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    Solvent-resistant microorganisms
    2.
    发明授权
    Solvent-resistant microorganisms 失效
    耐溶剂微生物

    公开(公告)号：US5807735A

    公开(公告)日：1998-09-15

    申请号：US831400

    申请日：1997-04-01

    申请人： Alexander A. Klibanov ,  Kim Lewis ,  Anthony Ferrante ,  Catherine L. Coyle ,  Gerben Zylstra ,  Michael S. P. Logan ,  Matthew J. Grossman

    发明人： Alexander A. Klibanov ,  Kim Lewis ,  Anthony Ferrante ,  Catherine L. Coyle ,  Gerben Zylstra ,  Michael S. P. Logan ,  Matthew J. Grossman

    IPC分类号： C12N9/02 ,  C12N9/08 ,  C12N15/52 ,  C12N15/53 ,  C12N15/70 ,  C07H21/04 ,  C12N9/04

    CPC分类号： C12N9/0036 ,  C12N15/52 ,  C12N9/0065 ,  C12R1/19

    摘要： The present invention includes microorganisms that are resistant to non-aqueous solvents. In addition, the organisms of interest are able to grow and/or carry out various organic (e.g. hydrocarbon) transformations in non-aqueous/aqueous mixtures. The invention also includes a gene which encodes an enzyme, hydroperoxide reductase, which renders the host microorganism resistant to many organic solvents. The invention also includes the operon which includes the mutant gene and the ahpF gene which encodes an NAD(P)H dehydrogenase. The invention also includes a plasmid vehicle and a host microorganism containing these genes. The invention also includes cloning the genes encoding for solvent-resistance into other organisms rendering them solvent-resistant. In addition, the genes encoding for a specific organic or hydrocarbon transformation are placed into the solvent resistant microorganism.

    摘要翻译： 本发明包括耐非水溶剂的微生物。 此外，感兴趣的生物体能够在非水/含水混合物中生长和/或进行各种有机（例如烃）转化。 本发明还包括编码酶，氢过氧化物还原酶的基因，其使得宿主微生物对许多有机溶剂具有抗性。 本发明还包括包含突变基因和编码NAD（P）H脱氢酶的ahpF基因的操纵子。 本发明还包括质粒载体和含有这些基因的宿主微生物。 本发明还包括将编码耐溶剂性的基因克隆到其具有耐溶剂性的其他生物体中。 此外，将编码特异性有机或烃转化的基因置于耐溶剂微生物中。

    ELECTROLYTIC SYSTEM AND METHOD FOR FILTERING AN AQUEOUS PARTICULATE SUSPENSION
    3.
    发明申请
    ELECTROLYTIC SYSTEM AND METHOD FOR FILTERING AN AQUEOUS PARTICULATE SUSPENSION 有权
    电泳系统和过滤颗粒悬浮液的方法

    公开(公告)号：US20120091000A1

    公开(公告)日：2012-04-19

    申请号：US13249322

    申请日：2011-09-30

    申请人： E. Jennings Taylor ,  Maria I. Inman ,  Joseph Kell ,  Heather McCrabb ,  Anthony Ferrante ,  Ross Youngs ,  John Nicholas Meister ,  James Robert Cook

    发明人： E. Jennings Taylor ,  Maria I. Inman ,  Joseph Kell ,  Heather McCrabb ,  Anthony Ferrante ,  Ross Youngs ,  John Nicholas Meister ,  James Robert Cook

    IPC分类号： B01D57/02

    CPC分类号： C02F1/46104 ,  B01D57/02 ,  C02F2201/461

    摘要： An electrolytic filtration method and apparatus for the concentration and collection of suspended particulates from aqueous solutions is disclosed. The electrolytic cell contains at least an anode and a cathode, and in one embodiment contains a plurality of anodes and cathodes. The electrolytic cell also contains a filter, and in one embodiment the filter is a moving belt filter. While not bound by theory, the electrolytic filtration method and apparatus is based on the electrophoretic movement of algae particles suspended in an aqueous solution away from the filter under the influence of an electric field. In one embodiment the electric field is a pulsed waveform with unidirectional voltage or current pulses. In another embodiment, the electric field is a pulsed waveform with bidirectional voltage or current pulses.

