公开(公告)号：US09347931B2

公开(公告)日：2016-05-24

申请号：US13265813

申请日：2010-04-23

申请人： Anthony Joseph Killard ,  Magdalena Maria Dudek ,  Brian MacCraith ,  Ib Mendel-Hartvig ,  Ove Öhman

发明人： Anthony Joseph Killard ,  Magdalena Maria Dudek ,  Brian MacCraith ,  Ib Mendel-Hartvig ,  Ove Öhman

IPC分类号： G01N33/00 ,  G01N33/49 ,  G01N33/543 ,  G01N33/545 ,  G01N33/558 ,  G01N33/86 ,  B01L3/00

CPC分类号： G01N33/4905 ,  B01L3/502707 ,  B01L3/502753 ,  B01L2300/161 ,  B01L2400/0406 ,  B01L2400/086 ,  G01N33/54353 ,  G01N33/545 ,  G01N33/558 ,  G01N33/86

摘要： The present invention is directed to a lateral flow assay device for the monitoring and measuring of coagulation and method thereof. Ideally, the invention is directed to a lateral capillary flow device for the monitoring and/or measurement of coagulation in a liquid sample wherein the device comprises a non-porous substrate with a zone for receiving a sample and a defined flow path zone wherein a clotting agent is deposited on at least part of the defined flow path zone to accelerate the coagulation of the liquid sample, enable the formation of an evenly distributed clot along the defined flow path zone and to result in the change in flow rate or cessation of flow of the liquid sample along the defined flow path zone.

摘要翻译： 本发明涉及一种用于监测和测量凝血的侧流测定装置及其方法。 理想地，本发明涉及用于监测和/或测量液体样品中的凝结的侧向毛细管流动装置，其中该装置包括具有用于接收样品的区域和限定的流动路径区域的无孔基材，其中凝固 试剂沉积在限定的流动路径区的至少部分上以加速液体样品的凝结，使得能够沿着限定的流动路径区形成均匀分布的凝块，并导致流速的变化或流动停止 液体样品沿着限定的流路区域。

公开(公告)号：US20120107851A1

公开(公告)日：2012-05-03

申请号：US13265813

申请日：2010-04-23

申请人： Anthony Joseph Killard ,  Magdalena Maria Dudek ,  Brian MacCraith ,  Ib Mendel-Hartvig ,  Ove Öhman

发明人： Anthony Joseph Killard ,  Magdalena Maria Dudek ,  Brian MacCraith ,  Ib Mendel-Hartvig ,  Ove Öhman

IPC分类号： C12Q1/56 ,  B05D3/04 ,  G01N33/86 ,  G01N33/68 ,  C12M1/40

CPC分类号： G01N33/4905 ,  B01L3/502707 ,  B01L3/502753 ,  B01L2300/161 ,  B01L2400/0406 ,  B01L2400/086 ,  G01N33/54353 ,  G01N33/545 ,  G01N33/558 ,  G01N33/86

摘要： The present invention is directed to a lateral flow assay device for the monitoring and measuring of coagulation and method thereof. Ideally, the invention is directed to a lateral capillary flow device for the monitoring and/or measurement of coagulation in a liquid sample wherein the device comprises a non-porous substrate with a zone for receiving a sample and a defined flow path zone wherein a clotting agent is deposited on at least part of the defined flow path zone to accelerate the coagulation of the liquid sample, enable the formation of an evenly distributed clot along the defined flow path zone and to result in the change in flow rate or cessation of flow of the liquid sample along the defined flow path zone.

摘要翻译： 本发明涉及一种用于监测和测量凝血的侧流测定装置及其方法。 理想地，本发明涉及用于监测和/或测量液体样品中的凝结的侧向毛细管流动装置，其中该装置包括具有用于接收样品的区域和限定的流动路径区域的无孔基材，其中凝固 试剂沉积在限定的流动路径区的至少部分上以加速液体样品的凝结，使得能够沿着限定的流动路径区形成均匀分布的凝块，并导致流速的变化或流动停止 液体样品沿着限定的流路区域。