利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

15 条记录 (耗时 0.014 秒)

    Method for measuring recirculation in catheters
    1.
    发明授权
    Method for measuring recirculation in catheters 失效
    测量导管再循环的方法

    公开(公告)号：US08523798B2

    公开(公告)日：2013-09-03

    申请号：US12839272

    申请日：2010-07-19

    申请人： Attilio E. Difiore

    发明人： Attilio E. Difiore

    IPC分类号： A61M37/00 ,  C02F1/44

    CPC分类号： A61M1/3653 ,  A61M1/3658 ,  A61M1/3659 ,  A61M1/3661 ,  A61M2209/02

    摘要： A system and method for measuring recirculation of blood in a catheter designed for implantation in a human is described. In one variation, the system comprises an artificial circulatory system and an ultrasonic detection device for measuring and comparing the density of a circulated blood simulant with a later introduced bolus saline. The system may be configured to simulate a human heart by providing the flow, pressure and dimensions of a typical human heart. In addition to simulating the circulatory system of a normal human heart, the system may also be configured to simulate particular negative conditions of a patient, such as stenotic condition, which would affect the recirculation measurement.

    摘要翻译： 描述了一种用于测量设计用于植入人体的导管中的血液再循环的系统和方法。 在一个实施例中，该系统包括人造循环系统和用于测量和比较循环血液模拟物的浓度与稍后引入的推注盐水的超声波检测装置。 该系统可以被配置为通过提供典型人类心脏的流动，压力和尺寸来模拟人的心脏。 除了模拟正常人心脏的循环系统之外，系统还可以被配置为模拟患者的特定负面状况，例如狭窄状况，其将影响再循环测量。

    Reduction of Recirculation in Catheters
    2.
    发明申请
    Reduction of Recirculation in Catheters 审中-公开
    减少导尿管再循环

    公开(公告)号：US20120089115A1

    公开(公告)日：2012-04-12

    申请号：US13329166

    申请日：2011-12-16

    申请人： Attilio E. Difiore ,  Daniel J. Triplett

    发明人： Attilio E. Difiore ,  Daniel J. Triplett

    IPC分类号： A61M25/14

    CPC分类号： A61M25/0068 ,  A61M25/0071 ,  A61M2025/0073 ,  A61M2206/14

    摘要： A catheter tip designed to reduce the outflow velocity and/or directional momentum of fluid being infused by a catheter having such a tip. In one variation, a plurality of channels is provided at the distal portion of the catheter to increase the outflow cross-sectional area. In another variation, the diameter of the catheter at its distal portion where the fluid exits is increased. In yet another variation, a bullet-shaped nose is implemented which may decrease turbulence at the distal end of catheter tip. The low velocity outflow catheter tip may also be implemented on a dual lumen catheter, such as a hemodialysis catheter, to reduce recirculation rate. Various device configurations and methods for such implementations are also disclosed.

    摘要翻译： 导管末端设计成减少由具有这种尖端的导管注入的流体的流出速度和/或方向动量。 在一个变型中，多个通道设置在导管的远端部分以增加流出横截面积。 在另一个变型中，导管在其远端部分处出口的直径增加。 在又一个变型中，实现了子弹形鼻，其可以减小导管尖端远端处的湍流。 低速流出导管尖端还可以在诸如血液透析导管的双腔导管上实现，以减少再循环率。 还公开了用于这种实现的各种设备配置和方法。

    Bolus tip design for a multi-lumen catheter
    7.
    发明授权
    Bolus tip design for a multi-lumen catheter 失效
    多腔导管螺栓尖设计

    公开(公告)号：US07938795B2

    公开(公告)日：2011-05-10

    申请号：US12362073

    申请日：2009-01-29

    申请人： Attilio E. DiFiore ,  Leonard J. Decant, Jr. ,  Vincent J. Belusko

    发明人： Attilio E. DiFiore ,  Leonard J. Decant, Jr. ,  Vincent J. Belusko

    IPC分类号： A61M3/00

    CPC分类号： A61M25/0069 ,  A61M1/16 ,  A61M1/3653 ,  A61M1/3659 ,  A61M1/3661 ,  A61M25/0023 ,  A61M25/003 ,  A61M25/0032 ,  A61M25/0068 ,  A61M25/008 ,  A61M2025/0031 ,  A61M2025/0034 ,  A61M2025/0037 ,  A61M2025/0081

    摘要： A method of making a multi-lumen catheter includes forming a catheter body including a first lumen and a second lumen, and forming a catheter tip having a first channel terminating distally in a first opening on a first side of the catheter tip, and a second channel terminating distally in a second opening on a second side of the catheter tip opposite of the first side. The first and second openings of the catheter tip extend through an outer wall of the catheter tip to a dividing section. The catheter tip is affixed to the catheter body such that the first channel is aligned with the first lumen and the second channel is aligned with the second lumen.

