzle (12) and a method for producing a nozzle are proposed. The nozzle comprises two holes (21) formed in a flat plate (22). Then, the plate (21) is deformed such that the axes of the holes intersect so that jets of fluids generated by the holes impinge with each other.
摘要翻译： 提出了具有喷嘴（12）的喷嘴（12），吸入器（图1）和喷嘴的制造方法。 喷嘴包括形成在平板（22）中的两个孔（21）。 然后，板（21）变形使得孔的轴相交，使得由孔产生的流体射流相互碰撞。
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公开(公告)号：US07246615B2
公开(公告)日：2007-07-24
申请号：US10291624
申请日：2002-11-12
申请人： Frank Bartels , Wulf Bachtler , Stephen T Dunne , Joachim Eicher , Bernhard Freund , William B Hart , Christoph Lessmoellmann
发明人： Frank Bartels , Wulf Bachtler , Stephen T Dunne , Joachim Eicher , Bernhard Freund , William B Hart , Christoph Lessmoellmann
CPC分类号： F15C1/22 , A61M2205/7545 , B05B1/00 , B05B1/08 , B05B1/14 , B05B1/26 , B05B1/34 , B05B1/3405 , B05B7/0425 , B05B15/40
摘要： A nozzle assembly for use in atomizing and generating sprays from a fluid. The nozzle assembly includes two members, each with generally planar surfaces, that are joined together. A first set of channels is formed in the generally planar surface of a first one of the members to form, in cooperation with the generally planar surface of the second of the members, a plurality of filter passageways. A plenum chamber is formed in the first member. The plenum chamber is in fluid communication with and downstream of the plurality of filter passageways. A second set of channels is formed in the generally planar surface of the first member to form, in cooperation with the generally planar surface of the second member, a plurality of nozzle outlet passageways. These nozzle outlet passageways are in fluid communication with the plenum chamber. The nozzle outlet passageways include a plurality of nozzle outlets which are adapted to discharge a plurality of fluid jets that impinge on one another to thereby atomize a flow of fluid.
摘要翻译： 一种喷嘴组件，用于从流体中喷雾和产生喷雾。 喷嘴组件包括两个构件，每个构件具有大致平坦的表面，其连接在一起。 第一组通道形成在第一个构件的大致平坦的表面中，以与第二个构件的大致平坦的表面协作形成多个过滤器通道。 在第一构件中形成增压室。 增压室与多个过滤器通道流体连通和下游。 第二组通道形成在第一构件的大致平坦的表面中，以与第二构件的大致平坦的表面配合形成多个喷嘴出口通道。 这些喷嘴出口通道与增压室流体连通。 喷嘴出口通道包括多个喷嘴出口，其适于排放彼此撞击的多个流体射流，从而雾化流体流。
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公开(公告)号：US20120090603A1
公开(公告)日：2012-04-19
申请号：US13147655
申请日：2009-08-17
申请人： Stephen T. Dunne , Holger Holakovsky , Alexander Bach , Jens Besseler , Manuel Krakowka , Gilbert Wuttke
发明人： Stephen T. Dunne , Holger Holakovsky , Alexander Bach , Jens Besseler , Manuel Krakowka , Gilbert Wuttke
CPC分类号： A61M15/0065 , A61M11/007 , A61M11/06 , A61M15/009 , A61M2202/0468 , B05B11/3091 , B65D83/386 , B65D83/48 , B65D83/62
摘要： A device, cartridge and method for dispensing a liquid (103), preferably a drug, are proposed. The liquid is pressurized in a cartridge to a first lower pressure and, then, pressurized in doses by a pump (117) to a second higher pressure. A valve (106) arranged between the cartridge (100) and the pump (117) is normally closed and/or opened only temporarily. Thus, evaporation and dripping of liquid can be avoided or minimized.
摘要翻译： 提出了用于分配液体（103），优选药物的装置，盒和方法。 将液体在筒中加压至第一较低压力，然后通过泵（117）以剂量加压至第二较高压力。 布置在盒（100）和泵（117）之间的阀（106）通常仅被暂时关闭和/或打开。 因此，可以避免或最小化液体的蒸发和滴落。
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公开(公告)号：US08113196B2
公开(公告)日：2012-02-14
申请号：US12120888
申请日：2008-05-15
申请人： Marc Rohrschneider , Stephen T. Dunne , Jens Besseler , Timo Von Brunn , Ralf Thoemmes , Thomas Sowden Reinhold
发明人： Marc Rohrschneider , Stephen T. Dunne , Jens Besseler , Timo Von Brunn , Ralf Thoemmes , Thomas Sowden Reinhold
CPC分类号： A61M15/0045 , A61M11/001 , A61M15/0026 , A61M15/0036 , A61M15/0048 , A61M15/005 , A61M15/0061 , A61M15/0075 , A61M15/0081 , A61M15/0091 , A61M15/0096 , A61M2202/064 , A61M2205/07 , A61M2205/8225 , A61M2206/16
摘要： A dispensing device has a storage device and an air pump for dispensing a medical formulation. The storage device includes multiple inserts, each insert containing a single dose of the formulation. Each insert is located in a separate and sealed cavity. The cavities can be individually opened for dispensing the respective dose from the respective insert and a mechanism is provided for reinserting the inserts back into the respective receptacles after use.