    摘要翻译： 公开了一种用于从水溶液中浓缩和收集悬浮颗粒的电解过滤方法和装置。 电解槽至少包含阳极和阴极，并且在一个实施例中包含多个阳极和阴极。 电解槽还包含过滤器，在一个实施例中，过滤器是移动带式过滤器。 在不受理论约束的情况下，电解过滤方法和装置基于在电场的影响下悬浮在水溶液中的藻类颗粒离开过滤器的电泳运动。 在一个实施例中，电场是具有单向电压或电流脉冲的脉冲波形。 在另一个实施例中，电场是具有双向电压或电流脉冲的脉冲波形。

    Electrolytic system and method for filtering an aqueous particulate suspension
    5.
    发明授权
    Electrolytic system and method for filtering an aqueous particulate suspension 有权
    用于过滤水性颗粒悬浮液的电解系统和方法

    公开(公告)号：US09095808B2

    公开(公告)日：2015-08-04

    申请号：US13249322

    申请日：2011-09-30

    申请人： E. Jennings Taylor ,  Maria I. Inman ,  Joseph Kell ,  Heather McCrabb ,  Anthony Ferrante ,  Ross Youngs ,  John Nicholas Meister ,  James Robert Cook

    发明人： E. Jennings Taylor ,  Maria I. Inman ,  Joseph Kell ,  Heather McCrabb ,  Anthony Ferrante ,  Ross Youngs ,  John Nicholas Meister ,  James Robert Cook

    IPC分类号： B01D57/02

    CPC分类号： C02F1/46104 ,  B01D57/02 ,  C02F2201/461

    摘要： An electrolytic filtration method and apparatus for the concentration and collection of suspended particulates from aqueous solutions is disclosed. The electrolytic cell contains at least an anode and a cathode, and in one embodiment contains a plurality of anodes and cathodes. The electrolytic cell also contains a filter, and in one embodiment the filter is a moving belt filter. While not bound by theory, the electrolytic filtration method and apparatus is based on the electrophoretic movement of algae particles suspended in an aqueous solution away from the filter under the influence of an electric field. In one embodiment the electric field is a pulsed waveform with unidirectional voltage or current pulses. In another embodiment, the electric field is a pulsed waveform with bidirectional voltage or current pulses.

    摘要翻译： 公开了一种用于从水溶液中浓缩和收集悬浮颗粒的电解过滤方法和装置。 电解槽至少包含阳极和阴极，并且在一个实施例中包含多个阳极和阴极。 电解槽还包含过滤器，在一个实施例中，过滤器是移动带式过滤器。 在不受理论约束的情况下，电解过滤方法和装置基于在电场的影响下悬浮在水溶液中的藻类颗粒离开过滤器的电泳运动。 在一个实施例中，电场是具有单向电压或电流脉冲的脉冲波形。 在另一个实施例中，电场是具有双向电压或电流脉冲的脉冲波形。

    USES OF RAGE ANTAGONISTS FOR TREATING OBESITY AND RELATED DISEASES
    8.
    发明申请
    USES OF RAGE ANTAGONISTS FOR TREATING OBESITY AND RELATED DISEASES 审中-公开
    用于治疗肥胖和相关疾病的RAGE ANTAGONISTS的用途

    公开(公告)号：US20100254983A1

    公开(公告)日：2010-10-07

    申请号：US12451894

    申请日：2008-06-06

    申请人： Ann Marie Schmidt ,  Anthony Ferrante ,  Fei Song

    发明人： Ann Marie Schmidt ,  Anthony Ferrante ,  Fei Song

    IPC分类号： A61K39/395 ,  A61K38/16 ,  A61K31/415 ,  A61K31/695 ,  A61P3/06 ,  A61P3/04 ,  A61P3/10

    CPC分类号： A61K31/415

    摘要： This invention provides a method for treating obesity in which comprises administering to the subject an antagonist of a receptor for advanced glycation end products (RAGE) in an amount effective to inhibit binding of a ligand of RAGE to RAGE so as to thereby treat obesity in the subject. The present invention also provides a method for treating hyperglycemia and increased cholesterol, insulin, triglyceride and leptin levels comprising administering to the subject an antagonist of RAGE in an amount effective to inhibit binding of a ligand of RAGE to RAGE so as to thereby treat hyperglycemia and lower cholesterol, insulin, triglyceride and leptin levels on the subject.

    摘要翻译： 本发明提供一种治疗肥胖症的方法，其中包括以有效抑制RAGE配体与RAGE的结合的量向受试者施用晚期糖基化终产物（RAGE）的受体拮抗剂，从而治疗肥胖症 学科。 本发明还提供了一种治疗高血糖症和增加胆固醇，胰岛素，甘油三酯和瘦素水平的方法，其包括以有效抑制RAGE配体与RAGE结合的量向受试者施用RAGE拮抗剂，从而治疗高血糖， 降低胆固醇，胰岛素，甘油三酯和瘦素水平。