    摘要翻译： 制造多腔导管的方法包括形成包括第一腔和第二腔的导管主体，以及形成导管末端，所述导管末端具有在导管末端的第一侧上的第一开口中的远端终止的第一通道， 通道在导管尖端的与第一侧相对的第二侧上的第二开口中远端终止。 导管尖端的第一和第二开口延伸穿过导管尖端的外壁到分隔部分。 导管尖端固定到导管主体，使得第一通道与第一管腔对准并且第二通道与第二管腔对准。

    METHOD FOR MEASURING RECIRCULATION IN CATHETERS
    8.
    发明申请
    METHOD FOR MEASURING RECIRCULATION IN CATHETERS 失效
    测量导管重建方法

    公开(公告)号：US20100280805A1

    公开(公告)日：2010-11-04

    申请号：US12839272

    申请日：2010-07-19

    申请人： Attilio E. Difiore

    发明人： Attilio E. Difiore

    IPC分类号： G06G7/48 ,  G01N9/32

    CPC分类号： A61M1/3653 ,  A61M1/3658 ,  A61M1/3659 ,  A61M1/3661 ,  A61M2209/02

    摘要： A system and method for measuring recirculation of blood in a catheter designed for implantation in a human is described. In one variation, the system comprises an artificial circulatory system and an ultrasonic detection device for measuring and comparing the density of a circulated blood simulant with a later introduced bolus saline. The system may be configured to simulate a human heart by providing the flow, pressure and dimensions of a typical human heart. In addition to simulating the circulatory system of a normal human heart, the system may also be configured to simulate particular negative conditions of a patient, such as stenotic condition, which would affect the recirculation measurement.

    摘要翻译： 描述了一种用于测量设计用于植入人体的导管中的血液再循环的系统和方法。 在一个实施例中，该系统包括人造循环系统和用于测量和比较循环血液模拟物的浓度与稍后引入的推注盐水的超声波检测装置。 该系统可以被配置为通过提供典型人类心脏的流动，压力和尺寸来模拟人的心脏。 除了模拟正常人心脏的循环系统之外，系统还可以被配置为模拟患者的特定负面状况，例如狭窄状况，其将影响再循环测量。

    Active iontophoresis delivery system
    9.
    发明申请
    Active iontophoresis delivery system 审中-公开
    主动离子电渗传递系统

    公开(公告)号：US20080188791A1

    公开(公告)日：2008-08-07

    申请号：US11701749

    申请日：2007-02-02

    申请人： Attilio E. DiFiore ,  Jamal S. Yanaki

    发明人： Attilio E. DiFiore ,  Jamal S. Yanaki

    IPC分类号： A61N1/30

    CPC分类号： A61N1/303

    摘要： A fully integrated, independently accurately performing, active transdermal medicament patch includes a flexible substrate with an adhesive-coated therapeutic face carrying a medicament reservoir. A circuit non-removably carried on the substrate and driven by a light-weight power source causes a substantially constant current to flow for a predetermined therapy period through the reservoir and the skin against which the therapeutic face is disposed. Net electrical polarity of the medicament determines the interconnection of circuit and power source to skin. The circuit includes a field effect transistor or an operational amplifier with a zener diode or a voltage regulator. A timer non-removably carried on the substrate disables the circuit following functioning the therapy period. An active transdermal medicament delivery system employs a single patch or pair of patches physically and electrically connected by a distensible tether.

    摘要翻译： 完全整合的，独立准确地执行的活性透皮药物贴片包括具有携带药物储存器的粘合剂涂覆的治疗面的柔性基底。 不可拆卸地承载在基板上并由轻量电源驱动的电路使得基本上恒定的电流通过储存器和治疗面设置的皮肤流过预定的治疗周期。 药物的净电极性确定电路和电源与皮肤的互连。 该电路包括场效应晶体管或具有齐纳二极管或电压调节器的运算放大器。 不可拆卸地携带在基板上的计时器在治疗期间起作用后使电路不起作用。 活性透皮药物递送系统采用单个贴片或一对贴片，其通过可扩张系绳物理和电连接。

    Method for measuring recirculation in catheters
    10.
    发明授权
    Method for measuring recirculation in catheters 有权
    测量导管再循环的方法

    公开(公告)号：US07758530B2

    公开(公告)日：2010-07-20

    申请号：US10986400

    申请日：2004-11-10

    申请人： Attilio E. Difiore ,  Mark E. Walton

    发明人： Attilio E. Difiore ,  Mark E. Walton

    IPC分类号： A61M37/00 ,  C02F1/00

    CPC分类号： A61M1/3653 ,  A61M1/3658 ,  A61M1/3659 ,  A61M1/3661 ,  A61M2209/02

    摘要： A system and method for measuring recirculation of blood in a catheter designed for implantation in a human is described. In one variation, the system comprises an artificial circulatory system and an ultrasonic detection device for measuring and comparing the density of a circulated blood simulant with a later introduced bolus saline. The system may be configured to simulate a human heart by providing the flow, pressure and dimensions of a typical human heart. In addition to simulating the circulatory system of a normal human heart, the system may also be configured to simulate particular negative conditions of a patient, such as stenotic condition, which would affect the recirculation measurement.

    摘要翻译： 描述了一种用于测量设计用于植入人体的导管中的血液再循环的系统和方法。 在一个实施例中，该系统包括人造循环系统和用于测量和比较循环血液模拟物的浓度与稍后引入的推注盐水的超声波检测装置。 该系统可以被配置为通过提供典型人类心脏的流动，压力和尺寸来模拟人的心脏。 除了模拟正常人心脏的循环系统之外，系统还可以被配置为模拟患者的特定负面状况，例如狭窄状况，其将影响再循环测量。