摘要翻译： 分配装置具有存储装置和用于分配医疗配方的空气泵。 存储装置包括多个插入物，每个插入物含有单剂量的制剂。 每个插入件都位于一个独立且密封的腔中。 可以单独打开空腔以从相应的插入件分配相应的剂量，并且提供用于在使用后将插入件重新插入相应的容器中的机构。
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公开(公告)号：US20110168175A1
公开(公告)日：2011-07-14
申请号：US12864944
申请日：2009-02-18
CPC分类号： B05B11/0054 , A61M11/02 , A61M15/0035 , B05B11/0041 , B05B11/00412 , B05B11/0097 , B05B11/309 , B65D83/42 , B65D83/425 , B65D83/62
摘要： An inhaler including a pre-inserted cartridge (100) is proposed. The cartridge contains liquid (103) which is preferably pressurized to a low pressure. The cartridge is connected via an aerosol valve (106) with the inhaler. The liquid is further pressurized by a pump (117) of the inhaler to a high pressure and atomized.
摘要翻译： 提出了包括预插入盒（100）的吸入器。 墨盒包含优选加压至低压的液体（103）。 墨盒通过气雾阀（106）与吸入器连接。 液体被吸入器的泵（117）进一步加压至高压并雾化。
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公开(公告)号：US20080289625A1
公开(公告)日：2008-11-27
申请号：US12120837
申请日：2008-05-15
IPC分类号： A61M11/00
CPC分类号： A61M15/0045 , A61M11/001 , A61M15/0003 , A61M15/0031 , A61M15/0036 , A61M15/0061 , A61M15/0075 , A61M2016/0021 , A61M2016/0027 , A61M2016/0039 , A61M2202/064 , A61M2205/07 , A61M2205/8225
摘要： A dispensing device with a storage device and an air pump for dispensing a medical formulation in which the storage device has multiple inserts, each insert containing a single dose of the formulation. Each insert is located in a separate and sealed cavity. The cavities can be individually opened for dispensing the respective dose from the respective insert. Furthermore, a mechanism is provided for aligning the connecting element relative to a respective receptacle and/or insert which has guiding portions formed at or by the respective receptacle and/or insert.
摘要翻译： 一种具有存储装置和用于分配药物制剂的空气泵的分配装置，其中存储装置具有多个插入物，每个插入物包含单剂量的制剂。 每个插入件都位于一个独立且密封的腔中。 可以单独打开空腔以从相应的插入件分配相应的剂量。 此外，提供了一种用于使连接元件相对于相应的容器和/或插入件对准的机构，该插座和/或插入件具有形成在相应的插座和/或插入件处或由相应的插座和/或插入件形成的引导部分。
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公开(公告)号：US20080283054A1
公开(公告)日：2008-11-20
申请号：US12120783
申请日：2008-05-15
CPC分类号： A61M15/0045 , A61M11/001 , A61M15/0031 , A61M15/0036 , A61M15/0048 , A61M15/0061 , A61M15/0075 , A61M2016/0021 , A61M2016/0027 , A61M2016/0039 , A61M2202/064 , A61M2205/07 , A61M2205/8225
摘要： A dispensing device has a storage device and an air pump for dispensing a medical formulation. The storage device has multiple inserts, each insert containing a single dose of the formulation. Each insert is located in a separate and sealed cavity. The cavities can be individually opened for dispensing the respective dose from the respective insert by a connecting element that is moveable relative to the inserts for individually supplying air from a air pump to a respective one of the receptacles. A manually operated actuator is radially moveable to operate the air pump and to rotate the storage device to the next receptacle, and/or radially move the connecting element to individually open the respective receptacle, and to connect the pump to the respective receptacle and/or to push an insert out of the respective receptacle.
摘要翻译： 分配装置具有存储装置和用于分配医疗配方的空气泵。 存储装置具有多个插入物，每个插入物含有单剂量的制剂。 每个插入件都位于一个独立且密封的腔中。 空腔可以单独打开，以通过相对于插入件可移动的连接元件从相应的插入件分配相应的剂量，用于将空气从空气泵单独地供应到相应的一个容器。 手动操作的致动器可径向移动以操作空气泵并将存储装置旋转到下一个容器，和/或径向移动连接元件以单独打开相应的容器，并将泵连接到相应的容器和/或 将插入物推出相应的容器。
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公开(公告)号：US5497944A
公开(公告)日：1996-03-12
申请号：US938174
申请日：1992-11-19
IPC分类号： A61M11/00 , A61M11/02 , A61M15/00 , B05B1/26 , B05B1/34 , B05B9/08 , B05B11/00 , B05B15/00 , G01F11/02
CPC分类号： B05B15/008 , A61M11/001 , A61M15/0065 , B05B1/26 , B05B1/265 , B05B11/004 , B05B11/0043 , B05B11/3001 , B05B11/3074 , B05B11/3091 , B05B9/0883 , G01F11/025 , B05B1/3436
摘要： A metered dose inhaler for dispensing a fluid medicament as droplets of small mean particle size without the use of pressurized gas or liquefied propellants. A liquid drug is contained in a fluid reservoir, and metered quantities of the drug are successively presented into a reduced cross-section pressure chamber, with non-return valves controlling the flow of liquid through the device. The metered quantity of the drug is then subjected to a sudden and great increase in pressure by releasing a piston into the pressure chamber. The liquid drug is thereby ejected through an atomizing head, to reduce it to a fine atomized spray of small mean particle size, preferably less than approximately 12 micrometers.
摘要翻译： PCT No.PCT / GB91 / 00433 Sec。 371日期：1992年11月19日 102（e）日期1992年11月19日PCT 1991年3月21日PCT公布。 WO91 / 14468 PCT出版物 日期1991年10月3日。一种计量吸入器，用于在不使用加压气体或液化推进剂的情况下将流体药物分散成小平均粒径的液滴。 液体药物包含在流体储存器中，并且计量的药物被连续地呈现在减小的横截面压力室中，止回阀控制液体通过该装置的流动。 然后通过将活塞释放到压力室中，计量的药物经受突然而大的压力升高。 液体药物由此喷射通过雾化头，以将其减小到平均粒度小的优选雾化喷雾，优选小于约12微米。
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